Walking Performance and Cardiovascular Response: Associations With Age and Morbidity--The Health, Aging and Body Composition Study
Abstract
BACKGROUND: The long-distance corridor walk is a timed 400-meter walk test used to assess walking endurance in well-functioning men and women aged 70-79 in the Health, Aging and Body Composition Study. METHODS: We examined walking time along with heart rate and blood pressure response in relationship to prevalent chronic conditions, weight, physical activity, and markers of subclinical disease. Of 3075 participants, 2324 (76%) completed the test with heart rate and blood pressure responses in the range expected for a moderate level of exertion. RESULTS: Slower walking time was influenced by both clinical and subclinical disease, and also was strongly related to both low and high body weight and low self-reported physical activity. Heart rate and blood pressure responses were higher with several clinical and subclinical diseases, but heart rate response and recovery were more strongly related to walking time than to disease. Higher body mass index and lower physical activity were associated with greater heart rate response and recovery. CONCLUSIONS: The independent contribution of both clinical and subclinical disease to walking time supports the use of walking tests as a summary measure of disease in older adults. The independent association of walking time with physical activity suggests that it is sensitive to levels of fitness as well. Together these findings show that walking performance is a valid indicator of physiologic reserve in older adults.
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The link between fitness and functional capacity is well established.
“The link between fitness and functional capacity is well established (24,28), but rarely has objectively measured fitness been applied to identification of covert or impending mobility limitations (29).”
From Mobility Limitation in Self-Described Well-Functioning Older Adults: Importance of Endurance Walk Testing (2008) · cites this paper as [24]
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Inzitari, M., Pozzi, C., Ferrucci, L., Chiarantini, D., Rinaldi, L. A., Baccini, M., Pini, R., Masotti, G., Marchionni, N., & Bari, M. D. (2008) · Archives of Internal Medicine · doi:10.1001/archinte.168.12.1270 · Cited by 51 · see citing works
The Effect of Medication Use on Urinary Incontinence in Community‐Dwelling Elderly Women
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Editorial. Mobility Performance: A High-Tech Test for Geriatricians
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Self-citationAnalgesic Use for Knee and Hip Osteoarthritis in Community-Dwelling Elders
Marcum, Z. A., Perera, S., Donohue, J. M., Boudreau, R. M., Newman, A. B., Ruby, C. M., Studenski, S. A., Kwoh, C. K., Simonsick, E. M., Bauer, D. C., et al. (2011) · Pain Medicine · doi:10.1111/j.1526-4637.2011.01249.x · Cited by 39 · see citing works
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The clinical trial of Women On the Move through Activity and Nutrition (WOMAN) study
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A comparison of the relationship of 14 performance-based measures with frailty in older women
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de Liefde, I. I., Hoeks, S. E., van Gestel, Y. R. B. M., Klein, J., Bax, J. J., Verhagen, H. J. M., van Domburg, R. T., & Poldermans, D. (2009) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2009.02.022 · Cited by 30 · see citing works
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Brach, J. S., Wert, D. M., VanSwearingen, J. M., Newman, A. B., & Studenski, S. A. (2012) · Journal of Geriatric Physical Therapy · doi:10.1519/jpt.0b013e318243e5f9 · Cited by 26 · see citing works
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A genome-wide association study meta-analysis of clinical fracture in 10,012 African American women
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Exercise Capacity, Heart Failure Risk, and Mortality in Older Adults: The Health ABC Study
Georgiopoulou, V. V., Kalogeropoulos, A. P., Chowdhury, R., Binongo, J., Bibbins-Domingo, K. B., Rodondi, N., Simonsick, E. M., Harris, T. B., Newman, A. B., Kritchevsky, S. B., et al. (2016) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2016.08.041 · Cited by 22 · see citing works
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The Relationship Between Functional Status and Inflammatory Disease in Older Adults
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Cardiorespiratory Fitness and Muscular Strength on Arterial Stiffness in Older Adults
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Brain control of dual-task walking can be improved in aging and neurological disease
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- Authors
- Newman, A. B., Haggerty, C. L., Kritchevsky, S. B., Nevitt, M. C., & Simonsick, E. M.
- Affiliations
- University of Pittsburgh (US)
- University of Tennessee Health Science Center (US)
- University of California, San Francisco (US)
- National Institutes of Health (US)
- Venue
- The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-08-01
- Volume
- 58
- Issue
- 8
- Pages
- M715-M720
- ISSN
- 1079-5006 (ISSN-L)
- 1758-535X
- OpenAlex
- W2170484537
- Cited by
- 163
- References
- 30
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 8 · 2023: 3 · 2022: 2 · 2021: 4 · 2020: 2 · 2019: 4 · 2018: 3 · 2017: 10 · 2016: 10 · 2015: 10 · 2014: 8 · 2013: 11 · 2012: 8
- FWCI
- 16.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journals of Gerontology Series A (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (ANO1-AG-6-2101, ANO1-AG-6-2103, ANO1-AG-6-2106)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Keywords
- walking endurance, heart rate response, blood pressure response, heart rate recovery, cardiovascular response to exercise, older adults, chronic disease, subclinical disease, body mass index, physical activity, physical fitness, physiological reserve
- MeSH terms
- Aged, Aging, Blood Pressure, Body Weight, Cardiovascular Physiological Phenomena, Female, Health Status, Heart Rate, Humans, Male, Motor Activity, Body Mass Index, Walking
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