Investigation of autonomic nervous system functions by pupillometry in children with Attention-Deficit/Hyperactivity disorder
Open accessAbstract
Objective: Attention deficit hyperactivity disorder (ADHD) is one of the most frequently seen neurodevelopmental disorders among school-aged children. Although the main cause of ADHD is unknown, combinations of genetic, biological and psychosocial factors are thought to play a part in the etiology of ADHD. This study aims to compare the autonomic nervous system functions of 6–11 year-old males diagnosed with ADHD against healthy controls by measuring pupil diameters.Methods: Thirty-two males with ADHD and 24 healthy controls participated in this study. Any other psychiatric disorders except oppositional defiant disorder (ODD) were excluded from this study. The autonomic nervous system functions of participants were evaluated by measuring pupil diameter changes in photopic and mesopic conditions.Results: There were no statistically significant difference on photopic and mesopic pupil diameters between the ADHD and healthy control groups. Moreover, the ADHD subgroup with ODD did not differ from the ADHD subgroup without ODD with respect to the same parameters.Conclusion: In conclusion, these findings suggest that males with ADHD show no differences in pupil diameters compared to typically developing children. This might indicate no difference in autonomic nervous system functions measured by pupillometry. However, it is recommended that the results of our study need to be confirmed by more detailed studies.
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In Kara et al. (2013), ADHD = CTRL on pupil diameter during resting-state.
“ADHD = CTRL”
From Is autonomic nervous system function atypical in Attention Deficit Hyperactivity Disorder (ADHD)? A systematic review of the evidence (2020) · cites this paper as Kara et al., 2013
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- Authors
- Kara, K., Karaman, D., Erdem, U., Congologlu, M. A., Durukan, I., & Ilhan, A.
- Affiliations
- Gulhane Military Academy, School of Medicine Department of Child and Adolescent Psychiatry, Ankara - Turkey
- Gulhane Military Academy, School of Medicine Department of Ophthalmology, Ankara - Turkey
- Corresponding author
- Kara, Koray
- Venue
- Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology
- Publisher
- Informa UK Limited
- Published
- 2013-03
- Volume
- 23
- Issue
- 1
- Pages
- 49-56
- ISSN
- 1017-7833 (ISSN-L)
- 1302-9657
- OpenAlex
- W2113756683
- Cited by
- 14
- References
- 36
- Citations by year
- 2025: 2 · 2024: 1 · 2022: 2 · 2021: 2 · 2020: 3 · 2019: 3 · 2018: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- Licence
- cc-by-nc
- Locations
- Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology (publishedVersion)
- Psychiatry and Clinical Psychopharmacology (publishedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- attention deficit hyperactivity disorder, autonomic nervous system, pupillometry, pupil size, oppositional defiant disorder, children, neurodevelopmental disorders
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