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Cited by 2,020

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

20 years of the SMART protein domain annotation resource

Open access
Letunic, Ivica, Bork, Peer·2018·Nucleic Acids Research
DOI 10.1093/nar/gkx922
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Abstract

SMART (Simple Modular Architecture Research Tool) is a web resource (http://smart.embl.de) for the identification and annotation of protein domains and the analysis of protein domain architectures. SMART version 8 contains manually curated models for more than 1300 protein domains, with approximately 100 new models added since our last update article (1). The underlying protein databases were synchronized with UniProt (2), Ensembl (3) and STRING (4), doubling the total number of annotated domains and other protein features to more than 200 million. In its 20th year, the SMART analysis results pages have been streamlined again and its information sources have been updated. SMART's vector based display engine has been extended to all protein schematics in SMART and rewritten to use the latest web technologies. The internal full text search engine has been redesigned and updated, resulting in greatly increased search speed.

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Research works printed but not linked: 18

  1. 2015, SMART: recent updates, new developments and status in 2015, Nucleic Acids Res., 43, D257, 10.1093/nar/gku949 · DOI · Paper page
  2. The UniProt, C., 2017, UniProt: the universal protein knowledgebase, Nucleic Acids Res., 45, D158, 10.1093/nar/gkw1099 · DOI · Paper page
  3. 1991, PROSITE: a dictionary of sites and patterns in proteins, Nucleic Acids Res., 19, 2241, 10.1093/nar/19.suppl.2241 · DOI · Paper page
  4. 1987, Profile analysis: detection of distantly related proteins, Proc. Natl. Acad. Sci. U.S.A., 84, 4355, 10.1073/pnas.84.13.4355 · DOI · Paper page
  5. 1989, A method for property pattern searches in protein sequence databases, demonstrated by detection of GTP binding sites, Stud. Biophys., 129, 231
  6. 1989, Recognition of functional regions in primary structures using a set of property patterns, FEBS Lett., 257, 191, 10.1016/0014-5793(89)81818-6 · DOI
  7. 1991, Shuffled domains in extracellular proteins, FEBS Lett., 286, 47, 10.1016/0014-5793(91)80937-X · DOI
  8. 1992, Comprehensive sequence analysis of the 182 predicted open reading frames of yeast chromosome III, Protein Sci., 1, 1677, 10.1002/pro.5560011216 · DOI
  9. 1994, Hidden Markov models in computational biology. Applications to protein modeling, J. Mol. Biol., 235, 1501, 10.1006/jmbi.1994.1104 · DOI
  10. 1998, SMART, a simple modular architecture research tool: identification of signaling domains, Proc. Natl. Acad. Sci. U.S.A., 95, 5857, 10.1073/pnas.95.11.5857 · DOI
  11. 2016, The Pfam protein families database: towards a more sustainable future, Nucleic Acids Res., 44, D279, 10.1093/nar/gkv1344 · DOI · Paper page
  12. 2017, PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements, Nucleic Acids Res., 45, D183, 10.1093/nar/gkw1138 · DOI · Paper page
  13. 2013, New and continuing developments at PROSITE, Nucleic Acids Res., 41, D344
  14. 2017, InterPro in 2017-beyond protein family and domain annotations, Nucleic Acids Res., 45, D190, 10.1093/nar/gkw1107 · DOI · Paper page
  15. 2009, SMART 6: recent updates and new developments, Nucleic Acids Res., 37, D229, 10.1093/nar/gkn808 · DOI · Paper page
  16. 2016, eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences, Nucleic Acids Res., 44, D286, 10.1093/nar/gkv1248 · DOI · Paper page
  17. 2015, PTMcode v2: a resource for functional associations of post-translational modifications within and between proteins, Nucleic Acids Res., 43, D494, 10.1093/nar/gku1081 · DOI
  18. 2016, Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees, Nucleic Acids Res., 44, W242, 10.1093/nar/gkw290 · DOI

Cited by

Metadata

Authors
Letunic, I., & Bork, P.
Venue
Nucleic Acids Research
Publisher
Oxford University Press (OUP)
Published
2017-10-10
Volume
46
Issue
D1
Pages
D493-D496
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
DOI
10.1093/nar/gkx922
OpenAlex
W2761688050
Cited by
2,020
References
3
FWCI
67.46
Type
journal article
Language
en
Open access
gold
Licence
creativecommons.org/licenses/by-nc/4.0/ (vor)

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