CoChat
Sign Up
Cited by 162Schizophrenia research and treatmentChild Abuse and TraumaPsychopathy, Forensic Psychiatry, Sexual Offending

Childhood sexual abuse, early cannabis use, and psychosis: Testing an interaction model based on the National Comorbidity Survey

Open access
Houston, J. E., Murphy, J., Adamson, G., Stringer, M., Shevlin, M.·2007·Schizophrenia Bulletin
DOI 10.1093/schbul/sbm127PMC PMC2632429
Open this paper in CoChat — free account

Abstract

Previous research investigating the etiology of psychosis has identified risk factors such as childhood sexual abuse and cannabis use. This study investigated the multiplicative effect of these variables on clinically assessed diagnoses of psychosis based on a large community sample (the National Comorbidity Survey). Demographic variables (sex, age, urbanicity, ethnicity, education, employment, and living arrangements) and depression were used as predictors in the first block of a binary logistic regression. In the second block, the variables representing early cannabis use, childhood sexual trauma, and the interaction between these variables were entered. There was no significant main effect for early cannabis use or childhood sexual trauma. The interaction was statistically significant (odds ratio [OR] = 6.93, 95% confidence interval [CI] = 1.39-34.63, P = .02). The effect for the sexual trauma variable was statistically significant for those who used cannabis under 16 years (OR = 11.96, 95% CI = 2.10-68.22, P = .01) but not for those who had not used cannabis under 16 years (OR = 1.80, 95% CI = 0.91-3.57, P = .09). Many factors have been shown to be significant in the etiology of psychosis; however, the current research augments previous findings by examining psychosis in terms of an interaction between 2 of these factors.

Integrity signals

Registry

Crossref · 10.1093/schbul/sbm127

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Three studies have found that presence of both childhood trauma and cannabis use increased the absolute risk of psychosis to a greater degree than the sum of either risk factor alone.

    “Three studies have found that presence of both childhood trauma and cannabis use increased the absolute risk of psychosis to a greater degree than the sum of either risk factor alone (42)(43)(44).”

    From Association Between Cannabis and Psychosis: Epidemiologic Evidence (2016) · cites this paper as [44]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Houston, J. E., Murphy, J., Adamson, G., Stringer, M., & Shevlin, M.
Affiliations
  • University of Ulster (GB)
  • Nottingham Trent University (GB)
ORCID
Venue
Schizophrenia Bulletin
Publisher
Oxford University Press (OUP)
Published
2007-05-04
Volume
34
Issue
3
Pages
580-585
ISSN
  • 0586-7614 (ISSN-L)
  • 1745-1701
DOI
10.1093/schbul/sbm127
PMC
PMC2632429
OpenAlex
W2161482219
Cited by
162
References
37
Citations by year
2025: 6 · 2024: 1 · 2023: 8 · 2022: 5 · 2021: 3 · 2020: 8 · 2019: 13 · 2018: 6 · 2017: 14 · 2016: 8 · 2015: 12 · 2014: 13 · 2013: 12 · 2012: 15
FWCI
4.24
Type
journal article
Language
en
Open access
Locations
  • Schizophrenia Bulletin (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Nottingham Trent University's Institutional Repository (Nottingham Trent Repository) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
  • Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
Keywords
child sexual abuse
MeSH terms
Adolescent, Adult, Age Factors, Marijuana Abuse, Child, Child Abuse, Sexual, Female, Humans, Male, Middle Aged, Psychotic Disorders, Surveys and Questionnaires, Comorbidity, Prevalence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review