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Cited by 288Posttraumatic Stress Disorder ResearchHeart Rate Variability and Autonomic ControlCardiac Health and Mental Health

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A Meta-Analytic Examination of Basal Cardiovascular Activity in Posttraumatic Stress Disorder

Buckley, Todd C., Kaloupek, Danny G.·2001·Psychosomatic Medicine
DOI 10.1097/00006842-200107000-00011
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Abstract

Objective The objective of this meta-analytic study was to determine whether individuals with posttraumatic stress disorder (PTSD) have higher levels of basal cardiovascular activity relative to comparable groups of individuals without PTSD. Methods Meta-analytic data methods were applied to 34 studies that gathered indicators of basal cardiovascular activity including: heart rate (HR), systolic blood pressure, and diastolic blood pressure on subjects diagnosed with PTSD and two types of comparison groups. In total, cardiovascular measures were analyzed for 2670 subjects across all studies. Results Results indicate that individuals with a current PTSD diagnosis have higher resting HR relative to both trauma-exposed individuals without a PTSD diagnosis and non-trauma-exposed individuals. The results also suggest that PTSD is associated with elevations in blood pressure; however, the effect sizes were smaller in magnitude than those obtained for heart rate. A subset analysis revealed that the effect sizes for comparisons on basal HR were greatest in studies with the most chronic PTSD samples. Conclusion The meta-analysis supports previous qualitative reviews, finding a positive association between PTSD and basal cardiovascular activity. The discussion addresses possible mechanisms of action and the health-related implications of these findings.

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Citations

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Metadata

Authors
Buckley, T. C., & Kaloupek, D. G.
Affiliations
Boston University (US)
ORCID
Kaloupek, Danny G.
Venue
Psychosomatic Medicine
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2001-07
Volume
63
Issue
4
Pages
585-594
ISSN
0033-3174 (ISSN-L)
DOI
10.1097/00006842-200107000-00011
OpenAlex
W2097383944
Cited by
288
References
9
Citations by year
2026: 5 · 2025: 6 · 2024: 6 · 2023: 10 · 2022: 7 · 2021: 13 · 2020: 14 · 2019: 15 · 2018: 7 · 2017: 10 · 2016: 20 · 2015: 12 · 2014: 11 · 2013: 22 · 2012: 17
FWCI
1.70
Type
journal article
Language
en
Open access
closed
Locations
  • Psychosomatic Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords
post-traumatic stress disorder, resting heart rate, blood pressure, systolic blood pressure, diastolic blood pressure, trauma exposure, chronic PTSD, autonomic nervous system, cardiovascular reactivity
MeSH terms
Arousal, Blood Pressure, Cardiovascular System, Heart Rate, Humans, Stress Disorders, Post-Traumatic

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