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Cited by 73Youth Substance Use and School AttendanceAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychological Treatments and Assessments

Predictors of treatment response in anxious-depressed adolescents with school refusal

LAYNE, ANN E., BERNSTEIN, GAIL A., EGAN, ELIZABETH A., KUSHNER, MATT G.·2003·Journal of the American Academy of Child & Adolescent Psychiatry
DOI 10.1097/00004583-200303000-00012
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Abstract

Objective To identify predictors of treatment response to 8 weeks of cognitive-behavioral therapy (CBT) among anxious-depressed adolescents with school refusal, half of whom received imipramine plus CBT and half of whom received placebo plus CBT.Method A hierarchical multiple regression analysis was used to evaluate the following variables as potential predictors of treatment response as measured by school attendance at the end of treatment: baseline severity (school attendance at baseline), drug group (imipramine versus placebo), presence of separation anxiety disorder (SAD), and presence of avoidant disorder (AD).Results Baseline attendance, CBT plus imipramine, SAD, and AD were significant predictors of treatment response and accounted for 51% of the variance in outcome. Specifically, a higher rate of attendance at baseline and receiving imipramine predicted a better response to treatment whereas the presence of SAD and AD predicted a poorer response to treatment. The relationship between sociodemographic variables and treatment outcome was also evaluated. Age and socioeconomic status were unrelated to school attendance after treatment. Males had significantly higher rates of attendance after treatment than females.Conclusions Adolescents with school refusal are a heterogeneous population and require individualized treatment planning. Variables such as diagnosis and severity at the start of treatment should be taken into consideration when planning treatment.

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Authors
LAYNE, A. E., BERNSTEIN, G. A., EGAN, E. A., & KUSHNER, M. G.
Affiliations
University of Minnesota (US)
Corresponding author
LAYNE, ANN E.
ORCID
Venue
Journal of the American Academy of Child & Adolescent Psychiatry
Publisher
Elsevier BV
Published
2003-03
Volume
42
Issue
3
Pages
319-326
ISSN
0890-8567 (ISSN-L)
DOI
10.1097/00004583-200303000-00012
OpenAlex
W2008520520
Cited by
73
References
58
Citations by year
2026: 1 · 2025: 1 · 2024: 1 · 2023: 3 · 2022: 4 · 2021: 2 · 2020: 4 · 2019: 2 · 2018: 4 · 2017: 3 · 2016: 4 · 2015: 5 · 2014: 4 · 2013: 6 · 2012: 6
FWCI
17.53
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Education › Youth Substance Use and School Attendance
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
Keywords
school refusal, cognitive behavioral therapy, imipramine, predictors of treatment response, separation anxiety disorder, school attendance, baseline severity, sex differences in treatment outcomes
MeSH terms
Adolescent, Adolescent Behavior, Antidepressive Agents, Tricyclic, Anxiety Disorders, Child, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Imipramine, Male, Prospective Studies, Regression Analysis, Student Dropouts, Cognitive Behavioral Therapy, Single-Blind Method

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