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Cited by 26Coffee research and impactsAlcohol Consumption and Health EffectsNutritional Studies and Diet

Coffee consumption and myocardial infarction in women

VECCHIA, CARLO LA, GENTILE, ANTONELLA, NEGRI, EVA, PARAZZINI, FABIO, FRANCESCH, SILVIA·1989·American Journal of Epidemiology
DOI 10.1093/oxfordjournals.aje.a115361
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Abstract

The relation between coffee consumption and the risk of acute myocardial infarction was evaluated in a hospital-based case-control study conducted in northern Italy between 1983 and 1987. The study consisted of 262 women with acute myocardial infarction and 519 controls admitted to the hospital for acute, nondigestive tract disorders. Information was obtained on the average number of cups of coffee or decaffeinated coffee consumed per day before the onset of the disease which led to hospital admission and on the total duration in years of the habit. There was a positive association between heavy coffee drinking and risk of myocardial infarction (relative risk (RR) = 2.7 for consumption of four cups or more per day). After allowance for smoking and other relevant covariates, the relative risk was not elevated for consumption of up to three cups per day, but still above unity for consumption of four or more cups per day (RR = 1.7), and the multivariate trend in risk was still significant (X1(2) = 5.14, p = 0.02). The risk estimates were grossly elevated among hyperlipidemic women (multivariate RR = 7.6 for moderate and 17.9 for heavy coffee drinkers). As a result of small absolute numbers, these estimates were largely unstable and the interaction between coffee and hyperlipidemia was not statistically significant. Such estimates, nonetheless, are of potential interest in terms of etiologic correlates and implications for prevention.

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Crossref · 10.1093/oxfordjournals.aje.a115361

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  • In the study by LaVecchia et al, the age adjusted odds ratio for drinking four or more cups/day was 2.65 (95% CI 1.56 to 4.52) compared with 1.72 (95% CI 0.92 to 3.23) after adjustment for smoking and a range of other CHD risk factors.

    “For example, in the study by LaVecchia et al,32 the age adjusted odds ratio for drinking four or more cups/day was 2.65 (95% CI 1-56 to 4 52) compared with 1-72 (95% CI 092 to 3 23) after adjustment for smoking and a range of other CHD risk factors.”

    From Does coffee drinking increase the risk of coronary heart disease? Results from a meta‐analysis (1994) · cites this paper as [32]

  • The problem of recall bias is compounded by ascertainment of coffee intake by interviewers who were not blinded with respect to the case-control state of patients.

    “This problem is compounded by ascertainment of coffee intake by interviewers who were not blinded with respect to the case-control state of patients.30323'”

    From Does coffee drinking increase the risk of coronary heart disease? Results from a meta‐analysis (1994) · cites this paper as [32]

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Authors
VECCHIA, C. L., GENTILE, A., NEGRI, E., PARAZZINI, F., & FRANCESCH, S.
Affiliations
  • Mario Negri Institute for Pharmacological Research (IT)
  • Centro di Riferimento Oncologico (IT)
Corresponding author
VECCHIA, CARLO LA
ORCID
Venue
American Journal of Epidemiology
Publisher
Oxford University Press (OUP)
Published
1989-09
Volume
130
Issue
3
Pages
481-485
ISSN
  • 0002-9262 (ISSN-L)
  • 1476-6256
DOI
10.1093/oxfordjournals.aje.a115361
OpenAlex
W1891883641
Cited by
26
References
0
Citations by year
2020: 2 · 2016: 1
FWCI
3.23
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Epidemiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology › Coffee research and impacts
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords
coffee consumption, myocardial infarction, women, decaffeinated coffee, hyperlipidemia, smoking, cardiovascular risk factors, prevention
MeSH terms
Adult, Aged, Alcohol Drinking, Coffee, Female, Humans, Hypertension, Lipids, Middle Aged, Myocardial Infarction, Risk Factors, Smoking, Diabetes Complications

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