Candidemia from a Urinary Tract Source: Microbiological Aspects and Clinical Significance
Open accessAbstract
Twenty-six cases of candidemia associated with a well-defined urinary tract source were retrospectively identified and reviewed. Urinary tract abnormalities were present in 23 of 26 patients (88%), 19 (73%) of whom had urinary tract obstruction. Nineteen patients had undergone urinary tract procedures before the onset of candidemia. Episodes of candidemia were brief and low-grade in intensity (median duration, 1 day; median colony count, 1.5 cfu/10 mL of blood). Only eight patients (31%) received > or = 500 mg of amphotericin B. There were five in-hospital deaths (19%); two of these deaths were attributed to candidiasis. No late complications of candidemia were documented for the surviving patients. Patients with urologic pathology and candiduria who undergo surgery or manipulation of the urinary tract are at significant risk for candidemia, and further studies should examine the issue of administration of prophylaxis to this group.
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Candiduria may rarely be the source of subsequent dissemination or a marker of acute hematogenous dissemination.
“candiduria may rarely be the source of subsequent dissemination [170] or a marker of acute hematogenous dissemination [166].”
From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [170]
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- Authors
- Ang, B. S. P., Telenti, A., King, B., Steckelberg, J. M., & Wilson, W. R.
- Affiliations
- University of Bern (CH)
- Corresponding author
- Ang, B. S. P.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1993-10-01
- Volume
- 17
- Issue
- 4
- Pages
- 662-666
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2074666847
- Cited by
- 132
- References
- 18
- Citations by year
- 2026: 1 · 2023: 2 · 2022: 5 · 2021: 3 · 2020: 4 · 2019: 4 · 2018: 2 · 2017: 6 · 2016: 6 · 2015: 6 · 2014: 2 · 2013: 5 · 2012: 3
- FWCI
- 1.65
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- reroDoc Digital Library (submittedVersion)
- Bern Open Repository and Information System (University of Bern) (submittedVersion, other-oa)
- IRIS (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- Open Access CRIS of the University of Bern
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Epidemiology › Urinary Tract Infections Management
- Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
- Keywords
- candidemia, urinary tract obstruction, urinary tract anomalies, candiduria, amphotericin B, antifungal prophylaxis
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Amphotericin B, Candidiasis, Female, Humans, Male, Middle Aged, Postoperative Complications, Retrospective Studies, Urinary Tract, Urinary Tract Infections, Urine, Urography, Urologic Diseases, Fungemia, Treatment Outcome
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