Mechanism of open complex and dual incision formation by human nucleotide excision repair factors

Mammalian DNA nucleotide excision repair reconstituted with purified protein components

Aboussekhra, A., Biggerstaff, M., Shivji, M. K. K., Vilpo, J. A., Moncollin, V., Podust, V. N., Protić, M., Hübscher, U., Egly, J.-M., & Wood, R. D. (1995) · Cell · doi:10.1016/0092-8674(95)90289-9 · Cited by 837 · see citing works

Proliferating cell nuclear antigen is required for DNA excision repair

Shivji, M. K. K., Kenny, M. K., & Wood, R. D. (1992) · Cell · doi:10.1016/0092-8674(92)90416-a · Cited by 803 · see citing works

DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor

Schaeffer, L., Roy, R., Humbert, S., Moncollin, V., Vermeulen, W., Hoeijmakers, J. H. J., Chambon, P., & Egly, J. (1993) · Science · doi:10.1126/science.8465201 · Cited by 794 · see citing works

Xeroderma Pigmentosum Group F Caused by a Defect in a Structure-Specific DNA Repair Endonuclease

Sijbers, A. M., de Laat, W. L., Ariza, R. R., Biggerstaff, M., Wei, Y.-F., Moggs, J. G., Carter, K. C., Shell, B. K., Evans, E. L., de Jong, M. C., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)80155-5 · Cited by 546 · see citing works

XPG endonuclease makes the 3′ incision in human DNA nucleotide excision repair

O’Donovan, A., Davies, A. A., Moggs, J. G., West, S. C., & Wood, R. D. (1994) · Nature · doi:10.1038/371432a0 · Cited by 487 · see citing works

A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome

Weeda, G., van Ham, R. C. A., Vermeulen, W., Bootsma, D., van der Eb, A. J., & Hoeijmakers, J. H. J. (1990) · Cell · doi:10.1016/0092-8674(90)90122-u · Cited by 435 · see citing works

RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

He, Z., Henricksen, L. A., Wold, M. S., & Ingles, C. J. (1995) · Nature · doi:10.1038/374566a0 · Cited by 389 · see citing works

The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor.

Schaeffer, L., Moncollin, V., Roy, R., Staub, A., Mezzina, M., Sarasin, A. R., Weeda, G., Hoeijmakers, J. H. J., & Egly, J. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06522.x · Cited by 381 · see citing works

Reaction Mechanism of Human DNA Repair Excision Nuclease

Mu, D., Hsu, D. S., & Sancar, A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.14.8285 · Cited by 374 · see citing works

Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

Feaver, W. J., Svejstrup, J. Q., Bardwell, L., Bardwell, A. J., Buratowski, S., Gulyas, K. D., Donahue, T. F., Friedberg, E. C., & Kornberg, R. D. (1993) · Cell · doi:10.1016/0092-8674(93)90624-y · Cited by 319 · see citing works

Human xeroderma pigmentosum group D gene encodes a DMA helicase

Sung, P., Bailly, V., Weber, C. A., Thompson, L. H., Prakash, L., & Prakash, S. (1993) · Nature · doi:10.1038/365852a0 · Cited by 310 · see citing works

Specific association between the human DNA repair proteins XPA and ERCC1.

Li, L., Elledge, S. J., Peterson, C. A., Bales, E. S., & Legerski, R. J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.11.5012 · Cited by 303 · see citing works

DNA unwinding produced by site-specific intrastrand crosslinks of the antitumor drug cis-diamminedichloroplatinum(II)

Bellon, S. F., Coleman, J. H., & Lippard, S. J. (1991) · Biochemistry · doi:10.1021/bi00246a021 · Cited by 293 · see citing works

Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA

Jones, C. J., & Wood, R. D. (1993) · Biochemistry · doi:10.1021/bi00096a021 · Cited by 291 · see citing works

Mutation of lysine‐48 to arginine in the yeast RAD3 protein abolishes its ATPase and DNA helicase activities but not the ability to bind ATP.

Sung, P., Higgins, D. R., Prakash, L., & Prakash, S. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb03193.x · Cited by 264 · see citing works

Opening of an RNA polymerase II promoter occurs in two distinct steps and requires the basal transcription factors IIE and IIH.

Holstege, F. C. P., van der Vliet, P. C., & Timmers, H. T. M. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00512.x · Cited by 257 · see citing works

An Interaction between the DNA Repair Factor XPA and Replication Protein A Appears Essential for Nucleotide Excision Repair

Li, L., Lu, X., Peterson, C. A., & Legerski, R. J. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.10.5396 · Cited by 252 · see citing works

Transcription‐coupled repair removes both cyclobutane pyrimidine dimers and 6‐4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts.

van Hoffen, A., Venema, J., Meschini, R., van Zeeland, A. A., & Mullenders, L. H. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07010.x · Cited by 242 · see citing works

Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein

Evans, E. L., Fellows, J., Coffer, A. I., & Wood, R. D. (1997) · The EMBO Journal · doi:10.1093/emboj/16.3.625 · Cited by 237 · see citing works

The multiple roles of transcription/repair factor TFIIH

Svejstrup, J. Q., Vichi, P., & Egly, J. (1996) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)10046-3 · Cited by 227 · see citing works

Analysis of Incision Sites Produced by Human Cell Extracts and Purified Proteins during Nucleotide Excision Repair of a 1,3-Intrastrand d(GpTpG)-Cisplatin Adduct

Moggs, J. G., Yarema, K. J., Essigmann, J. M., & Wood, R. D. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.12.7177 · Cited by 205 · see citing works

Interactions Involving the Human RNA Polymerase II Transcription/Nucleotide Excision Repair Complex TFIIH, the Nucleotide Excision Repair Protein XPG, and Cockayne Syndrome Group B (CSB) Protein

Iyer, N. V., Reagan, M. S., Wu, K.-J., Canagarajah, B. J., & Friedberg, E. C. (1996) · Biochemistry · doi:10.1021/bi9524124 · Cited by 199 · see citing works

RAD25 is a DMA helicase required for DNA repair and RNA polymerase II transcription

Guzder, S. N., Sung, P., Bailly, V., Prakash, L., & Prakash, S. (1994) · Nature · doi:10.1038/369578a0 · Cited by 193 · see citing works

The General Transcription-Repair Factor TFIIH Is Recruited to the Excision Repair Complex by the XPA Protein Independent of the TFIIE Transcription Factor

Park, C.-H., Mu, D., Reardon, J. T., & Sancar, A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.9.4896 · Cited by 191 · see citing works

Co‐correction of the ERCC1, ERCC4 and xeroderma pigmentosum group F DNA repair defects in vitro.

Biggerstaff, M., Szymkowski, D. E., & Wood, R. D. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06043.x · Cited by 171 · see citing works

The Non-catalytic Function of XPG Protein during Dual Incision in Human Nucleotide Excision Repair

Wakasugi, M., Reardon, J. T., & Sancar, A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.25.16030 · Cited by 160 · see citing works

TFIIH: a key component in multiple DNA transactions

Hoeijmakers, J. H. J., Egly, J., & Vermeulen, W. (1996) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(96)90006-4 · Cited by 160 · see citing works

Three Unusual Repair Deficiencies Associated with Transcription Factor BTF2(TFIIH): Evidence for the Existence of a Transcription SyndromePreprint

Vermeulen, W., van Vuuren, A. J., Chipoulet, M., Schaeffer, L., Appeldoorn, E., Weeda, G., Jaspers, N. G. J., Priestley, A., Arlett, C. F., Lehmann, A. R., et al. (1994) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1994.059.01.036 · Cited by 143 · see citing works

The multiple roles of transcription/repair factor TFIIH

Svejstrup, J. (1996) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(96)10046-3 · Cited by 136 · see citing works

Clinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3.

Vermeulen, W., Scott, R. J., Rodgers, S., Müller, H., Cole, J., Arlett, C. F., Kleijer, W. J., Bootsma, D., Hoeijmakers, J. H. J., & Weeda, G. (1994) · PubMed Central · Cited by 129 · see citing works

Single-Stranded-DNA Binding Alters Human Replication Protein A Structure and Facilitates Interaction with DNA-Dependent Protein Kinase

Blackwell, L. J., Borowiec, J. A., & Mastrangelo, I. A. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.9.4798 · Cited by 122 · see citing works

RAD25 (SSL2), the yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability.

Park, E., Guzder, S. N., Koken, M. H. M., Jaspers-Dekker, I., Weeda, G., Hoeijmakers, J. H. J., Prakash, S., & Prakash, L. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.23.11416 · Cited by 117 · see citing works

Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH).

van Vuuren, A. J., Vermeulen, W., Ma, L., Weeda, G., Appeldoorn, E., Jaspers, N. G. J., van der Eb, A. J., Bootsma, D., Hoeijmakers, J. H. J., & Humbert, S. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06428.x · Cited by 113 · see citing works

Model for XPC-independent Transcription-coupled Repair of Pyrimidine Dimers in Humans

Mu, D., & Sancar, A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.12.7570 · Cited by 106 · see citing works

DNA unwinding activity of replication protein A

Georgaki, A., Strack, B., Podust, V. N., & Hübscher, U. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)81283-r · Cited by 99 · see citing works

Binding of human single-stranded DNA binding protein to DNA damaged by the anticancer drug cis-diamminedichloroplatinum (II).

Clugston, C. K., McLaughlin, K., Kenny, M. K., & Brown, R. E. (1992) · PubMed · Cited by 90 · see citing works

A 3′→ 5′ XPB Helicase Defect in Repair/Transcription Factor TFIIH of Xeroderma Pigmentosum Group B Affects Both DNA Repair and Transcription

Hwang, J. R., Moncollin, V., Vermeulen, W., Seroz, T., van Vuuren, H., Hoeijmakers, J. H. J., & Egly, J. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.27.15898 · Cited by 89 · see citing works

Detection and Measurement of Nucleotide Excision Repair Synthesis by Mammalian Cell Extracts in Vitro

Wood, R. D., Biggerstaff, M., & Shivji, M. K. K. (1995) · Methods · doi:10.1006/meth.1995.1022 · Cited by 81 · see citing works

A Role for ATP and TFIIH in Activation of the RNA Polymerase II Preinitiation Complex Prior to Transcription Initiation

Dvir, A., Garrett, K. P., Chalut, C., Egly, J., Conaway, J. W., & Conaway, R. C. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.13.7245 · Cited by 81 · see citing works

Detection of Nucleotide Excision Repair Incisions in Human Fibroblasts by Immunostaining for PCNA

Aboussekhra, A., & Wood, R. D. (1995) · Experimental Cell Research · doi:10.1006/excr.1995.1382 · Cited by 78 · see citing works

Reconstitution of TFIIH and Requirement of Its DNA Helicase Subunits, Rad3 and Rad25, in the Incision Step of Nucleotide Excision Repair

Sung, P., Guzder, S. N., Prakash, L., & Prakash, S. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.18.10821 · Cited by 69 · see citing works

Distortions induced in double-stranded oligonucleotides by the binding of cis- or trans-diammine-dichloroplatinum(ll) to the d(GTG) sequence

Anin, M. F., & Leng, M. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.15.4395 · Cited by 65 · see citing works

Inhibition of Rad3 DNA helicase activity by DNA adducts and abasic sites: implications for the role of a DNA helicase in damage-specific incision of DNA

Naegeli, H., Bardwell, L., & Friedberg, E. C. (1993) · Biochemistry · doi:10.1021/bi00053a029 · Cited by 64 · see citing works

Mutations that disable the DNA repair gene XPG in a xeroderma pigmentosum group G patient

Nouspikel, T., & Clarkson, S. G. (1994) · Human Molecular Genetics · doi:10.1093/hmg/3.6.963 · Cited by 62 · see citing works

Enhancement of Damage-Specific DNA Binding of XPA by Interaction with the ERCC1 DNA Repair Protein

Nagai, A., Saijo, M., Kuraoka, I., Matsuda, T., Kodo, N., Nakatsu, Y., Mimaki, T., Mino, M., Biggerstaff, M., Wood, R. D., et al. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.1905 · Cited by 61 · see citing works

DNA Repair and Ultraviolet Mutagenesis in Cells From a New Patient With Xeroderma Pigmentosum Group G and Cockayne Syndrome Resemble Xeroderma Pigmentosum Cells

Moriwaki, S., Stafanim, M., Lehmann, A. R., Hoeijmakers, J. H. J., Robbins, J. H., Rapin, I., Botta, E., Tanganelli, B., Vermeulen, W., Broughton, B. C., et al. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12584287 · Cited by 61 · see citing works

The Solution Structure of a DNA Duplex Containing the cis ‐Pt(NH 3 ) 2 [d(‐GTG‐)‐ N 7(G), N 7(G)] Adduct, as Determined with High‐Field NMR and Molecular Mechanics/Dynamics

Garderen, C. J. V., & Houte, L. P. A. V. (1994) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1994.1169b.x · Cited by 58 · see citing works

The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair.

Sweder, K., & Hanawalt, P. C. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42105-3 · Cited by 57 · see citing works

Mutational Analysis of ERCC3, Which Is Involved in DNA Repair and Transcription Initiation: Identification of Domains Essential for the DNA Repair Function

Ma, L., Westbroek, A., Jochemsen, A. G., Weeda, G., Bosch, A. M., Bootsma, D., Hoeijmakers, J. H. J., & van der Eb, A. J. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.6.4126-4134.1994 · Cited by 51 · see citing works

A low content of ERCC1 and a 120 kDa protein is a frequent feature of group F xeroderma pigmentosum fibroblast cells

Yagi, T., Wood, R. D., & Takebe, H. (1997) · Mutagenesis · doi:10.1093/mutage/12.1.41 · Cited by 47 · see citing works

Nucleotide Requirements for Activated RNA Polymerase II Open Complex Formation in Vitro

Jiang, Y., & Gralla, J. D. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.3.1277 · Cited by 38 · see citing works

The xeroderma pigmentosum group B protein ERCC3 produced in the baculovirus system exhibits DNA helicase activity

Ma, L., Siemssen, E. D., Noteborn, M. H. M., & van der Eb, A. J. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.20.4095 · Cited by 37 · see citing works

Reaction Mechanism of Human DNA Repair Excision Nuclease

Hsu, D. S., Sancar, A., & Mu, D. (2021) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/adqz-gn74 · Cited by 33 · see citing works

The General Transcription-Repair Factor TFIIH Is Recruited to the Excision Repair Complex by the XPA Protein Independent of the TFIIE Transcription Factor

Reardon, J. T., Park, C. H., Sancar, A., et al. (2021) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/neqj-kk06 · Cited by 17 · see citing works

Model for XPC-independent Transcription-coupled Repair of Pyrimidine Dimers in Humans

Sancar, A., & Mu, D. (2021) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/52fb-tv35 · Cited by 8 · see citing works

Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints

Sancar, A., Lindsey-Boltz, L. A., Ünsal-Kaçmaz, K., & Linn, S. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073723 · Cited by 3,317 · see citing works

Molecular Mechanisms of Ultraviolet Radiation‐Induced DNA Damage and Repair

Rastogi, R. P., Richa, Kumar, A., Tyagi, M. B., & Sinha, R. P. (2010) · Journal of Nucleic Acids · doi:10.4061/2010/592980 · Cited by 1,329 · see citing works

Molecular mechanism of nucleotide excision repair

de Laat, W. L., Jaspers, N. G. J., & Hoeijmakers, J. H. J. (1999) · Genes & Development · doi:10.1101/gad.13.7.768 · Cited by 1,122 · see citing works

Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair

Sugasawa, K., Ng, J. M. Y., Masutani, C., Iwai, S., van der Spek, P. J., Eker, A. P. M., Hanaoka, F., Bootsma, D., & Hoeijmakers, J. H. J. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80132-x · Cited by 899 · see citing works

Nucleotide Excision Repair in EukaryotesPreprint

Schärer, O. D. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a012609 · Cited by 801 · see citing works

Sequential Assembly of the Nucleotide Excision Repair Factors In Vivo

Volker, M., Moné, M. J., Karmakar, P., van Hoffen, A., Schul, W., Vermeulen, W., Hoeijmakers, J. H. J., DRIEL, R. V., van Zeeland, A. A., & Mullenders, L. H. F. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00281-7 · Cited by 782 · see citing works

DNA repair mechanisms in dividing and non-dividing cells

Iyama, T., & Wilson, D. M. (2013) · DNA Repair · doi:10.1016/j.dnarep.2013.04.015 · Cited by 697 · see citing works

Nucleotide excision repair and human syndromes

de Boer, J., & Hoeijmakers, J. H. J. (2000) · Carcinogenesis · doi:10.1093/carcin/21.3.453 · Cited by 674 · see citing works

Molecular Mechanisms of Mammalian Global Genome Nucleotide Excision Repair

Gillet, L. C. J., & Schärer, O. D. (2006) · Chemical Reviews · doi:10.1021/cr040483f · Cited by 642 · see citing works

Mechanisms of human DNA repair: an update

Christmann, M., Tomicic, M. T., Roos, W. P., & Kaina, B. (2003) · Toxicology · doi:10.1016/s0300-483x(03)00287-7 · Cited by 578 · see citing works

Molecular Interaction Map of the Mammalian Cell Cycle Control and DNA Repair Systems

Kohn, K. W. (1999) · Molecular Biology of the Cell · doi:10.1091/mbc.10.8.2703 · Cited by 550 · see citing works

Premature Aging in Mice Deficient in DNA Repair and Transcription

de Boer, J., Andressoo, J. O., de Wit, J., Huijmans, J., Beems, R. B., van Steeg, H., Weeda, G., van der Horst, G. T. J., van Leeuwen, W., Themmen, A. P. N., et al. (2002) · Science · doi:10.1126/science.1070174 · Cited by 545 · see citing works

Mus81-Eme1 Are Essential Components of a Holliday Junction Resolvase

Boddy, M. N., Gaillard, P.-H. L., McDonald, W. H., Shanahan, P., Yates, J. R., & Russell, P. R. (2001) · Cell · doi:10.1016/s0092-8674(01)00536-0 · Cited by 545 · see citing works

Replication Protein A (RPA): The Eukaryotic SSB

Iftode, C., Daniely, Y., & Borowiec, J. A. (1999) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409239991209255 · Cited by 472 · see citing works

A multistep damage recognition mechanism for global genomic nucleotide excision repair

Sugasawa, K., Okamoto, T., Shimizu, Y., Masutani, C., Iwai, S., & Hanaoka, F. (2001) · Genes & Development · doi:10.1101/gad.866301 · Cited by 435 · see citing works

The comings and goings of nucleotide excision repair factors on damaged DNA

Riedl, T., Hanaoka, F., & Egly, J. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg489 · Cited by 439 · see citing works

Closing the gaps among a web of DNA repair disorders

Michelson, R. J., & Weinert, T. A. (2000) · BioEssays · doi:10.1002/1521-1878(200011)22:11 · Cited by 61 · see citing works

DNA repair mechanisms in cancer development and therapy

Torgovnick, A., & Schumacher, B. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00157 · Cited by 403 · see citing works

Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity

Cleaver, J. E., Lam, E. T., & Revet, I. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2663 · Cited by 428 · see citing works

Chemistry and Biology of DNA Repair

Schärer, O. D. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200200523 · Cited by 381 · see citing works

The eukaryotic nucleotide excision repair pathway

Costa, R. (2003) · Biochimie · doi:10.1016/j.biochi.2003.10.017 · Cited by 373 · see citing works

Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance

McHugh, P. J., Spanswick, V. J., & Hartley, J. A. (2001) · The Lancet Oncology · doi:10.1016/s1470-2045(01)00454-5 · Cited by 378 · see citing works

The xeroderma pigmentosum group D (XPD) gene: one gene, two functions, three diseasesPreprint

Lehmann, A. R. (2001) · Genes & Development · doi:10.1101/gad.859501 · Cited by 370 · see citing works

Nucleotide Excision Repair

Reardon, J. T., & Sancar, A. (2005) · Progress in Nucleic Acid Research and Molecular Biology · doi:10.1016/s0079-6603(04)79004-2 · Cited by 350 · see citing works

Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH

Coin, F., Marinoni, J., Rodolfo, C., Fribourg, S., Pedrini, A. M., & Egly, J. (1998) · Nature Genetics · doi:10.1038/2491 · Cited by 350 · see citing works

Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair

Takebayashi, Y., Pourquier, P., Zimonjic, D. B., Nakayama, K., Emmert, S., Ueda, T., Urasaki, Y., Kanzaki, A., Akiyama, S., Popescu, N. C., et al. (2001) · Nature Medicine · doi:10.1038/91008 · Cited by 348 · see citing works

Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAKPreprint

Araújo, S. J., Tirode, F., Coin, F., Pospiech, H., Syväoja, J. E., Stucki, M., Hübscher, U., Egly, J., & Wood, R. D. (2000) · Genes & Development · doi:10.1101/gad.14.3.349 · Cited by 334 · see citing works

DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repairPreprint

de Laat, W. L., Appeldoorn, E., Sugasawa, K., Weterings, E., Jaspers, N. G. J., & Hoeijmakers, J. H. J. (1998) · Genes & Development · doi:10.1101/gad.12.16.2598 · Cited by 333 · see citing works

TFIIH: when transcription met DNA repair

Compe, E., & Egly, J. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3350 · Cited by 333 · see citing works

Defective repair of cisplatin-induced DNA damage caused by reduced XPA protein in testicular germ cell tumours

Köberle, B., Masters, J. R., Hartley, J. A., & Wood, R. D. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80118-3 · Cited by 298 · see citing works

Damage recognition in nucleotide excision repair of DNA

Batty, D. P., & Wood, R. D. (2000) · Gene · doi:10.1016/s0378-1119(99)00489-8 · Cited by 296 · see citing works

Distinct Roles for the XPB/p52 and XPD/p44 Subcomplexes of TFIIH in Damaged DNA Opening during Nucleotide Excision Repair

Coin, F., Oksenych, V., & Egly, J. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.03.009 · Cited by 294 · see citing works

TP53 mutations in human skin cancers

Giglia‐Mari, G., & Sarasin, A. R. (2003) · Human Mutation · doi:10.1002/humu.10179 · Cited by 293 · see citing works

Base Excision Repair of Oxidative DNA Damage Activated by XPG Protein

Klungland, A., Höss, M., Gunz, D., Constantinou, A., Clarkson, S. G., Doetsch, P. W., Bolton, P. H., Wood, R. D., & Lindahl, T. L. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80172-0 · Cited by 291 · see citing works

Coordination of dual incision and repair synthesis in human nucleotide excision repair

Staresincic, L., Fagbemi, A. F., Enzlin, J. H., Gourdin, A. M., Wijgers, N., Dunand‐Sauthier, I., Giglia‐Mari, G., Clarkson, S. G., Vermeulen, W., & Schärer, O. D. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.49 · Cited by 287 · see citing works

Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology

Shuck, S. C., Short, E. A., & Turchi, J. J. (2008) · Cell Research · doi:10.1038/cr.2008.2 · Cited by 279 · see citing works

The Xeroderma Pigmentosum Group C Protein Complex XPC-HR23B Plays an Important Role in the Recruitment of Transcription Factor IIH to Damaged DNA

Yokoi, M., Masutani, C., Maekawa, T., Sugasawa, K., Ohkuma, Y., & Hanaoka, F. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.13.9870 · Cited by 277 · see citing works

Increased nucleotide excision repair in cisplatin-resistant ovarian cancer cells

Ferry, K. V., Hamilton, T. C., & Johnson, S. W. (2000) · Biochemical Pharmacology · doi:10.1016/s0006-2952(00)00441-x · Cited by 275 · see citing works

Molecular Mechanisms of DNA Damage and Repair: Progress in Plants

Tuteja, N., Singh, M. B., Misra, M. K., Bhalla, P. L., & Tuteja, R. (2001) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/20014091074219 · Cited by 272 · see citing works

Light and dark in chromatin repair: repair of UV‐induced DNA lesions by photolyase and nucleotide excision repair

Thoma, F. (1999) · The EMBO Journal · doi:10.1093/emboj/18.23.6585 · Cited by 271 · see citing works

DNA damage recognition during nucleotide excision repair in mammalian cells

Wood, R. D. (1999) · Biochimie · doi:10.1016/s0300-9084(99)80036-4 · Cited by 264 · see citing works

Genotoxic stress in plants: Shedding light on DNA damage, repair and DNA repair helicases

Tuteja, N. K., Ahmad, P., Panda, B. B., & Tuteja, R. (2008) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2008.06.004 · Cited by 255 · see citing works

DNA Helicases, Genomic Instability, and Human Genetic Disease

van Brabant, A. J., Stan, R., & Ellis, N. A. (2000) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.1.1.409 · Cited by 252 · see citing works

Centrin 2 Stimulates Nucleotide Excision Repair by Interacting with Xeroderma Pigmentosum Group C Protein

Nishi, R., Okuda, Y., Watanabe, E., Mori, T., Iwai, S., Masutani, C., Sugasawa, K., & Hanaoka, F. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.13.5664-5674.2005 · Cited by 249 · see citing works

DNA Repair Mechanisms and the Bypass of DNA Damage in Saccharomyces cerevisiae

Boiteux, S., & Jinks-Robertson, S. (2013) · Genetics · doi:10.1534/genetics.112.145219 · Cited by 227 · see citing works

Recognition of RNA Polymerase II and Transcription Bubbles by XPG, CSB, and TFIIH: Insights for Transcription-Coupled Repair and Cockayne Syndrome

Sarker, A. H., Tsutakawa, S. E., Kostek, S. A., Ng, C., Shin, D. S., Peris, M., Campeau, E., Tainer, J. A., Nogales, E., & Cooper, P. K. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.09.022 · Cited by 224 · see citing works

Crystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPD

Wolski, S. C., Kuper, J., Hänzelmann, P., Truglio, J. J., Croteau, D. L., Houten, B. V., & Kisker, C. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060149 · Cited by 218 · see citing works

The current state of eukaryotic DNA base damage and repair

Bauer, N. C., Corbett, A. H., & Doetsch, P. W. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv1136 · Cited by 216 · see citing works

First Reported Patient with Human ERCC1 Deficiency Has Cerebro-Oculo-Facio-Skeletal Syndrome with a Mild Defect in Nucleotide Excision Repair and Severe Developmental Failure

Jaspers, N. G. J., Raams, A., Silengo, M., Wijgers, N., Niedernhofer, L. J., Robinson, A. R., Giglia‐Mari, G., Hoogstraten, D., Kleijer, W. J., Hoeijmakers, J. H. J., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/512486 · Cited by 213 · see citing works

Xeroderma pigmentosum and the role of UV-induced DNA damage in skin cancer

STEEG, H. V., & Kraemer, K. H. (1999) · Molecular Medicine Today · doi:10.1016/s1357-4310(98)01394-x · Cited by 211 · see citing works

Stable binding of human XPC complex to irradiated DNA confers strong discrimination for damaged sites 1 1Edited by M. Yaniv

Batty, D. P., Rapić-Otrin, V., Levine, A. S., & Wood, R. D. (2000) · Journal of Molecular Biology · doi:10.1006/jmbi.2000.3857 · Cited by 208 · see citing works

3 Xeroderma pigmentosum and related disorders: Defects in DNA repair and transcription

Berneburgl, M., & Lehmann, A. R. (2001) · Advances in genetics · doi:10.1016/s0065-2660(01)43004-5 · Cited by 200 · see citing works

XPG Stabilizes TFIIH, Allowing Transactivation of Nuclear Receptors: Implications for Cockayne Syndrome in XP-G/CS Patients

Ito, S., Kuraoka, I., Chymkowitch, P., Compe, E., Takedachi, A., Ishigami, C., Coin, F., Egly, J., & Tanaka, K. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.03.013 · Cited by 194 · see citing works

The active site of the DNA repair endonuclease XPF–ERCC1 forms a highly conserved nuclease motif

Enzlin, J. H., & Schärer, O. D. (2002) · The EMBO Journal · doi:10.1093/emboj/21.8.2045 · Cited by 196 · see citing works

A Mouse Model for the Basal Transcription/DNA Repair Syndrome Trichothiodystrophy

de Boer, J., de Wit, J., STEEG, H. V., Berg, R. J. W., Morreau, H., Visser, P., Lehmann, A. R., Durán, M., Hoeijmakers, J. H. J., & Weeda, G. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80098-2 · Cited by 195 · see citing works

Mutations in XPB and XPD helicases found in xeroderma pigmentosum patients impair the transcription function of TFIIH

Coin, F., Bergmann, E., Tremeau‐Bravard, A., & Egly, J. (1999) · The EMBO Journal · doi:10.1093/emboj/18.5.1357 · Cited by 195 · see citing works

Double‐check probing of DNA bending and unwinding by XPA–RPA: an architectural function in DNA repair

Missura, M., Buterin, T., Hindges, R., Hübscher, U., Kašpárková, J., Brabec, V., & Naegeli, H. (2001) · The EMBO Journal · doi:10.1093/emboj/20.13.3554 · Cited by 195 · see citing works

Rapid Switching of TFIIH between RNA Polymerase I and II Transcription and DNA Repair In Vivo

Hoogstraten, D., Nigg, A. L., Heath, H., Mullenders, L. H. F., DRIEL, R. V., Hoeijmakers, J. H. J., Vermeulen, W., & Houtsmuller, A. B. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00709-8 · Cited by 191 · see citing works

XPD Mutations Prevent TFIIH-Dependent Transactivation by Nuclear Receptors and Phosphorylation of RARα

Keriel, A., Stary, A., Sarasin, A., Rochette-Egly, C., & Egly, J.-M. (2002) · Cell · doi:10.1016/s0092-8674(02)00692-x · Cited by 192 · see citing works

Unraveling DNA helicases

Tuteja, N. K., & Tuteja, R. (2004) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.2004.04094.x · Cited by 191 · see citing works

A molecular mechanism for DNA damage recognition by the xeroderma pigmentosum group C protein complex

Sugasawa, K., Shimizu, Y., Iwai, S., & Hanaoka, F. (2002) · DNA repair · doi:10.1016/s1568-7864(01)00008-8 · Cited by 186 · see citing works

Replication protein A: directing traffic at the intersection of replication and repair

Oakley, G. G. (2010) · Frontiers in bioscience · doi:10.2741/3652 · Cited by 180 · see citing works

The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II

van der Weegen, Y., Golan-Berman, H., Mevissen, T. E. T., Apelt, K., González‐Prieto, R., Goedhart, J., Heilbrun, E. E., Vertegaal, A. C. O., van den Heuvel, D., Walter, J. C., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-15903-8 · Cited by 177 · see citing works

DNA Damage in the Nucleosome Core Is Refractory to Repair by Human Excision Nuclease

Hara, R., Mo, J., & Sancar, A. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.24.9173-9181.2000 · Cited by 184 · see citing works

The Endogenous Mus81-Eme1 Complex Resolves Holliday Junctions by a Nick and Counternick Mechanism

Gaillard, P.-H. L., Noguchi, E., Shanahan, P., & Russell, P. R. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00342-3 · Cited by 181 · see citing works

TFIIH with Inactive XPD Helicase Functions in Transcription Initiation but Is Defective in DNA Repair

Winkler, G. S., Araújo, S. J., Fiedler, U., Vermeulen, W., Coin, F., Egly, J., Hoeijmakers, J. H. J., Wood, R. D., Timmers, H. T. M., & Weeda, G. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.6.4258 · Cited by 181 · see citing works

Molecular Structure of Human TFIIH

Schultz, P., Fribourg, S., Poterszman, A., Mallouh, V., Moras, D., & Egly, J. M. (2000) · Cell · doi:10.1016/s0092-8674(00)00082-9 · Cited by 180 · see citing works

Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease

Reardon, J. T., & Sancar, A. (2003) · Genes & Development · doi:10.1101/gad.1131003 · Cited by 179 · see citing works

Strong Functional Interactions of TFIIH with XPC and XPG in Human DNA Nucleotide Excision Repair, without a Preassembled Repairosome

Araújo, S. J., Nigg, E. A., & Wood, R. D. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.7.2281-2291.2001 · Cited by 178 · see citing works

Regulation of endonuclease activity in human nucleotide excision repair

Fagbemi, A. F., Orelli, B., & Schärer, O. D. (2011) · DNA repair · doi:10.1016/j.dnarep.2011.04.022 · Cited by 173 · see citing works

XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase

Fuss, J. O., & Tainer, J. A. (2011) · DNA Repair · doi:10.1016/j.dnarep.2011.04.028 · Cited by 170 · see citing works

Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step

Mocquet, V., Lainé, J., Riedl, T., Yajin, Z., Lee, M. Y., & Egly, J. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601948 · Cited by 164 · see citing works

Genetic variability in susceptibility and response to toxicants

Miller, M. C., Mohrenweiser, H. W., & Bell, D. A. (2001) · Toxicology Letters · doi:10.1016/s0378-4274(01)00279-x · Cited by 164 · see citing works

Structural basis of TFIIH activation for nucleotide excision repair

Kokic, G., Chernev, A., Tegunov, D., Dienemann, C., Urlaub, H., & Cramer, P. (2019) · Nature Communications · doi:10.1038/s41467-019-10745-5 · Cited by 163 · see citing works

Growth Retardation, Early Death, and DNA Repair Defects in Mice Deficient for the Nucleotide Excision Repair Enzyme XPF

Tian, M., Shinkura, R., Shinkura, N., & Alt, F. W. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.3.1200-1205.2004 · Cited by 159 · see citing works

Human DNA repair genes

Ronen, A., & Glickman, B. W. (2001) · Environmental and Molecular Mutagenesis · doi:10.1002/em.1033 · Cited by 158 · see citing works

Ordered Conformational Changes in Damaged DNA Induced by Nucleotide Excision Repair Factors

Tapias, A., Auriol, J., Forget, D., Enzlin, J. H., Schärer, O. D., Coin, F., Coulombe, B., & Egly, J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312611200 · Cited by 156 · see citing works

Nucleotide Excision Repair and Transcriptional Regulation: TFIIH and Beyond

Compe, E., & Egly, J. (2016) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060815-014857 · Cited by 156 · see citing works

Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesions

Rademakers, S., Volker, M., Hoogstraten, D., Nigg, A. L., Moné, M. J., van Zeeland, A. A., Hoeijmakers, J. H. J., Houtsmuller, A. B., & Vermeulen, W. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.16.5755-5767.2003 · Cited by 149 · see citing works

The SWI/SNF Chromatin-Remodeling Factor Stimulates Repair by Human Excision Nuclease in the Mononucleosome Core Particle

Hara, R., & Sancar, A. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.19.6779-6787.2002 · Cited by 143 · see citing works

The changing faces of HP1: From heterochromatin formation and gene silencing to euchromatic gene expression

Kwon, S. H., & Workman, J. L. (2011) · BioEssays · doi:10.1002/bies.201000138 · Cited by 138 · see citing works

The ERCC1 and ERCC4 (XPF) genes and gene products

Manandhar, M., Boulware, K. S., & Wood, R. D. (2015) · Gene · doi:10.1016/j.gene.2015.06.026 · Cited by 139 · see citing works

Mammalian nucleotide excision repair proteins and interstrand crosslink repair

Wood, R. D. (2010) · Environmental and Molecular Mutagenesis · doi:10.1002/em.20569 · Cited by 134 · see citing works

DNA Repair Gene XRCC1 and XPD Polymorphisms and Risk of Prostate Cancer

Rybicki, B. A., Conti, D. V., Moreira, A. A., Cicek, M. S., Casey, G., & Witte, J. S. (2004) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-03-0053 · Cited by 132 · see citing works

Who's on first in the cellular response to DNA damage?

Cline, S. D., & Hanawalt, P. C. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1101 · Cited by 129 · see citing works

Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocation

Kuper, J., Wolski, S. C., Michels, G., & Kisker, C. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.374 · Cited by 129 · see citing works

Translocation of Cockayne syndrome group A protein to the nuclear matrix: Possible relevance to transcription-coupled DNA repair

Kamiuchi, S., Saijo, M., Citterio, E., de Jager, M., Hoeijmakers, J. H. J., & Tanaka, K. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.012473199 · Cited by 129 · see citing works

Chromatin structure and DNA damage repair

Dinant, C., Houtsmuller, A. B., & Vermeulen, W. (2008) · Epigenetics & Chromatin · doi:10.1186/1756-8935-1-9 · Cited by 122 · see citing works

Role of ERCC1 in removal of long non‐homologous tails during targeted homologous recombination

Adair, G. M., Rolig, R. L., Moore‐Faver, D., Zabelshansky, M., Wilson, J. H., & Nairn, R. S. (2000) · The EMBO Journal · doi:10.1093/emboj/19.20.5552 · Cited by 125 · see citing works

TFIIH: from transcription to clinic

Egly, J. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02458-9 · Cited by 123 · see citing works

Critical DNA damage recognition functions of XPC‐hHR23B and XPA‐RPA in nucleotide excision repair

Thoma, B. S., & Vasquez, K. M. (2003) · Molecular Carcinogenesis · doi:10.1002/mc.10143 · Cited by 122 · see citing works

Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair

Luijsterburg, M. S., von Bornstaedt, G., Gourdin, A. M., Politi, A. Z., Moné, M. J., Warmerdam, D. O., Goedhart, J., Vermeulen, W., van Driel, R., & Höfer, T. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200909175 · Cited by 121 · see citing works

Defects in interstrand cross-link uncoupling do not account for the extreme sensitivity of ERCC1 and XPF cells to cisplatin

Silva, I. U. D. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf479 · Cited by 122 · see citing works

The Emerging Role of HP1 in the DNA Damage Response

Dinant, C., & Luijsterburg, M. S. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01048-09 · Cited by 122 · see citing works

Mapping of interaction domains between human repair proteins ERCC1 and XPF

de Laat, W. L. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.18.4146 · Cited by 121 · see citing works

The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways

Orelli, B., McClendon, T. B., Tsodikov, O. V., Ellenberger, T., Niedernhofer, L. J., & Schärer, O. D. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.067538 · Cited by 116 · see citing works

Conserved Residues of Human XPG Protein Important for Nuclease Activity and Function in Nucleotide Excision Repair

Constantinou, A., Gunz, D., Evans, E., Lalle, P., Bates, P. A., Wood, R. D., & Clarkson, S. G. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.9.5637 · Cited by 119 · see citing works

Mechanisms of DNA damage recognition and strand discrimination in human nucleotide excision repair

Dip, R., Camenisch, U., & Naegeli, H. (2004) · DNA repair · doi:10.1016/j.dnarep.2004.05.005 · Cited by 116 · see citing works

The complete structure of the human TFIIH core complex

Greber, B. J., Toso, D. B., Fang, J., & Nogales, E. (2019) · eLife · doi:10.7554/elife.44771 · Cited by 117 · see citing works

Human single-stranded DNA binding proteins are essential for maintaining genomic stability

Ashton, N. W., Bolderson, E., Cubeddu, L., O'Byrne, K. J., & Richard, D. J. (2013) · BMC Molecular Biology · doi:10.1186/1471-2199-14-9 · Cited by 113 · see citing works

Distinct Roles for the XPB/p52 and XPD/p44 Subcomplexes of TFIIH in Damaged DNA Opening during Nucleotide Excision Repair

Coin, F., Oksenych, V., & Egly, J. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.03.009 · Cited by 294 · see citing works

Reaction Mechanism of Human DNA Repair Excision Nuclease

Mu, D., Hsu, D. S., & Sancar, A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.14.8285 · Cited by 374 · see citing works

Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein

Evans, E. L., Fellows, J., Coffer, A. I., & Wood, R. D. (1997) · The EMBO Journal · doi:10.1093/emboj/16.3.625 · Cited by 237 · see citing works

Molecular Mechanisms of DNA Opening by XPB Helicase and its Interaction With Nuclease in Nucleotide Excision Repair

He, F. (2021) · eScholarship (California Digital Library)

Pre-incision structures reveal principles of DNA nucleotide excision repair

Li, E. C. L., Kim, J., Brussee, S. J., Sugasawa, K., Luijsterburg, M. S., & Yang, W. (2026) · Nature · doi:10.1038/s41586-026-10122-5 · Cited by 10 · see citing works