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. Plasma levels of soluble CD14 independently predict mortality in HIV infection.
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BACKGROUND: Chronic human immunodeficiency virus (HIV) infection is associated with intestinal permeability and microbial translocation that contributes to systemic immune activation, which is an independent predictor of HIV disease progression. The association of microbial translocation with clinical outcome remains unknown. METHODS: This nested case-control study included 74 subjects who died, 120 of whom developed cardiovascular disease and 81 of whom developed AIDS during the Strategies for Management of Anti-Retroviral Therapy (SMART) study with matched control subjects. Intestinal fatty acid binding protein (I-FABP), lipopolysaccharide (LPS), soluble CD14 (sCD14), endotoxin core antibody (EndoCAb), and 16S ribosomal DNA (rDNA) were measured in baseline plasma samples. RESULTS: Subjects with the highest quartile of sCD14 levels had a 6-fold higher risk of death than did those in the lowest quartile (95% confidence interval, 2.2-16.1; P<.001), with minimal change after adjustment for inflammatory markers, CD4(+) T cell count, and HIV RNA level. No other marker was significantly associated with clinical outcomes. I-FABP, LPS, and sCD14 were increased and EndoCAb was decreased in study subjects, compared with healthy volunteers. sCD14 level correlated with levels of IL-6, C-reactive protein, serum amyloid A and D-dimer. CONCLUSIONS: sCD14, a marker of monocyte response to LPS, is an independent predictor of mortality in HIV infection. Therapeutic attenuation of innate immune activation may improve survival in patients with HIV infection.
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“However, as among those without HIV infection, a likely driving force behind this vulnerability to injury is chronic inflammation (67–69).”
From HIV and Aging: State of Knowledge and Areas of Critical Need for Research. A Report to the NIH Office of AIDS Research by the HIV and Aging Working Group (2012) · cites this paper as [69]
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Microbial translocation is a cause of systemic immune activation in chronic HIV infection
Brenchley, J. M., Price, D. A., Schacker, T. W., Asher, T. E., Silvestri, G., Rao, S., Kazzaz, Z., Bornstein, E., Lambotte, O., Altmann, D., et al. (2006) · Nature Medicine · doi:10.1038/nm1511 · Cited by 3,559
Self-citationCD4+ Count–Guided Interruption of Antiretroviral Treatment
The Strategies for Management of Antiretroviral Therapy (SMART) Study Group (2006) · New England Journal of Medicine · doi:10.1056/nejmoa062360 · Cited by 2,250
Brenchley, J. M., Schacker, T. W., Ruff, L. E., Price, D. A., Taylor, J. H., Beilman, G. J., Nguyen, P. L., Khoruts, A., Larson, M. C., Haase, A. T., et al. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20040874 · Cited by 1,836
Self-citation. Inflammatory and coagulation biomarkers and mortality in patients with HIV infection.
Kuller, L. H., Tracy, R., Belloso, W., Wit, S. D., Drummond, F., Lane, H. C., Ledergerber, B., Lundgren, J., Neuhaus, J., Nixon, D., et al. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050203 · Cited by 1,617
Self-citationVeazey, R. S., DeMaria, M. A., Chalifoux, L. V., Shvetz, D. E., Pauley, D. R., Knight, H., Rosenzweig, M., Johnson, R. P., Desrosiers, R. C., & Lackner, A. A. (1998) · Science · doi:10.1126/science.280.5362.427 · Cited by 1,404
LPS, TLR4 and infectious disease diversity
Miller, S., Ernst, R. K., & Bader, M. W. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1068 · Cited by 1,059
Giorgi, J. V., Hultin, L. E., McKeating, J. A., Johnson, T. D., Owens, B. M., Jacobson, L. P., Shih, R., Lewis, J., Wiley, D. J., Phair, J. P., et al. (1999) · The Journal of Infectious Diseases · doi:10.1086/314660 · Cited by 1,032
Hunt, P. W., Martin, J. N., Sinclair, E., Bredt, B. M., Hagos, E., Lampiris, H. W., & Deeks, S. G. (2003) · The Journal of Infectious Diseases · doi:10.1086/374786 · Cited by 852
Self-citationDeeks, S. G., Ramirez, C. M., Liu, L., Guo, H., Gascon, R., Narváez, A. B., Hunt, P. W., Martin, J. N., Kahn, J. S., Levy, J. A., et al. (2004) · Blood · doi:10.1182/blood-2003-09-3333 · Cited by 803
Self-citationJiang, W., Lederman, M. M., Hunt, P. W., Sieg, S. F., Haley, K. P., Rodriguez, B. A., LANDAY, A. L., Martin, J. N., Sinclair, E., Asher, A. I., et al. (2009) · The Journal of Infectious Diseases · doi:10.1086/597476 · Cited by 598
Self-citation
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Sorted by citations
Items 501–600 of 1,000
Asowata, O. E., Singh, A., Ngoepe, A., Herbert, N. G., Fardoos, R., Reddy, K., Zungu, Y., Nene, F., Mthabela, N., Ramjit, D., et al. (2021) · JCI Insight · doi:10.1172/jci.insight.146162 · Cited by 22
Massanella, M., Ouchi, D., Marfil, S., Llibre, J. M., Puertas, M. C., Buzón, M. J., Richman, D. D., Orna, E., Stevenson, M., Gatell, J. M., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0114142 · Cited by 23
Markers of Inflammation and Mortality in a Cohort of Patients With Alcohol Dependence
Fuster, D., Sanvisens, A., Bolao, F., Zuluaga, P., Rivas, I., Tor, J., & Muga, R. (2015) · Medicine · doi:10.1097/md.0000000000000607 · Cited by 23
Distortion of memory Vδ2 γδ T cells contributes to immune dysfunction in chronic HIV infection
Li, Z., Jiao, Y., Hu, Y., Cui, L., Chen, D., Wu, H., Zhang, J., & He, W. (2014) · Cellular and Molecular Immunology · doi:10.1038/cmi.2014.77 · Cited by 24
Singh, M., Singh, P., Vaira, D., Amand, M., Rahmouni, S., & Moutschen, M. P. (2014) · Immunology · doi:10.1111/imm.12246 · Cited by 22
Cavaleiro, R., Rego, R. T., Foxall, R. B., Soares, R. S., Baptista, A. P., Gómes, P., Valadas, E., Victorino, R. M. M., & Sousa, A. E. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit085 · Cited by 25
Breed, M. W., Elser, S. E., Torben, W., Jordan, A. P. O., Aye, P. P., Midkiff, C. C., Schiro, F. R., Sugimoto, C., Alvarez-Hernandez, X., Blair, R. V., et al. (2015) · Journal of Virology · doi:10.1128/jvi.01134-15 · Cited by 23
Kasang, C., Kalluvya, S. E., Majinge, C., Kongola, G. W., Mlewa, M., Massawe, I., Kabyemera, R., Magambo, K. A., Ulmer, A., Klinker, H., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0146678 · Cited by 24
Cytomegalovirus and paediatric HIV infection
Slyker, J. A. (2016) · Journal of Virus Eradication · doi:10.1016/s2055-6640(20)30873-6 · Cited by 26
Shive, C. L., Judge, C. J., Clagett, B. M., Kalayjian, R. C., Osborn, M. K., Sherman, K. E., Fichtenbaum, C. J., Gandhi, R. T., Kang, M., Popkin, D. L., et al. (2017) · Vaccine · doi:10.1016/j.vaccine.2017.12.018 · Cited by 22
Reid, M. J. A., Ma, Y., Scherzer, R., Price, J. C., French, A. L., Huhn, G. D., Plankey, M. W., Peters, M. G., Grünfeld, C., & Tien, P. C. (2018) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix688 · Cited by 23
Parisi, S. G., Andreis, S., Mengoli, C., Menegotto, N., Cavinato, S., Scaggiante, R., Andreoni, M., Palù, G., Basso, M., & Cattelan, A. M. (2018) · Medical Microbiology and Immunology · doi:10.1007/s00430-018-0538-1 · Cited by 23
Missailidis, C., Sørensen, N., Ashenafi, S., Amogne, W., Kassa, E., Bekele, A., Getachew, M., Gebreselassie, N. G., Aseffa, A., Aderaye, G., et al. (2019) · Nutrients · doi:10.3390/nu11071675 · Cited by 23
Dual Antiretroviral Therapy—All Quiet Beneath the Surface?
van Welzen, B. J., Oomen, P. G. A., & Hoepelman, A. I. M. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.637910 · Cited by 23
Taiwo, B., Matining, R. M., Zheng, L., Lederman, M. M., Rinaldo, C. R., Kim, P. S., Berzins, B. I., Kuritzkes, D. R., Jennings, A., Eron, J. J., et al. (2013) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkt120 · Cited by 22
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Imamichi, H., & Lane, H. C. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis238 · Cited by 22
Hel, Z., Xu, J., Denning, W. L., Helton, E. S., Huijbregts, R. P. H., Heath, S. L., Overton, E. T., Christmann, B. S., Elson, C. O., Goepfert, P., et al. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006087 · Cited by 22
Yadav, A., Kossenkov, A. V., Knecht, V. R., Showe, L. C., Ratcliffe, S. J., Montaner, L. J., Tebas, P., & Collman, R. G. (2019) · Pathogens and Immunity · doi:10.20411/pai.v4i2.336 · Cited by 22
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Blanco, J. R., Negredo, E., Bernal, E., & Blanco, J. (2020) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2021.1848546 · Cited by 22
Caetano, D. G., Alves, M. R., Hottz, E. D., Villela, L. M., Cardoso, S. W., Hoagland, B., Grinsztejn, B. G. J., Veloso, V. G., Morgado, M. G., Bozza, P. T., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-10330-9 · Cited by 19
Perkins, M. R., Bartha, I., Timmer, J. K., Liebner, J. C., Wollinsky, D., Günthard, H. F., Hauser, C., Bernasconi, E., Hoffmann, M., Calmy, A., et al. (2015) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiv089 · Cited by 22
Self-citationImmune Suppression by Myeloid Cells in HIV Infection: New Targets for Immunotherapy
Mehraj, V., Jenabian, M.-A., Vyboh, K., & Routy, J. (2014) · The Open AIDS Journal · doi:10.2174/1874613601408010066 · Cited by 22
The gut and oral microbiome in HIV disease: a workshop report
Moyes, D. L., Saxena, D. B., John, M., & Malamud, D. (2016) · Oral Diseases · doi:10.1111/odi.12415 · Cited by 23
Francesco, D. D., Wit, F. W. N. M., Cole, J. H., Kootstra, N. A., Winston, A., Sabin, C. A., Underwood, J., van Zoest, R. A., Schouten, J., Kooij, K. W., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191791 · Cited by 23
Decreased bone turnover in HIV-infected children on antiretroviral therapy
Shiau, S., Yin, M. T., Strehlau, R., Patel, F., Mbete, N., Kuhn, L., Coovadia, A. H., & Arpadi, S. M. (2018) · Archives of Osteoporosis · doi:10.1007/s11657-018-0452-6 · Cited by 22
Coindre, S., Tchitchek, N., Alaoui, L., Vaslin, B., Bourgeois, C., Goujard, C., Lécuroux, C., Bruhns, P., Grand, R. L., Beignon, A., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02677 · Cited by 22
Malo, A. I., Rull, A., Girona, J., Domingo, P., Fuertes-Martín, R., Amigó, N., Rodríguez-Borjabad, C., Martínez-Micaelo, N., Leal, M., Peraire, J., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9051344 · Cited by 23
Gut microbiome and cardiometabolic comorbidities in people living with HIV
Trøseid, M., Nielsen, S. D., & Vujkovic-Cvijin, I. (2024) · Microbiome · doi:10.1186/s40168-024-01815-y · Cited by 25
Sex Differences in the Treatment of HIV
Cohn, J., Ake, J. A., Moorhouse, M. A., & Godfrey, C. C. (2020) · Current HIV/AIDS Reports · doi:10.1007/s11904-020-00499-x · Cited by 22
Naidoo, K. K., Ndumnego, O. C., Ismail, N., Dong, K. L., & Ndung’u, T. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.738743 · Cited by 21
Littlefield, K. M., Schneider, J. M., Neff, C. P., Soesanto, V., Siebert, J., Nusbacher, N. M., Moreno-Huizar, N., Cartwright, I. M., Armstrong, A. J. S., Colgen, S. P., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1072720 · Cited by 22
Kim, H. J., Jang, J., Na, K., Lee, E. H., Gu, H.-J., Lim, Y. H., Joo, S.-A., Baek, S. E., Roh, J. Y., Maeng, H., et al. (2024) · Experimental & Molecular Medicine · doi:10.1038/s12276-024-01225-y · Cited by 21
Patro, S. C., Pal, S., Bi, Y., Lynn, K., Mounzer, K., Kostman, J. R., Davuluri, R. V., & Montaner, L. J. (2014) · Journal of Virology · doi:10.1128/jvi.02382-14 · Cited by 20
The role of T cells in the development of cardiovascular disease in HIV-infected patients
Krikke, M., van Lelyveld, S. F. L., Tesselaar, K., Arends, J. E., Hoepelman, I. M., & Visseren, F. L. J. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.08.054 · Cited by 21
Ipp, H., Zemlin, A. E., Glashoff, R. H., van Wyk, J., Vanker, N., Reid, T., & Bekker, L. (2012) · Journal of Clinical Immunology · doi:10.1007/s10875-012-9832-7 · Cited by 21
Alcohol use predicts elevation in inflammatory marker soluble CD14 in men living with HIV
Monnig, M. A., Kahler, C. W., Cioe, P. A., Tucker, L. D., Monti, P. M., Mayer, K. H., & Ramratnam, B. (2016) · AIDS Care · doi:10.1080/09540121.2016.1189497 · Cited by 22
Sunil, M., Nigalye, M., Somasunderam, A., Martinez, M. L., Yu, X., Arduino, R. C., Utay, N. S., & Bell, T. K. (2016) · AIDS Research and Human Retroviruses · doi:10.1089/aid.2016.0007 · Cited by 20
Atherosclerotic Cardiovascular Disease and Anti-Retroviral Therapy
Kaplan‐Lewis, E., Aberg, J. A., & Lee, M.-K. (2016) · Current HIV/AIDS Reports · doi:10.1007/s11904-016-0331-y · Cited by 21
Hearps, A. C., Agius, P. A., Zhou, J., Brunt, S. J., Chachage, M., Angelovich, T. A., Cameron, P. U., Giles, M., Price, P., Elliott, J., et al. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00731 · Cited by 23
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Head, B. M., Mao, R. T., Keynan, Y., & Rueda, Z. V. (2019) · PLoS ONE · doi:10.1371/journal.pone.0226347 · Cited by 21
Bailin, S. S., McGinnis, K. A., McDonnell, W. J., So‐Armah, K., Wellons, M., Tracy, R. P., Doyle, M. F., Mallal, S. A., Justice, A. C., Freiberg, M. S., et al. (2020) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaa069 · Cited by 21
Galvão-Lima, L. J., Espíndola, M. S., Soares, L. S., Zambuzi, F. A., Cacemiro, M. D. C., Fontanari, C., Bóllela, V. R., & Frantz, F. G. (2016) · The Brazilian Journal of Infectious Diseases · doi:10.1016/j.bjid.2016.10.004 · Cited by 21
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Costiniuk, C. T., & Jenabian, M.-A. (2014) · AIDS Patient Care and STDs · doi:10.1089/apc.2014.0173 · Cited by 21
Erlandson, K. M., Jiang, Y., Debanne, S. M., & McComsey, G. A. (2015) · AIDS Research and Human Retroviruses · doi:10.1089/aid.2015.0191 · Cited by 20
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Romero-Sánchez, M. C., Machmach, K., González‐Serna, A., Genebat, M., Pulido, I., García-García, M., Álvarez‐Ríos, A. I., Ferrando‐Martínez, S., Ruíz-Mateos, E., & Leal, M. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01406-12 · Cited by 20
PrayGod, G., Blevins, M. L., Woodd, S., Rehman, A. M., Jeremiah, K., Friis, H., Kelly, P. M., Changalucha, J. M., Heimburger, D. C., Filteau, S., et al. (2016) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2015.221 · Cited by 20
den Dries, L. V., Claassen, M. A. A., Groothuismink, Z. M. A., Gorp, E. C. M. V., & Boonstra, A. (2017) · Virology · doi:10.1016/j.virol.2017.06.014 · Cited by 20
Social Isolation Is Linked to Inflammation in Aging People With HIV and Uninfected Individuals
Ellis, R. J., Iudicello, J., Sun-Suslow, N., Grelotti, D. J., Cherner, M., Morgan, E. E., Letendre, S. L., & Heaton, R. K. (2020) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000002596 · Cited by 21
ApoA-I mimetics reduce systemic and gut inflammation in chronic treated HIV
Δάσκου, Μ., Mu, W., Sharma, M. B., Vasilopoulos, H., Heymans, R., Ritou, E., Rezek, V. K., Hamid, P., Kossyvakis, A., Roy, S. S., et al. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010160 · Cited by 20
Canipe, A., Chidumayo, T., Blevins, M. L., Bestawros, M. T., Bala, J., Kelly, P. M., Filteau, S., Shepherd, B. E., Heimburger, D. C., & Koethe, J. R. (2014) · BMC Infectious Diseases · doi:10.1186/1471-2334-14-521 · Cited by 20
Wang, W., Wu, F.-X., Cong, Z., Liu, K., Qin, C., & Wei, Q. (2014) · Journal of Immunology Research · doi:10.1155/2014/387950 · Cited by 19
Changes in Immune Activation During Pregnancy and the Postpartum Period in Treated HIV Infection
Schnittman, S. R., Byakwaga, H., Boum, Y., Kabakyenga, J. K., Matthews, L. T., Burdo, T. H., Huang, Y., Tracy, R. P., Haberer, J. E., Kembabazi, A., et al. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofab245 · Cited by 19
Villar, S. S., López‐Huertas, M. R., Jiménez, D., Galera, C., Martínez‐Sanz, J., Moreno, E., Muriel, A., Gutiérrez, F., Busca, C., Portilla, J., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.848630 · Cited by 19
HMOX1 genetic polymorphisms and outcomes in infectious disease: A systematic review
Hamilton, F., Somers, J., Mitchell, R. E., Ghazal, P., & Timpson, N. J. (2022) · PLoS ONE · doi:10.1371/journal.pone.0267399 · Cited by 18
So‐Armah, K., Quinn, E. K., Cheng, D. M., Tracy, R. P., Baker, J. V., Samet, J. H., & Freiberg, M. S. (2013) · BMC Infectious Diseases · doi:10.1186/1471-2334-13-399 · Cited by 19
Torres, B., Guardo, A. C., Leal, L., León, A., Lucero, C., Álvarez-Martínez, M. J., Martínez, M. J., Vilà, J., Martínez‐Rebollar, M., Gonzalez‐Cordón, A., et al. (2014) · Journal of the International AIDS Society · doi:10.7448/ias.17.1.19246 · Cited by 21
Subbarao, S., Wilkinson, K. A., van Halsema, C. L., Rao, S. S., Boyles, T. H., Utay, N. S., Wilkinson, R. J., & Meintjes, G. (2015) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000763 · Cited by 19
Valiathan, R., & Asthana, D. (2016) · Immunobiology · doi:10.1016/j.imbio.2016.01.002 · Cited by 20
Metabolic and Cardiovascular Complications in HIV/HCV-Co-infected Patients
Bedimo, R. G., & Abodunde, O. A. (2016) · Current HIV/AIDS Reports · doi:10.1007/s11904-016-0333-9 · Cited by 19
Increased Immune Activation and Exhaustion in HIV-infected Youth
Eckard, A. R., Rosebush, J., Lee, S. T., O’Riordan, M. A., Habib, J. G., Daniels, J. E., Labbato, D. E., Uribe-Leitz, M., Chahroudi, A., & McComsey, G. A. (2016) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000001326 · Cited by 18
Subclinical atherosclerosis in low Framingham risk HIV patients
León, R., Reus, S., López, N., Portilla, I., Sánchez–Payá, J., Giner, L., Boix, V., Merino, E., Torrús, D., Moreno, Ó., et al. (2017) · European Journal of Clinical Investigation · doi:10.1111/eci.12780 · Cited by 19
Belmonti, S., Lombardi, F., Quirós-Roldán, E., Latini, A., Castagna, A., Borghetti, A., Baldin, G., Ciccullo, A., Cauda, R., Luca, A. D., et al. (2018) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dky125 · Cited by 19
Le, C. N., Britto, P., Brummel, S. S., Hoffman, R. M., Li, J. Z., Flynn, P. M., Taha, T. E., Coletti, A., Fowler, M. G., Bosch, R. J., et al. (2019) · AIDS · doi:10.1097/qad.0000000000002334 · Cited by 19
Blood Bacterial Profiles Associated With Human Immunodeficiency Virus Infection and Immune Recovery
Villar, S. S., Sánchez-Carrillo, S., Talavera-Rodríguez, A., Lelouvier, B., Gutiérrez, C., Vallejo, A., Servant, F., Bernardino, J. I., Estrada, V., Madrid, N., et al. (2020) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaa379 · Cited by 24
Temu, T. M., Polyak, S. J., Zifodya, J. S., Wanjalla, C. N., Koethe, J. R., Masyuko, S. J., Nyabiage, J., Kinuthia, J., Gervassi, A. L., Oyugi, J. O., et al. (2020) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofaa425 · Cited by 19
Wong, M. E., Johnson, C. J., Hearps, A. C., & Jaworowski, A. (2021) · Journal of Virology · doi:10.1128/jvi.00227-21 · Cited by 19
Immune Modulators of HIV Infection: The Role of Reactive Oxygen Species
Salmen, S., & Berrueta, L. (2012) · Journal of Clinical & Cellular Immunology · doi:10.4172/2155-9899.1000121 · Cited by 19
Balagopal, A., Gupte, N., Shivakoti, R., Cox, A. L., Yang, W.-T., Berendes, S., Mwelase, N., Kanyama, C., Pillay, S., Samaneka, W. P., et al. (2016) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofw118 · Cited by 19
Spadaro, F., Cecchetti, S., & Fantuzzi, L. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18071390 · Cited by 20
NK Cells, Monocytes and Macrophages in HIV-1 Control: Impact of Innate Immune Responses
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Zhao, H., Feng, A., Luo, D., Wu, H., Zhang, G., Zhang, L., Yuan, J., Lin, Y., Li, L., & Zou, H. (2023) · Journal of Medical Virology · doi:10.1002/jmv.28674 · Cited by 18
The human microbiome and gut–liver axis in people living with HIV
Duarte, M., Tien, P. C., Somsouk, M., & Price, J. C. (2023) · Current HIV/AIDS Reports · doi:10.1007/s11904-023-00657-x · Cited by 20
Авдонин, П. П., Blinova, M. S., Генералова, Г. А., Emirova, K., & Avdonin, P. V. (2023) · Biomolecules · doi:10.3390/biom14010039 · Cited by 19
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Jones, R., Robinson, A. T., Beach, L. B., Lindsey, M. L., Kirabo, A., Hinton, A. O., Jr., Erlandson, K. M., & Jenkins, N. D. M. (2024) · Circulation Research · doi:10.1161/circresaha.124.323975 · Cited by 23
Monnig, M. A., Kahler, C. W., Cioe, P. A., Monti, P. M., Mayer, K. H., Pantalone, D. W., Cohen, R. A., & Ramratnam, B. (2017) · Microorganisms · doi:10.3390/microorganisms5040064 · Cited by 21
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Lake, J. E., & Clark, J. L. (2018) · AIDS · doi:10.1097/qad.0000000000002095 · Cited by 18
Monocyte activation, HIV, and cognitive performance in East Africa
Muñoz‐Nevárez, L. A., Imp, B. M., Eller, M. A., Kiweewa, F., Maswai, J., Polyak, C. S., Olwenyi, O. A., Allen, I. E., Rono, E., Milanini, B., et al. (2019) · Journal of NeuroVirology · doi:10.1007/s13365-019-00794-3 · Cited by 18
Zhang, M., Song, T., Zheng, H., Wang, X., Lu, Y., Zhang, H., Li, T., Pang, W., & Zheng, Y. (2019) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2019.047 · Cited by 18
Shete, A., Bangar, S. D., Dhamanage, A., Kulkarni, S., Ghate, M., Sangle, S. A., Medhe, U., Verma, V. K., Rajan, S., Hattori, T., et al. (2020) · AIDS Research and Therapy · doi:10.1186/s12981-020-00298-9 · Cited by 18
Temu, T. M., Zifodya, J. S., Polyak, S. J., Wagoner, J., Wanjalla, C. N., Masyuko, S. J., Nyabiage, J., Kinuthia, J., Bloomfield, G. S., Page, S. T., et al. (2020) · AIDS · doi:10.1097/qad.0000000000002729 · Cited by 18
Funderburg, N., Boucher, M., Sattar, A., Kulkarni, M., Labbato, D. E., Kinley, B., & McComsey, G. A. (2016) · Pathogens and Immunity · doi:10.20411/pai.v1i1.124 · Cited by 18
Lok, J. J., Hunt, P. W., Collier, A. C., Benson, C. A., Witt, M. D., Luque, A. E., Deeks, S. G., & Bosch, R. J. (2013) · AIDS · doi:10.1097/qad.0b013e32836191b1 · Cited by 17
Self-citationMelvin, A. J., Warshaw, M. G., Compagnucci, A., Saïdi, Y., Harrison, L., Turkova, A., Tudor‐Williams, G., & and the PENPACT-1 (PENTA 9/PACTG 390/ANRS 103) Study Team (2017) · Journal of the Pediatric Infectious Diseases Society · doi:10.1093/jpids/pix050 · Cited by 17
Vadaq, N., Zhang, Y., Vos, W. A. J. W., Groenendijk, A. L., Blaauw, M. J. T., van Eekeren, L. E., Cleophas, M. C. P., de Wijer, L. V., dos Santos, J. C., Gasem, M. H., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.166166 · Cited by 17
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Fernandez-Botrán, R., Joshi‐Barve, S., Ghare, S. S., Barve, S. S., Young, M., Plankey, M. W., & Bordón, J. (2014) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2014.0006 · Cited by 17
Chirouze, C., Journot, V., Moing, V. L., Raffi, F., Piroth, L., Reigadas, S., Cassuto, J., Chêne, G., Leport, C., & Hoen, B. (2014) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000416 · Cited by 17
Espíndola, M. S., de Lima, L. J. G., Soares, L. S., Cacemiro, M. D. C., Zambuzi, F. A., Gomes, M. D. S., do Amaral, L. R., Bóllela, V. R., Martins‐Filho, O. A., & Frantz, F. G. (2015) · PLoS ONE · doi:10.1371/journal.pone.0145261 · Cited by 17
Voeght, A. D., Martens, H., Renard, C., Vaira, D., Debruche, M., Simonet, J., Geenen, V. G., Moutschen, M. P., & Darcis, G. (2017) · PLoS ONE · doi:10.1371/journal.pone.0185761 · Cited by 17
Shivakoti, R., Ewald, E. R., Gupte, N., Yang, W.-T., Kanyama, C., Cardoso, S. W., Santos, B. R., Supparatpinyo, K., Badal‐Faesen, S., Lama, J. R., et al. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2018.05.014 · Cited by 17
McIntosh, R. C., Paul, R. H., Ndhlovu, L. C., Hidalgo, M., Lobo, J. D., Walker, M., Shikuma, C. M., & Kallianpur, K. J. (2018) · Journal of NeuroVirology · doi:10.1007/s13365-018-0658-9 · Cited by 17
Premeaux, T. A., Javandel, S., Hosaka, K. R. J., Greene, M. L., Therrien, N. R., Allen, I. E., Corley, M. J., Valcour, V., & Ndhlovu, L. C. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01321 · Cited by 17
Han, W. M., Ubolyam, S., Apornpong, T., Kerr, S. J., Hansasuta, P., Gatechompol, S., Maek-a-nantawat, W., Ruxrungtham, K., Phanuphak, P., Ananworanich, J., et al. (2020) · Journal of Virus Eradication · doi:10.1016/j.jve.2020.100005 · Cited by 17
Self-citationApolipoprotein A-I mimetics attenuate macrophage activation in chronic treated HIV
Mu, W., Sharma, M. B., Heymans, R., Ritou, E., Rezek, V. K., Hamid, P., Kossyvakis, A., Roy, S. S., Grijalva, V. R., Chattopadhyay, A., et al. (2020) · AIDS · doi:10.1097/qad.0000000000002785 · Cited by 17
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Swaminathan, S., Hu, Z., Rupert, A. W., Higgins, J. M., Dewar, R. L., Stevens, R. A., Chen, Q., Rehm, C. A., Metcalf, J. A., Baseler, M., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098989 · Cited by 17
Heart–Lung Interaction via Infection
Morris, A. (2014) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201306-157mg · Cited by 18
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Meng, Q., Sayın, I., Canaday, D. H., Mayanja‐Kizza, H., Baseke, J., & Toossi, Z. (2016) · PLoS ONE · doi:10.1371/journal.pone.0166954 · Cited by 17
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Sinha, A., Ma, Y., Scherzer, R., Rahalkar, S., Neilan, B. D., Crane, H. M., Drozd, D. R., Martin, J. N., Deeks, S. G., Hunt, P. W., et al. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.118.011037 · Cited by 17
Self-citationInsulin resistance and intestinal integrity in children with and without HIV infection in Uganda
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Hunt, P. W. (2016) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiw264 · Cited by 17
Kgoadi, K., Bajpai, P., Ibegbu, C., Dkhar, H. K., Enriquez, A. B., Dawa, S., Cribbs, S. K., & Rengarajan, J. (2025) · Nature Communications · doi:10.1038/s41467-025-57668-y · Cited by 18
Metadata
- Authors
- Sandler, N. G., Wand, H., Roque, A., Law, M., Nason, M. C., Nixon, D. E., Pedersen, C., Ruxrungtham, K., Lewin, S. R., Emery, S., Neaton, J. D., Brenchley, J. M., Deeks, S. G., Sereti, I., & Douek, D. C.
- Affiliations
- UNSW Sydney (AU)
- National Institutes of Health (US)
- Virginia Commonwealth University (US)
- University of Southern Denmark (DK)
- Chulalongkorn University (TH)
- Burnet Institute (AU)
- University of Minnesota (US)
- San Francisco General Hospital (US)
- ORCID
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-03-15
- Volume
- 203
- Issue
- 6
- Pages
- 780-790
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- PMC
- PMC3071127
- OpenAlex
- W2098152094
- Cited by
- 1,106
- References
- 50
- Citations by year
- 2026: 32 · 2025: 31 · 2024: 59 · 2023: 48 · 2022: 67 · 2021: 70 · 2020: 76 · 2019: 70 · 2018: 69 · 2017: 83 · 2016: 107 · 2015: 97 · 2014: 111 · 2013: 93 · 2012: 65
- FWCI
- 37.22
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Journal of Infectious Diseases (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion)
- Funders
- National Center for Genetic Engineering and Biotechnology
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases (AI 76174, P01AI076174)
- Topics
- Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
- Health Sciences › Medicine › Infectious Diseases › HIV-related health complications and treatments
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- soluble CD14, HIV infection, mortality prediction, microbial translocation, intestinal permeability, lipopolysaccharide, endotoxin core antibody, intestinal fatty acid binding protein, cardiovascular disease, AIDS, innate immune activation, SMART trial, prognostic factors
- MeSH terms
- Adult, Cause of Death, Humans, Lipopolysaccharides, Male, Middle Aged, RNA, Viral, Biomarkers, CD4-Positive T-Lymphocytes, HIV Infections, Logistic Models, Case-Control Studies, Lipopolysaccharide Receptors, Fatty Acid-Binding Proteins, Young Adult
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