The Role of Pain-Related Cognitions in the Relationship Between Pain Severity, Depression, and Pain Interference in a Sample of Primary Care Patients with Both Chronic Pain and Depression
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OBJECTIVE: The aims of this study were twofold: 1) to better understand the associations between pain-related cognitions and pain severity, and psychological and physical function, and 2) to determine the extent to which these cognitions function as mediators in the association between pain severity and depression in a sample of primary care adult patients with chronic pain and depression. DESIGN: Cross-sectional design. METHODS: Three hundred twenty-eight patients with both depression and chronic pain from primary care centers responded to measures of pain severity, pain interference, depression severity, and pain-related cognitions (including measures of catastrophizing and other pain-related beliefs). We performed three hierarchical regression analyses and two multiple regression analyses. RESULTS: The helplessness domain of pain catastrophizing was positively associated with pain severity, depression severity, and pain interference and mediated the relationship between depression and pain severity and vice versa. Beliefs about disability showed a positive association with pain severity, pain interference, and depression severity, and also mediated the relationship between pain severity and depression. Believing in a medical cure was positively associated with pain interference and negatively associated with depression; emotion beliefs were positively associated with pain severity. CONCLUSIONS: These findings provide important new information about the associations between several pain-related cognitions and pain severity, depression, and pain interference and the potential mediating roles that these cognitions play in the associations between pain severity and depression in patients with both chronic pain and depression in the primary care setting.
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Elevated levels of pain catastrophizing have been associated with increased pain intensity, depression and disability.
“As elevated levels of pain catastrophizing have been associated with increased pain intensity, depression and disability (Picavet et al., 2002;Sánchez-Rodríguez et al., 2020)”
From Exercise combined with Acceptance and Commitment Therapy for chronic pain: One-year follow-up from a randomized controlled trial (2024) · cites this paper as Sánchez-Rodríguez et al., 2020
The Pain catastrophizing section (page not provided) reports positive associations between the helplessness domain of catastrophizing and pain severity, depression severity, and pain interference. The claim is broader than that finding: the paper says the other catastrophizing domains did not show the same associations, and its Theoretical and clinical implications section says the total catastrophizing score was not significantly associated with depression severity in this sample. It measures pain interference rather than disability as such. (LLM, conf=0.84)
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Cited by
Sorted by citations
Casey, M. B., Takemasa, S., O'Reilly, T., Leamy, M., Mc Kearney, E., Buckley, M., Smart, K. M., Segurado, R., Lowry, D., Flanagan, D., et al. (2024) · European Journal of Pain · doi:10.1002/ejp.2229 · Cited by 4 · see citing works
- Authors
- Sánchez-Rodríguez, E., Aragonès, E., Jensen, M. P., Tomé-Pires, C., Rambla, C., López-Cortacans, G., & Miró, J.
- Affiliations
- Department of Psychology, Universitat Rovira i Virgili, Unit for the Study and Treatment of Pain – ALGOS, Research Center for Behavior Assessment (CRAMC), Catalonia, Spain
- Institut Universitari d'Investigació en Atenció Primària Jordi Gol (ES)
- University of Washington (US)
- Institut de Recerca Biomèdica Catalunya Sud (ES)
- Corresponding author
- Miró, Jordi
- Venue
- Pain Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2020-02-25
- Volume
- 21
- Issue
- 10
- Pages
- 2200-2211
- ISSN
- 1526-2375 (ISSN-L)
- 1526-4637
- OpenAlex
- W3007919548
- Cited by
- 38
- References
- 17
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 6 · 2023: 18 · 2022: 2 · 2021: 4
- FWCI
- 3.59
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Pain Medicine (publishedVersion)
- PubMed (publishedVersion)
- Rovira & Virgili repository (submittedVersion, cc-by)
- Funders
- Carlos III Health Institute of Spain’s Ministry of the Economy and Competitiveness (PI14/00573)
- European Regional Development Fund
- Carlos III Institute (INT15/00232)
- IDIAP Jordi Gol (7Z16/008, 2015)
- Universitat Rovira i Virgili
- Spanish Ministry of Economy and Competitiveness (RTI2018-09870-B-I00, RED2018-102546-T)
- Institució Catalana de Recerca i Estudis Avançats
- Fundación Grünenthal
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- pain-related cognitions, chronic pain, depression, pain intensity, pain interference, pain catastrophizing, helplessness, attitudes toward disability, emotion beliefs, mediation, primary care patients
- MeSH terms
- Adult, Cognition, Cross-Sectional Studies, Depression, Humans, Primary Health Care, Catastrophization, Chronic Pain
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