Dropout is a problem in lifestyle intervention programs for overweight and obese infertile women: A systematic review
Open accessAbstract
STUDY QUESTION: What are the dropout rates in lifestyle intervention programs (LIPs) for overweight and obese infertile women and can intervention- or patient-related baseline factors associated with dropout be identified in these women? SUMMARY ANSWER: The median dropout rate was 24% in overweight and obese infertile women who participated in a LIP; clinical useful intervention or patient-related factors associated with dropout could not be identified. WHAT IS KNOWN ALREADY: Overweight and obese infertile women might improve their chance of conception when they improve their lifestyle and lose weight. Dropout from LIPs reduces the chance of losing considerable weight and is therefore considered to be an important limiting factor of the success of LIPs. STUDY DESIGN, SIZE, DURATION: This systematic review included 15 studies published between January 1980 and December 2012. PARTICIPANTS/MATERIALS, SETTING, METHODS: The included studies investigated the effect of LIPs for overweight and obese infertile women with infertility. From these studies, dropout rates and intervention- and patient-related baseline factors associated with dropout, as well as weight loss and pregnancy rates, were recorded. MAIN RESULTS AND THE ROLE OF CHANCE: There were 15 studies identified, of which 10 reported dropout rates. The median dropout rate was 24% (range: 0-31%). Four studies reported baseline characteristics of women who dropped out, but modifiable predictors of dropout could not be identified. Weight loss and pregnancy rates were lower in women who dropped out than in women who completed the LIPs. LIMITATIONS, REASONS FOR CAUTION: There were limited numbers of studies investigating patient-related factors associated with dropout. The heterogeneity in the studies precluded us from drawing firm conclusions on the relation between the type of intervention and dropout. WIDER IMPLICATIONS OF THE FINDINGS: Dropout from LIPs is a major drawback because it predisposes to less weight loss and lower pregnancy rates. Identification of predictors of dropout is needed to identify overweight and obese infertile women who are prone for dropout. These women might benefit from extra support and monitoring, to potentially increasing adherence rates, weight loss and pregnancy chances. STUDY FUNDING/COMPETING INTEREST(S): M.A.Q.M. was supported by a research grant from the Dutch Organization for Health Research and Development (ZonMw). The department of obstetrics and gynaecology received research grants from Merck Sharpe and Dohme BV, feering pharmaceuticals, Merck Serono, the Netherlands.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A systematic review of dropout rates in women with infertility, overweight and obesity reported a median dropout rate of 24%.
“A systematic review of dropout rates in women with infertility, overweight and obesity reported a median dropout rate of 24% (Mutsaerts et al., 2013).”
From Improvements in PCOS characteristics and phenotype severity during a randomized controlled lifestyle intervention (2021) · cites this paper as Mutsaerts et al., 2013
Study duration, especially longer lasting lifestyle intervention programmes, seems to be a factor that negatively contributes to compliance; however, other participant-related factors that predict dropout at baseline have not yet been identified.
“Study duration, especially longer lasting lifestyle intervention programmes, seems to be a factor that negatively contributes to compliance; however, other participantrelated factors that predict dropout at baseline have not yet been identified (Mutsaerts et al., 2013).”
From Improvements in PCOS characteristics and phenotype severity during a randomized controlled lifestyle intervention (2021) · cites this paper as Mutsaerts et al., 2013
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Dansinger, M. L., Gleason, J. A., Griffith, J. L., Selker, H. P., & Schaefer, E. J. (2005) · JAMA · doi:10.1001/jama.293.1.43 · Cited by 1,726 · see citing works
Long-term weight-loss maintenance: a meta-analysis of US studies
Anderson, J. W., Konz, E. C., Frederich, R. C., & Wood, C. L. (2001) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.5.579 · Cited by 1,351 · see citing works
Infertility and psychological distress: A critical review of the literature
Greil, A. L. (1997) · Social Science & Medicine · doi:10.1016/s0277-9536(97)00102-0 · Cited by 831 · see citing works
Clark, A. M., Thornley, B., Tomlinson, L., Galletley, C., & Norman, R. J. (1998) · Human Reproduction · doi:10.1093/humrep/13.6.1502 · Cited by 789 · see citing works
Subfecundity in overweight and obese couples
Ramlau‐Hansen, C. H., Thulstrup, A. M., Nohr, E. A., Bonde, J. P., Sørensen, T. I. A., & Olsen, J. (2007) · Human Reproduction · doi:10.1093/humrep/dem035 · Cited by 520 · see citing works
Obesity affects spontaneous pregnancy chances in subfertile, ovulatory women
van der Steeg, J. W., Steures, P., Eijkemans, M. J. C., Habbema, J. D. F., Hompes, P. G. A., Burggraaff, J. M., Oosterhuis, G. J. E., Bossuyt, P. M., van der Veen, F., & Mol, B. W. (2007) · Human Reproduction · doi:10.1093/humrep/dem371 · Cited by 512 · see citing works
Self-citationGesink Law, D. C., Maclehose, R. F., & Longnecker, M. P. (2006) · Human Reproduction · doi:10.1093/humrep/del400 · Cited by 486 · see citing works
Effect of overweight and obesity on assisted reproductive technology—a systematic review
Maheshwari, A., Stofberg, L., & Bhattacharya, S. (2007) · Human Reproduction Update · doi:10.1093/humupd/dmm017 · Cited by 475 · see citing works
Pretreatment predictors of attrition and successful weight management in women
Teixeira, P. J., Going, S. B., Houtkooper, L. B., Cussler, E. C., Metcalfe, L. L., Blew, R. M., Sardinha, L. B., & Lohman, T. G. (2004) · International Journal of Obesity · doi:10.1038/sj.ijo.0802727 · Cited by 371 · see citing works
Female obesity impairs in vitro fertilization outcome without affecting embryo quality
Bellver, J., Ayllón, Y., Ferrando, M., de Melo, M. A. B., Goyri, E., Pellicer, A., Remohi, J. A., & Meseguer, M. (2009) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.12.032 · Cited by 367 · see citing works
Crosignani, P. G. (2003) · Human Reproduction · doi:10.1093/humrep/deg367 · Cited by 359 · see citing works
Tang, T., Glanville, J., Hayden, C. J., White, D., Barth, J. H., & Balen, A. H. (2006) · Human Reproduction · doi:10.1093/humrep/dei311 · Cited by 335 · see citing works
Grave, R. D., Calugi, S., Molinari, E., Petroni, M. L., Bondi, M., Compare, A., Marchesini, G., & QUOVADIS Study Group (2005) · Obesity Research · doi:10.1038/oby.2005.241 · Cited by 306 · see citing works
Huber-Buchholz, M.-M. (1999) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.4.1470 · Cited by 269 · see citing works
Palomba, S., Giallauria, F., Falbo, A., Russo, T., Oppedisano, R., Tolino, A., Colao, A., Vigorito, C., Zullo, F., & Orio, F. (2008) · Human Reproduction · doi:10.1093/humrep/dem391 · Cited by 235 · see citing works
Predictors of drop-out in overweight and obese outpatients
İnelmen, E., Toffanello, E. D., Enzi, G., Gasparini, G., Miotto, F., Sergi, G., & Busetto, L. (2004) · International Journal of Obesity · doi:10.1038/sj.ijo.0802846 · Cited by 198 · see citing works
Effect of body weight reduction on plasma androgens in obese, infertile women
Bates, G. W., & Whitworth, N. S. (1982) · Fertility and Sterility · doi:10.1016/s0015-0282(16)46571-4 · Cited by 186 · see citing works
Jones, F. A., Harris, P. R., Waller, H., & Coggins, A. (2005) · British Journal of Health Psychology · doi:10.1348/135910704x24798 · Cited by 184 · see citing works
Predictors of Attrition in a Large Clinic‐Based Weight‐Loss Program
Honas, J. J., Early, J. L., Frederickson, D. D., & O'Brien, M. S. (2003) · Obesity Research · doi:10.1038/oby.2003.122 · Cited by 175 · see citing works
Infertility: Effects of weight loss on the hormonal profile in obese, infertile women
Hollmann, M., Runnebaum, B., & Gerhard, I. (1996) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a019512 · Cited by 172 · see citing works
Predictors of attrition and weight loss success: Results from a randomized controlled trial
Fabricatore, A. N., Wadden, T. A., Moore, R. H., Butryn, M. L., Heymsfield, S. B., & Nguyen, A. M. (2009) · Behaviour Research and Therapy · doi:10.1016/j.brat.2009.05.004 · Cited by 159 · see citing works
Andersen, P., Seljeflot, I., Abdelnoor, M., Arnesen, H., Dale, P. O., Løvik, A., & Birkeland, K. (1995) · Metabolism · doi:10.1016/0026-0495(95)90118-3 · Cited by 156 · see citing works
Predictors of attrition from behavioral medicine treatments
Davis, M. J., & Addis, M. E. (1999) · Annals of Behavioral Medicine · doi:10.1007/bf02895967 · Cited by 139 · see citing works
Ladson, G., Dodson, W. C., Sweet, S. D., Archibong, A. E., Kunselman, A. R., Demers, L. M., Williams, N. I., Coney, P., & Legro, R. S. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.12.002 · Cited by 138 · see citing works
Clark, M. M., NIAURA, R. S., King, T. K., & Pera, V. (1996) · Addictive Behaviors · doi:10.1016/0306-4603(95)00081-x · Cited by 125 · see citing works
Karimzadeh, M. A., & Javedani, M. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2009.02.078 · Cited by 118 · see citing works
Retention rates and weight loss in a commercial weight loss program
Finley, C. E., Barlow, C. E., Greenway, F. L., Rock, C. L., Rolls, B. J., & Blair, S. N. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803395 · Cited by 117 · see citing works
Palomba, S., Falbo, A., Giallauria, F., Russo, T., Rocca, M., Tolino, A., Zullo, F., & Orio, F. (2010) · Human Reproduction · doi:10.1093/humrep/deq254 · Cited by 111 · see citing works
Harlass, F. E., Plymate, S. R., Fariss, B. L., & Belts, R. P. (1984) · Fertility and Sterility · doi:10.1016/s0015-0282(16)48154-9 · Cited by 103 · see citing works
Pasquali, R., Gambineri, A., Cavazza, C., Gasparini, D. I., Ciampaglia, W., Cognigni, G. E., & Pagotto, U. (2010) · European Journal of Endocrinology · doi:10.1530/eje-10-0692 · Cited by 95 · see citing works
Kuchenbecker, W. K. H., Groen, H., van Asselt, S. J., Bolster, J. H. T., Zwerver, J., Slart, R. H. J., vd Jagt, E. J., Muller Kobold, A. C., Wolffenbuttel, B. H. R., Land, J. A., et al. (2011) · Human Reproduction · doi:10.1093/humrep/der229 · Cited by 76 · see citing works
Self-citationThomson, R. L., Buckley, J. D., Moran, L., Noakes, M., Clifton, P. M., Norman, R. J., & Brinkworth, G. D. (2009) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2009.02177.x · Cited by 59 · see citing works
The false hope syndrome: unrealistic expectations of self-change
Polivy, J. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801705 · Cited by 50 · see citing works
Bützow, T. L., Lehtovirta, M., Siegberg, R., Hovatta, O., Koistinen, R. A., Seppälä, M. T., & Apter, D. L. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.9.6821 · Cited by 50 · see citing works
Qublan, H. S., Yannakoula, E. K., Al-Qudah, M. A., & El-Uri, F. I. (2007) · Saudi Medical Journal · doi:10.15537/1658-3175.4126 · Cited by 40 · see citing works
Messier, V., Hayek, J. E., Karelis, A. D., Messier, L., Doucet, É., Prud’homme, D., RABASA-LHORET, R. P. R., & Strychar, I. M. (2009) · British Journal Of Nutrition · doi:10.1017/s0007114509993023 · Cited by 30 · see citing works
Role for a sense of self-worth in weight-loss treatments: helping patients develop self-efficacy.
Cochrane, G. (2008) · PubMed Central · Cited by 27 · see citing works
Moran, L. J., Noakes, M., Clifton, P. M., & Norman, R. J. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.02.057 · Cited by 17 · see citing works
Effect of short-term diet and exercise on hormone levels and menses in obese, infertile women.
Miller, P. B. W., Forstein, D. A., & Styles, S. (2008) · PubMed · Cited by 14 · see citing works
Aubuchon, M., Laughbaum, N., Poetker, A., Williams, D. B., & Thomas, M. A. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.03.028 · Cited by 12 · see citing works
Flagged first, then by citations
3 of the 43 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Inelmen EM, Toffanello ED, Enzi G, Gasparini G, Miotto F, Sergi G, Busetto L. Predictors of dropout in overweight and obese outpatients . Int J Obes 2005; 29 :122-128.
Cited by
Sorted by citations
Randomized trial of a lifestyle program in obese infertile women
Mutsaerts, M. A. Q., van Oers, A. M., Groen, H., Burggraaff, J. M., Kuchenbecker, W. K. H., Perquin, D. A. M., Koks, C. A. M., van Golde, R., Kaaijk, E. M., Schierbeek, J. M., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1505297 · Cited by 308 · see citing works
Self-citationObesity and reproduction: a committee opinion
Penzias, A. S., Azziz, R., Bendikson, K. A., Falcone, T., Hansen, K. R., Hill, M. J., Jindal, S., Kalra, S. K., Mersereau, J. E., Reindollar, R. H., et al. (2021) · Fertility and Sterility · doi:10.1016/j.fertnstert.2021.08.018 · Cited by 239 · see citing works
Obesity and reproduction: a committee opinion
(2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.08.018 · Cited by 216 · see citing works
Position of the Academy of Nutrition and Dietetics: Obesity, Reproduction, and Pregnancy Outcomes
Stang, J. L., & Huffman, L. G. (2016) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2016.01.008 · Cited by 185 · see citing works
Cooney, L. G., Milman, L. W., Hantsoo, L., Kornfield, S., Sammel, M. D., Allison, K. C., Epperson, C. N., & Dokras, A. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.03.028 · Cited by 117 · see citing works
Factors predictive of drop‐out and weight loss success in weight management of obese patients
Hadžiabdić, M. O., Mucalo, I., Hrabač, P., Matić, T., Rahelić, D., & Božikov, V. (2014) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.12270 · Cited by 111 · see citing works
Reynolds, K. A., Boudoures, A. L., Chi, M. M.-Y., Wang, Q., & Moley, K. H. (2015) · Reproduction Fertility and Development · doi:10.1071/rd14251 · Cited by 104 · see citing works
Lan, L., Harrison, C. L., Misso, M., Hill, B., Teede, H. J., Mol, B. W., & Moran, L. J. (2017) · Human Reproduction · doi:10.1093/humrep/dex241 · Cited by 91 · see citing works
Self-citationBinge eating behaviours and food cravings in women with polycystic ovary syndrome
Jeanes, Y. M., Reeves, S., Gibson, E. L., Piggott, C., May, V. A., & Hart, K. H. (2017) · Appetite · doi:10.1016/j.appet.2016.11.010 · Cited by 85 · see citing works
Gameiro, S., Boivin, J., & Domar, A. (2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.06.015 · Cited by 79 · see citing works
Jiskoot, G., Dietz de Loos, A., Beerthuizen, A., Timman, R., Busschbach, J., & Laven, J. (2020) · PLOS ONE · doi:10.1371/journal.pone.0233876 · Cited by 76 · see citing works
Turner‐McGrievy, G. M., Davidson, C. R., Wingard, E. E., & Billings, D. L. (2014) · Nutrition Research · doi:10.1016/j.nutres.2014.04.011 · Cited by 73 · see citing works
Lie Fong, S., Douma, A., & Verhaeghe, J. (2021) · Journal of Gynecology Obstetrics and Human Reproduction · doi:10.1016/j.jogoh.2020.101894 · Cited by 64 · see citing works
Jiskoot, G., Timman, R., Beerthuizen, A., Dietz de Loos, A., Busschbach, J., & Laven, J. (2020) · Obesity · doi:10.1002/oby.22980 · Cited by 56 · see citing works
Jiskoot, G., Benneheij, S. H., Beerthuizen, A., de Niet, J. E., de Klerk, C., Timman, R., Busschbach, J. J., & Laven, J. S. E. (2017) · Reproductive Health · doi:10.1186/s12978-017-0295-4 · Cited by 50 · see citing works
Health-related knowledge, beliefs and self-efficacy in women with polycystic ovary syndrome
Lin, A. W., Dollahite, J. S., Sobal, J., & Lujan, M. E. (2018) · Human Reproduction · doi:10.1093/humrep/dex351 · Cited by 50 · see citing works
Ponzo, V., Scumaci, E., Goitre, I., Beccuti, G., Benso, A. S., Belcastro, S., Crespi, C., Michieli, F. D., Pellegrini, M., Scuntero, P., et al. (2020) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-020-00990-9 · Cited by 41 · see citing works
Musculoskeletal ageing and primary prevention
Nedergaard, A. F., Henriksen, K., Karsdal, M. A., & Christiansen, C. (2013) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2013.06.001 · Cited by 40 · see citing works
Dietz de Loos, A. L. P., Jiskoot, G., Timman, R., Beerthuizen, A., Busschbach, J. J. V., & Laven, J. S. E. (2021) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2021.05.008 · Cited by 39 · see citing works
The efficacy of morning versus evening exercise for weight loss: A randomized controlled trial
Brooker, P. G., Gomersall, S. R., King, N. A., & LEVERITT, M. D. (2022) · Obesity · doi:10.1002/oby.23605 · Cited by 38 · see citing works
Successful weight loss interventions before in vitro fertilization: fat chance?
Norman, R. J., & Mol, B. W. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.05.029 · Cited by 36 · see citing works
Self-citationWeighing the Impact of Diet and Lifestyle on Female Reproductive Function
Garruti, G., Depalo, R., & Angelis, M. D. (2017) · Current Medicinal Chemistry · doi:10.2174/0929867324666170518101008 · Cited by 34 · see citing works
Metabolic health during a randomized controlled lifestyle intervention in women with PCOS
Dietz de Loos, A., Jiskoot, G., Beerthuizen, A., Busschbach, J., & Laven, J. (2022) · European Journal of Endocrinology · doi:10.1530/eje-21-0669 · Cited by 33 · see citing works
Berks, D., Hoedjes, M., Raat, H., Franx, A., Looman, C. W. N., van Oostwaard, M. F., Papatsonis, D. N. M., Duvekot, J. J., & Steegers, E. A. P. (2018) · Pregnancy Hypertension · doi:10.1016/j.preghy.2018.12.004 · Cited by 34 · see citing works
Liu, Y., & Yin, Z. (2020) · Journal of Medical Internet Research · doi:10.2196/13745 · Cited by 33 · see citing works
Brooker, P. G., Gomersall, S. R., King, N. A., & LEVERITT, M. D. (2019) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2019.100320 · Cited by 32 · see citing works
Perna, S., Spadaccini, D., Riva, A., Allegrini, P., Edera, C., Faliva, M. A., Peroni, G., Naso, M., Nichetti, M., Gozzer, C., et al. (2018) · Endocrine · doi:10.1007/s12020-018-1563-y · Cited by 30 · see citing works
Amini, L., Mojab, F., Jahanfar, S., Sepidarkish, M., Raoofi, Z., & Maleki-Hajiagha, A. (2020) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2019.102245 · Cited by 30 · see citing works
Vitek, W., & Hoeger, K. M. (2022) · Fertility and Sterility · doi:10.1016/j.fertnstert.2022.07.001 · Cited by 30 · see citing works
the LIFEstyle study group, Karsten, M. D. A., van Oers, A. M., Groen, H., Mutsaerts, M. A. Q., van Poppel, M. N. M., Geelen, A., van de Beek, C., Painter, R. C., Mol, B. W., et al. (2018) · European Journal of Nutrition · doi:10.1007/s00394-018-1798-7 · Cited by 29 · see citing works
Self-citationC-reactive protein and ART outcomes: a systematic review
Brouillet, S., Boursier, G., Anav, M., Boissière, B. D. B. D. L., Gala, A., Ferrières-Hoa, A., Touitou, I., & Hamamah, S. (2020) · Human Reproduction Update · doi:10.1093/humupd/dmaa012 · Cited by 28 · see citing works
Jiskoot, G., de Loos, A. D., Timman, R., Beerthuizen, A., Laven, J., & Busschbach, J. (2022) · Journal of Eating Disorders · doi:10.1186/s40337-022-00593-y · Cited by 23 · see citing works
Elías‐López, A. L., Vázquez-Mena, Ó., & Sferruzzi-Perri, A. N. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166802 · Cited by 23 · see citing works
Rosman, L., Armbruster, T., Kyazimzade, S., Tugaoen, Z., Mazzella, A. J., Deyo, Z., Walker, J., Machineni, S., & Gehi, A. K. (2021) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.14188 · Cited by 23 · see citing works
Livingstone, K. M., Celis-Morales, C. A., Macready, A. L., Fallaize, R., Forster, H., Woolhead, C., O’Donovan, C. B., Marsaux, C. F. M., Navas‐Carretero, S., San-Cristóbal, R., et al. (2016) · Public Health Nutrition · doi:10.1017/s1368980016002020 · Cited by 21 · see citing works
Gopalan, V., Yaligar, J., Michael, N., Kaur, K., Anantharaj, R., Verma, S. K., Sadananthan, S. A., Le, G. T. T., Goh, J., & Velan, S. S. (2021) · Bioscience Reports · doi:10.1042/bsr20201707 · Cited by 21 · see citing works
Bouzalmate-Hajjaj, A., Massó Guijarro, P., Khan, K. S., Bueno‐Cavanillas, A., & Ibáñez, N. C. (2022) · Scientific Reports · doi:10.1038/s41598-022-15770-x · Cited by 21 · see citing works
Training in motivational interviewing in obstetrics: a quantitative analytical tool
Lindhardt, C. L., Rubak, S., Mogensen, O. E., Hansen, H. P., Lamont, R., & Jørgensen, J. S. (2014) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.12401 · Cited by 19 · see citing works
The effects of cognitive behavioral therapy in women with polycystic ovary syndrome: A meta-analysis
Tang, R., Yang, J., Yu, Y., & Fang, Y. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.796594 · Cited by 19 · see citing works
Wang, Z., Groen, H., Cantineau, A. E. P., van Elten, T. M., Karsten, M. D. A., van Oers, A. M., Mol, B. W. J., Roseboom, T. J., & Hoek, A. (2021) · Nutrients · doi:10.3390/nu13103425 · Cited by 19 · see citing works
Self-citationBabatunde, O. A., Adams, S. A., Wirth, M. D., Eberth, J. M., Sofge, J., Choi, S. K., Harmon, B. E., Davis, L., Drayton, R., Hurley, T. G., et al. (2017) · Ethnicity & Disease · doi:10.18865/ed.27.3.265 · Cited by 17 · see citing works
Blazey, P., Habibi, A., Hassen, N., Friedman, D., Khan, K. M., & Ardern, C. L. (2023) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/s12966-023-01532-z · Cited by 21 · see citing works
Dupont, C., Aegerter, P., Foucaut, A.-M., Reyre, A., Lhuissier, F., Bourgain, M., Chabbert‐Buffet, N., Cédrin‐Durnerin, I., Selleret, L., Cosson, E., et al. (2020) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-020-2855-9 · Cited by 17 · see citing works
Hamidzadeh, A., Salehin, S., NaseriBooriAbadi, T., Chaman, R., Mogharabian, N., & Keramat, A. (2023) · Middle East Fertility Society Journal · doi:10.1186/s43043-023-00137-7 · Cited by 16 · see citing works
It is not justified to reject fertility treatment based on obesity
Koning, A. M. H., Mol, B. W., & Dondorp, W. (2017) · Human Reproduction Open · doi:10.1093/hropen/hox009 · Cited by 16 · see citing works
Self-citationHow do overweight people dropout of a weight loss diet? A qualitative study
Bazrafkan, L., Choobineh, M. A., Shojaei, M., Bozorgi, A., & Sharifi, M. H. (2021) · BMC Nutrition · doi:10.1186/s40795-021-00480-w · Cited by 14 · see citing works
Timmermans, Y. E. G., van de Kant, K. D. G., Reijnders, D., Kleijkers, L. M. P., Dompeling, E., Kramer, B. W. W., Zimmermann, L. J. I., Steegers‐Theunissen, R. P. M., Spaanderman, M. E. A., & Vreugdenhil, A. C. E. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-030236 · Cited by 14 · see citing works
Best (2017) · doi:10.1093/humrep/dex313 · Cited by 14 · see citing works
Rathod, P., & Yadav, R. P. (2023) · Drug Delivery and Translational Research · doi:10.1007/s13346-023-01404-w · Cited by 11 · see citing works
Malhotra, N., Arora, T., Suri, V., Jena, S. K., Verma, A., Gowri, M., Kapoor, N., Chalga, M. S., Kulkarni, B., & Kamath, M. S. (2023) · Trials · doi:10.1186/s13063-023-07466-y · Cited by 10 · see citing works
Kaiser, K. A., Affuso, O., Desmond, R. A., & Allison, D. B. (2014) · Frontiers in Nutrition · doi:10.3389/fnut.2014.00025 · Cited by 10 · see citing works
Kamińska-Skrzyńska, W., Wiśniewska, K., Okręglicka, K., Pazura, I., & Nitsch-Osuch, A. S. (2023) · Annals of Agricultural and Environmental Medicine · doi:10.26444/aaem/159156 · Cited by 9 · see citing works
Menting, M. D., van de Beek, C., Rönö, K., Hoek, A., Groen, H., Painter, R. C., Girchenko, P. V., Lahti‐Pulkkinen, M., Koivusalo, S. B., Räikkönen, K., et al. (2019) · Scandinavian Journal of Psychology · doi:10.1111/sjop.12575 · Cited by 9 · see citing works
Self-citationBiviá-Roig, G., Blasco-Sanz, R., Boldó-Roda, A., Vara, M. D., Escrivá‐Martínez, T., Herrero, R., Rosa, V. L. L., Baños, R., & Lisón, J. F. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17228312 · Cited by 8 · see citing works
Shashwathi, G., Rao, B. K., Bailey, A., Kumar, P., & Ramachandra, P. (2025) · Brazilian Journal of Physical Therapy · doi:10.1016/j.bjpt.2025.101186 · Cited by 7 · see citing works
Lifestyle treatment in women with polycystic ovary syndrome: predictors of weight loss and dropout
Jiskoot, G., de Loos, A. D., Timman, R., Beerthuizen, A., Laven, J. S. E., & Busschbach, J. J. V. (2022) · Brain and Behavior · doi:10.1002/brb3.2621 · Cited by 6 · see citing works
Abulmeaty, M. M. A. (2016) · Nutrition Clinique et Métabolisme · doi:10.1016/j.nupar.2016.04.001 · Cited by 7 · see citing works
Merius, H. N., & Rohan, A. (2017) · Journal of Community Health Nursing · doi:10.1080/07370016.2017.1369811 · Cited by 7 · see citing works
Scannell, N., Mantzioris, E., Cowan, S., Moran, L., & Villani, A. M. (2025) · Proceedings of The Nutrition Society · doi:10.1017/s0029665126104054 · Cited by 7 · see citing works
Patient and public involvement in lifestyle randomized controlled trials: a systematic review
Bouzalmate-Hajjaj, A., Ibáñez, N. C., Khan, K. S., Bueno‐Cavanillas, A., & Massó Guijarro, P. (2023) · Journal of Public Health · doi:10.1007/s10389-023-02148-0 · Cited by 6 · see citing works
Influence of social determinants on fertility: a critical review
Rico, P.-M. T., & García-Velasco, J. A. (2020) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000673 · Cited by 5 · see citing works
Hoffmann, D. A., & Carels, R. A. (2015) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-015-0214-z · Cited by 5 · see citing works
Medication Adherence Among Women Undergoing Infertility Treatment: A Systematic Review
Mahoney, D. E., Russell, C. L., & Cheng, A. (2018) · International Journal of Women s Health and Reproduction Sciences · doi:10.15296/ijwhr.2019.24 · Cited by 4 · see citing works
Lous, J., & Freund, K. S. (2016) · BMC Family Practice · doi:10.1186/s12875-016-0437-8 · Cited by 5 · see citing works
Preconceptual care for couples seeking fertility treatment, an evidence-based approach
Chronopoulou, E., Seifalian, A., Stephenson, J., Serhal, P. F., Saab, W., & Seshadri, S. (2020) · F&S Reviews · doi:10.1016/j.xfnr.2020.09.001 · Cited by 5 · see citing works
Brooker, P. G., Gomersall, S. R., King, N. A., McMahon, N. F., & LEVERITT, M. D. (2022) · Journal of Behavioral Medicine · doi:10.1007/s10865-022-00370-x · Cited by 4 · see citing works
Jepsen, I. E., Petersen, K. B., Wissing, M. L., Hviid, T. V. F., Macklon, N. S., & Englund, A. L. M. (2023) · Reproductive Female and Child Health · doi:10.1002/rfc2.46 · Cited by 3 · see citing works
Thomson, M., Martin, A., Logue, J., Wells, V., & Simpson, S. A. (2020) · Systematic Reviews · doi:10.1186/s13643-020-01427-1 · Cited by 3 · see citing works
Multimodal Lifestyle Intervention: Outlines and Outcomes
Abulmeaty, M. M. A. (2017) · InTech eBooks · doi:10.5772/66371 · Cited by 2 · see citing works
Koduri, P., Chinta, P., Kunjummen, A. T., Yadav, B., Kapoor, N., Paravathareddy, S., Vimala, & Kamath, M. S. (2024) · Journal of Human Reproductive Sciences · doi:10.4103/jhrs.jhrs_111_24 · Cited by 3 · see citing works
Ann, M., Chinta, P., Koduri, P., Kunjummen, A. T., & Kamath, M. S. (2025) · Journal of Human Reproductive Sciences · doi:10.4103/jhrs.jhrs_173_24 · Cited by 2 · see citing works
Kluge, L., Holter, H., Bergh, C., & Thurin‐Kjellberg, A. (2023) · Reproductive Female and Child Health · doi:10.1002/rfc2.48 · Cited by 2 · see citing works
Guan, M., Li, R., Wang, G., Li, Z., Shen, Q., Peng, E., Qu, J., Lei, J., & Fu, B. (2025) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2025.112200 · Cited by 1 · see citing works
Kumar, P., Pai, P. J., Pallavi, G., Maiya, A. G., & Ramachandra, P. (2016) · International Journal of Infertility & Fetal Medicine · doi:10.5005/jp-journals-10016-1135 · Cited by 1 · see citing works
Lifestyle Intervention for Resumption of Ovulation in Anovulatory Women with Obesity and Infertility
Kuchenbecker, W. K. H., & Hoek, A. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800872-0.00016-0 · Cited by 1 · see citing works
Self-citationPCOS lifestyle program v1Preprint
Jiskoot, G., Laven, J. S. E., Busschbach, J. J. V., de Klerk, C., & de Niet, J. E. (2020) · doi:10.17504/protocols.io.bfq9jmz6
Fertility treatment in obese women
Koning, A. M. H. (2015) · UvA-DARE (University of Amsterdam)
Lieffers, J. R. L. (2016) · UWSpace (University of Waterloo)
Prise en charge de l’infertilité chez la femme obèse
Vincentelli, C., Gaborit, B., Castera, V., Dutour, A., & Courbière, B. (2017) · Obésité · doi:10.1007/s11690-017-0559-8
Lifestyle intervention in obese infertile women
van Oers, A. M. (2017) · University of Groningen research database (University of Groningen / Centre for Information Technology)
Pöyhönen‐Alho, M., Hyrylä, V. V., Tarvainen, M. P., Tikkanen, H. O., Koivusalo, S. B., Koponen, A. S., Peltonen, J. E., & Tiitinen, A. E. (2020) · doi:10.21203/rs.3.rs-18844/v1
Obesity, weight reduction treatment and IVF
Einarsson, S. (2021) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Should women with high body mass index be denied fertility treatments?
Shaikh, S., Srivastava, G., & Homburg, R. (2023) · Human Fertility · doi:10.1080/14647273.2022.2152741
Evaluation of the 10&10,000 Change Challenge Program
McClendon, M., Venkatesh, S., & Faries, M. D. (2025) · Nutrients · doi:10.3390/nu17091494
The management of obesity in assisted reproduction: from individualized to couple-based approach
MARINO, F., CONFORTI, A., Laudisio, D., COLUCCI, R., Varcamonti, L., Alviggi, C., & Colao, A. (2025) · Minerva Obstetrics and Gynecology · doi:10.23736/s2724-606x.25.05810-5
Bélan, M., Giguère-Johnson, M., Carranza‐Mamane, B., Pesant, M.-H., Ainmelk, Y., Langlois, M., Lavoie, H. B., Greenblatt, E. M., Laredo, S., Sagle, M. A., et al. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf660 · Cited by 1 · see citing works
Thomson, M., Martin, A., Logue, J., Wells, V., & Simpson, S. A. (2020) · Figshare · doi:10.6084/m9.figshare.12744319
Blazey, P., Habibi, A., Hassen, N., Friedman, D., Khan, K. M., & Ardern, C. L. (2024) · Figshare · doi:10.6084/m9.figshare.24564275
Blazey, P., Habibi, A., Hassen, N., Friedman, D., Khan, K. M., & Ardern, C. L. (2024) · Figshare · doi:10.6084/m9.figshare.26640109
Thomson, M., Martin, A., Logue, J., Wells, V., & Simpson, S. A. (2020) · Figshare · doi:10.6084/m9.figshare.12744322
Blazey, P., Habibi, A., Hassen, N., Friedman, D., Khan, K. M., & Ardern, C. L. (2024) · Figshare · doi:10.6084/m9.figshare.26640112
Hamidzadeh, A., Salehin, S., NaseriBooriAbadi, T., Chaman, R., Mogharabian, N., & Keramat, A. (2023) · Figshare · doi:10.6084/m9.figshare.22721317
Blazey, P., Habibi, A., Hassen, N., Friedman, D., Khan, K. M., & Ardern, C. L. (2024) · Figshare · doi:10.6084/m9.figshare.26640121
Blazey, P., Habibi, A., Hassen, N., Friedman, D., Khan, K. M., & Ardern, C. L. (2023) · Figshare · doi:10.6084/m9.figshare.24564095
Blazey, P., Habibi, A., Hassen, N., Friedman, D., Khan, K. M., & Ardern, C. L. (2024) · Figshare · doi:10.6084/m9.figshare.26640115
Malhotra, N., Arora, T., Suri, V., Jena, S. K., Verma, A., Gowri, M., Kapoor, N., Chalga, M. S., Kulkarni, B., & Kamath, M. S. (2023) · Figshare · doi:10.6084/m9.figshare.23707022
Blazey, P., Habibi, A., Hassen, N., Friedman, D., Khan, K. M., & Ardern, C. L. (2024) · Figshare · doi:10.6084/m9.figshare.26640124
Within-individual changes in BMI and menstrual irregularity: a cohort study using real-world data
Itoi, S., Sampei, M., Tatsumi, T., Ishida, R., Izumi, G., Osuga, Y., Koga, K., Narumi, S., & Morisaki, N. (2026) · BMC Women s Health · doi:10.1186/s12905-026-04308-2
Lifestyle Intervention in Men With Abnormal Semen Analysis who Desire Fertility: A Feasibility Study
Mohan, H., Niranjan, V. P., Gowri, M. S., Sridhar, R., Chinta, P., Kunjummen, A. T., & Kamath, M. S. (2026) · Andrologia · doi:10.1155/and/1689554
- Authors
- Mutsaerts, M. A. Q., Kuchenbecker, W. K. H., Mol, B. W., Land, J. A., & Hoek, A.
- Affiliations
- University Medical Center Groningen (NL)
- Isala (NL)
- Amsterdam UMC Location University of Amsterdam (NL)
- Corresponding author
- Mutsaerts, M.A.Q.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2013-02-20
- Volume
- 28
- Issue
- 4
- Pages
- 979-986
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2160890483
- Cited by
- 100
- References
- 43
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 7 · 2023: 13 · 2022: 8 · 2021: 8 · 2020: 15 · 2019: 4 · 2018: 6 · 2017: 11 · 2016: 8 · 2015: 5 · 2014: 4 · 2013: 2
- FWCI
- 1.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Human Reproduction (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
- Funders
- ZonMw (50‐50110‐96‐518)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- dropout, lifestyle intervention, overweight, obesity, female infertility, weight loss, pregnancy rate, predictors of dropout, intervention adherence, predictors of treatment response, weight gain during pregnancy, gestational diabetes mellitus, gestational hypertension, gestational diabetes screening
- MeSH terms
- Adult, Female, Humans, Infertility, Female, Obesity, Patient Compliance, Pregnancy, Weight Loss, Pregnancy Rate, Overweight, Weight Reduction Programs
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
