Entrez Gene: gene-centered information at NCBI
Open accessAbstract
Entrez Gene (www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene) is NCBI's database for gene-specific information. Entrez Gene includes records from genomes that have been completely sequenced, that have an active research community to contribute gene-specific information or that are scheduled for intense sequence analysis. The content of Entrez Gene represents the result of both curation and automated integration of data from NCBI's Reference Sequence project (RefSeq), from collaborating model organism databases and from other databases within NCBI. Records in Entrez Gene are assigned unique, stable and tracked integers as identifiers. The content (nomenclature, map location, gene products and their attributes, markers, phenotypes and links to citations, sequences, variation details, maps, expression, homologs, protein domains and external databases) is provided via interactive browsing through NCBI's Entrez system, via NCBI's Entrez programing utilities (E-Utilities), and for bulk transfer by ftp.
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EntrezGene numbers were used as a standard transcript accession system to ensure a correct over-representation analysis, as they allow mapping of gene identifiers to GO or KEGG biological categories.
“EntrezGene numbers [72] were used as a standard transcript accession system to ensure a correct over-representation analysis, as they allow one to map gene identifiers to GO or KEGG biological categories.”
From Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity (2008) · cites this paper as [72]
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Cites
Pruitt, K., Tatusova, T., & Maglott, D. (2004) · Nucleic Acids Res. · doi:10.1093/nar/gki025 · Cited by 3,248 · see citing works
Self-citationGeneration and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team* (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242603899 · Cited by 1,742 · see citing works
Database resources of the National Center for Biotechnology Information
Wheeler, D. L., Barrett, T., Benson, D. A., Bryant, S. H., Canese, K., Chetvernin, V., Church, D. M., DiCuccio, M., Edgar, R., Federhen, S., et al. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm1000 · Cited by 1,007 · see citing works
Self-citationDatabase resources of the National Center for Biotechnology Information
Wheeler, D. L., Barrett, T., Benson, D. A., Bryant, S. H., Canese, K., Chetvernin, V., Church, D. M., DiCuccio, M., Edgar, R., Federhen, S., et al. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkl1031 · Cited by 734 · see citing works
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Research works printed but not linked: 1
- [3]Benson D.A. Karsch-Mizrachi I. Lipman D.J. Ostell J. Wheeler D.L. GenBank Nucleic Acid Res. 2007 (Submitted) PMC102453 10592170
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Huang, D. W., Sherman, B. T., & Lempicki, R. A. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkn923 · Cited by 14,108 · see citing works
MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins
Calvo, S. E., Clauser, K. R., & Mootha, V. K. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkv1003 · Cited by 1,251 · see citing works
The Human Gene Mutation Database: 2008 update
Stenson, P. D., Mort, M., Ball, E. V., Howells, K., Phillips, A. D., Thomas, N. S., & Cooper, D. N. (2009) · Genome Medicine · doi:10.1186/gm13 · Cited by 873 · see citing works
PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update
Wang, X., Spandidos, A., Wang, H., & Seed, B. (2012) · Nucleic Acids Research · doi:10.1093/nar/gkr1013 · Cited by 720 · see citing works
NCBI Reference Sequences: current status, policy and new initiatives
Pruitt, K. D., Tatusova, T., Klimke, W., & Maglott, D. R. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkn721 · Cited by 736 · see citing works
“RefSeqs are an integral part of many resources at NCBI, including the Gene database (5), the Map Viewer and HomoloGene.”
Self-citationDatabase resources of the National Center for Biotechnology Information
Wheeler, D. L., Barrett, T., Benson, D. A., Bryant, S. H., Canese, K., Chetvernin, V., Church, D. M., DiCuccio, M., Edgar, R., Federhen, S., et al. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkl1031 · Cited by 734 · see citing works
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Henegar, C., Tordjman, J., Achard, V., Lacasa, D., Cremer, I., Guerre-Millo, M., Poitou, C., Basdevant, A., Stich, V., Viguerie, N., et al. (2008) · Genome Biology · doi:10.1186/gb-2008-9-1-r14 · Cited by 471 · see citing works
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PepBank - a database of peptides based on sequence text mining and public peptide data sources.
Shtatland, T., Guettler, D., Kossodo, M., Pivovarov, M., & Weissleder, R. (2007) · BMC Bioinformatics · doi:10.1186/1471-2105-8-280 · Cited by 181 · see citing works
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AlphaFold illuminates half of the dark human proteins
Binder, J. L., Berendzen, J., Stevens, A. O., He, Y., Wang, J., Dokholyan, N. V., & Oprea, T. I. (2022) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2022.102372 · Cited by 81 · see citing works
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Chitwood, D. G., Wang, Q., Klaubert, S. R., Green, K., Wu, C. H., Harcum, S. W., & Saski, C. A. (2023) · Scientific Reports · doi:10.1038/s41598-023-27962-0 · Cited by 12 · see citing works
- Authors
- Maglott, D., Ostell, J., Pruitt, K. D., & Tatusova, T.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Maglott, D.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-01-03
- Volume
- 35
- Issue
- Database
- Pages
- D26-D31
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- PMC
- PMC1761442
- OpenAlex
- W4320800138
- Cited by
- 633
- References
- 4
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 27 · 2023: 23 · 2022: 13 · 2021: 17 · 2020: 11 · 2019: 12 · 2018: 8 · 2017: 14 · 2016: 15 · 2015: 16 · 2014: 24 · 2013: 34 · 2012: 43
- FWCI
- 29.20
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- Nucleic Acids Research (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biomedical Text Mining and Ontologies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bioinformatics and Genomic Networks
- Keywords
- Entrez Gene, NCBI, reference sequences, model organism databases, gene nomenclature, gene mapping, gene products, genetic markers, phenotypes, sequence variation, homologous genes, protein domains, genome annotation
- MeSH terms
- Genes, National Library of Medicine (U.S.), United States, User-Computer Interface, Internet, Genomics, Databases, Genetic
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