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Fibroblasts from different body parts exhibit distinct phenotypes in adult progeria Werner syndrome

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Phosphorylation-dependent WRN-RPA interaction promotes recovery of stalled forks at secondary DNA structure

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Distinct prognosis of mRNA expression of the five RecQ DNA-helicase family members – RECQL, BLM, WRN, RECQL4, and RECQL5 – in patients with breast cancer

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G-quadruplexes formation in the 5’UTRs of mRNAs associated with colorectal cancer pathways

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hSSB1 (NABP2/OBFC2B) modulates the DNA damage and androgen‐induced transcriptional response in prostate cancer

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A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4

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Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein

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DNA/RNA helicase DHX36 is required for late stages of spermatogenesis

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Mms1 is an assistant for regulating G-quadruplex DNA structures

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Cancer predisposition syndromes associated with myeloid malignancy

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How DNA secondary structures drive replication fork instability

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Guardians of the Genome: How the Single-Stranded DNA-Binding Proteins RPA and CST Facilitate Telomere Replication

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G-quadruplexes in Prague: A Bohemian Rhapsody.

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The Impact of Vitamin C on Different System Models of Werner Syndrome

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Human RecQ helicases in transcription-associated stress management: bridging the gap between DNA and RNA metabolism

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Cerebral Haemorrhage in a Young Patient With Atypical Werner Syndrome Due to Mutations in LMNA

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ssG4-seq for global profiling of strand-specific G-quadruplex structures in mammalian genomes

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Chromatin Immunoprecipitation Reveals p53 Binding to G-Quadruplex DNA Sequences in Myeloid Leukemia Cell Lines

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Discovery of a new hereditary RECQ helicase disorder RECON syndrome positions the replication stress response and genome homeostasis as centrally important processes in aging and age-related disease

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Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells

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Werner Syndrome as a Model of Human Aging

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An overview of RecQ helicases and related diseases

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Werner syndrome RECQ helicase participates in and directs maintenance of the protein complexes of constitutive heterochromatin in proliferating human cells

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Amelioration of premature aging in Werner syndrome stem cells by targeting SHIP/AKT pathway

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Folate modulates guanine-quadruplex frequency and DNA damage in Werner syndrome.

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G-Quadruplex Resolving by Specific Helicases

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Impact of Reactive Oxygen Species and G-Quadruplexes in Telomeres and Mitochondria

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From cooperation to conflicts – A complicated relationship between transcription and replication

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BMI1 represses G-quadruplex DNA formation to maintain genomic stability during replication

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Development of an exon 27-skipping antisense oligonucleotide as a targeted therapy for refractory skin ulcers in Werner syndrome

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Transcriptional regulation by a RecQ helicase

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G-Quadruplex Resolving by Specific Helicases

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DNA Helicase Deficiency Disorders

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Phosphorylation-Dependent Association of WRN with RPA is Required for Recovery of Replication Forks Stalled at Secondary DNA StructuresPreprint

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A universal molecular mechanism driving agingPreprint

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Helicases and Their Relevance to Aging

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A WRN Nonsense Mutation, p.R1406X, is Not a Risk Factor of Breast Cancer

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Faculty Opinions recommendation of Fundamentals of G-quadruplex biology.

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G-quadruplexes as key motifs in transcriptomics

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Alternative DNA structures in hematopoiesis and adaptive immunity

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Additional file 2 of Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells

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James German and the Quest to Understand Human RECQ Helicase Deficiencies

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BMI1-mediated heterochromatinization represses G-quadruplex DNA formation to maintain genomic stability during replicationPreprint

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WRN helicase upregulates mitophagy by resolving an intricate nexus of G-quadruplexes-R loops-ATG7 pre-mRNA maturation in cancerPreprint

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Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

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Current advances in unraveling the function of the Werner syndrome protein

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