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OrthoDB v10: sampling the diversity of animal, plant, fungal, protist, bacterial and viral genomes for evolutionary and functional annotations of orthologs
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Most orthology inference methods rely on sequence alignments and often incorporate a specific alignment overlap criterion as part of the orthology algorithm.
“Most orthology inference methods rely on sequence alignments and often incorporate a specific alignment overlap criteria as part of the orthology algorithm [e.g. OMA (Train et al. 2017), OrthoDB (Kriventseva et al. 2019), PANTHER (Thomas et al. 2022)].”
From Annotation matters: the effect of structural gene annotation on orthology inference (2025) · cites this paper as Kriventseva et al. 2019
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Federhen, S. (2012) · Nucleic Acids Research · doi:10.1093/nar/gkr1178 · Cited by 1,436
The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution
The Bovine Genome Sequencing and Analysis Consortium, Elsik, C. G., Tellam, R. L., Worley, K. C., Gibbs, R. A., Muzny, D. M., Weinstock, G. M., Adelson, D. L., Eichler, E. E., Elnitski, L., et al. (2009) · Science · doi:10.1126/science.1169588 · Cited by 1,287
Self-citationFunctional and evolutionary implications of gene orthology
Gabaldón, T., & Koonin, E. V. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3456 · Cited by 643
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Research works printed but not linked: 24
- Fitch, 2000, Homology a personal view on some of the problems, Trends Genet., 16, 227, 10.1016/S0168-9525(00)02005-9 · DOI
- Koonin, 2005, Orthologs, paralogs, and evolutionary genomics, Annu. Rev. Genet., 39, 309, 10.1146/annurev.genet.39.073003.114725 · DOI · Paper page
- Tatusov, 1997, A genomic perspective on protein families, Science, 278, 631, 10.1126/science.278.5338.631 · DOI
- van der Heijden, 2007, Orthology prediction at scalable resolution by phylogenetic tree analysis, BMC Bioinformatics, 8, 83, 10.1186/1471-2105-8-83 · DOI
- Fischer, 2011, Using OrthoMCL to assign proteins to OrthoMCL-DB groups or to cluster proteomes into new ortholog groups, Curr. Protoc. Bioinform., 10.1002/0471250953.bi0612s35 · DOI
- Nakaya, 2013, KEGG OC: a large-scale automatic construction of taxonomy-based ortholog clusters, Nucleic Acids Res., 41, D353, 10.1093/nar/gks1239 · DOI
- Huerta-Cepas, 2014, PhylomeDB v4: zooming into the plurality of evolutionary histories of a genome, Nucleic Acids Res., 42, D897, 10.1093/nar/gkt1177 · DOI · Paper page
- Sonnhammer, 2015, InParanoid 8: orthology analysis between 273 proteomes, mostly eukaryotic, Nucleic Acids Res., 43, D234, 10.1093/nar/gku1203 · DOI
- Uchiyama, 2015, MBGD update 2015: microbial genome database for flexible ortholog analysis utilizing a diverse set of genomic data, Nucleic Acids Res., 43, D270, 10.1093/nar/gku1152 · DOI
- Huerta-Cepas, 2016, eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences, Nucleic Acids Res., 44, D286, 10.1093/nar/gkv1248 · DOI
- Galperin, 2017, Microbial genome analysis: the COG approach, Brief. Bioinform.
- Zdobnov, 2017, OrthoDB v9.1: cataloging evolutionary and functional annotations for animal, fungal, plant, archaeal, bacterial and viral orthologs, Nucleic Acids Res., 45, D744, 10.1093/nar/gkw1119 · DOI · Paper page
- Altenhoff, 2018, The OMA orthology database in 2018: retrieving evolutionary relationships among all domains of life through richer web and programmatic interfaces, Nucleic Acids Res., 46, D477, 10.1093/nar/gkx1019 · DOI · Paper page
- Kriventseva, 2015, OrthoDB v8: update of the hierarchical catalog of orthologs and the underlying free software, Nucleic Acids Res., 43, D250, 10.1093/nar/gku1220 · DOI
- Trachana, 2011, Orthology prediction methods: a quality assessment using curated protein families, Bioessays, 33, 769, 10.1002/bies.201100062 · DOI · Paper page
- Waterhouse, 2007, Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes, Science, 316, 1738, 10.1126/science.1139862 · DOI
- Hoy, 2016, Genome sequencing of the phytoseiid predatory mite metaseiulus occidentalis reveals completely atomized hox genes and superdynamic intron evolution, Genome Biol. Evol., 8, 1762, 10.1093/gbe/evw048 · DOI
- i, K.C., 2013, The i5K Initiative: advancing arthropod genomics for knowledge, human health, agriculture, and the environment, J. Hered., 104, 595, 10.1093/jhered/est050 · DOI
- Kriventseva, 2008, OrthoDB: the hierarchical catalog of eukaryotic orthologs, Nucleic Acids Res., 36, D271, 10.1093/nar/gkm845 · DOI
- Waterhouse, 2011, Correlating traits of gene retention, sequence divergence, duplicability and essentiality in vertebrates, arthropods, and fungi, Genome Biol. Evol., 3, 75, 10.1093/gbe/evq083 · DOI
- Waterhouse, 2017, BUSCO applications from quality assessments to gene prediction and phylogenomics, Mol. Biol. Evol., 35, 543, 10.1093/molbev/msx319 · DOI · Paper page
- Ondov, 2016, Mash: fast genome and metagenome distance estimation using MinHash, Genome Biol., 17, 132, 10.1186/s13059-016-0997-x · DOI · Paper page
- Simao, 2015, BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs, Bioinformatics, 31, 3210, 10.1093/bioinformatics/btv351 · DOI · Paper page
- Steinegger, 2017, MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets, Nat. Biotechnol., 35, 1026, 10.1038/nbt.3988 · DOI · Paper page
Cited by
Sorted by citations
Manni, M., Berkeley, M. R., Seppey, M., Simão, F. A., & Zdobnov, E. M. (2021) · Molecular Biology and Evolution · doi:10.1093/molbev/msab199 · Cited by 6,187
Self-citationGenomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts
Opulente, D. A., LaBella, A. L., Harrison, M.-C., Wolters, J. F., Liu, C., Li, Y., Kominek, J., Steenwyk, J. L., Stoneman, H. R., VanDenAvond, J., et al. (2024) · Science · doi:10.1126/science.adj4503 · Cited by 121
Alexander, H., Hu, S. K., Krinos, A. I., Pachiadaki, M., Tully, B. J., Neely, C. J., & Reiter, T. (2021) · doi:10.1101/2021.07.25.453713 · Cited by 67
Computed cancer interactome explains the effects of somatic mutations in cancers
Zhang, J., Pei, J., Durham, J., Bos, T., & Cong, Q. (2022) · Protein Science · doi:10.1002/pro.4479 · Cited by 31
Annotation matters: the effect of structural gene annotation on orthology inference
Prieto-Baños, S., Nevers, Y., Altenhoff, A., Warwick Vesztrocy, A., Dessimoz, C., & Glover, N. M. (2025) · Bioinformatics · doi:10.1093/bioinformatics/btaf365 · Cited by 19
Ancient roots: A Cambrian explosion of autism susceptibility genes
Casanova, E. L. (2023) · Autism Research · doi:10.1002/aur.2984 · Cited by 5
Metadata
- Authors
- Kriventseva, E. V., Kuznetsov, D., Tegenfeldt, F., Manni, M., Dias, R., Simão, F. A., & Zdobnov, E. M.
- Affiliations
- Department of Genetic Medicine and Development, University of Geneva Medical School, rue Michel-Servet 1, 1211 Geneva, Switzerland
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2018-11-05
- Volume
- 47
- Issue
- D1
- Pages
- D807-D811
- ISSN
- 0305-1048
- 1362-4962
- PMC
- PMC6323947
- Cited by
- 1,232
- References
- 3
- Language
- en
- Funders
- Swiss National Science Foundation (31003A_166483)
- São Paulo Research Foundation (17/15195–2)
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