Validation of the AF-QoL, a disease-specific quality of life questionnaire for patients with atrial fibrillation
Abstract
AIMS: To assess the performance of AF-QoL, a quality of life questionnaire for patients with atrial fibrillation (AF). METHODS AND RESULTS: Observational, prospective, multicentre study in 29 Spanish centres. Three patients' groups were identified at baseline visit: AF patients receiving a new therapeutic intervention according to physician criteria (intervention group); AF clinically stable patients according to physician evaluation (clinically stable group); and patients in a stable condition for more than 1 year after a myocardial infarction (control group). All patients were > or = 18 years. Follow-up visit was at 1 month (clinically stable group) and 3 +/- 1 months (intervention group). Sociodemographic and clinical information was gathered. AF-QoL, SF-36, and patient self-perception of general health status were administered. A total of 417 patients was included. Mean (SD) age was 61.2 (12.4), 31.4% women. AF-QoL mean overall score in AF patients (43.6) was lower (worse health-related quality of life, HRQoL) than in the control group (51.7) (P < 0.05). At baseline, patients with higher frequency of symptoms (P < 0.05) and worse NYHA functional class (P < 0.01) reported lower AF-QoL scores. AF-QoL and SF-36 correlated in all of their domains (r = 0.14-0.8, P < 0.01). AF-QoL showed good internal consistency (0.92) and test-retest reliability (0.86). CONCLUSION: AF-QoL is a valid and reliable HRQoL measure. Further investigation is recommended before using it in clinical practice.
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Assessment of quality of life is constrained by a lack of cross-validation of the several AF-specific quality-of-life tools.
“Assessment of quality of life is further constrained by a lack of cross-validation of the several AF-specific quality-of-life tools.”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [187]
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Self-citation
- Authors
- Arribas, F., Ormaetxe, J. M., Peinado, R., Perulero, N., Ramirez, P., & Badia, X.
- Affiliations
- Hospital Universitario 12 De Octubre (ES)
- Hospital de Basurto (ES)
- Hospital Universitario La Paz (ES)
- Corresponding author
- Badia, X.
- Venue
- Europace
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-01-06
- Volume
- 12
- Issue
- 3
- Pages
- 364-370
- ISSN
- 1099-5129 (ISSN-L)
- 1532-2092
- OpenAlex
- W2164691945
- Cited by
- 91
- References
- 25
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 5 · 2023: 4 · 2022: 1 · 2021: 8 · 2020: 1 · 2019: 9 · 2018: 2 · 2017: 8 · 2016: 10 · 2015: 9 · 2014: 11 · 2013: 5 · 2012: 3
- FWCI
- 3.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- EP Europace (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Social Sciences › Education › Health Education and Validation
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- atrial fibrillation, health-related quality of life, disease-specific questionnaire, questionnaire validation, SF-36, NYHA functional class, symptom frequency, internal consistency, test-retest reliability, myocardial infarction
- MeSH terms
- Aged, Atrial Fibrillation, Female, Follow-Up Studies, Health Status, Humans, Male, Middle Aged, Quality of Life, Surveys and Questionnaires, Spain, Reproducibility of Results
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