SERUM PLANT STEROLS AND CHOLESTEROL PRECURSORS REFLECT CHOLESTEROL ABSORPTION AND SYNTHESIS IN VOLUNTEERS OF A RANDOMLY SELECTED MALE POPULATION

Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9

Cohen, J., Pertsemlidis, A., Kotowski, I. K., Graham, R., Garcia, C. K., & Hobbs, H. H. (2005) · Nature Genetics · doi:10.1038/ng1509 · Cited by 1,381 · see citing works

Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo

Fassbender, K. C., Simons, M., Bergmann, C., Stroick, M., Lütjohann, D., Keller, P., Runz, H., Kühl, S., Bertsch, T., von Bergmann, K., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.081620098 · Cited by 1,088 · see citing works

Efficacy and Safety of Plant Stanols and Sterols in the Management of Blood Cholesterol Levels

Katan, M., Grundy, S. M., Jones, P. J. H., Law, M., Miettinen, T. A., & Paoletti, R. (2003) · Mayo Clinic Proceedings · doi:10.4065/78.8.965 · Cited by 1,078 · see citing works

Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population

Miettinen, T. A., Puska, P., Gylling, H., Vanhanen, H., & Vartiainen, E. (1995) · New England Journal of Medicine · doi:10.1056/nejm199511163332002 · Cited by 739 · see citing works

P HYTOSTEROLS IN H UMAN N UTRITION

Ostlund, R. E. (2002) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.22.020702.075220 · Cited by 645 · see citing works

Dietary phytosterols: A review of metabolism, benefits and side effects

Ling, W. H., & Jones, P. J. H. (1995) · Life Sciences · doi:10.1016/0024-3205(95)00263-6 · Cited by 562 · see citing works

Amaranth oil application for coronary heart disease and hypertension.

Martirosyan, D. M., La, M., Sn, K., Pogojeva, A. V., & Zoloedov, V. I. (2007) · Lipids in Health and Disease · doi:10.1186/1476-511x-6-1 · Cited by 390 · see citing works

Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels

Cohen, J. C., Pertsemlidis, A., Fahmi, S., Esmail, S., Vega, G. L., Grundy, S. M., & Hobbs, H. H. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508483103 · Cited by 380 · see citing works

Plant sterols: factors affecting their efficacy and safety as functional food ingredients.

Berger, A., Jones, P. J. H., & AbuMweis, S. S. (2004) · Lipids in Health and Disease · doi:10.1186/1476-511x-3-5 · Cited by 350 · see citing works

Dietary phytosterols as cholesterol-lowering agents in humans

Jones, P. J. H., MacDougall, D. E., Ntanios, F. Y., & Vanstone, C. A. (1997) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-75-3-217 · Cited by 337 · see citing works

Phytosterols: From Preclinical Evidence to Potential Clinical Applications

Salehi, B., Quispe, C., Sharifi‐Rad, J., Martins, N. A., Nigam, M., Mishra, A. P., Коновалов, Д. А., Orobinskaya, V. N., Abu‐Reidah, I. M., Zam, W., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.599959 · Cited by 333 · see citing works

Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2022

Okamura, T., Tsukamoto, K., Arai, H., Fujioka, Y., Ishigaki, Y., Koba, S., Ohmura, H., Shoji, T., Yokote, K., Yoshida, H., et al. (2023) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.gl2022 · Cited by 320 · see citing works

Intestinal absorption of triglyceride and cholesterol. Dietary and pharmacological inhibition to reduce cardiovascular risk

Ros, E. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(00)00456-1 · Cited by 319 · see citing works

Regulation of Intestinal Cholesterol Absorption

Wang, D. Q. ‐. (2006) · Annual Review of Physiology · doi:10.1146/annurev.physiol.69.031905.160725 · Cited by 311 · see citing works

High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial

PAIVA, H., THELEN, K., COSTER, R., SMET, J., PAEPE, B., MATTILA, K., LAAKSO, J., LEHTIMAKI, T., VONBERGMANN, K., & LUTJOHANN, D. (2005) · Clinical Pharmacology & Therapeutics · doi:10.1016/j.clpt.2005.03.006 · Cited by 308 · see citing works

Plant Stanol and Sterol Esters in the Control of Blood Cholesterol Levels: Mechanism and Safety Aspects

Plat, J., & Mensink, R. P. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.03.015 · Cited by 307 · see citing works

Phytosterols and cardiovascular health

Marangoni, F., & Poli, A. (2010) · Pharmacological Research · doi:10.1016/j.phrs.2010.01.001 · Cited by 301 · see citing works

Ezetimibe Effectively Reduces Plasma Plant Sterols in Patients With Sitosterolemia

Salen, G., von Bergmann, K., Lütjohann, D., Kwiterovich, P. O., Kane, J. P., Patel, S. B., Musliner, T., Stein, P., & Musser, B. (2004) · Circulation · doi:10.1161/01.cir.0000116766.31036.03 · Cited by 300 · see citing works

Phytosterols as a natural anticancer agent: Current status and future perspective

Shahzad, N., Khan, W., Md, S., Ali, A., Saluja, S. S., Sharma, S., Al-Allaf, F. A., Abduljaleel, Z., Ibrahim, I. A. A., Abdel-Wahab, A. F., et al. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.01.068 · Cited by 295 · see citing works

Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial

Jones, M. L., Martoni, C. J., & Prakash, S. (2012) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2012.126 · Cited by 277 · see citing works

Baseline serum cholestanol as predictor of recurrent coronary events in subgroup of Scandinavian simvastatin survival study

Miettinen, T. A., Gylling, H., Strandberg, T. E., & Sarna, S. J. (1998) · BMJ · doi:10.1136/bmj.316.7138.1127 · Cited by 255 · see citing works

Effects of 2 low-fat stanol ester–containing margarines on serum cholesterol concentrations as part of a low-fat diet in hypercholesterolemic subjects

Hallikainen, M., & Uusitupa, M. I. J. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.3.403 · Cited by 242 · see citing works

Cholesterol-lowering efficacy of a sitostanol-containing phytosterol mixture with a prudent diet in hyperlipidemic men

Jones, P. J. H., Ntanios, F. Y., Raeini−Sarjaz, M., & Vanstone, C. A. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.6.1144 · Cited by 242 · see citing works

Sterol absorption and sterol balance in phytosterolemia evaluated by deuterium-labeled sterols: effect of sitostanol treatment.

Lütjohann, D., Björkhem, I., Beil, U., & von Bergmann, K. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41495-6 · Cited by 238 · see citing works

Plant Stanol Esters Affect Serum Cholesterol Concentrations of Hypercholesterolemic Men and Women in a Dose-dependent Manner

Hallikainen, M., Sarkkinen, E. S., & Uusitupa, M. I. J. (2000) · Journal of Nutrition · doi:10.1093/jn/130.4.767 · Cited by 235 · see citing works

Oat beta-glucan increases bile acid excretion and a fiber-rich barley fraction increases cholesterol excretion in ileostomy subjects

Amundsen, Å. L., Hallmans, G., Sandberg, A.-S., Sundberg, B., Åman, P., & Andersson, H. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.6.1245 · Cited by 229 · see citing works

Reduction of Serum Cholesterol in Postmenopausal Women With Previous Myocardial Infarction and Cholesterol Malabsorption Induced by Dietary Sitostanol Ester Margarine

Gylling, H., Radhakrishnan, R., & Miettinen, T. A. (1997) · Circulation · doi:10.1161/01.cir.96.12.4226 · Cited by 228 · see citing works

Stimulation of Fecal Steroid Excretion After Infusion of Recombinant Proapolipoprotein A-I

Eriksson, M., Carlson, L. A., Miettinen, T. A., & Angelin, B. (1999) · Circulation · doi:10.1161/01.cir.100.6.594 · Cited by 227 · see citing works

Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8

Berge, K. E., von Bergmann, K., Lütjohann, D., Guerra, R., Grundy, S. M., Hobbs, H. H., & Cohen, J. C. (2002) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)30155-3 · Cited by 223 · see citing works

Serum cholesterol, cholesterol precursors, and plant sterols in hypercholesterolemic subjects with different apoE phenotypes during dietary sitostanol ester treatment

Vanhanen, H., Blomqvist, S. R., Ehnholm, C., Hyvönen, M., Jauhiainen, M., Torstila, I., & Miettinen, T. A. (1993) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)36946-7 · Cited by 211 · see citing works

Plant sterols and cardiovascular disease: a systematic review and meta-analysis†

Genser, B., Silbernagel, G., De Backer, G., Bruckert, E., Carmena, R., Chapman, M. J., Deanfield, J., Descamps, O. S., Rietzschel, E. R., Dias, K. C., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehr441 · Cited by 209 · see citing works

Noncholesterol Sterols and Cholesterol Lowering by Long-Term Simvastatin Treatment in Coronary Patients

Miettinen, T. A., Strandberg, T. E., & Gylling, H. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.5.1340 · Cited by 209 · see citing works

Relationships of serum plant sterols (phytosterols) and cholesterol in 595 hypercholesterolemic subjects, and familial aggregation of phytosterols, cholesterol, and premature coronary heart disease in hyperphytosterolemic probands and their first-degree relatives

Glueck, C. J., Speirs, J., Tracy, T., Streicher, P., Illig, E., & Vandegrift, J. (1991) · Metabolism · doi:10.1016/0026-0495(91)90013-m · Cited by 205 · see citing works

Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men

Pihlajamäki, J., Gylling, H. K., Miettinen, T. A., & Laakso, M. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m300368-jlr200 · Cited by 202 · see citing works

Serum cholesterol and cholesterol and lipoprotein metabolism in hypercholesterolaemic NIDDM patients before and during sitostanol ester-margarine treatment

Gylling, H., & Miettinen, T. A. (1994) · Diabetologia · doi:10.1007/bf00404334 · Cited by 202 · see citing works

Sitostanol ester margarine in dietary treatment of children with familial hypercholesterolemia.

Gylling, H., Siimes, M. A., & Miettinen, T. A. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41499-3 · Cited by 198 · see citing works

Effects of dietary cholesterol on serum cholesterol: a meta-analysis and review

Hopkins, P. N. (1992) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/55.6.1060 · Cited by 196 · see citing works

Bilberries reduce low‐grade inflammation in individuals with features of metabolic syndrome

Kolehmainen, M., Mykkänen, O. T., Kirjavainen, P. V., Leppänen, T., Moilanen, E., Adriaens, M. E., Laaksonen, D. E., Hallikainen, M., Puupponen‐Pimiä, R., Pulkkinen, L., et al. (2012) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201200195 · Cited by 194 · see citing works

Human metabolic correlates of body mass index

Moore, S. C., Matthews, C. E., Sampson, J. N., Stolzenberg‐Solomon, R. Z., Zheng, W., Cai, Q., Tan, Y. T., Chow, W., Ji, B., Liu, D., et al. (2013) · Metabolomics · doi:10.1007/s11306-013-0574-1 · Cited by 189 · see citing works

β-Sitosterol, β-Sitosterol Glucoside, and a Mixture of β-Sitosterol and β-Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells In Vitro and in Ovariectomized Athymic Mice

Ju, Y. H., Helferich, W. G., Clausen, L. M., Allred, K. F., & Almada, A. L. (2004) · Journal of Nutrition · doi:10.1093/jn/134.5.1145 · Cited by 185 · see citing works

Stanol/Sterol Ester–Containing Foods and Blood Cholesterol Levels

Lichtenstein, A. H., & Deckelbaum, R. J. (2001) · Circulation · doi:10.1161/01.cir.103.8.1177 · Cited by 183 · see citing works

No Association Between Plasma Levels of Plant Sterols and Atherosclerosis in Mice and Men

Wilund, K. R., Yu, L., Xu, F., Vega, G. L., Grundy, S. M., Cohen, J. C., & Hobbs, H. H. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000149140.00499.92 · Cited by 182 · see citing works

Introducing a new component of the metabolic syndrome: low cholesterol absorption

Simonen, P. P., Gylling, H., Howard, A. N., & Miettinen, T. A. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.1.82 · Cited by 181 · see citing works

Dietary -sitostanol related to absorption, synthesis and serum level of cholesterol in different apolipoprotein E phenotypes

Miettinen, T. A., & Vanhanen, H. (1994) · Atherosclerosis · doi:10.1016/0021-9150(94)90052-3 · Cited by 179 · see citing works

Cholesterol reduction by different plant stanol mixtures and with variable fat intake

Gylling, H., & Miettinen, T. A. (1999) · Metabolism · doi:10.1016/s0026-0495(99)90053-7 · Cited by 175 · see citing works

Alterations in cholesterol absorption/synthesis markers characterize Framingham Offspring Study participants with CHD

Matthan, N. R., Pencina, M. J., LaRocque, J. M., Jacques, P. F., D’Agostino, R. B., Schaefer, E. J., & Lichtenstein, A. H. (2009) · Journal of Lipid Research · doi:10.1194/jlr.p900039-jlr200 · Cited by 174 · see citing works

Diabetes Contributes to Cholesterol Metabolism Regardless of Obesity

Simonen, P. P., Gylling, H. K., & Miettinen, T. A. (2002) · Diabetes Care · doi:10.2337/diacare.25.9.1511 · Cited by 170 · see citing works

A Review of Dietary Phytochemicals and Their Relation to Oxidative Stress and Human Diseases

Guan, R., Van Le, Q., Yang, H., Zhang, D., Gu, H., Yang, Y., Sonne, C., Lam, S. S., Zhong, J., Jianguang, Z., et al. (2021) · Chemosphere · doi:10.1016/j.chemosphere.2020.129499 · Cited by 169 · see citing works

Highly sensitive analysis of sterol profiles in human serum by LC-ESI-MS/MS

Honda, A., Yamashita, K., Miyazaki, H., Shirai, M., Ikegami, T., Xu, G., Numazawa, M., Hara, T., & Matsuzaki, Y. (2008) · Journal of Lipid Research · doi:10.1194/jlr.d800017-jlr200 · Cited by 167 · see citing works

Lipid responses to plant-sterol-enriched reduced-fat spreads incorporated into a National Cholesterol Education Program Step I diet

Maki, K. C., Davidson, M. H., Umporowicz, D. M., Schaefer, E. J., Dicklin, M. R., Ingram, K. A., Chen, S., McNamara, J. R., Gebhart, B. W., Ribaya‐Mercado, J. D., et al. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.1.33 · Cited by 166 · see citing works

Independent association of serum squalene and noncholesterol sterols with coronary artery disease in postmenopausal women

Rajaratnam, R., Gylling, H. K., & Miettinen, T. A. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)00527-1 · Cited by 166 · see citing works

The rebound of lipoproteins after LDL-apheresis. Kinetics and estimation of mean lipoprotein levels

Kroon, A. A., Hof, M. A. V., Demacker, P. N. M., & Stalenhoef, A. F. H. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(00)00371-3 · Cited by 165 · see citing works

A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

Zhang, Y., Fu, Z.-Y., Wei, J. N., Qi, W., Baituola, G., Luo, J., Meng, Y. J., Guo, S., Yin, H., Jiang, S., et al. (2018) · Science · doi:10.1126/science.aao6575 · Cited by 163 · see citing works

Effect of intensive lipid lowering with atorvastatin on cardiovascular outcomes in coronary heart disease patients with mild-to-moderate baseline elevations in alanine aminotransferase levels

Tikkanen, M. J., Fayyad, R. S., Færgeman, O., OLSSON, A. G., Wun, C., Laskey, R. E., Kastelein, J. J. P., Holme, I., & Pedersen, T. R. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.06.024 · Cited by 160 · see citing works

Effects of inhibiting cholesterol absorption and synthesis on cholesterol and lipoprotein metabolism in hypercholesterolemic non-insulin-dependent diabetic men.

Gylling, H. K., & Miettinen, T. A. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39121-5 · Cited by 158 · see citing works

Vegetable oil based versus wood based stanol ester mixtures: effects on serum lipids and hemostatic factors in non-hypercholesterolemic subjects

Plat, J., & Mensink, R. P. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00261-0 · Cited by 157 · see citing works

Cholesterol synthesis is increased and absorption decreased in non-alcoholic fatty liver disease independent of obesity

Simonen, P. P., Kotronen, A., Hallikainen, M., Sevastianova, K., Makkonen, J., Hakkarainen, A., Lundbom, N. M. I., Miettinen, T. A., Gylling, H. K., & Yki‐Järvinen, H. (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.05.037 · Cited by 157 · see citing works

Stigmasterol reduces plasma cholesterol levels and inhibits hepatic synthesis and intestinal absorption in the rat

BATTA, A. K., Xu, G., Honda, A., Miyazaki, T., & Salen, G. (2006) · Metabolism · doi:10.1016/j.metabol.2005.08.024 · Cited by 156 · see citing works

Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity

Gylling, H. K., Hallikainen, M., Pihlajamäki, J., Ågren, J., Laakso, M., Rajaratnam, R., Rauramaa, R., & Miettinen, T. A. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m300522-jlr200 · Cited by 154 · see citing works

Rapid quantification of free and esterified phytosterols in human serum using APPI-LC-MS/MS

Lembcke, J., Ceglarek, U., Fiedler, M., Baumann, S., Leichtle, A. B., & Thiery, J. (2004) · Journal of Lipid Research · doi:10.1194/jlr.c400004-jlr200 · Cited by 152 · see citing works

New Insights Into the Genetic Regulation of Intestinal Cholesterol Absorption

Lammert, F., & WANG, D. (2005) · Gastroenterology · doi:10.1016/j.gastro.2004.11.017 · Cited by 145 · see citing works

Cholesterol absorption efficiency and sterol metabolism in obesity

Miettinen, T. A., & Gylling, H. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(00)00404-4 · Cited by 139 · see citing works

Synthesis and absorption markers of cholesterol in serum and lipoproteins during a large dose of statin treatment

Miettinen, T. A., & Gylling, H. (2003) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.2003.01229.x · Cited by 139 · see citing works

Plant-based sterols and stanols in health & disease: “Consequences of human development in a plant-based environment?”

Plat, J., Baumgartner, S., Vanmierlo, T., Lütjohann, D., Calkins, K. L., Burrin, D. G., Guthrie, G. J., Thijs, C. T., Velde, A. A. T., Vreugdenhil, A. C. E., et al. (2019) · Progress in Lipid Research · doi:10.1016/j.plipres.2019.02.003 · Cited by 138 · see citing works

Serum, biliary, and fecal cholesterol and plant sterols in colectomized patients before and during consumption of stanol ester margarine

Miettinen, T. A., Vuoristo, M., Nissinen, M. J., Järvinen, H., & Gylling, H. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.5.1095 · Cited by 138 · see citing works

Phytochemicals and Cardiovascular Disease

Howard, B. V., & Kritchevsky, D. (1997) · Circulation · doi:10.1161/01.cir.95.11.2591 · Cited by 138 · see citing works

Micellar distribution of cholesterol and phytosterols after duodenal plant stanol ester infusion

Nissinen, M. J., Gylling, H., Vuoristo, M., & Miettinen, T. A. (2002) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00446.2001 · Cited by 136 · see citing works

Apolipoprotein E Participates in the Regulation of Very Low Density Lipoprotein-Triglyceride Secretion by the Liver

Mensenkamp, A. R., Jong, M. C., van Goor, H., van Luyn, M. J. A., Bloks, V. W., Havinga, R., Voshol, P. J., Hofker, M. H., van Dijk, K. W., Havekes, L. M., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.50.35711 · Cited by 136 · see citing works

Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients

Kölsch, H., Heun, R., Kerksiek, A., von Bergmann, K., Maier, W., & Lütjohann, D. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.07.031 · Cited by 132 · see citing works

Canalicular ABC transporters and liver disease

Nicolaou, M., Andress, E. J., Zolnerciks, J. K., Dixon, P. H., Williamson, C., & Linton, K. J. (2011) · The Journal of Pathology · doi:10.1002/path.3019 · Cited by 131 · see citing works

Plasma Concentrations of Plant Sterols: Physiology and Relationship with Coronary Heart Disease

Chan, Y., Varady, K. A., Lin, Y., Trautwein, E. A., Mensink, R. P., Plat, J., & Jones, P. J. H. (2006) · Nutrition Reviews · doi:10.1111/j.1753-4887.2006.tb00224.x · Cited by 131 · see citing works

Influence of Drug Transporter Polymorphisms on Pravastatin Pharmacokinetics in Humans

Kivistö, K. T., & Niemi, M. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9159-2 · Cited by 130 · see citing works

Serum sterols during stanol ester feeding in a mildly hypercholesterolemic population

Gylling, H., Puska, P., Vartiainen, E. A., & Miettinen, T. A. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32138-6 · Cited by 130 · see citing works

Serum concentration and metabolism of cholesterol during rapeseed oil and squalene feeding

Miettinen, T. A., & Vanhanen, H. T. (1994) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/59.2.356 · Cited by 128 · see citing works

Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17

Niemi, M., Neuvonen, P. J., Hofmann, U., Backman, J. T., Schwab, M. G., Lütjohann, D., von Bergmann, K., Eichelbaum, M. F., & Kivistö, K. T. (2005) · Pharmacogenetics and Genomics · doi:10.1097/01213011-200505000-00005 · Cited by 125 · see citing works

24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases

Leoni, V., & Caccia, C. (2012) · Biochimie · doi:10.1016/j.biochi.2012.09.025 · Cited by 124 · see citing works

Vegan diet in young children remodels metabolism and challenges the statuses of essential nutrients

Hovinen, T., Korkalo, L., Freese, R., Skaffari, E., Isohanni, P., Niemi, M., Nevalainen, J., Gylling, H., Zamboni, N., Erkkola, M., et al. (2021) · EMBO Molecular Medicine · doi:10.15252/emmm.202013492 · Cited by 123 · see citing works

Effects of Hesperidin on the Progression of Hypercholesterolemia and Fatty Liver Induced by High-Cholesterol Diet in Rats

Wang, X., Hasegawa, J., Kitamura, Y., Wang, Z., Matsuda, A., Shinoda, W., Miura, N., & Kimura, K. (2011) · Journal of Pharmacological Sciences · doi:10.1254/jphs.11097fp · Cited by 121 · see citing works

Plasma levels of plant sterols and the risk of coronary artery disease: the prospective EPIC-Norfolk Population Study

Pinedo, S., Vissers, M. N., von Bergmann, K., El-Harchaoui, K., Lütjohann, D., Luben, R., Wareham, N. J., Kastelein, J. J. P., Khaw, K., & Boekholdt, S. M. (2006) · Journal of Lipid Research · doi:10.1194/jlr.m600371-jlr200 · Cited by 121 · see citing works

High Intestinal Cholesterol Absorption Is Associated With Cardiovascular Disease and Risk Alleles in ABCG8 and ABO

Silbernagel, G., Chapman, M. J., Genser, B., Kleber, M. E., Fauler, G., Scharnagl, H., Grammer, T. B., Boehm, B. O., Mäkelä, K.-M., Kähönen, M. A. P., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.01.100 · Cited by 119 · see citing works

Pronounced variation in bile acid synthesis in humans is related to gender, hypertriglyceridaemia and circulating levels of fibroblast growth factor 19

Gälman, C., Angelin, B., & Rudling, M. J. (2011) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2011.02466.x · Cited by 119 · see citing works

Impact of buttermilk consumption on plasma lipids and surrogate markers of cholesterol homeostasis in men and women

Conway, V., Couture, P., Richard, C., Gauthier, S., Pouliot, Y., & Lamarche, B. (2013) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2013.03.003 · Cited by 116 · see citing works

Alternate oils in fish feeds

Picková, J., & Mørkøre, T. (2007) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.200600222 · Cited by 116 · see citing works

Cholesterol-raising factor from boiled coffee does not pass a paper filter.

Dusseldorp, M., Katan, M., van Vliet, T., Demacker, P. N. M., & Stalenhoef, A. F. H. (1991) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.11.3.586 · Cited by 116 · see citing works

Metabolic variables of cholesterol during squalene feeding in humans: comparison with cholestyramine treatment

Strandberg, T., Tilvis, R., & Miettinen, T. (1990) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42347-8 · Cited by 115 · see citing works

Stanol Ester Margarine Alone and With Simvastatin Lowers Serum Cholesterol in Families With Familial Hypercholesterolemia Caused by the FH–North Karelia Mutation

Vuorio, A. F., Gylling, H., Turtola, H., KONTULA, K. K., Ketonen, P., & Miettinen, T. A. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.2.500 · Cited by 113 · see citing works

Cholesterol absorption decreases after Roux-en-Y gastric bypass but not after gastric banding

Pihlajamäki, J., Grönlund, S., Simonen, M., Käkelä, P., Moilanen, L., Pääkkönen, M. E., Pirinen, E., Kolehmainen, M., Kärjä, V. J., Kainulainen, S., et al. (2009) · Metabolism · doi:10.1016/j.metabol.2009.10.004 · Cited by 112 · see citing works

Inhibition of cholesterol absorption by plant sterols for mass intervention

Ikeda, I., & Sugano, M. (1998) · Current Opinion in Lipidology · doi:10.1097/00041433-199812000-00003 · Cited by 110 · see citing works

Sitosterolaemia: pathophysiology, clinical presentation and laboratory diagnosis

Kidambi, S., & Patel, S. B. (2008) · Journal of Clinical Pathology · doi:10.1136/jcp.2007.049775 · Cited by 110 · see citing works

Physiological and therapeutic factors affecting cholesterol metabolism: Does a reciprocal relationship between cholesterol absorption and synthesis really exist?

Santosa, S., Varady, K. A., AbuMweis, S. S., & Jones, P. J. H. (2006) · Life Sciences · doi:10.1016/j.lfs.2006.10.006 · Cited by 109 · see citing works

Impact of the SLCO1B1 polymorphism on the pharmacokinetics and lipid-lowering efficacy of multiple-dose pravastatin

Igel, M., ARNOLD, K., Niemi, M., Hofmann, U., Schwab, M. G., Lütjohann, D., VONBERGMANN, K., Eichelbaum, M. F., & Kivistö, K. (2006) · Clinical Pharmacology & Therapeutics · doi:10.1016/j.clpt.2006.01.010 · Cited by 108 · see citing works

Serum noncholesterol sterols during inhibition of cholesterol synthesis by statins

Miettinen, T. A., Gylling, H. K., Lindbohm, N., Miettinen, T. E., Rajaratnam, R., & Relas, H. (2003) · Journal of Laboratory and Clinical Medicine · doi:10.1067/mlc.2003.9 · Cited by 108 · see citing works

Cholesterol Absorption, Synthesis, and LDL Metabolism in NIDDM

Gylling, H., & Miettinen, T. A. (1997) · Diabetes Care · doi:10.2337/diacare.20.1.90 · Cited by 108 · see citing works

Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate–glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans

Oswald, S., Haenisch, S., Fricke, C., Sudhop, T., Remmler, C., Gießmann, T., Jedlitschky, G., Adam, U., Dazert, E., & Warzok, R. (2006) · Clinical Pharmacology & Therapeutics · doi:10.1016/j.clpt.2005.11.004 · Cited by 108 · see citing works

Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans

Bonde, Y., Breuer, O., Lütjohann, D., Sjöberg, S., Angelin, B., & Rudling, M. J. (2014) · Journal of Lipid Research · doi:10.1194/jlr.m051664 · Cited by 108 · see citing works

Comparison of the effects of maximal dose atorvastatin and rosuvastatin therapy on cholesterol synthesis and absorption markers

van Himbergen, T. M., Matthan, N. R., Resteghini, N. A., Otokozawa, S., Ai, M., Stein, E. A., Jones, P. H., & Schaefer, E. J. (2008) · Journal of Lipid Research · doi:10.1194/jlr.p800042-jlr200 · Cited by 106 · see citing works

The role of serum non-cholesterol sterols as surrogate markers of absolute cholesterol synthesis and absorption

Miettinen, T. A., Gylling, H., & Nissinen, M. J. (2011) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2011.05.005 · Cited by 105 · see citing works

Cholesterol metabolism in cholestatic liver disease and liver transplantation: From molecular mechanisms to clinical implications

Nemes, K., Åberg, F. O., Gylling, H., & Isoniemi, H. (2016) · World Journal of Hepatology · doi:10.4254/wjh.v8.i22.924 · Cited by 104 · see citing works

Effects of phytosterol ester-enriched margarine on plasma lipoproteins in mild to moderate hypercholesterolemia are related to basal cholesterol and fat intake

Mussner, M. J., Parhofer, K. G., von Bergmann, K., SCHWANDT, P., Broedl, U. C., & Otto, C. (2002) · Metabolism · doi:10.1053/meta.2002.29988 · Cited by 104 · see citing works

Decreased levels of the brain specific 24S-hydroxycholesterol and cholesterol precursors in serum of multiple sclerosis patients

Teunissen, C. E., Dijkstra, C. D., Polman, C. H., Hoogervorst, E. L. J., von Bergmann, K., & Lütjohann, D. (2003) · Neuroscience Letters · doi:10.1016/s0304-3940(03)00667-0 · Cited by 103 · see citing works

Serum plant sterols and their relation to cholesterol absorption

Tilvis, R. S., & Miettinen, T. A. (1986) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/43.1.92 · Cited by 328 · see citing works

Serum noncholesterol sterols related to cholesterol metabolism in familial hypercholesterolemia

Gylling, H., & Miettinen, T. A. (1988) · Clinica Chimica Acta · doi:10.1016/0009-8981(88)90267-7 · Cited by 37 · see citing works

Serum cholestanol and plant sterol levels in relation to cholesterol metabolism in middle-aged men

Miettinen, T. A., Tilvis, R. S., & Kesäniemi, Y. A. (1989) · Metabolism · doi:10.1016/0026-0495(89)90252-7 · Cited by 218 · see citing works

Plasma noncholesterol sterols as indicators of cholesterol absorption

Grundy, S. M. (2013) · Journal of Lipid Research · doi:10.1194/jlr.e036806 · Cited by 19 · see citing works

Fat-modified diets influence serum concentrations of cholesterol precursors and plant sterols in hypercholesterolemic subjects

Sarkkinen, E. S., Uusitupa, M. I. J., Gylling, H., & Miettinen, T. A. (1998) · Metabolism · doi:10.1016/s0026-0495(98)90040-3 · Cited by 28 · see citing works