Cited by 248Machine Learning in HealthcareBiomedical Text Mining and OntologiesNursing Diagnosis and Documentation

Extracting social determinants of health from electronic health records using natural language processing: a systematic review

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Patra, Braja G, Sharma, Mohit M, Vekaria, Veer, Adekkanattu, Prakash, Patterson, Olga V, Glicksberg, Benjamin, Lepow, Lauren A, Ryu, Euijung +14 more·2021·Journal of the American Medical Informatics Association

Abstract

Objective: Social determinants of health (SDoH) are nonclinical dispositions that impact patient health risks and clinical outcomes. Leveraging SDoH in clinical decision-making can potentially improve diagnosis, treatment planning, and patient outcomes. Despite increased interest in capturing SDoH in electronic health records (EHRs), such information is typically locked in unstructured clinical notes. Natural language processing (NLP) is the key technology to extract SDoH information from clinical text and expand its utility in patient care and research. This article presents a systematic review of the state-of-the-art NLP approaches and tools that focus on identifying and extracting SDoH data from unstructured clinical text in EHRs. Materials and Methods: A broad literature search was conducted in February 2021 using 3 scholarly databases (ACL Anthology, PubMed, and Scopus) following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A total of 6402 publications were initially identified, and after applying the study inclusion criteria, 82 publications were selected for the final review. Results: Smoking status (n = 27), substance use (n = 21), homelessness (n = 20), and alcohol use (n = 15) are the most frequently studied SDoH categories. Homelessness (n = 7) and other less-studied SDoH (eg, education, financial problems, social isolation and support, family problems) are mostly identified using rule-based approaches. In contrast, machine learning approaches are popular for identifying smoking status (n = 13), substance use (n = 9), and alcohol use (n = 9). Conclusion: NLP offers significant potential to extract SDoH data from narrative clinical notes, which in turn can aid in the development of screening tools, risk prediction models, and clinical decision support systems.

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  1. [25]Velupillai S, Mowery DL, Conway M, Hurdle J, Kious B. Vocabulary development to support information extraction of substance abuse from psychiatry notes. In: Proceedings of the 15th Workshop on Biomedical Natural Language Processing. Association for Computational Linguistics; 2016: 92– 101.
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Authors
Patra, B. G., Sharma, M. M., Vekaria, V., Adekkanattu, P., Patterson, O. V., Glicksberg, B., Lepow, L. A., Ryu, E., Biernacka, J. M., Furmanchuk, A., George, T. J., Hogan, W., Wu, Y., Yang, X., Bian, J., Weissman, M., Wickramaratne, P., Mann, J. J., Olfson, M., Campion, T. R., Weiner, M., & Pathak, J.
Affiliations
  • Weill Cornell Medicine (US)
  • University of Utah (US)
  • Icahn School of Medicine at Mount Sinai (US)
  • Mayo Clinic (US)
  • Northwestern University (US)
  • University of Florida Health (US)
  • Columbia University (US)
Corresponding author
Pathak, Jyotishman
Venue
Journal of the American Medical Informatics Association
Published
2021-10-06
Volume
28
Issue
12
Pages
2716-2727
ISSN
  • 1067-5027 (ISSN-L)
  • 1527-974X
OpenAlex
W3202375701
Cited by
248
References
88
Citations by year
2026: 36 · 2025: 67 · 2024: 64 · 2023: 53 · 2022: 28
FWCI
2.62
Type
journal article
Language
en
Open access
Locations
  • Journal of the American Medical Informatics Association (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Funders
NIH (R01MH119177, R01MH121907, R01MH121922)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biomedical Text Mining and Ontologies
  • Health Sciences › Nursing › Issues, ethics and legal aspects › Nursing Diagnosis and Documentation
Keywords
social determinants of health, electronic health records, natural language processing, clinical text extraction, unstructured clinical notes, smoking status, substance use, homelessness, alcohol consumption, rule-based extraction, machine learning, clinical decision support, risk prediction model
MeSH terms
Machine Learning, Data Management, Humans, Natural Language Processing, Electronic Health Records, Social Determinants of Health

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