Cited by 123Reproductive tract infections researchGut microbiota and healthCervical Cancer and HPV Research

The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.

Extravaginal reservoirs of vaginal bacteria as risk factors for incident bacterial vaginosis.

Open access

Marrazzo, Jeanne M., Fiedler, Tina L., Srinivasan, Sujatha, Thomas, Katherine K., Liu, Congzhou, Ko, Daisy, Xie, Hu, Saracino, Misty, Fredricks, David N.·2012·The Journal of Infectious Diseases

DOI 10.1093/infdis/jis242PMC PMC3415820

Open this paper in CoChat — free account Open PDF

Abstract

BACKGROUND: Bacterial vaginosis (BV) represents shifts in microbiota from Lactobacillus spp. to diverse anaerobes. Although antibiotics relieve symptoms and temporarily eradicate BV-associated bacteria (BVAB), BV usually recurs. We investigated the role of extravaginal BVAB reservoirs in recurrence. METHODS: Risks for BV acquisition over the course of 1 year were defined. DNA in vaginal, anal, and oral swab samples from enrollment was subjected to quantitative polymerase chain reaction assays targeting 16S ribosomal RNA genes of Gardnerella vaginalis, Lactobacillus crispatus, BVAB1, BVAB2, BVAB3, Megasphaera spp., Lactobacillus jensenii, and Leptotrichia/Sneathia spp. A case-control approach analyzed BVAB detection at enrollment for case patients (BV acquisition) versus controls (none). RESULTS: Of 239 women enrolled without BV, 199 were seen in follow-up, and 40 experienced BV; 15 had all samples for analysis. Detection of G. vaginalis in oral cavity or anal samples and Leptotrichia/Sneathia spp. in anal samples was more common at enrollment among case patients, who also had higher concentrations of these bacteria and Megasphaera relative to 30 controls at each site. In contrast, L. crispatus was detected more frequently in anal samples among controls. CONCLUSIONS: Women who acquire BV are more likely have previous colonization of extravaginal reservoirs with some BVAB, and less likely to have L. crispatus, suggesting that BVAB may be acquired vaginally from extravaginal reservoirs.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1093/infdis/jis242

Cites

36 of 36 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
Dominguez-Bello, M. G., Costello, E. K., Contreras, M., Magris, M., Hidalgo, G., Fierer, N., & Knight, R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002601107 · Cited by 4,774
Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation
Nugent, R. P., Krohn, M. A., & Hillier, S. L. (1991) · Journal of Clinical Microbiology · doi:10.1128/jcm.29.2.297-301.1991 · Cited by 3,332
Nonspecific vaginitis
Amsel, R., Totten, P. A., Spiegel, C. A., Chen, K. C. S., Eschenbach, D. A., & Holmes, K. K. (1983) · The American Journal of Medicine · doi:10.1016/0002-9343(83)91112-9 · Cited by 2,412
Defining the healthy “core microbiome” of oral microbial communities
Zaura, E., Keijser, B. J., Huse, S. M., & Crielaard, W. (2009) · BMC Microbiology · doi:10.1186/1471-2180-9-259 · Cited by 1,323
High Recurrence Rates of Bacterial Vaginosis over the Course of 12 Months after Oral Metronidazole Therapy and Factors Associated with Recurrence
Bradshaw, C. S., Morton, A. N., Hocking, J. S., Garland, S. M., Morris, M. B., Moss, L. M., Horvath, L. B., Kuzevska, I., & Fairley, C. K. (2006) · The Journal of Infectious Diseases · doi:10.1086/503780 · Cited by 793
The prevalence of bacterial vaginosis in the United States, 2001–2004; associations with symptoms, sexual behaviors, and reproductive health.
Koumans, E. H., Sternberg, M., Bruce, C., McQuillan, G., Kendrick, J., Sutton, M., & Markowitz, L. E. (2007) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e318074e565 · Cited by 761
Bacterial vaginosis as a risk factor for preterm delivery: A meta-analysis
Leitich, H., Bodner‐Adler, B., Brunbauer, M., Kaider, A., Egarter, C., & Husslein, P. W. (2003) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2003.339 · Cited by 735
Bacterial vaginosis and HIV acquisition: A meta-analysis of published studies
Atashili, J., Poole, C., Ndumbe, P. M., Adimora, A. A., & Smith, J. S. (2008) · AIDS · doi:10.1097/qad.0b013e3283021a37 · Cited by 706
Bacterial diversity within the human subgingival crevice
Kroes, I., Lepp, P. W., & Relman, D. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.25.14547 · Cited by 606
Temporal Variability of Human Vaginal Bacteria and Relationship with Bacterial Vaginosis
Srinivasan, S., Liu, C., Mitchell, C. M., Fiedler, T. L., Thomas, K. K., Agnew, K. J., Marrazzo, J. M., & Fredricks, D. N. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010197 · Cited by 471

Show all 36 references

Research works printed but not linked: 2

Hillier, 2008, Bacterial vaginosis, 737
Srinavasan, 2008, Human vaginal bacterial community dynamics assessed by quantitative PCR and relationship with bacterial vaginosis

Sorted by citations

Sexually Transmitted Infections Treatment Guidelines, 2021
Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., & Bolan, G. A. (2021) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr7004a1 · Cited by 3,018
Sexually Transmitted Diseases Treatment Guidelines, 2010
Workowski, K., & BOLAN, G. A. (2011) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2011.04.006 · Cited by 2,074
The Vaginal Microbiota: What Have We Learned after a Decade of Molecular Characterization?
van de Wijgert, J. H. H. M., Borgdorff, H., Verhelst, R., Crucitti, T., Francis, S. C., Verstraelen, H., & Jespers, V. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105998 · Cited by 480
Interplay between the temporal dynamics of the vaginal microbiota and human papillomavirus detection
Brotman, R. M., Shardell, M. D., Gajer, P., Tracy, J. K., Zenilman, J. M., Ravel, J., & Gravitt, P. E. (2014) · Journal of Infectious Diseases · doi:10.1093/infdis/jiu330 · Cited by 411
Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis
Aldunate, M., Srbinovski, D., Hearps, A. C., Latham, C. F., Ramsland, P. A., Gugasyan, R., Cone, R. A., & Tachedjian, G. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00164 · Cited by 395
Randomized Trial of Lactin-V to Prevent Recurrence of Bacterial Vaginosis
Cohen, C. R., Wierzbicki, M. R., French, A. L., Morris, S., Newmann, S., Reno, H., Green, L., Miller, S., Powell, J., Parks, T., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa1915254 · Cited by 377
Cervicovaginal Microbiota and Reproductive Health: The Virtue of Simplicity
Anahtar, M. N., Gootenberg, D. B., Mitchell, C. M., & Kwon, D. S. (2018) · Cell Host & Microbe · doi:10.1016/j.chom.2018.01.013 · Cited by 302
Vaginal Microbiome and Its Relationship to Behavior, Sexual Health, and Sexually Transmitted Diseases
Lewis, F. M. T., Bernstein, K. T., & Aral, S. O. (2017) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000001932 · Cited by 248
Women and Their Microbes: The Unexpected Friendship
Younes, J. A., Lievens, E., Hummelen, R., van der Westen, R., Reid, G., & Petrova, M. (2017) · Trends in Microbiology · doi:10.1016/j.tim.2017.07.008 · Cited by 243
Bacterial Vaginosis: What Do We Currently Know?
Chacra, L. A., Fenollar, F., & Diop, K. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.672429 · Cited by 251
Reviewing the Composition of Vaginal Microbiota: Inclusion of Nutrition and Probiotic Factors in the Maintenance of Eubiosis
Barrientos‐Durán, A., Fuentes, A. P., de Salazar, A., Plaza‐Díaz, J., & García, F. (2020) · Nutrients · doi:10.3390/nu12020419 · Cited by 188
The Vaginal Microbiome: Current Understanding and Future Directions
Martin, D. H., & Marrazzo, J. M. (2016) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiw184 · Cited by 163
Vaginal Microbiota
Mendling, W. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-31248-4_6 · Cited by 161
Vaginal microbiome and cervical cancer
Kyrgiou, M., & Moscicki, A. (2022) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2022.03.005 · Cited by 172
Healthy Vaginal Microbiota and Influence of Probiotics Across the Female Life Span
Lehtoranta, L., Ala‐Jaakkola, R., Laitila, A., & Maukonen, J. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.819958 · Cited by 146
Comparative genomics of Lactobacillus crispatus suggests novel mechanisms for the competitive exclusion of Gardnerella vaginalis
Ojala, T., Kankainen, M., Castro, J., Cerca, N., Edelman, S., Westerlund‐Wikström, B., Paulin, L. G., Holm, L., & Auvinen, P. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-1070 · Cited by 131
Bacterial vaginosis: a review of approaches to treatment and prevention
Abbe, C., & Mitchell, C. M. (2023) · Frontiers in Reproductive Health · doi:10.3389/frph.2023.1100029 · Cited by 138
Anaerobes and Bacterial Vaginosis in Pregnancy: Virulence Factors Contributing to Vaginal Colonisation
Africa, C. W. J., Nel, J., & Stemmet, M. (2014) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph110706979 · Cited by 123
Identification, quantification and subtyping of Gardnerella vaginalis in noncultured clinical vaginal samples by quantitative PCR
Balashov, S. V., Mordechai, E., Adelson, M. E., & Gygax, S. E. (2013) · Journal of Medical Microbiology · doi:10.1099/jmm.0.066407-0 · Cited by 118
Host and Microbiome Interplay Shapes the Vaginal Microenvironment
Kwon, M. S., & Lee, H. K. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.919728 · Cited by 116
Promising Prebiotic Candidate Established by Evaluation of Lactitol, Lactulose, Raffinose, and Oligofructose for Maintenance of a Lactobacillus-Dominated Vaginal Microbiota
Collins, S. L., McMillan, A., Seney, S. L., van der Veer, C., Kort, R., Sumarah, M. W., & Reid, G. (2017) · Applied and Environmental Microbiology · doi:10.1128/aem.02200-17 · Cited by 107
Associations between the vaginal microbiome and Candida colonization in women of reproductive age
Tortelli, B. A., Lewis, W. G., Allsworth, J. E., Member-Meneh, N., Foster, L. R., Reno, H., Peipert, J. F., Fay, J. C., & Lewis, A. L. (2019) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2019.10.008 · Cited by 96
Incident Bacterial Vaginosis (BV) in Women Who Have Sex With Women Is Associated With Behaviors That Suggest Sexual Transmission of BV
Vodstrcil, L. A., Walker, S. M., Hocking, J. S., Law, M. G., Forcey, D. S., Fehler, G., Bilardi, J., Chen, M. Y., Fethers, K. A., Fairley, C. K., et al. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu1130 · Cited by 95
Association between obesity and bacterial vaginosis as assessed by Nugent score
Brookheart, R. T., Lewis, W. G., Peipert, J. F., Lewis, A. L., & Allsworth, J. E. (2019) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2019.01.229 · Cited by 85
Combined oral and topical antimicrobial therapy for male partners of women with bacterial vaginosis: Acceptability, tolerability and impact on the genital microbiota of couples - A pilot study
Plummer, E. L., Vodstrcil, L. A., Danielewski, J., Murray, G. L., Fairley, C. K., Garland, S. M., Hocking, J. S., Tabrizi, S. N., & Bradshaw, C. S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190199 · Cited by 70
Bacterial Vaginosis–Associated Bacteria in Men
Manhart, L. E., Khosropour, C. M., Liu, C., Gillespie, C. W., Depner, K., Fiedler, T. L., Marrazzo, J. M., & Fredricks, D. N. (2013) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000000054 · Cited by 72
Bacterial vaginosis
Bradshaw, C. S., Plummer, E. L., Muzny, C. A., Mitchell, C. M., Fredricks, D. N., Herbst‐Kralovetz, M. M., & Vodstrcil, L. A. (2025) · Nature Reviews Disease Primers · doi:10.1038/s41572-025-00626-1 · Cited by 72
Identification and characterization of NanH2 and NanH3, enzymes responsible for sialidase activity in the vaginal bacterium Gardnerella vaginalis
Robinson, L. S., Schwebke, J. R., Lewis, W. G., & Lewis, A. L. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.006221 · Cited by 64
Human Microbiota Network: Unveiling Potential Crosstalk between the Different Microbiota Ecosystems and Their Role in Health and Disease
Martínez, J. E., Vargas, A., Pérez, T., Encío, I., Cabello-Olmo, M., & Barajas, M. (2021) · Nutrients · doi:10.3390/nu13092905 · Cited by 69
Sneathia: an emerging pathogen in female reproductive disease and adverse perinatal outcomes
Theis, K. R., Сергеевна, Ф. В., Romero, R. J., Borisov, A. B., Winters, A. D., Galaz, J., & Gomez‐Lopez, N. (2021) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2021.1905606 · Cited by 65
Salivary bacterial shifts in oral leukoplakia resemble the dysbiotic oral cancer bacteriome
Gopinath, D., Menon, R. K., Wie, C. C., Banerjee, M., Panda, S., Mandal, D. P., Behera, P. K., Roychoudhury, S., Kheur, S. M., Botelho, M. G., et al. (2020) · Journal of Oral Microbiology · doi:10.1080/20002297.2020.1857998 · Cited by 53
The Penile Microbiota in Uncircumcised and Circumcised Men: Relationships With HIV and Human Papillomavirus Infections and Cervicovaginal Microbiota
Onywera, H., Williamson, A., Ponomarenko, J. V., & Meiring, T. L. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.00383 · Cited by 52
Recent progress in understanding the epidemiology of bacterial vaginosis
Kenyon, C. R., & Osbak, K. K. (2014) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000112 · Cited by 49
Mageeibacillus indolicus gen. nov., sp. nov.: A novel bacterium isolated from the female genital tract
Austin, M. N., Rabe, L. K., Srinivasan, S., Fredricks, D. N., Wiesenfeld, H. C., & Hillier, S. L. (2014) · Anaerobe · doi:10.1016/j.anaerobe.2014.12.003 · Cited by 48
Gardnerella vaginalis: Still a Prime Suspect in the Pathogenesis of Bacterial Vaginosis
Muzny, C. A., & Schwebke, J. R. (2013) · Current Infectious Disease Reports · doi:10.1007/s11908-013-0318-4 · Cited by 47
Connecting the Dots: Translating the Vaginal Microbiome Into a Drug
Lagenaur, L. A., Hemmerling, A., Chiu, C. Y., Miller, S. A., Lee, P. P., Cohen, C. R., & Parks, T. P. (2020) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaa676 · Cited by 45
The Role of Fatty Acid Metabolites in Vaginal Health and Disease: Application to Candidiasis
Baldewijns, S., Sillen, M., Palmans, I., Vandecruys, P., Van Dijck, P., & Demuyser, L. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.705779 · Cited by 44
Incubation period and risk factors support sexual transmission of bacterial vaginosis in women who have sex with women.
Muzny, C. A., Lensing, S. Y., Aaron, K. J., & Schwebke, J. R. (2019) · Sexually Transmitted Infections · doi:10.1136/sextrans-2018-053824 · Cited by 43
Characterization of the vaginal microflora in health and disease.
Datcu, R. (2014) · PubMed · Cited by 42
Lactobacillus Probiotics Improve Vaginal Dysbiosis in Asymptomatic Women
Ansari, A., Son, D., Hur, Y. M., Park, S., You, Y., Kim, S. M., Lee, G., Kang, S., Chung, Y., Lim, S., et al. (2023) · Nutrients · doi:10.3390/nu15081862 · Cited by 39
Oral Intake of Lactobacilli Can Be Helpful in Symptomatic Bacterial Vaginosis: A Randomized Clinical Study
Reznichenko, H., Henyk, N. I., MALYUK, V. V., Khyzhnyak, T., Tynna, Y., Filipiuk, I., Veresnyuk, N. S., Zubrytska, L., Quintens, J., Richir, K., et al. (2020) · Journal of Lower Genital Tract Disease · doi:10.1097/lgt.0000000000000518 · Cited by 43
Life History Recorded in the Vagino-Cervical Microbiome Along with Multi-Omes
Jie, Z., Chen, C., Hao, L., Li, F., Song, L., Zhang, X., Zhu, J., Tian, L., Tong, X., Cai, K., et al. (2021) · Genomics Proteomics & Bioinformatics · doi:10.1016/j.gpb.2021.01.005 · Cited by 36
The role of the bacterial microbiota on reproductive and pregnancy health
Nelson, D. B., Rockwell, L. C., Prioleau, M. D., & Goetzl, L. M. (2016) · Anaerobe · doi:10.1016/j.anaerobe.2016.09.001 · Cited by 35
Pre-Pregnancy Diet and Vaginal Environment in Caucasian Pregnant Women: An Exploratory Study
Dall’Asta, M., Laghi, L., Morselli, S., Re, M. C., Zagonari, S., Patuelli, G., Foschi, C., Pedna, M. F., Sambri, V., Marangoni, A., et al. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.702370 · Cited by 36
Insights into the CRISPR/Cas system of Gardnerella vaginalis
Pleckaityte, M., Zilnyte, M., & Zvirbliene, A. (2012) · BMC Microbiology · doi:10.1186/1471-2180-12-301 · Cited by 33
Behavioural and medical predictors of bacterial vaginosis recurrence among female sex workers: longitudinal analysis from a randomized controlled trial
Guédou, F. A., Damme, L. V., Deese, J., Crucitti, T., Becker, M., Mirembe, F. M., Solomon, S., & Alary, M. (2013) · BMC Infectious Diseases · doi:10.1186/1471-2334-13-208 · Cited by 34
Association of Sexual Debut in Adolescents With Microbiota and Inflammatory Markers
Jespers, V., Hardy, L., Buyze, J., Loos, J., Buvé, A., & Crucitti, T. (2016) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000001468 · Cited by 30
The Female Reproductive Tract Microbiome—Implications for Gynecologic Cancers and Personalized Medicine
Rizzo, A. E., Gordon, J., Berard, A. R., Burgener, A., & Avril, S. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11060546 · Cited by 30
Utilization of molecular methods to identify prognostic markers for recurrent bacterial vaginosis
Hilbert, D. W., Smith, W. L., Paulish, T., Chadwick, S. G., Toner, G., Mordechai, E., Adelson, M. E., Sobel, J. D., & Gygax, S. E. (2016) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2016.07.003 · Cited by 31
Megasphaera lornae sp. nov., Megasphaera hutchinsoni sp. nov., and Megasphaera vaginalis sp. nov.: novel bacteria isolated from the female genital tract
Srinivasan, S., Beamer, M. A., Fiedler, T. L., Austin, M. N., Sizova, M. V., Strenk, S. M., Agnew, K. J., Gowda, G. A. N., Raftery, D., Epstein, S. S., et al. (2019) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijsem.0.004702 · Cited by 30
Gut and oral microbiota in gynecological cancers: interaction, mechanism, and therapeutic value
Wu, J., Li, J., Yan, M., & Xiang, Z. (2024) · npj Biofilms and Microbiomes · doi:10.1038/s41522-024-00577-7 · Cited by 28
Vaginal sialoglycan foraging by Gardnerella vaginalis : mucus barriers as a meal for unwelcome guests?
Agarwal, K., & Lewis, A. L. (2021) · Glycobiology · doi:10.1093/glycob/cwab024 · Cited by 28
A Prospective Cohort Study of the Association Between Body Mass Index and Incident Bacterial Vaginosis
Lokken, E. M., Richardson, B. A., Kinuthia, J., Mwinyikai, K., Abdalla, A., Jaoko, W. G., Mandaliya, K. N., Shafi, J., & McClelland, R. S. (2018) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000000905 · Cited by 28
Characterization of the Vaginal Microbiota among Sexual Risk Behavior Groups of Women with Bacterial Vaginosis
Muzny, C. A., Sunesara, I., Kumar, R., Mena, L. A., Griswold, M. E., Martin, D. H., Lefkowitz, E. J., & Schwebke, J. R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080254 · Cited by 27
Bacterial Vaginosis and Post-Operative Pelvic Infections
Ziogou, A., Ziogos, E., Giannakodimos, I., Giannakodimos, A., Sifakis, S., Ιωάννου, Π., & Tsiodras, S. (2023) · Healthcare · doi:10.3390/healthcare11091218 · Cited by 27
Prevalence of bacterial vaginosis and factors associated among women who have sex with women
Ignácio, M. A. D. O., Andrade, J., de Freitas, A. P. F., Pinto, G. V. D. S., da Silva, M. G., & Duarte, M. T. C. (2018) · Revista Latino-Americana de Enfermagem · doi:10.1590/1518-8345.2491.3077 · Cited by 26
Prevalence of bacterial vaginosis and associated factors among pregnant women attending at Bugando Medical Centre, Mwanza, Tanzania
Massinde, A. N., Shayo, P. A., Kihunrwa, A., Mirambo, M., Rumanyika, R. N., Ngwalida, N., Gumodoka, B., Jeremiah, K., & Magoma, M. (2012) · Tanzania journal of health research/Tanzania Journal of Health Research · doi:10.4314/thrb.v14i3.3 · Cited by 24
SARS-Cov2 enables anaerobic bacteria (Prevotella, et al) to colonize the lungs disrupting homeostasis, causing long-drawn chronic symptoms, and acute severe symptoms (ARDS, septic shock, clots, arterial stroke) which finds resonance, with key differences, in the ‘forgotten disease’ Lemierre Syndrome, enabled by Epstein Barr VirusPreprint
Chakraborty, S. (2020) · doi:10.31219/osf.io/usztn · Cited by 23
Cervicovaginal microbiome dynamics after taking oral probiotics
Chen, C., Hao, L., Zhang, Z., Tian, L., Zhang, X., Zhu, J., Jie, Z., Tong, X., Xiao, L., Zhang, T., et al. (2021) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2021.03.019 · Cited by 23
Vaginal Biofilms and Bacterial Vaginosis: Of Mice and Women
Marrazzo, J. M. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit050 · Cited by 20
Microbial Pathogens Linked to Vaginal Microbiome Dysbiosis and Therapeutic Tools for Their Treatment
Borrego-Ruiz, A., & Borrego, J. J. (2025) · Acta Microbiologica Hellenica · doi:10.3390/amh70020019 · Cited by 23
Gardnerella vaginalis as a Rare Cause of Prosthetic Joint Infection
Hoarau, G., Bernard, S., Pavèse, P., Saragaglia, D., Croizé, J., & Maurin, M. (2012) · Journal of Clinical Microbiology · doi:10.1128/jcm.01969-12 · Cited by 18
Distinct Ecological Niche of Anal, Oral, and Cervical Mucosal Microbiomes in Adolescent Women.
Smith, B. C., Zolnik, C. P., Usyk, M., Chen, Z., Kaiser, K., Nucci-Sack, A. T., Peake, K., Díaz, Á., Shankar, V., Strickler, H. D., et al. (2016) · PubMed Central · Cited by 17
Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men
Fredricks, D. N., Plantinga, A., Srinivasan, S., Oot, A. R., Wiser, A. H., Fiedler, T. L., Proll, S. C., Wu, M. C., & Marrazzo, J. M. (2020) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaa233 · Cited by 18
Recovery of Saccharomyces cerevisiae CNCM I-3856 in Vaginal Samples of Healthy Women after Oral Administration
Decherf, A. C., Dehay, E., Boyer, M., Clément‐Ziza, M., Rodriguez, B., & Legrain–Raspaud, S. (2020) · Nutrients · doi:10.3390/nu12082211 · Cited by 16
Sneathia vaginalis sp. nov. (Fusobacteriales, Leptotrichiaceae) as a replacement of the species ‘Sneathia amnii’ Harwich et al. 2012 and ‘Leptotrichia amnionii’ Shukla et al. 2002, and emended description of Sneathia Collins et al. 2001
Eisenberg, T., Gronow, S., Falgenhauer, J. C., Imirzalioglu, C., Mühldorfer, K., Rau, J., Blom, J., Fawzy, A., Glaeser, S. P., & Kämpfer, P. (2019) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijsem.0.004663 · Cited by 16
Bacterial Vaginosis-Associated Bacteria
Margolis, E. B., & Fredricks, D. N. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397169-2.00083-4 · Cited by 17
Bacterial Vaginosis and Sexually Transmitted Infections in an HIV-Positive Cohort
Nava-Memije, K., Hernández‐Cortez, C., Ruíz‐González, V., Saldaña-Juárez, C. A., Medina-Islas, Y., Dueñas-Domínguez, R. A., & Aguilera‐Arreola, M. G. (2021) · Frontiers in Reproductive Health · doi:10.3389/frph.2021.660672 · Cited by 16
Normal and abnormal vaginal microbiota
Mendling, W. (2016) · Journal of Laboratory Medicine · doi:10.1515/labmed-2016-0011 · Cited by 13
Bacterial Vaginosis: Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/028, June 2023)
Farr, A., Swidsinski, S., Surbek, D., Tirri, B. F., Willinger, B., Hoyme, U. B., Walter, G., Reckel-Botzem, I., & Mendling, W. (2023) · Geburtshilfe und Frauenheilkunde · doi:10.1055/a-2169-8539 · Cited by 13
Managing Recurrent Bacterial Vaginosis: Insights for Busy Providers
Marshall, A. O. (2015) · Sexual Medicine Reviews · doi:10.1002/smrj.45 · Cited by 12
How does gut microbiota affect the vaginitis axis? The mediating role of plasma metabolites
Li, M., Zhang, Q., Wu, T., Ma, L., Hu, D., Yuan, Z., Wang, S., Luo, A., & Zhang, J. (2024) · Microbiology Spectrum · doi:10.1128/spectrum.02263-24 · Cited by 11
The Application of Molecular Methods Towards an Understanding of the Role of the Vaginal Microbiome in Health and Disease
Borgogna, J.-L. C., & Yeoman, C. J. (2017) · Methods in microbiology · doi:10.1016/bs.mim.2017.08.003 · Cited by 9
The detection of microorganisms related to urethritis from the oral cavity of male patients with urethritis
Le, P. T., Hamasuna, R., Matsumoto, M., Furubayashi, K., Hatanaka, M., Kawai, S., Yamaguchi, T., Uehara, K., Murakami, N., Yoshioka, M., et al. (2017) · Journal of Infection and Chemotherapy · doi:10.1016/j.jiac.2017.06.011 · Cited by 9
Insights into Women's health: Exploring the vaginal microbiome, quorum sensing dynamics, and therapeutic potential of quorum sensing quenchers
Núño, K., Jensen, A. S., O’Connor, G., Houston, T., Dikici, E., Zingg, J. M., Deo, S. K., & Daunert, S. (2024) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2024.101304 · Cited by 9
Semen Bacterial Concentrations and HIV-1 RNA Shedding Among HIV-1–Seropositive Kenyan Men
Korhonen, C. J., Srinivasan, S., Huang, D., Ko, D. L., Sanders, E. J., Peshu, N. M., Krieger, J. N., MULLER, C. H., Coombs, R. W., Fredricks, D. N., et al. (2016) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000001244 · Cited by 7
FDG PET/CT of Gardnerella vaginalis Infection
Foret, T., Dhomps, A., Dauwalder, O., Skanjeti, A., & Tordo, J. (2019) · Clinical Nuclear Medicine · doi:10.1097/rlu.0000000000002623 · Cited by 7
Bacterial Vaginosis
Marrazzo, J. M., & Hillier, S. L. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-391059-2.00018-8 · Cited by 7
Determinants of Vaginal Microbiome Stability and Homeostasis
Borrego-Ruiz, A., & Borrego, J. J. (2025) · Biocell · doi:10.32604/biocell.2025.066108 · Cited by 8
Vaginale Mikrobiota – ein Update
Mendling, W. (2015) · Der Gynäkologe · doi:10.1007/s00129-015-3743-7 · Cited by 6
Risk and protective factors associated with BV chronicity among women in Rakai, Uganda
Thoma, M. E., Brotman, R. M., Gray, R. H., Sewankambo, N. K., & Wawer, M. J. (2019) · Sexually Transmitted Infections · doi:10.1136/sextrans-2019-054145 · Cited by 6
CE
McElroy, K. G., Chung, S.-Y., & Regan, M. B. (2017) · AJN American Journal of Nursing · doi:10.1097/01.naj.0000520917.73358.99 · Cited by 7
Gardnerella vaginalis: genotypic and phenotypic diversity, virulence factors and role in the pathogenesis of bacterial vaginosis
Krysanova, A. А. (2019) · Journal of obstetrics and women s diseases · doi:10.17816/jowd68159-68 · Cited by 6
STIs Among Women Who Have Sex with Women
Gorgos, L. M., & Marrazzo, J. M. (2017) · Springer eBooks · doi:10.1007/978-3-319-56694-8_13 · Cited by 5
Factors Associated with Vaginal Lactobacillus Predominance Among African American Women Early in Pregnancy
Wright, M. L., Dunlop, A. L., Amore, A. D., Mitchell, R., Wissel, E. F., & Corwin, E. J. (2021) · Journal of Women s Health · doi:10.1089/jwh.2021.0148 · Cited by 5
Parental microbiome programming of early-life neurodevelopment: multi-niche contributions through the microbiome–gut–brain axis
Skrabulyte-Barbulescu, J., Yassin, L. K., Almazrouei, S., Alkuwaiti, S. H., Almarzooqi, S., AlNuaimi, F., Alketbi, S., Nakhal, M. M., Rutkowska-Gauvry, P., Matar, S. A., et al. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2673888 · Cited by 6
Recurrent bacterial vaginosis
Pyatkova, N. P. (2024) · Health and Ecology Issues · doi:10.51523/2708-6011.2024-21-2-01 · Cited by 4
Correction: Characterization of the Vaginal Microbiota among Sexual Risk Behavior Groups of Women with Bacterial Vaginosis
Muzny, C. A., Sunesara, I., Kumar, R., Mena, L. A., Griswold, M. E., Martin, D. H., Lefkowitz, E. J., & Schwebke, J. R. (2013) · PLoS ONE · doi:10.1371/annotation/f7674ab1-fbd5-4293-ad2c-d1a795962e8b · Cited by 4
Efficacy of fermented foods for the prevention and treatment of bacterial vaginosis and vulvovaginal candidiasis
Akpınar, A., Markiewicz, L. H., Harsa, H. Ş., Paveljšek, D., Domínguez-Soberanes, J., Ağırbaşlı, Z., Naziri, E., Jalil, M. H. E., Bouchaud, G., Seppo, S., et al. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1658988 · Cited by 3
Evaluating the Efficacy of Eradicating Gardnerella vaginalis Vaginal Colonization With Amoxicillin: A Randomized, Double-Blind, Phase 2 Study
McNeil, C. J., Tan, A., Powell, J. A., Pontius, A., Lewis, A., Myler, N., & Schwebke, J. R. (2021) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000001555 · Cited by 3
Obstetric factors associated with infections of the fetus and newborn infant
Riley, L. E., & Swamy, G. K. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-79525-8.00012-3 · Cited by 3
Bacterial vaginosis and associated bacteria
McLaughlin, S. E., Strenk, S. M., & Fredricks, D. N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-818619-0.00109-x · Cited by 3
A rare case of Gardnerella vaginalis spondylodiscitis
Belote, A., & Hammoud, K. A. (2024) · IDCases · doi:10.1016/j.idcr.2024.e02126 · Cited by 2
Influence of connatural factors in shaping vaginal microflora and ensuring its health
Das, S. K., & Konwar, B. K. (2023) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-023-07200-8 · Cited by 2
Vaginales Mikrobiom und Darmmikrobiom – ein Crosstalk
Mendling, W. (2024) · Geburtshilfe und Frauenheilkunde · doi:10.1055/a-2162-2903 · Cited by 1
Antagonistic and antibacterial activity of Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus La-14 included in the oral probiotic
Budilovskaya, O. V., Владимировна, С. Е., Shalepo, K. V., Khusnutdinova, T. А., Krysanova, A. А., Siniakova, A. A., Bespalova, O. N., & Savicheva, A. M. (2024) · Journal of obstetrics and women s diseases · doi:10.17816/jowd630698 · Cited by 2
Extravaginale Reservoire für die bakterielle Vaginose verantwortlich
Schwarz, T. F. (2012) · gynäkologie + geburtshilfe · doi:10.1007/s15013-012-0251-x · Cited by 1
The association between diversity and composition of vaginal microbiota of Iranian women with and without human papillomavirus infection
Behboodi, R., Hashemi, S., Javadi, S., Ghaniabadi, R., Mohammadzadeh, N., & Razavi, S. (2021) · Reviews in Medical Microbiology · doi:10.1097/mrm.0000000000000257 · Cited by 1
Bartholin’s gland cyst caused by Sneathia amnii: a case report
Zhang, R., Zhang, Z., Xu, M., Li, W., Sun, Y., Dai, Y., Yang, X., & Lin, S. (2023) · BMC Infectious Diseases · doi:10.1186/s12879-023-08302-z · Cited by 1
Diverse Metrics of Success for Physician-Scientists: Reflections on My Path and the Evolving Role of the National Institute of Allergy and Infectious Diseases
Marrazzo, J. M. (2024) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiae495 · Cited by 1

Authors: Marrazzo, J. M., Fiedler, T. L., Srinivasan, S., Thomas, K. K., Liu, C., Ko, D., Xie, H., Saracino, M., & Fredricks, D. N.
Affiliations: University of Washington (US)
Fred Hutch Cancer Center (US)
Corresponding author: Marrazzo, Jeanne M.
ORCID: Marrazzo, Jeanne M.
Fiedler, Tina L.
Srinivasan, Sujatha
Thomas, Katherine K.
Liu, Congzhou
Ko, Daisy
Xie, Hu
Fredricks, David N.
Venue: The Journal of Infectious Diseases
Publisher: Oxford University Press (OUP)
Published: 2012-03-23
Volume: 205
Issue: 10
Pages: 1580-1588
ISSN: 0022-1899 (ISSN-L)
1537-6613
DOI: 10.1093/infdis/jis242
PMC: PMC3415820
OpenAlex: W2139092047
Cited by: 123
References: 36
Citations by year: 2026: 6 · 2025: 7 · 2024: 10 · 2023: 8 · 2022: 5 · 2021: 14 · 2020: 12 · 2019: 10 · 2018: 6 · 2017: 9 · 2016: 8 · 2015: 3 · 2014: 9 · 2013: 9 · 2012: 6
FWCI: 7.47
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: The Journal of Infectious Diseases (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Cancer Institute (P30CA015704)
National Institute of Allergy and Infectious Diseases (R01AI052228, R01AI061628, R01 AI 52228-01)
Topics: Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
Keywords: bacterial vaginosis, Gardnerella vaginalis, Megasphaera, Lactobacillus crispatus, Lactobacillus jensenii, vaginal microbiota
MeSH terms: Adolescent, Adult, Anal Canal, Bacteria, Disease Reservoirs, DNA, Bacterial, Female, Follow-Up Studies, Gardnerella vaginalis, Humans, Lactobacillus, Mouth, Risk Factors, RNA, Ribosomal, 16S, Cohort Studies, Case-Control Studies, Vaginosis, Bacterial, Leptotrichia, Megasphaera, Metagenome, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Extravaginal reservoirs of vaginal bacteria as risk factors for incident bacterial vaginosis.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks