Behavioural interventions for smoking cessation: a meta-analysis of randomized controlled trials
Abstract
AIMS: Widely varying estimates of treatment effects have been reported in randomized controlled trials (RCTs) investigating the efficacy of behavioural interventions for smoking cessation. Previous meta-analyses investigating behavioural interventions have important limitations and do not include recently published RCTs. We undertook a meta-analysis of RCTs to synthesize the treatment effects of four behavioural interventions, including minimal clinical intervention (brief advice from a healthcare worker), and intensive interventions, including individual, group, and telephone counselling. METHODS AND RESULTS: We searched the CDC Tobacco Information and Prevention, Cochrane Library, EMBASE, Medline, and PsycINFO databases. We included only RCTs that reported biochemically validated smoking cessation outcomes at 6 and/or 12 months after the target quit date. Outcomes were aggregated using hierarchical Bayesian random-effects models. We identified 50 RCTs, which randomized n = 26 927 patients (minimal clinical intervention: 9 RCTs, n = 6456; individual counselling: 23 RCTs, n = 8646; group counselling: 12 RCTs, n = 3600; telephone counselling: 10 RCTs, n = 8225). The estimated mean treatment effects were minimal clinical intervention [odds ratio (OR) 1.50, 95% credible interval (CrI) 0.84-2.78], individual counselling (OR 1.49, 95% CrI 1.08-2.07), group counselling (OR 1.76, 95% CrI 1.11-2.93), and telephone counselling (OR 1.58, 95% CrI 1.15-2.29). CONCLUSION: Intensive behavioural interventions result in substantial increases in smoking abstinence compared with control. Although minimal clinical intervention may increase smoking abstinence, there is insufficient evidence to draw strong conclusions regarding its efficacy.
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In a review of 50 randomised controlled trials and another review of 23 studies since January 2000, a group format for a behavioural intervention was not found to be significantly different from an individual format.
“In a review of 50 randomised controlled trials 22 and another review of 23 studies since January 2000, 23 a group format for a behavioural intervention was not found to be significantly different from an individual format”
From Evaluating Long-term Outcomes of NHS Stop Smoking Services (ELONS): a prospective cohort study (2015) · cites this paper as [22]
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“In a review of 50 RCTs (24) and another review of 23 studies since January 2000 (25) group-based behavioural support was not found to be significantly different to one to one support.”
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Bennett, D., Krishnamurthi, R., Barker-Collo, S. L., Forouzanfar, M. H., Naghavi, M., Connor, M., Lawes, C. M. M., Moran, A. E., Anderson, L. M., Roth, G. A., et al. (2014) · Global Heart · doi:10.1016/j.gheart.2014.01.001 · Cited by 171 · see citing works
“In recent decades, there have been significant reductions in smoking in HIC (such as the United States) due to political interventions (such as smoke-free policies [14], higher taxes, and/or higher prices) [15], smoking cessation programs [16], and clinical guidelines [17].”
BackgroundAn online survey of tobacco smoking cessation associated with naturalistic psychedelic use
Johnson, M. W., Garcia‐Romeu, A., Johnson, P. S., & Griffiths, R. R. (2017) · Journal of Psychopharmacology · doi:10.1177/0269881116684335 · Cited by 129 · see citing works
“However, these success rates substantially exceed those for the most efficacious accepted smoking cessation treatments, typically <35% abstinence rates at 6 months (Cahill et al., 2014; Mottillo et al., 2009).”
BackgroundSensory Imagery in Craving: From Cognitive Psychology to New Treatments for Addiction
Andrade, J., May, J., & Kavanagh, D. (2012) · Journal of Experimental Psychopathology · doi:10.5127/jep.024611 · Cited by 95 · see citing works
“…2002; Tripodi, Bender, Litschge & Vaughn, 2010, in relation to alcohol dependence; Nordstrom & Levin, 2007, in relation to cannabis use disorders; Mottillo et al., 2009 in relation to cigarette smoking), both on their own and combined with pharmacological treatments (e.g., Donovan et al, 2008).”
BackgroundSuissa, K., Larivière, J., Eisenberg, M. J., Eberg, M., Gore, G. C., Grad, R., Joseph, L., Reynier, P. M., & Filion, K. B. (2017) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.115.002458 · Cited by 109 · see citing works
Self-citationBupropion for Smoking Cessation in Patients Hospitalized With Acute Myocardial Infarction
Eisenberg, M. J., Grandi, S. M., Gervais, A., O’Loughlin, J. L., Paradis, G., Rinfret, S., Sarrafzadegan, N., Sharma, S., Lauzon, C., Yadav, R. K., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.08.1030 · Cited by 103 · see citing works
Self-citationSmoking Cessation for People Living With HIV/AIDS: A Literature Review and Synthesis
Ledgerwood, D. M., & Yskes, R. (2016) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntw126 · Cited by 101 · see citing works
Webb, M. S., de Ybarra, D. R., Baker, E. A., Reis, I. M., & Carey, M. P. (2010) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0017669 · Cited by 79 · see citing works
Nieuwkerk, P. T., Nierman, M. C., Vissers, M. N., Locadia, M., Greggers-Peusch, P., Knape, L. P. M., Kastelein, J. J. P., Sprangers, M. A. G., de Haes, J. C. J. M., & Stroes, E. S. G. (2012) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2012.04.045 · Cited by 80 · see citing works
Evaluating Long-term Outcomes of NHS Stop Smoking Services (ELONS): a prospective cohort study
Dobbie, F., Hiscock, R., Leonardi-Bee, J., Murray, S., Shahab, L., Aveyard, P., Coleman, T., McEwen, A., McRobbie, H., Purves, R., et al. (2015) · Health Technology Assessment · doi:10.3310/hta19950 · Cited by 79 · see citing works
Carlson, L. E., Lounsberry, J. J., Maciejewski, O., Wright, K., Collacutt, V., & Taenzer, P. A. (2011) · Addictive Behaviors · doi:10.1016/j.addbeh.2011.09.011 · Cited by 79 · see citing works
“Randomized controlled trials of various smoking cessation interventions for healthy populations demonstrate quit rates ranging from 2 to 34% for individual counseling, 5–39% for group interventions, and 2–30% for telephone based interventions (Mottillo et al., 2009).”
BackgroundPsychosoziales und Diabetes (Teil 1)
Kulzer, B., Albus, C., Herpertz, S., Kruse, J., Lange, K., Lederbogen, F., & Petrak, F. (2013) · Diabetologie und Stoffwechsel · doi:10.1055/s-0033-1335785 · Cited by 62 · see citing works
Gold Standard Program for Heavy Smokers in a Real-Life Setting
Neumann, T., Rasmussen, M., Heitmann, B. L., & Tønnesen, H. (2013) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph10094186 · Cited by 73 · see citing works
“Previously, group format and one-on-one settings were equally effective in achieving abstinence [18,19,31–33].”
BackgroundValidation of smoking-related virtual environments for cue exposure therapy
García–Rodríguez, O., Pericot‐Valverde, I., Gutiérrez‐Maldonado, J., Ferrer‐García, M., & Secades‐Villa, R. (2012) · Addictive Behaviors · doi:10.1016/j.addbeh.2012.02.013 · Cited by 69 · see citing works
Yun, E. H., Kang, Y. H., Lim, M. K., Oh, J., & Son, J. M. (2010) · BMC Public Health · doi:10.1186/1471-2458-10-78 · Cited by 65 · see citing works
Effectiveness of nonpharmacological secondary prevention of coronary heart disease
Müller-Riemenschneider, F., Meinhard, C., Damm, K., Vauth, C., Bockelbrink, A., Greiner, W., & Willich, S. N. (2010) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e32833a1c95 · Cited by 57 · see citing works
Psychosoziales und Diabetes (Teil 2)
Kulzer, B., Albus, C., Herpertz, S., Kruse, J., Lange, K., Lederbogen, F., & Petrak, F. (2013) · Diabetologie und Stoffwechsel · doi:10.1055/s-0033-1335889 · Cited by 24 · see citing works
Comparison of Available Treatments for Tobacco Addiction
Herman, A. I., & Sofuoglu, M. (2010) · Current Psychiatry Reports · doi:10.1007/s11920-010-0134-6 · Cited by 53 · see citing works
“A recent meta-analysis of 50 randomized behavioral treatments for smoking cessation concluded that telephone counseling, group treatment, and individual treatments all seem to increase the chances of quitting smoking [ 10 ].”
BackgroundMerriel, S. W. D., Andrews, V., & Salisbury, C. (2014) · Preventive Medicine · doi:10.1016/j.ypmed.2014.04.001 · Cited by 51 · see citing works
Filion, K. B., Abenhaim, H., Mottillo, S., Joseph, L., Gervais, A., O’Loughlin, J. L., Paradis, G., Pihl, R. O., Pilote, L., Rinfret, S., et al. (2011) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2011.03065.x · Cited by 51 · see citing works
Self-citationYaden, D. B., Berghella, A. P., Regier, P. S., Garcia‐Romeu, A., Johnson, M. W., & Hendricks, P. S. (2021) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2021.103380 · Cited by 50 · see citing works
Andreu, C. I., Cosmelli, D., Slagter, H. A., & Franken, I. H. A. (2018) · PLOS ONE · doi:10.1371/journal.pone.0191661 · Cited by 47 · see citing works
“Although smokers realize that smoking carries health risks, quitting smoking is notoriously hard and may require several attempts [3].”
BackgroundCombination Therapies for Smoking Cessation
Windle, S. B., Filion, K. B., Mancini, J. G., Adye-White, L., Joseph, L., Gore, G. C., Habib, B., Grad, R., Pilote, L., & Eisenberg, M. J. (2016) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2016.07.011 · Cited by 46 · see citing works
“Although the inclusion of minimal clinical interventions with more intensive BTs may, in theory, dilute treatment effects, the authors previously showed that all BTs, regardless of their intensity, have similar smoking abstinence effects at 12 months.(143) In addition, random-effects models that accounted for both bet…”
Self-citationWu, L., Sun, S., He, Y., & Zeng, J. (2015) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph120910235 · Cited by 46 · see citing works
“We used the longest follow-up time of smoking abstinence, as used previously [40,41].”
MethodA Meta-Analysis of Brief Tobacco Interventions for Use in Integrated Primary Care
Wray, J. M., Funderburk, J. S., Acker, J. D., Wray, L. O., & Maisto, S. A. (2017) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntx212 · Cited by 47 · see citing works
The cost-effectiveness of psychotherapy for the major psychiatric diagnoses.
Lazar, S. (2014) · Psychodynamic Psychiatry · doi:10.1521/pdps.2014.42.3.423 · Cited by 44 · see citing works
Chan, S. S. C., Leung, D. Y. P., Wong, D., Lau, C., Wong, V. T., & Lam, T. (2011) · Addiction · doi:10.1111/j.1360-0443.2011.03733.x · Cited by 43 · see citing works
Kumar, M. S., Sarma, P. S., & Thankappan, K. R. (2011) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2011.10.026 · Cited by 43 · see citing works
Cherrington, A., Williams, J. H., Foster, P. P., Coley, H. L., Kohler, C. L., Allison, J. J., Kiefe, C. I., Volkman, J. E., & Houston, T. K. (2015) · BMC Research Notes · doi:10.1186/s13104-015-1513-1 · Cited by 41 · see citing works
Meta‐analysis of safety for low event‐rate binomial trials
Shuster, J. J., Guo, J. D., & Skyler, J. S. (2012) · Research Synthesis Methods · doi:10.1002/jrsm.1039 · Cited by 39 · see citing works
“After all, it was the meta-analysis in Nissen and Wolski (2007) that triggered FDA hearings in 2007. The aim of this subsection is to present this high profile example which demonstrates the importance of properly presenting the nature of the parameter being estimated. Nissen and Wolski (2007) published a meta-analysi…”
MethodInfluentialCulturally Tailored Smoking Cessation for Adult American Indian Smokers
Smith, S. S., Arndt, L. M. R., Caskey, M., Fossum, J., Strickland, R., Culhane, J., & Waukau, J. (2014) · The Counseling Psychologist · doi:10.1177/0011000014542601 · Cited by 39 · see citing works
“…significant contributions of psychosocial factors in the initiation and maintenance of smoking combined with high rates of psychiatric comorbidities in smokers (Mackowick, Lynch, Weinberger, & George, 2012), counseling clearly plays an important role in cessation treatment (Mottillo et al., 2009).”
BackgroundLotufo, P. A. (2015) · Sao Paulo Medical Journal · doi:10.1590/1516-3180.2015.13320018 · Cited by 39 · see citing works
Ali, A. Y., Safwat, T., Onyemelukwe, G. C., Otaibi, M. A. A., Amir, A., Nawas, Y. N., Aouina, H., Afif, M. H., & Bolliger, C. T. (2012) · Respiration · doi:10.1159/000337726 · Cited by 37 · see citing works
Rini, C. K., Porter, L. S., Somers, T. J., McKee, D. C., & Keefe, F. J. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.3374 · Cited by 35 · see citing works
“Empirical support for the efficacy of behavioral interventions has been shown in research focused on disease prevention (eg, seeking to increase health promoting behaviors or to decrease health-damaging behaviors [3-6]) as well as research focused on helping people manage symptoms of diagnosed physical and mental heal…”
Jones, G. M., Lipson, J., & Nock, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-14809-3 · Cited by 27 · see citing works
Giovancarli, C., Malbos, É., Baumstarck, K., Parola, N., Pélissier, M.-F., Lançon, C., Auquier, P., & Boyer, L. (2016) · Trials · doi:10.1186/s13063-016-1224-5 · Cited by 33 · see citing works
“The sample size was calculated [56] to obtain 80 % power to detect a 30 % difference between the two groups in the proportion of individuals with tobacco abstinence at 6 months (reference point = 30 % [36]).”
BackgroundMethodClassic Psychedelics in Addiction Treatment: The Case for Psilocybin in Tobacco Smoking Cessation
Johnson, M. W. (2022) · Current topics in behavioral neurosciences · doi:10.1007/7854_2022_327 · Cited by 33 · see citing works
Baskerville, N. B., Wong, K., Shuh, A., Abramowicz, A., Dash, D., Esmail, A., & Kennedy, R. D. (2018) · BMC Public Health · doi:10.1186/s12889-018-5050-4 · Cited by 32 · see citing works
“The need to incorporate peer support and counselling services is not new to cessation interventions [38, 39].”
BackgroundCigarette Smoking and Cardiovascular Disease: Lessons from Framingham
Filion, K. B., & Luepker, R. V. (2013) · Global Heart · doi:10.1016/j.gheart.2012.12.005 · Cited by 32 · see citing works
“Effective nonpharmacological smoking cessation therapies are also now available and include behavioral therapies such as individual, group, or telephone counseling [45] and alternative approaches such as acupuncture and hypnotherapy [46].”
BackgroundSelf-citationAyahuasca and tobacco smoking cessation: results from an online survey in Brazil
Daldegan‐Bueno, D., Maia, L. O., Massarentti, C. M., & Tófoli, L. F. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06063-2 · Cited by 32 · see citing works
Proactive Referral to Behavioral Smoking Cessation Programs by Healthcare Staff: A Systematic Review
van Westen-Lagerweij, N. A., Walters, B. H., Potyka, F., Croes, E. A., & Willemsen, M. C. (2022) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntac262 · Cited by 31 · see citing works
Current developments in behavioral interventions for tobacco cessation
Murthy, P., & Nanjayya, S. B. (2010) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e328336653f · Cited by 28 · see citing works
Web-based Approach Bias Modification in smokers: A randomized-controlled study
Wittekind, C. E., Lüdecke, D., & Cludius, B. (2018) · Behaviour Research and Therapy · doi:10.1016/j.brat.2018.12.003 · Cited by 28 · see citing works
Gmel, G. E., Gaume, J., Bertholet, N., Flückiger, J., & Daeppen, J. (2012) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2012.07.005 · Cited by 27 · see citing works
Smoking cessation in groups--who benefits in the long term?
Wenig, J., Erfurt, L., Kröger, C. B., & Nowak, D. (2013) · Health Education Research · doi:10.1093/her/cyt086 · Cited by 26 · see citing works
“Despite, the classification and evaluation of quit rates of the ‘RauchfreiProgramm’ is still possible since abstinence rates of self-quit attempts and of other interventions have been thoroughly examined in numerous studies [8, 9, 42].”
BackgroundMethodTrends in Smoking Among Adults From 1980 to 2009: The Minnesota Heart Survey
Filion, K. B., Steffen, L. M., Duval, S., Jacobs, D. R., BLACKBURN, H. W., & Luepker, R. V. (2011) · American Journal of Public Health · doi:10.2105/ajph.2011.300162 · Cited by 25 · see citing works
Self-citationMalbos, É., Borwell, B., Einig-Iscain, M., Korchia, T., Cantalupi, R., Boyer, L., & Lançon, C. (2022) · Psychological Medicine · doi:10.1017/s0033291722002070 · Cited by 24 · see citing works
“The primary measure was the proportion of individuals with maintenance of their tobacco abstinence at the completion of the protocol (Lancaster, Stead, & Cahill, 2008; Mottillo et al., 2009).”
BackgroundBerg, C. J., Ahluwalia, J. S., & Cropsey, K. L. (2013) · Journal of Correctional Health Care · doi:10.1177/1078345813499307 · Cited by 23 · see citing works
Williams, J. M., Steinberg, M. L., Kenefake, A., & Burke, M. V. (2016) · Journal of Addiction Medicine · doi:10.1097/adm.0000000000000239 · Cited by 23 · see citing works
“, 2008), although the average total duration of group or individual tobacco counseling is rarely more than 15 hours (Mottillo et al., 2009).”
BackgroundBecoña, E., Martínez-Vispo, C., Senra, C., López‐Durán, A., Rodríguez‐Cano, R., & del Río, E. F. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1301-7 · Cited by 24 · see citing works
“Previous studies of cognitive behavioral interventions for smoking cessation [20, 33] and studies of cognitive behavioral interventions for smoking cessation with components targeting depressive symptoms [24, 31] suggest that quit rates after treatment may range between 28% and 61.”
BackgroundSmoking Cessation in Patients With Acute Coronary Syndrome
Franck, C., Filion, K. B., & Eisenberg, M. J. (2018) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2018.01.017 · Cited by 23 · see citing works
Self-citationJawad, A., Patel, D., Brima, N., & Stephenson, J. (2019) · Sexual & Reproductive Healthcare · doi:10.1016/j.srhc.2019.100461 · Cited by 23 · see citing works
“No qualifications 3(10) 3(13) 2(2) 7(3)”
BackgroundInfluentialSchuman‐Olivier, Z., Hoeppner, B. B., Evins, A. E., & Brewer, J. A. (2014) · Substance Use & Misuse · doi:10.3109/10826084.2014.850254 · Cited by 22 · see citing works
“…MA Address correspondence to: Zev Schuman-Olivier, Center for Addiction Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; E-mail: zschuman@cha.harvard.edu only about 5% to 20% of smokers remain abstinent 6 months after a cessation attempt (Mottillo et al., 2009).”
Backgroundde Viron, S., Malats, N., der Heyden, J. V., Oyen, H. J. V., & Brand, A. M. (2013) · Public Health Genomics · doi:10.1159/000351453 · Cited by 21 · see citing works
Text messaging in smoking cessation: the txt2stop trial
Bennett, D., & Emberson, J. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60882-9 · Cited by 20 · see citing works
Attempting Tobacco Cessation - An Oral Physician's Perspective
Pai, A., & Prasad, S. (2012) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2012.13.10.4973 · Cited by 19 · see citing works
Two brief valid measures of therapeutic alliance in counseling for tobacco dependence
Warlick, C. A., Richter, K. P., Catley, D., Gajewski, B. J., Martin, L. E., & Mussulman, L. M. (2017) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2017.12.010 · Cited by 19 · see citing works
“Counseling is an effective intervention for smoking cessation, increasing the likelihood of quitting by 40–60% compared to minimal support (Mottillo et al., 2008).”
Hogea, L., Tabugan, D. C., Costea, I., Albai, O., Nussbaum, L. A., Cojocaru, A., Corsaro, L., & Anghel, T. (2025) · Medicina · doi:10.3390/medicina61020278 · Cited by 19 · see citing works
“Additionally, in concordance with older studies, many participants noted that the acute effects of psilocybin, including heightened emotional awareness and introspection, overshadowed any withdrawal symptoms they might have experienced, making it easier to abstain from smoking [77,78].”
Predicting use of assistance when quitting: A longitudinal study of the role of quitting beliefs
Myers, M. G., Strong, D. R., Linke, S., Hofstetter, C. R., & Al‐Delaimy, W. K. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.02.003 · Cited by 18 · see citing works
“Unassisted quitting, where the smoker does not employ any evidence-based treatment, is thus the norm, despite better cessation outcomes when using smoking cessation assistance (Fiore et al., 2008; Mottillo et al., 2009; Piper et al., 2009).”
BackgroundZhang, Z., & Fang, H. (2016) · IEEE/ACM Conference on Connected Health: Applications, Systems and Engineering Technologies · doi:10.1109/chase.2016.19 · Cited by 18 · see citing works
Col, P. D., Baron, C., Guillaumin, C., Bouquet, É., & Fanello, S. (2010) · Revue des Maladies Respiratoires · doi:10.1016/j.rmr.2010.03.001 · Cited by 18 · see citing works
MIFuzzy clustering for incomplete longitudinal data in smart health
Fang, H. (2017) · Smart Health · doi:10.1016/j.smhl.2017.04.002 · Cited by 18 · see citing works
Jones, C. M., & Schüz, B. (2021) · Journal of Behavioral Medicine · doi:10.1007/s10865-021-00248-4 · Cited by 17 · see citing works
Cordero, A., Bertoméu, V., Mazón, P., Cosín, J., Galve, E., Lekuona, I., de la Guía-Galipienso, F., & González‐Juanatey, J. R. (2012) · Revista Española de Cardiología · doi:10.1016/j.recesp.2012.03.012 · Cited by 17 · see citing works
Vilardaga, R., Heffner, J. L., Mercer, L. D., & Bricker, J. B. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.07.008 · Cited by 17 · see citing works
“Unfortunately, although there has been considerable innovation in pharmacotherapeutic interventions for smoking cessation over the past 25 years, behavioral interventions have seen little change during this time (Mottillo et al., 2009).”
BackgroundKotsen, C., Santorelli, M. L., Bloom, E. L., Goldstein, A. O., Ripley‐Moffitt, C., Steinberg, M. B., Burke, M. V., & Foulds, J. (2018) · Nicotine & Tobacco Research · doi:10.1093/ntr/nty162 · Cited by 17 · see citing works
“Second, Mottillo et al. 16 conducted a meta-analysis of individual, group, and telephone counseling outcomes from 50 RCTs ( N = 26 927) conducted in Europe, North America, and Australia.”
BackgroundSalloum, R. G., Rojewski, A. M., Piper, M. E., Blalock, J. A., Borrelli, B., Boyce, L. M., Minnix, J. A., Dogar, O. F., Tomko, R. L., Jorenby, D. E., et al. (2021) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntab140 · Cited by 15 · see citing works
Wilson, S. M., Hair, L. P., Hertzberg, J. S., Kirby, A. C., Olsen, M. K., Lindquist, J. H., Maciejewski, M. L., Beckham, J. C., & Calhoun, P. S. (2016) · Contemporary Clinical Trials · doi:10.1016/j.cct.2016.08.008 · Cited by 14 · see citing works
LGBTQ Youth and Young Adult Perspectives on a Culturally Tailored Group Smoking Cessation Program
Baskerville, N. B., Shuh, A., Wong, K., Dash, D., & Abramowicz, A. (2017) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntx011 · Cited by 14 · see citing works
Figueiró, L. R., Barros, H. M. T., Ferigolo, M., & Dantas, D. C. M. (2017) · Trends in Psychiatry and Psychotherapy · doi:10.1590/2237-6089-2016-0041 · Cited by 13 · see citing works
Multiple Perspectives on Tobacco Use among Youth with Mental Health Disorders and Addictions
Morris, C. D., May, M. G., Devine, K., Smith, S. M., DeHay, T. L., & Mahalik, J. L. (2011) · American Journal of Health Promotion · doi:10.4278/ajhp.100610-qual-179 · Cited by 13 · see citing works
Psycho- und Pharmakotherapie bei schädlichem Tabakgebrauch und -abhängigkeit
Batra, A., Petersen, K. U., Hoch, E., Mann, K. F., Kröger, C. B., Schweizer, C., Jähne, A., Rüther, T., Thürauf, N., & Mühlig, S. (2015) · Der Nervenarzt · doi:10.1007/s00115-015-0037-1 · Cited by 12 · see citing works
HIV-related pneumococcal disease prevention in adults
Feldman, C. H., Anderson, R., & Rossouw, T. M. (2017) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2017.1289841 · Cited by 12 · see citing works
“Pharmacotherapy, such as nicotine replacement therapy, bupropion, and varenicline, do not seem to have significant interactions with cART [164] and may have additional benefits when combined with behavioral interventions although not all meta-analyses support this view [155,161,165].”
BackgroundMeng, Y., Xiang, S., Qu, L., & Li, Y. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1361186 · Cited by 12 · see citing works
“However, inconsistent effectiveness reported by RCTs and meta-analysis of the above pharmacological therapies is not excellent enough, and the relapse rate remains high (3).”
BackgroundAlba, L. H., Murillo, R., & Castillo, J. S. (2013) · Salud Pública de México · doi:10.1590/s0036-36342013000200012 · Cited by 10 · see citing works
Girgis, S. T., Adily, A., Velasco, M.-J., Zwar, N. A., Jalaludin, B. B., & Ward, J. (2011) · Australian Journal of Primary Health · doi:10.1071/py10066 · Cited by 10 · see citing works
“Further, there is accumulating evidence to suggest that telephone counselling, whether or not initiated by calls to help lines, result in substantial increases in smoking abstinence (Stead et al. 2006; Mottillo et al. 2009).”
BackgroundBartels, C., AbuHaliga, A. R. Y., McGee, H. M., Morgan, K., McElvaney, N. G., & Doyle, F. (2012) · Irish Journal of Medical Science (1971 -) · doi:10.1007/s11845-011-0792-3 · Cited by 10 · see citing works
Wu, L., He, Y., Jiang, B., Zhang, D., Tian, H., Zuo, F., Lam, T. H., & Cheung, Y. T. D. (2015) · BMC Public Health · doi:10.1186/s12889-015-1749-7 · Cited by 9 · see citing works
“In general, commonly used behavioral intervention categories fall into two categories: brief or minimal interventions and intensive interventions [9].”
BackgroundAcar, T., Gallagher, C., Gören, Y., Erbas, B., & Özkara, A. (2024) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph21030310 · Cited by 9 · see citing works
“Accordingly, the importance of cognitive behavioral therapy in quitting smoking was found to be high in our study, similar to previous studies [41,42].”
BackgroundResultSmoking Cessation Strategies After Acute Coronary Syndrome
Nazir, A., Ujjar, S. S., Seddiki, M., Jheinga, M., & Fan, L. M. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14041388 · Cited by 9 · see citing works
“A meta-analysis of four RCTs showed that intensive behavioural therapy resulted in better smoking cessation [21].”
Harm reduction in tobacco control: where do we draw the line?
Al‐Hamdani, M., & Manly, E. (2022) · Journal of Public Health Policy · doi:10.1057/s41271-021-00327-5 · Cited by 9 · see citing works
Salisbury, C., O’Cathain, A., Thomas, C., Edwards, L., Montgomery, A. A., Hollinghurst, S. P., Large, S., Nicholl, J. P., Pope, C. J., Rogers, A. E., et al. (2017) · Programme Grants for Applied Research · doi:10.3310/pgfar05010 · Cited by 9 · see citing works
Hooper, M. W., & Carver, C. S. (2016) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000109 · Cited by 9 · see citing works
“Among the best approaches for smoking cessation is CBT with adjuvant pharmacotherapy (Fiore et al., 2008; Lemmens, Oenema, Knut, & Brug, 2008; Moore et al., 2009; Mottillo et al., 2009; Webb, 2008).”
BackgroundKim, B. S., Lim, Y., Shin, J., Kim, S. H., Roh, S., Choi, Y. W., Shin, J., Park, J., & Kim, K.-S. (2019) · Global Heart · doi:10.1016/j.gheart.2019.04.001 · Cited by 9 · see citing works
“There are several well-known smoking cessation treatments, including behavioral and pharmacological treatment [7,8].”
BackgroundTseng, T., Celestin, M. D., Yu, Q., Li, M., Luo, T., & Moody‐Thomas, S. (2021) · Frontiers in Public Health · doi:10.3389/fpubh.2021.712635 · Cited by 8 · see citing works
“A 2009 meta-analysis found that intensive interventions such as behavioral group counseling were more likely to promote smoking cessation compared to controls (10).”
Background
- Authors
- Mottillo, S., Filion, K. B., Bélisle, P., Joseph, L., Gervais, A., O'Loughlin, J., Paradis, G., Pihl, R., Pilote, L., Rinfret, S., Tremblay, M., & Eisenberg, M. J.
- Affiliations
- Jewish General Hospital (CA)
- McGill University Health Centre (CA)
- McGill University (CA)
- Corresponding author
- Eisenberg, Mark J.
- ORCID
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-12-24
- Volume
- 30
- Issue
- 6
- Pages
- 718-730
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2025716661
- Cited by
- 171
- References
- 78
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 4 · 2023: 6 · 2022: 14 · 2021: 5 · 2020: 4 · 2019: 3 · 2018: 10 · 2017: 11 · 2016: 9 · 2015: 18 · 2014: 13 · 2013: 19 · 2012: 14
- FWCI
- 1.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Heart Journal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
- Keywords
- smoking cessation, behavioral interventions, brief advice, individual counseling, group counseling, telephone counseling, smoking abstinence, treatment efficacy
- MeSH terms
- Smoking Prevention, Behavior Therapy, Female, Humans, Male, United States, Randomized Controlled Trials as Topic, Smoking Cessation
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