The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Clinical Immunity to Plasmodium falciparum Malaria Is Associated with Serum Antibodies to the 19-kDa C-Terminal Fragment of the Merozoite Surface Antigen, PfMSP-l
Abstract
The development of an effective malaria vaccine depends upon identification of antigens that are targets of protective immune responses. An immunoepidemiologic approach has been used to investigate the relationship between antibody responses to a defined region of the major merozoite surface protein of Plasmodium falciparum (PfMSP-1 19) and resistance to clinical malaria in 2 populations of children from West Africa. After allowing for the confounding effects of age, antibodies to PfMSP-1 19 were shown the provide 40% protection against clinical malaria in children in Sierra Leone. In Gambian children, antibodies to one of the epidermal growth factor-like motifs of PfMSP-1 19 were strongly associated with resistance to both clinical malaria and high levels of parasitemia.
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Cites
Mortality and morbidity from malaria among children in a rural area of The Gambia, West Africa
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Self-citationSiddiqui, W. A., Tam, L. Q., Kramer, K. J., Hui, G. S., Case, S. E., Yamaga, K. M., Chang, S. P., Chan, E. B., & Kan, S. C. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.9.3014 · Cited by 304
Antibodies inhibit the protease-mediated processing of a malaria merozoite surface protein.
Blackman, M. J., Scott-Finnigan, T. J., Shai, S., & Holder, A. A. (1994) · The Journal of experimental medicine · doi:10.1084/jem.180.1.389 · Cited by 265
Self-citationRILEY, E. M., ALLEN, S. J., WHEELER, J. G., BLACKMAN, M. J., BENNETT, S., TAKACS, B., SCHONFELD, H. ‐., HOLDER, A. A., & GREENWOOD, B. M. (1992) · Parasite Immunology · doi:10.1111/j.1365-3024.1992.tb00471.x · Cited by 239
Self-citationPerrin, L. H., Merkli, B., Loche, M., Chizzolini, C., Smart, J., & Richle, R. (1984) · The Journal of experimental medicine · doi:10.1084/jem.160.2.441 · Cited by 186
Immunization against malaria with a recombinant protein
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Self-citationMahanty, S., Mollis, S. N., Ravichandran, M., Abrams, J. S., Kumaraswami, V., Jayaraman, K., Ottesen, E. A., & Nutman, T. B. (1996) · Journal of Infectious Diseases · doi:10.1093/infdis/173.3.769 · Cited by 165
Egan, A. F., Chappel, J. A., Burghaus, P. A., Morris, J., McBride, J. S., Holder, A. A., Kaslow, D. C., & Riley, E. M. (1995) · Infection and Immunity · doi:10.1128/iai.63.2.456-466.1995 · Cited by 150
Self-citationChappel, J. A., & Holder, A. A. (1993) · Molecular and Biochemical Parasitology · doi:10.1016/0166-6851(93)90141-j · Cited by 142
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Cited by
Immune effector mechanisms in malaria
MARSH, K., & KINYANJUI, S. (2006) · Parasite Immunology · doi:10.1111/j.1365-3024.2006.00808.x · Cited by 419
ANDERSON, T. J. C., SU, X.-Z., BOCKARIE, M., LAGOG, M., & DAY, K. P. (1999) · Parasitology · doi:10.1017/s0031182099004552 · Cited by 355
Fowkes, F. J. I., Richards, J. S., Simpson, J. A., & Beeson, J. G. (2010) · PLoS Medicine · doi:10.1371/journal.pmed.1000218 · Cited by 345
Antibody-based therapies for malaria
Pleass, R. J., & Holder, A. A. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1267 · Cited by 182
Self-citationStanisic, D. I., Fowkes, F. J. I., Koinari, M., Javati, S., Lin, E., Kiniboro, B., Richards, J. S., Robinson, L. J., Schofield, L., Kazura, J. W., et al. (2015) · Infection and Immunity · doi:10.1128/iai.02398-14 · Cited by 151
Metadata
- Authors
- Egan, A. F., Morris, J., Barnish, G., Allen, S., Greenwood, B. M., Kaslow, D. C., Holder, A. A., & Riley, E. M.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1996-03-01
- Volume
- 173
- Issue
- 3
- Pages
- 765-768
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2168202434
- Cited by
- 309
- References
- 13
- FWCI
- 20.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Clinical Immunity to Plasmodium falciparum Malaria Is Associated with Serum Antibodies to the 19-kDa C-Terminal Fragment of the Merozoite Surface Antigen, PfMSP-l. https://app.cochat.ai/papers/10.1093/infdis/173.3.765
- The paper
- Egan, A. F., Morris, J., Barnish, G., Allen, S., Greenwood, B. M., Kaslow, D. C., Holder, A. A., & Riley, E. M. (1996). Clinical Immunity to Plasmodium falciparum Malaria Is Associated with Serum Antibodies to the 19-kDa C-Terminal Fragment of the Merozoite Surface Antigen, PfMSP-l. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/173.3.765
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
