Psychophysiological responses in ADHD boys with and without conduct disorder: implications for adult antisocial behavior
Abstract
Objective Several studies have demonstrated that the presence of attention-deficit/hyperactivity disorder (ADHD) in childhood increases the risk of antisocial behavior developing in adulthood. However, because previous research did not consider comorbid conduct disorder (CD), the question of whether ADHD by itself or only the association of ADHD with CD implies a risk of adult antisocial behavior developing is still under discussion.Method Because several characteristics of psychophysiological response had been shown to be associated with future increased likelihood of adult antisocial behavior, autonomic arousal as well as electrodermal responses to orienting and aversive stimuli were assessed in 26 boys with ADHD+CD compared with 21 boys with ADHD alone and 21 controls.Results Boys with a comorbid condition of ADHD+CD showed a decrement of autonomic responses and a more rapid habituation to orienting and aversive startling stimuli compared with age-matched children with ADHD alone.Conclusions Boys with ADHD+CD show a psychophysiological response pattern that is very similar to that reported in antisocial personalities. These findings give further support for a high persistence of antisocial behavior from childhood to adulthood, while no evidence was found that ADHD itself is associated with a predisposition to antisocial behavior.
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Three of the EDA studies reporting hypo-activation of the ANS in ADHD used either passive and/or active auditory attention tasks.
“Of the studies reporting hypo-activation of the ANS, three used either passive and/or active auditory attention tasks (Herpertz et al., 2001(Herpertz et al., , 2003;;Shibagaki et al., 1993).”
From Is autonomic nervous system function atypical in Attention Deficit Hyperactivity Disorder (ADHD)? A systematic review of the evidence (2020) · cites this paper as Herpertz et al., 2001
Herpertz et al. (2001;2003) found reduced skin conductance responses (SCRs) and delayed habituation of SCRs to auditory tones during a passive attention task, but this effect was only significant when comparing children with ADHD + CD to typical controls; no differences were found between controls and children with ADHD-only.
“The studies of Herpertz et al. (2001;2003), described in paragraphs 3.1.1and 3.1.2,similarly found reduced skin conductance responses (SCRs) and delayed habituation of SCRs to auditory tones during a passive attention task, but this effect was only significant when comparing children with ADHD + CD to typical controls (no differences were found between controls and children with ADHD-only).”
From Is autonomic nervous system function atypical in Attention Deficit Hyperactivity Disorder (ADHD)? A systematic review of the evidence (2020) · cites this paper as Herpertz et al., 2001
In Herpertz et al. (2001a), ADHD+CD = ADHD = TD on resting mean HR.
“ADHD + CD = ADHD = TD on resting mean HR”
From Is autonomic nervous system function atypical in Attention Deficit Hyperactivity Disorder (ADHD)? A systematic review of the evidence (2020) · cites this paper as Herpertz et al., 2001 a
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- Authors
- HERPERTZ, S. C., WENNING, B., MUELLER, B., QUNAIBI, M., SASS, H., & HERPERTZ-DAHLMANN, B.
- Affiliations
- RWTH Aachen University (DE)
- Corresponding author
- HERPERTZ, SABINE C.
- Venue
- Journal of the American Academy of Child & Adolescent Psychiatry
- Publisher
- Elsevier BV
- Published
- 2001-10
- Volume
- 40
- Issue
- 10
- Pages
- 1222-1230
- ISSN
- 0890-8567 (ISSN-L)
- OpenAlex
- W2084145685
- Cited by
- 126
- References
- 43
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 3 · 2020: 5 · 2019: 4 · 2018: 4 · 2017: 4 · 2016: 4 · 2015: 7 · 2014: 3 · 2013: 9 · 2012: 6
- FWCI
- 3.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- RWTH Publications (RWTH Aachen) (submittedVersion)
- Funders
- DFG (grant HE 2660/3-1)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- attention deficit hyperactivity disorder, conduct disorder, comorbidities, antisocial personality, psychophysiological responses, autonomic arousal, electrodermal activity, orienting response, aversive stimuli, habituation
- MeSH terms
- Adolescent, Adult, Antisocial Personality Disorder, Arousal, Attention Deficit Disorder with Hyperactivity, Autonomic Nervous System, Child, Germany, Humans, Male, Orientation, Reflex, Startle, Comorbidity, Multivariate Analysis, Case-Control Studies, Conduct Disorder
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