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The Relation between Work-related Psychosocial Factors and the Development of Depression

Netterstrom, B., Conrad, N., Bech, P., Fink, P., Olsen, O., Rugulies, R., Stansfeld, S.·2008·Epidemiologic Reviews

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Abstract

This review is based on a literature search made in January 2007 on request by the Danish National Board of Industrial Injuries. The search in PubMed, EMBASE, and PsycINFO resulted in more than 1,000 publications. This was reduced to 14 after the titles, abstracts, and papers were evaluated by using the following criteria: 1) a longitudinal study, 2) exposure to work-related psychosocial factors, 3) the outcome a measure of depression, 4) relevant statistical estimates, and 5) nonduplicated publication. Of the 14 studies, seven used standardized diagnostic instruments as measures of depression, whereas the other seven studies used self-administered questionnaires. The authors found moderate evidence for a relation between the psychological demands of the job and the development of depression, with relative risks of approximately 2.0. However, indication of publication bias weakens the evidence. Social support at work was associated with a decrease in risk for future depression, as all four studies dealing with this exposure showed associations with relative risks of about 0.6. Even if this literature study has identified work-related psychosocial factors that in high-quality epidemiologic studies predict depression, studies are still needed that assess in more detail the duration and intensity of exposure necessary for developing depression.

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Authors: Netterstrom, B., Conrad, N., Bech, P., Fink, P., Olsen, O., Rugulies, R., & Stansfeld, S.
Affiliations: Capital Region of Denmark (DK)
Aarhus University Hospital (DK)
National Research Centre for the Working Environment (DK)
Queen Mary University of London (GB)
ORCID: Bech, P.
Fink, P.
Rugulies, R.
Stansfeld, S.
Venue: Epidemiologic Reviews
Publisher: Oxford University Press (OUP)
Published: 2008-05-14
Volume: 30
Issue: 1
Pages: 118-132
ISSN: 0193-936X (ISSN-L)
1478-6729
DOI: 10.1093/epirev/mxn004
OpenAlex: W2148031529
Cited by: 467
References: 114
Citations by year: 2026: 5 · 2025: 12 · 2024: 11 · 2023: 13 · 2022: 14 · 2021: 22 · 2020: 31 · 2019: 26 · 2018: 24 · 2017: 37 · 2016: 30 · 2015: 38 · 2014: 48 · 2013: 43 · 2012: 40
FWCI: 4.54
Type: journal article
Language: en
Open access: closed
Locations: Epidemiologic Reviews (publishedVersion)
PubMed (publishedVersion)
HighWire Press Open Archive (submittedVersion)
Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Workplace Health and Well-being
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational Health and Burnout
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Employment and Welfare Studies
Keywords: depression, psychological job demands, social support at work, workplace mental health, relative risk, publication bias
MeSH terms: Depression, Humans, Psychology, Risk Factors, Severity of Illness Index, Social Support, Work

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The Relation between Work-related Psychosocial Factors and the Development of Depression

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