Cited by 154Atrial Fibrillation Management and OutcomesHealth Systems, Economic Evaluations, Quality of LifeHealth Promotion and Cardiovascular Prevention

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Cost-effectiveness of mass screening for untreated atrial fibrillation using intermittent ECG recording

Aronsson, Mattias, Svennberg, Emma, Rosenqvist, Mårten, Engdahl, Johan, Al-Khalili, Faris, Friberg, Leif, Frykman-Kull, Viveka, Levin, Lars-Åke·2015·Europace

DOI 10.1093/europace/euv083

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Abstract

AIMS: The aim of this study was to estimate the cost-effectiveness of 2 weeks of intermittent screening for asymptomatic atrial fibrillation (AF) in 75/76-year-old individuals. METHODS AND RESULTS: The cost-effectiveness analysis of screening in 75-year-old individuals was based on a lifelong decision analytic Markov model. In this model, 1000 hypothetical individuals, who matched the population of the STROKESTOP study, were simulated. The population was analysed for different parameters such as prevalence, AF status, treatment with oral anticoagulation, stroke risk, utility, and costs. In the base-case scenario, screening of 1000 individuals resulted in 263 fewer patient-years with undetected AF. This implies eight fewer strokes, 11 more life-years, and 12 more quality-adjusted life years (QALYs) per 1000 screened individuals. The screening implies an incremental cost of €50 012, resulting in a cost of €4313 per gained QALY and €6583 per avoided stroke. CONCLUSIONS: With the use of a decision analytic simulation model, it has been shown that screening for asymptomatic AF in 75/76-year-old individuals is cost-effective.

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Authors: Aronsson, M., Svennberg, E., Rosenqvist, M., Engdahl, J., Al-Khalili, F., Friberg, L., Frykman-Kull, V., & Levin, L.-Å.
Affiliations: Linköping University (SE)
Danderyds sjukhus (SE)
Hallands sjukhus Halmstad (SE)
Corresponding author: Aronsson, Mattias
ORCID: Aronsson, Mattias
Svennberg, Emma
Rosenqvist, Mårten
Engdahl, Johan
Friberg, Leif
Levin, Lars-Åke
Venue: Europace
Publisher: Oxford University Press (OUP)
Published: 2015-04-12
Volume: 17
Issue: 7
Pages: 1023-1029
ISSN: 1099-5129 (ISSN-L)
1532-2092
DOI: 10.1093/europace/euv083
OpenAlex: W2160206914
Cited by: 154
References: 48
Citations by year: 2026: 2 · 2025: 8 · 2024: 7 · 2023: 9 · 2022: 13 · 2021: 21 · 2020: 15 · 2019: 28 · 2018: 14 · 2017: 16 · 2016: 19 · 2015: 2
FWCI: 12.36
Type: journal article
Language: en
Open access: closed
Locations: EP Europace (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
Keywords: atrial fibrillation, mass screening, asymptomatic atrial fibrillation, cost-effectiveness, older adults, stroke prevention, oral anticoagulation, quality-adjusted life years
MeSH terms: Aged, Atrial Fibrillation, Cost-Benefit Analysis, Electrocardiography, Female, Humans, Male, Mass Screening, Quality of Life, Sweden, Prevalence, Survival Rate, Health Care Costs, Risk Assessment

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Cost-effectiveness of mass screening for untreated atrial fibrillation using intermittent ECG recording

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