Cited by 158Smoking Behavior and CessationAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesSubstance Abuse Treatment and Outcomes

The DOI matches its Crossref record; 67 of the 67 references it cites were found in a registry or an index; none of the 33 sources its claims cite is checked for support yet.

Anxiety sensitivity and anxiety and depressive symptoms in the prediction of early smoking lapse and relapse during smoking cessation treatment

Open access

Abstract

INTRODUCTION: The present investigation examined whether anxiety sensitivity, relative to anxiety and depressive symptoms, was related to duration to early smoking lapse and relapse (during first 2 weeks postquit) among daily smokers receiving smoking cessation treatment. METHODS: Participants included 123 daily cigarette smokers (84 women; M(age) = 45.93 years, SD = 10.34) living in the Halifax Regional Municipality in Nova Scotia, Canada. RESULTS: Anxiety sensitivity was significantly associated with an increased risk of early smoking lapse (i.e., any smoking behavior) at days 1, 7, and 14 following the quit day. Such effects were evident above and beyond the variance accounted for by gender, nicotine dependence, and nicotine withdrawal symptoms, as well as the shared variance with prequit (baseline) anxiety and depressive symptoms. In contrast to expectation, anxiety sensitivity was not related to smoking relapse (i.e., seven consecutive days of smoking) during the first 2 weeks of quitting. DISCUSSION: Results are discussed in terms of better understanding the role of anxiety sensitivity, along with other affective vulnerability processes, in early problems encountered during a quit attempt.

Overview

AI snapshot

Written from the paper’s full text.

TL;DR

Among daily smokers in a 4-week group cessation program, higher anxiety sensitivity predicted earlier smoking lapse during the first 2 weeks post-quit but did not predict relapse. Depressive symptoms, not anxiety symptoms, predicted early relapse.

Key findings

  • Anxiety sensitivity (ASI-Total) was significantly associated with lapse at day 1 (OR = 1.04, p < .05), day 7 (HR = 1.02, p < .05), and day 14 (HR = 1.02, p < .05), above gender, nicotine dependence, nicotine withdrawal, and baseline anxiety/depressive symptoms.
  • Anxiety sensitivity was not significantly related to relapse; instead, depressive symptoms (MASQ-AD) predicted relapse at day 1 (OR = 1.07, p < .01), day 7 (HR = 1.05, p < .01), and day 14 (HR = 1.03, p = .01).
  • Depressive symptoms also predicted day 1 lapse (OR = 1.04, p < .05), while anxious arousal (MASQ-AA) was not significantly associated with lapse or relapse.
  • By day 14 postcessation, 74.5% (n = 79) lapsed and 45.7% (n = 48) relapsed; at day 1, 52.9% lapsed and 24.5% relapsed; at day 7, 68.3% lapsed and 28.2% relapsed.

Methods

  • Prospective study of 123 daily cigarette smokers (84 women; M age = 45.93 years) recruited from a structured 4-week group Tobacco Intervention Program in Halifax, Nova Scotia; analyses included 106 participants with smoking calendar data at or following the quit day.
  • Baseline measures included the Smoking History Questionnaire, Fagerström Test for Nicotine Dependence, Minnesota Nicotine Withdrawal Scale (quit day), Mood and Anxiety Symptom Questionnaire (Anxious Arousal and Anhedonic Depression subscales), and Anxiety Sensitivity Index.
  • Participants completed daily smoking calendar logs for 2 weeks before and 2 weeks after the quit date; analyses used zero-order correlations, logistic regression for day 1 lapse/relapse, and Cox proportional hazards regression for day 7 and day 14 outcomes, with gender, FTND, and MWS as covariates.

Limitations

  • The paper states the sample was relatively homogeneous (e.g., primarily White) and self-selected, limiting generalizability; it also notes the study included only some possible emotional risk factors, relied on self-reported smoking logs without biochemical verification, lacked diagnostic assessments, and did not fix the quit date relative to the 4-week program.
  • The treatment context may limit conclusions about anxiety sensitivity and relapse: the authors note that evidence-based cessation care may have helped anxiety-sensitive smokers recover from lapses, and suggest future self-guided quit attempts or longer follow-up may be needed.
  • The 2-week post-quit timeframe may have been too short to detect anxiety sensitivity–relapse effects, as the authors state.

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Integrity signals

Registry

Crossref · 10.1093/ntr/ntn037

Cites

67 of 67 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

0 of 33 cited sources checked · 0 supported · 0 flagged

Show all 29 claims

  • It may state two separate claims as one. 11
  • Probably not a substantial claim. 18
25 of 25
  • The paper relies on this without support.

    NRT use did not confound the relationships between the predictors (anxiety sensitivity, anxiety, depressive symptoms, nicotine dependence) and early lapse/relapse.

    “Participants had the option of using nicotine replacement therapy (NRT) during the study (see Measures and Procedure), and all accepted the optional NRT.”
  • The paper relies on this without support.

    The association between anxiety sensitivity and early lapse/relapse is not due to unmeasured confounding.

    “Each model included gender, nicotine dependence (FTND-Total), and nicotine withdrawal -quit day (MWS-Total) as theoretically relevant covariates.”
  • The paper relies on this without support.

    The timing of quit dates relative to the 4-week program averaged out across participants.

    “Although this timing should have averaged out across participants, it would be ideal to standardize the quit date relative to the program start in future research.”
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Citations

Cites

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Research works printed but not linked: 1

  1. Taylor, 1999, Anxiety sensitivity: Theory, research, and treatment of the fear of anxiety

Cited by

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Items 101–158 of 158

Metadata

Authors
Zvolensky, M. J., Stewart, S. H., Vujanovic, A. A., Gavric, D., & Steeves, D.
Affiliations
University of Vermont (US)
Corresponding author
Zvolensky, Michael J.
Venue
Nicotine & Tobacco Research
Published
2009-02-23
Volume
11
Issue
3
Pages
323-331
ISSN
  • 1462-2203 (ISSN-L)
  • 1469-994X
OpenAlex
W2171742037
Cited by
158
References
63
Citations by year
2026: 1 · 2025: 3 · 2024: 2 · 2023: 11 · 2022: 8 · 2021: 7 · 2020: 9 · 2019: 9 · 2018: 10 · 2017: 5 · 2016: 15 · 2015: 14 · 2014: 21 · 2013: 15 · 2012: 14
FWCI
5.74
Type
journal article
Language
en
Open access
Locations
  • Nicotine & Tobacco Research (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • HighWire Press Open Archive (submittedVersion)
Funders
  • Dalhousie University
  • Killam Trusts
  • National Institutes of Health (5r01da018734-03)
  • Canadian Institutes of Health Research
  • National Institute of Mental Health (MH 076629-01, R01MH076629)
  • National Institute on Drug Abuse (R03DA016307, DA 16307-01, F31DA021006, DA018734--01A1, DA021006-01)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
anxiety sensitivity, smoking cessation, smoking relapse, anxiety symptoms, depressive symptoms, nicotine dependence, nicotine withdrawal symptoms, emotional vulnerability, daily smokers
MeSH terms
Smoking Prevention, Adult, Anxiety, Depression, Female, Forecasting, Humans, Male, Middle Aged, Nova Scotia, Surveys and Questionnaires, Recurrence, Smoking, Substance Withdrawal Syndrome, Smoking Cessation

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