Impact of Comorbid Panic and Posttraumatic Stress Disorder on Outcomes of Collaborative Care for Late-Life Depression in Primary Care
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The treatment literature indicates that the combination of anxiety and depression is more difficult to treat, with greater risk of relapse and poorer treatment response, than either alone.
“The treatment literature indicates that the combination of anxiety and depression is more difficult to treat, with greater risk of relapse and poorer treatment response, than either alone [25,26]”
From A longitudinal study of affective and anxiety disorders, depressive affect and diabetes distress in adults with type 2 diabetes (2008) · cites this paper as [26]
Poor PTSD treatment outcomes are associated with comorbid conditions including childhood trauma, alcohol and substance use disorders, depression, suicidal ideation and dissociation.
“poor PTSD treatment outcomes are associated with several comorbid conditions that include childhood trauma2, alcohol and substance use disorders3, depression4, suicidal ideation5 and dissociation6.”
From MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study (2021) · cites this paper as [4]
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Self-citationMultiple Imputation for Nonresponse in Surveys
Rubin, D. B. (1987) · Wiley Series in Probability and Statistics · doi:10.1002/9780470316696 · Cited by 20,701 · see citing works
Littell, R. C. (1996) · Medical Entomology and Zoology · Cited by 10,345 · see citing works
Diagnostic and Statistical Manual of Mental Disorders, 5th Edition
(2013) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9780890425596.893619 · Cited by 4,390 · see citing works
SCL-90: an outpatient psychiatric rating scale--preliminary report.
Derogatis, L. R., Lipman, R. S., & Covi, L. (1973) · PubMed · Cited by 3,815 · see citing works
Mendelson, G. (1995) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048679509064964 · Cited by 2,592 · see citing works
Unützer, J., Katon, W., Callahan, C. M., Williams, Jr., Hunkeler, E., Harpole, L., Hoffing, M., Della Penna, R. D., Noël, P. H., Lin, E. H. B., et al. (2002) · JAMA · doi:10.1001/jama.288.22.2836 · Cited by 2,405 · see citing works
Self-citationMultiple Imputation for Nonresponse in Surveys.
Lynn, P. J., & Rubin, D. B. (1988) · Journal of the Royal Statistical Society Series D (The Statistician) · doi:10.2307/2348774 · Cited by 2,330 · see citing works
The CAGE Questionnaire: Validation of a New Alcoholism Screening Instrument
Mayfield, D. G., McLeod, G. A., & Hall, P. B. (1974) · American Journal of Psychiatry · doi:10.1176/ajp.131.10.1121 · Cited by 2,261 · see citing works
Six-item screener to identify cognitive impairment among potential subjects for clinical research
Callahan, C. M., Unverzagt, F. W., Hui, S. L., Perkins, A. J., & Hendrie, H. C. (2002) · Medical Care · doi:10.1097/00005650-200209000-00007 · Cited by 1,499 · see citing works
Sheehan, D. V., Harnett-Sheehan, K., & Raj, B. A. (1996) · International Clinical Psychopharmacology · doi:10.1097/00004850-199606003-00015 · Cited by 1,440 · see citing works
Missing-Data Adjustments in Large Surveys
Little, R. J. A. (1988) · Journal of Business and Economic Statistics · doi:10.1080/07350015.1988.10509663 · Cited by 1,109 · see citing works
The inventory for depressive symptomatology (IDS): Preliminary findings
Rush, A. J., Giles, D. E., Schlesser, M. A., Fulton, C. L., Weissenburger, J. E., & Burns, C. (1986) · Psychiatry Research · doi:10.1016/0165-1781(86)90060-0 · Cited by 908 · see citing works
Service utilization and social morbidity associated with depressive symptoms in the community
Johnson, J. (1992) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1992.03480110054033 · Cited by 726 · see citing works
The impact of psychiatric disorders on work loss days
Kessler, R. C., & Frank, R. G. (1997) · Psychological Medicine · doi:10.1017/s0033291797004807 · Cited by 716 · see citing works
Wang, P. S., Berglund, P., & Kessler, R. C. (2000) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2000.9908044.x · Cited by 686 · see citing works
Sartorius, N., Üstün, T. B., Lecrubier, Y., & Wittchen, H.-U. (1996) · British Journal of Psychiatry · doi:10.1192/s0007125000298395 · Cited by 541 · cited 1× · see citing works
“92 [2 5 7 ] 0.”
Prevalence of anxiety disorders and their comorbidity with mood and addictive disorders
Regier, D. A., Rae, D. S., Narrow, W. E., Kaelber, C. T., & Schatzberg, A. F. (1998) · British Journal of Psychiatry · doi:10.1192/s0007125000293483 · Cited by 407 · see citing works
Sex differences in depression: a role for preexisting anxiety
Breslau, N., Schultz, L. R., & Peterson, E. (1995) · Psychiatry Research · doi:10.1016/0165-1781(95)02765-o · Cited by 355 · see citing works
Comorbid anxiety disorders in depressed elderly patients.
Lenze, E., Mulsant, B., Shear, M., Schulberg, H. C., Dew, M., Begley, A., Pollock, B., & Reynolds, C. F. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.722 · Cited by 327 · see citing works
Treatment outcomes for primary care patients with major depression and lifetime anxiety disorders.
(1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.10.1293 · Cited by 312 · see citing works
A multiple imputation strategy for clinical trials with truncation of patient data
Lavori, P. W., Dawson, R., & Shera, D. M. (1995) · Statistics in Medicine · doi:10.1002/sim.4780141707 · Cited by 291 · see citing works
Prevalence, nature, and comorbidity of depressive disorders in primary care
Coyne, J. C., Fechner-Bates, S., & Schwenk, T. L. (1994) · General Hospital Psychiatry · doi:10.1016/0163-8343(94)90006-x · Cited by 281 · see citing works
Temporal Profiles of the Course of Depression During Treatment
Dew, M. A. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830230050007 · Cited by 273 · see citing works
Davidson, J. R. T., Pearlstein, T., Londborg, P., Brady, K. T., Rothbaum, B., Bell, J., Maddock, R., Hegel, M. T., & Farfel, G. M. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.12.1974 · Cited by 219 · see citing works
Self-citationBartels, S. J., Coakley, E., Oxman, T. E., Constantino, G., Oslin, D., Chen, H., Zubritsky, C., Cheal, K., Durai, U. N. B., Gallo, J. J., et al. (2002) · The American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200207000-00008 · Cited by 216 · see citing works
Anxiety syndromes as epiphenomena of primary major depression: outcome and familial psychopathology
Coryell, W. H., Endicott, J., & Winokur, G. (1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.1.100 · Cited by 137 · see citing works
Sertraline Treatment of Posttraumatic Stress Disorder
Londborg, P. D., Hegel, M. T., Goldstein, S., Goldstein, D., Himmelhoch, J. M., Maddock, R. J., Patterson, W. M., Rausch, J. L., & Farfel, G. M. (2001) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v62n0503 · Cited by 136 · see citing works
Self-citationAnxiety and Its Association With Depression Among Institutionalized Elderly
Parmelee, P. A., Katz, I. R., & Lawton, M. P. (1993) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-199300110-00007 · Cited by 125 · see citing works
Anxiety Disorders: Similarities and Differences of Comorbidity in Treated and Untreated Groups
Wïttchen, H., Essau, C. A., & Krieg, J.-C. (1991) · The British Journal of Psychiatry · doi:10.1192/s0007125000296219 · Cited by 117 · see citing works
Gaynes, B. N., Magruder, K. M., Burns, B. J., Wagner, H. R., Yarnall, K. S. H., & Broadhead, W. E. (1999) · General Hospital Psychiatry · doi:10.1016/s0163-8343(99)00005-5 · Cited by 116 · see citing works
Anxious Depression in Elderly Patients: Response to Antidepressant Treatment
Flint, A. J., & Rifat, S. L. (1997) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-199700520-00003 · Cited by 113 · see citing works
Zayfert, C., Citters, A. D. V., Ferguson, R. J., & Hegel, M. T. (2002) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200204000-00004 · Cited by 112 · see citing works
Self-citationCourse of depression in patients with comorbid anxiety disorders
Sherbourne, C. D., & Wells, K. B. (1997) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)01442-0 · Cited by 109 · see citing works
Frank, E., Shear, M., Rucci, P., Cyranowski, J., Endicott, J., Fagiolini, A., Grochocinski, V., Houck, P., Kupfer, D. J., Maser, J., et al. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.7.1101 · Cited by 107 · see citing works
Social support and treatment response in older depressed primary care patients
Oxman, T. E., & Hull, J. G. (2001) · The Journals of Gerontology Series B: Psychological Sciences and Social Sciences · doi:10.1093/geronb/56.1.p35 · Cited by 95 · see citing works
Hegel, M. T., Imming, J., Cyr‐Provost, M., Noël, P. H., Areán, P. A., & Unützer, J. (2002) · Families Systems & Health · doi:10.1037/h0089475 · Cited by 66 · see citing works
Self-citationSchatzberg, A. F., SAMSON, J. A., Rothschild, A. J., Bond, T. C., & Regier, D. A. (1998) · The British Journal of Psychiatry · doi:10.1192/s0007125000293495 · Cited by 56 · see citing works
The management of panic disorder.
Sheehan, D. V. (2002) · PubMed · Cited by 27 · see citing works
LADER, M. H. (2005) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.5.2.259 · Cited by 18 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Collaborative care for depression and anxiety problems
Archer, J., Bower, P., Gilbody, S., Lovell, K., Richards, D., Gask, L., Dickens, C., & Coventry, P. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006525.pub2 · Cited by 1,126 · see citing works
MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study
Mitchell, J. M., Bogenschutz, M., Lilienstein, A., Harrison, C., Kleiman, S., Parker-Guilbert, K., Ot’alora G., M., Garas, W., Paleos, C., Gorman, I., et al. (2021) · Nature Medicine · doi:10.1038/s41591-021-01336-3 · Cited by 1,004 · see citing works
Anxiety disorders in older adults: a comprehensive review
Wolitzky-Taylor, K. B., Castriotta, N., Lenze, E. J., Stanley, M. A., & Craske, M. G. (2010) · Depression and Anxiety · doi:10.1002/da.20653 · Cited by 726 · see citing works
Fisher, L., Skaff, M. M., Mullan, J. T., Arean, P., Glasgow, R., & Masharani, U. (2008) · Diabetic Medicine · doi:10.1111/j.1464-5491.2008.02533.x · Cited by 524 · see citing works
Campbell, D. G., Felker, B. L., Liu, C.-F., Yano, E. M., Kirchner, J. E., Chan, D., Rubenstein, L. V., & Chaney, E. F. (2007) · Journal of General Internal Medicine · doi:10.1007/s11606-006-0101-4 · Cited by 458 · see citing works
McAllister-Williams, R. H., Arango, C., Blier, P., Demyttenaere, K., Falkai, P., Gorwood, P., Hopwood, M., Javed, A., Kasper, S., Malhi, G. S., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.02.023 · Cited by 278 · see citing works
Burroughs, H. (2006) · Family Practice · doi:10.1093/fampra/cmi115 · Cited by 220 · see citing works
Posttraumatic Stress Disorder in Older Adults: A Conceptual Review
Pless Kaiser, A., Cook, J. M., Glick, D. M., & Moye, J. (2019) · Clinical Gerontologist · doi:10.1080/07317115.2018.1539801 · Cited by 175 · see citing works
“Treatment response to depression has been slower (Hegel et al., 2005), and worse (Clark, Rouse, Spangler, & Moye, 2018) for older adults with comorbid PTSD. Substance abuse and partial or full PTSD can also co-occur, although evidence is inconsistent for older adults (Pietrzak et al., 2012b).”
BackgroundWaitzkin, H., Getrich, C., Heying, S., Rodríguez, L., Parmar, A., Willging, C., Yager, J., & Santos, R. (2011) · Journal of Community Health · doi:10.1007/s10900-010-9313-y · Cited by 98 · see citing works
MDMA-Assisted Therapy for Severe PTSD: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study
Mitchell, J. M., Bogenschutz, M., Lilienstein, A., Harrison, C., Kleiman, S., Parker-Guilbert, K., Ot’alora G, M., Garas, W., Paleos, C., Gorman, I., et al. (2023) · Focus · doi:10.1176/appi.focus.23021011 · Cited by 93 · see citing works
Pomerantz, A. S., Corson, J. A., & Detzer, M. J. (2009) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-009-9147-x · Cited by 76 · see citing works
Treatment Initiation for New Episodes of Depression in Primary Care Settings
Waitzfelder, B., Stewart, C., Coleman, K. J., Rossom, R., Ahmedani, B. K., Beck, A., Zeber, J. E., Daida, Y. G., Trinacty, C., Hubley, S., et al. (2018) · Journal of General Internal Medicine · doi:10.1007/s11606-017-4297-2 · Cited by 73 · see citing works
Wuthrich, V. M., & Rapee, R. M. (2013) · Behaviour Research and Therapy · doi:10.1016/j.brat.2013.09.002 · Cited by 71 · see citing works
Psychiatric comorbidity and depression in older adults
Gum, A. M., & Cheavens, J. S. (2008) · Current Psychiatry Reports · doi:10.1007/s11920-008-0006-5 · Cited by 40 · see citing works
Wozney, L., Olthuis, J., Lingley-Pottie, P., McGrath, P. J., Chaplin, W., Elgar, F., Cheney, B., Huguet, A., Turner, K., & Kennedy, J. (2017) · Archives of Women's Mental Health · doi:10.1007/s00737-017-0732-y · Cited by 33 · see citing works
Dombrovski, A. Y., Blakesley-Ball, R. E., Mulsant, B. H., Mazumdar, S., Houck, P. R., Szanto, K., & Reynolds, C. F. (2006) · The American Journal of Geriatric Psychiatry · doi:10.1097/01.jgp.0000218325.76196.d1 · Cited by 27 · see citing works
- Authors
- Hegel, M. T., Unützer, J., Tang, L., Areán, P. A., Katon, W., Noël, P. H., Williams, J. W., & Lin, E. H. B.
- Affiliations
- Dartmouth College (US)
- University of California, Los Angeles (US)
- Corresponding author
- Hegel, Mark T.
- ORCID
- Venue
- The American Journal of Geriatric Psychiatry
- Publisher
- Elsevier BV
- Published
- 2005-01
- Volume
- 13
- Issue
- 1
- Pages
- 48-58
- ISSN
- 1064-7481 (ISSN-L)
- OpenAlex
- W2070205822
- Cited by
- 114
- References
- 40
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 2 · 2022: 2 · 2021: 4 · 2020: 7 · 2019: 4 · 2018: 6 · 2017: 4 · 2016: 4 · 2015: 6 · 2014: 6 · 2013: 6 · 2012: 8
- FWCI
- 10.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Geriatric Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- California Health Care Foundation
- Hogg Foundation for Mental Health
- Robert Wood Johnson Foundation
- John A. Hartford Foundation
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- geriatric depression, panic disorder, post-traumatic stress disorder, comorbid anxiety disorders, collaborative care, primary care, older adults, treatment response, usual care comparison
- MeSH terms
- Age Factors, Aged, Combined Modality Therapy, Demography, Major Depressive Disorder, Depressive Disorder, Major, Drug Therapy, Female, Follow-Up Studies, Health Services Accessibility, Health Services for the Aged, Humans, Male, Mental Health Services, Patient Care Team, Primary Health Care, Psychotherapy, Brief, Severity of Illness Index, Stress Disorders, Post-Traumatic, Comorbidity, Panic Disorder, Outcome Assessment, Health Care
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
