Carbon recycling by cyanobacteria: Improving CO2 fixation through chemical production

The Oceanic Sink for Anthropogenic CO ₂

Sabine, C. L., Feely, R. A., Gruber, N., Key, R. M., Lee, K., Bullister, J. L., Wanninkhof, R., Wong, C. S., Wallace, D. W. R., Tilbrook, B., et al. (2004) · Science · doi:10.1126/science.1097403 · Cited by 4,035 · see citing works

Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements

Lutz, R. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.6.1203 · Cited by 1,696 · see citing works

Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde

Atsumi, S., Higashide, W., & Liao, J. C. (2009) · Nature Biotechnology · doi:10.1038/nbt.1586 · Cited by 870 · see citing works

The Importance of Energy Balance in Improving Photosynthetic Productivity

Kramer, D. M., & Evans, J. R. (2011) · Plant Physiology · doi:10.1104/pp.110.166652 · Cited by 494 · see citing works

Advancing Our Understanding and Capacity to Engineer Nature’s CO2-Sequestering Enzyme, Rubisco

Whitney, S. M., Houtz, R. L., & Alonso, H. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.164814 · Cited by 468 · see citing works

Metabolic engineering of cyanobacteria for 1-butanol production from carbon dioxide

Lan, E. I., & Liao, J. C. (2011) · Metabolic Engineering · doi:10.1016/j.ymben.2011.04.004 · Cited by 382 · see citing works

Cyanobacterial conversion of carbon dioxide to 2,3-butanediol

Oliver, J. W. K., Machado, I. M. P., Yoneda, H., & Atsumi, S. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1213024110 · Cited by 382 · see citing works

Photosynthetic production of ethanol from carbon dioxide in genetically engineered cyanobacteria

Gao, Z., Zhao, H. F., Li, Z., Tan, X., & Lü, X. (2012) · Energy & Environmental Science · doi:10.1039/c2ee22675h · Cited by 377 · see citing works

Synechococcus elongatus UTEX 2973, a fast growing cyanobacterial chassis for biosynthesis using light and CO2

Yu, J., Liberton, M., Cliften, P. F., Head, R. D., Jacobs, J., Smith, R. D., Koppenaal, D., Brand, J. J., & Pakrasi, H. B. (2015) · Scientific Reports · doi:10.1038/srep08132 · Cited by 372 · see citing works

Rerouting Carbon Flux to Enhance Photosynthetic Productivity

Ducat, D. C., Avelar-Rivas, J. A., Way, J. C., & Silver, P. A. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.07901-11 · Cited by 362 · see citing works

Optimizing R ubisco and its regulation for greater resource use efficiency

CARMO‐SILVA, E., Scales, J. C., Madgwick, P. J., & Parry, M. A. J. (2014) · Plant Cell & Environment · doi:10.1111/pce.12425 · Cited by 345 · see citing works

Catalysis and regulation in Rubisco

Andersson, I. (2007) · Journal of Experimental Botany · doi:10.1093/jxb/ern091 · Cited by 316 · see citing works

Spatially Ordered Dynamics of the Bacterial Carbon Fixation Machinery

Savage, D. F., Afonso, B., Chen, A. H., & Silver, P. A. (2010) · Science · doi:10.1126/science.1186090 · Cited by 308 · see citing works

Biogenesis of a Bacterial Organelle: The Carboxysome Assembly Pathway

Cameron, J. C., Wilson, S. C., Bernstein, S. L., & Kerfeld, C. A. (2013) · Cell · doi:10.1016/j.cell.2013.10.044 · Cited by 305 · see citing works

Synthetic biology of cyanobacteria: unique challenges and opportunities

Berla, B. M., Saha, R., Immethun, C. M., Maranas, C. D., Moon, T. S., & Pakrasi, H. B. (2013) · Frontiers in Microbiology · doi:10.3389/fmicb.2013.00246 · Cited by 305 · see citing works

Metabolic engineering for advanced biofuels production from Escherichia coli

Atsumi, S., & Liao, J. C. (2008) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2008.08.008 · Cited by 297 · see citing works

Expression of Human Carbonic Anhydrase in the Cyanobacterium Synechococcus PCC7942 Creates a High CO2-Requiring Phenotype

Price, G. D., & Badger, M. R. (1989) · PLANT PHYSIOLOGY · doi:10.1104/pp.91.2.505 · Cited by 271 · see citing works

Flux Balance Analysis of Cyanobacterial Metabolism: The Metabolic Network of Synechocystis sp. PCC 6803

Knoop, H., Gründel, M., Zilliges, Y., Lehmann, R., Hoffmann, S., Lockau, W., & Steuer, R. (2013) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003081 · Cited by 248 · see citing works

Cyanobacteria as a Platform for Biofuel Production.

Nozzi, N. E., Oliver, J. W. K., & Atsumi, S. (2013) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2013.00007 · Cited by 227 · see citing works

Global metabolic rewiring for improved CO2 fixation and chemical production in cyanobacteria

Kanno, M., Carroll, A. L., & Atsumi, S. (2017) · Nature Communications · doi:10.1038/ncomms14724 · Cited by 220 · see citing works

pH determines the energetic efficiency of the cyanobacterial CO 2 concentrating mechanism

Mangan, N. M., Flamholz, A. I., Hood, R. D., Milo, R., & Savage, D. F. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1525145113 · Cited by 214 · see citing works

Cyanobacterial metabolic engineering for biofuel and chemical production

Oliver, N. J., Rabinovitch-Deere, C. A., Carroll, A. L., Nozzi, N. E., Case, A. E., & Atsumi, S. (2016) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2016.08.023 · Cited by 165 · see citing works

Exploring metabolic engineering design principles for the photosynthetic production of lactic acid by Synechocystis sp. PCC6803

Angermayr, S. A., van der Woude, A. D., Correddu, D., Vreugdenhil, A., Verrone, V., & Hellingwerf, K. J. (2014) · Biotechnology for Biofuels · doi:10.1186/1754-6834-7-99 · Cited by 163 · see citing works

Engineering a synthetic pathway in cyanobacteria for isopropanol production directly from carbon dioxide and light

Kusakabe, T., Tatsuke, T., Tsuruno, K., Hirokawa, Y., Atsumi, S., Liao, J. C., & Hanai, T. (2013) · Metabolic Engineering · doi:10.1016/j.ymben.2013.09.007 · Cited by 149 · see citing works

Oxygen-tolerant coenzyme A-acylating aldehyde dehydrogenase facilitates efficient photosynthetic n-butanol biosynthesis in cyanobacteria

Lan, E. I., Ro, S. Y., & Liao, J. C. (2013) · Energy & Environmental Science · doi:10.1039/c3ee41405a · Cited by 146 · see citing works

Biosynthesis of platform chemical 3-hydroxypropionic acid (3-HP) directly from CO2 in cyanobacterium Synechocystis sp. PCC 6803

Wang, Y., Sun, T., Gao, X., Shi, M., Wu, L., Chen, L., & Zhang, W. (2015) · Metabolic Engineering · doi:10.1016/j.ymben.2015.10.008 · Cited by 139 · see citing works

Metabolic design for cyanobacterial chemical synthesis

Oliver, J. W. K., & Atsumi, S. (2014) · Photosynthesis Research · doi:10.1007/s11120-014-9997-4 · Cited by 134 · see citing works

Unique attributes of cyanobacterial metabolism revealed by improved genome-scale metabolic modeling and essential gene analysis

Broddrick, J. T., Rubin, B. E., Welkie, D. G., Du, N., Mih, N., Diamond, S., Lee, J. J., Golden, S. S., & Palsson, B. Ø. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1613446113 · Cited by 127 · see citing works

Engineering cyanobacteria as photosynthetic feedstock factories

Hays, S. G., & Ducat, D. C. (2014) · Photosynthesis Research · doi:10.1007/s11120-014-9980-0 · Cited by 122 · see citing works

Combinatorial optimization of cyanobacterial 2,3-butanediol production

Oliver, J. W. K., Machado, I. M. P., Yoneda, H., & Atsumi, S. (2014) · Metabolic Engineering · doi:10.1016/j.ymben.2014.01.001 · Cited by 116 · see citing works

Photosynthetic production of 2-methyl-1-butanol from CO2 in cyanobacterium Synechococcus elongatus PCC7942 and characterization of the native acetohydroxyacid synthase

Shen, C. R., & Liao, J. C. (2012) · Energy & Environmental Science · doi:10.1039/c2ee23148d · Cited by 116 · see citing works

Introduction of a Synthetic CO2-fixing Photorespiratory Bypass into a Cyanobacterium

Shih, P. M., Zarzycki, J., Niyogi, K., & Kerfeld, C. A. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.c113.543132 · Cited by 100 · see citing works

Synechocystis PCC 6803 overexpressing RuBisCO grow faster with increased photosynthesis

Liang, F., & Lindblad, P. C. (2017) · Metabolic Engineering Communications · doi:10.1016/j.meteno.2017.02.002 · Cited by 93 · see citing works

Overview of fusion tags for recombinant proteins

Kosobokova, E. N., Skrypnik, K. A., & Kosorukov, V. S. (2016) · Biochemistry (Moscow) · doi:10.1134/s0006297916030019 · Cited by 88 · see citing works

Cloning, characterization and expression of carbonic anhydrase from the cyanobacterium Synechocystis PCC6803

So, A. K.-C., & Espie, G. S. (1998) · Plant Molecular Biology · doi:10.1023/a:1005959200390 · Cited by 85 · see citing works

Development of an activity-directed selection system enabled significant improvement of the carboxylation efficiency of Rubisco

Cai, Z., Liu, G., Zhang, J., & Li, Y. (2014) · Protein & Cell · doi:10.1007/s13238-014-0072-x · Cited by 81 · see citing works

Enhancing CO2 bio-mitigation by genetic engineering of cyanobacteria

Chen, P.-H., Liu, H.-L., Chen, Y., Cheng, Y.-H., Lin, W.-L., Yeh, C.-H., & Chang, C.-H. (2012) · Energy & Environmental Science · doi:10.1039/c2ee21124f · Cited by 81 · see citing works

Introducing extra NADPH consumption ability significantly increases the photosynthetic efficiency and biomass production of cyanobacteria

Zhou, J., Zhang, F., Meng, H., Zhang, Y., & Li, Y. (2016) · Metabolic Engineering · doi:10.1016/j.ymben.2016.08.002 · Cited by 80 · see citing works

Cyanobacterial production of 1,3-propanediol directly from carbon dioxide using a synthetic metabolic pathway

Hirokawa, Y., Maki, Y., Tatsuke, T., & Hanai, T. (2016) · Metabolic Engineering · doi:10.1016/j.ymben.2015.12.008 · Cited by 76 · see citing works

A carbon sink pathway increases carbon productivity in cyanobacteria

Oliver, J. W. K., & Atsumi, S. (2015) · Metabolic Engineering · doi:10.1016/j.ymben.2015.03.006 · Cited by 75 · see citing works

Over-expression of the β-carboxysomal CcmM protein in Synechococcus PCC7942 reveals a tight co-regulation of carboxysomal carbonic anhydrase (CcaA) and M58 content

Long, B. M., Rae, B. D., Badger, M. R., et al. (2011) · Photosynthesis Research · doi:10.1007/s11120-011-9659-8 · Cited by 66 · see citing works

Cyanobacterial chemical production

Case, A. E., & Atsumi, S. (2016) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2016.05.023 · Cited by 58 · see citing works

Identifying the Metabolic Differences of a Fast-Growth Phenotype in Synechococcus UTEX 2973

Mueller, T. J., Ungerer, J. L., Pakrasi, H. B., & Maranas, C. D. (2017) · Scientific Reports · doi:10.1038/srep41569 · Cited by 58 · see citing works

Inorganic Carbon Fluxes and Photosynthesis in Cyanobacteria — A Quantitative Model

Reinhold, L., Zviman, M., & Kaplan, A. (1987) · Springer eBooks · doi:10.1007/978-94-017-0519-6_62 · Cited by 57 · see citing works

Genome Engineering of the 2,3-Butanediol Biosynthetic Pathway for Tight Regulation in Cyanobacteria

Nozzi, N. E., & Atsumi, S. (2015) · ACS Synthetic Biology · doi:10.1021/acssynbio.5b00057 · Cited by 47 · see citing works

2,3 Butanediol production in an obligate photoautotrophic cyanobacterium in dark conditions via diverse sugar consumption

McEwen, J. T., Kanno, M., & Atsumi, S. (2016) · Metabolic Engineering · doi:10.1016/j.ymben.2016.03.004 · Cited by 43 · see citing works

New applications of synthetic biology tools for cyanobacterial metabolic engineering

Santos-Merino, M., Singh, A. K., & Ducat, D. C. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00033 · Cited by 222 · see citing works

A toolbox to engineer the highly productive cyanobacterium <i>Synechococcus</i> sp. PCC 11901

Victoria, A. J., Selão, T. T., Moreno-Cabezuelo, J. Á., Mills, L. A., Gale, G. A. R., Lea-Smith, D. J., & McCormick, A. J. (2024) · Plant Physiology · doi:10.1093/plphys/kiae261 · Cited by 28 · see citing works

Potential of Producing Flavonoids Using Cyanobacteria as a Sustainable Chassis

Jin, H., Wang, Y., Zhao, P., Wang, L., Zhang, S., Meng, D., Yang, Q., Cheong, L.-Z., Bi, Y., & Fu, Y. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c04632 · Cited by 17 · see citing works

Cyanobacteria as a Photosynthetic Chassis for Metabolic Pathway Engineering with Heterologous Gene Expression

Walshe, J., & Saha, S. K. (2026) · Current Issues in Molecular Biology · doi:10.3390/cimb48060638 · Cited by 1 · see citing works

Carboxysome Mispositioning Alters Growth, Morphology, and Rubisco Level of the Cyanobacterium Synechococcus elongatus PCC 7942

Rillema, R., Hoang, Y., MacCready, J. S., et al. (2021) · mBio · doi:10.1128/mbio.02696-20 · Cited by 25 · see citing works

Carbon Sequestration

Naorem, A. (2022) · Resonance · doi:10.1007/s12045-022-1416-0 · Cited by 2 · see citing works

Prospects of carbon capture and carbon sequestration using microalgae and macrophytes

Khalid, Z., Alam, S. N., Singh, B., & Guldhe, A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824270-4.00013-4 · Cited by 4 · see citing works

Carbon Sequestration by the Above Ground Biomass Pool in the South West Mau Forest of Kenya, 1985 - 2015

Kigomo, M. K., Mburu, D. M., Kinyanjui, J. M., et al. (2020) · Journal of environment and earth science · doi:10.7176/jees/10-8-05 · Cited by 4 · see citing works

Quantifying the effectiveness of climate change mitigation through forest plantations and carbon sequestration with an integrated land-use model

van Minnen, J. G., Strengers, B. J., Eickhout, B., Swart, R. J., & Leemans, R. (2008) · Carbon Balance and Management · doi:10.1186/1750-0680-3-3 · Cited by 69 · see citing works