The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
The Induction of Meningeal Inflammation by Components of the Pneumococcal Cell Wall
Abstract
Pneumococcal cell wall induces meningeal inflammation in rabbits injected intracisternally with greater than 10(5) cell equivalents. Both of the major cell wall components, teichoic acid and peptidoglycan, contribute to this inflammatory activity although responses differ depending on the chemical nature, size, and complexity of these fractions. Challenge with teichoic acid (membrane or wall associated) results in greater inflammation at 5 hr than at 24 hr. Degraded teichoic acid is inactive. In contrast, the inflammation caused by whole cell wall or high-molecular-weight peptidoglycan-containing fractions increases in intensity from 5 to 24 hr. Peptidoglycan fractions lose activity at 24 hr when hydrolyzed to disaccharide-stem peptide moieties. Generation of free cell wall components in cerebrospinal fluid as, for example, during treatment with antibiotics that are bacteriolytic as well as bactericidal, could contribute to increased inflammation in the subarachnoid space.
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Cites
Protein Purification by Affinity Chromatography
Cuatrecasas, P. (1970) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63022-4 · Cited by 2,796
Geigy, J. R. (1981) · Medical Entomology and Zoology · Cited by 1,221
A study of the genetic material determining an enzyme activity in Pneumococcus
Lacks, S., & Hotchkiss, R. D. (1960) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(60)90205-5 · Cited by 546
Wicken, A. J., & Knox, K. W. (1975) · Science · doi:10.1126/science.46620 · Cited by 379
Affinity labeling of a phosphorylcholine binding mouse myeloma protein
Chesebro, B., & Metzger, H. (1972) · Biochemistry · doi:10.1021/bi00755a014 · Cited by 344
Mosser, J. L., & Tomasz, A. (1970) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63393-9 · Cited by 300
Self-citationBacterial factors chemotactic for polymorphonuclear leukocytes.
Ward, P. A., Lepow, I. H., & Newman, L. J. (1968) · PubMed · Cited by 297
Dacey, R. G., & Sande, M. A. (1974) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.6.4.437 · Cited by 287
Volanakis, J. E., & Kaplan, M. H. (1974) · PubMed · Cited by 267
Potter, M., & Lieberman, R. (1970) · The Journal of Experimental Medicine · doi:10.1084/jem.132.4.737 · Cited by 245
Cited by
Kadurugamuwa, J. L., & Beveridge, T. J. (1995) · Journal of Bacteriology · doi:10.1128/jb.177.14.3998-4008.1995 · Cited by 678
Bacterial Infection in Chronic Obstructive Pulmonary Disease
Murphy, T. F., & Sethi, S. (1992) · American Review of Respiratory Disease · doi:10.1164/ajrccm/146.4.1067 · Cited by 580
Pathogenesis and Pathophysiology of Pneumococcal Meningitis
Mook-Kanamori, B. B., Geldhoff, M., van der Poll, T., & van de Beek, D. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00008-11 · Cited by 492
Bacteriophage lysins as effective antibacterials
Fischetti, V. A. (2008) · Current Opinion in Microbiology · doi:10.1016/j.mib.2008.09.012 · Cited by 477
Bacteriophage endolysins: A novel anti-infective to control Gram-positive pathogens
Fischetti, V. A. (2010) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2010.04.002 · Cited by 438
Metadata
- Authors
- Tuomanen, E., Liu, H., Hengstler, B., Zak, O., & Tomasz, A.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1985-05-01
- Volume
- 151
- Issue
- 5
- Pages
- 859-868
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2129958874
- Cited by
- 355
- References
- 27
- FWCI
- 6.92
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tuomanen, E., Liu, H., Hengstler, B., Zak, O., & Tomasz, A. (1985). The Induction of Meningeal Inflammation by Components of the Pneumococcal Cell Wall. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/151.5.859
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
