Comorbidity of irritable bowel syndrome in psychiatric patients: A review

Garakani, Amir; Win, Terrance; Virk, Subhdeep; Gupta, Sanjay; Kaplan, David; Masand, Prakash S.

doi:10.1097/00045391-200301000-00014

Cited by 149Gastrointestinal motility and disordersPsychosomatic Disorders and Their TreatmentsInfant Health and Development

Comorbidity of irritable bowel syndrome in psychiatric patients: A review

Garakani, Amir, Win, Terrance, Virk, Subhdeep, Gupta, Sanjay, Kaplan, David, Masand, Prakash S.·2003·American Journal of Therapeutics

DOI 10.1097/00045391-200301000-00014

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Abstract

Irritable bowel syndrome (IBS), a functional gastrointestinal disorder, is present in 10% to 20% of the U.S. adult population. The syndrome is best defined as chronic abdominal discomfort with changes in stool frequency, consistency, and passage, with associated symptoms such as abdominal bloating or presence of mucus in stools. Several studies have shown that up to 70% to 90% of patients with IBS who seek treatment have psychiatric comorbidity, most notably mood and anxiety disorders. Recent studies have shown a high prevalence of IBS in psychiatric patients who seek treatment, with a prevalence of 19% in schizophrenia, 29% in major depression, and 46% in panic disorder among other disorders. Our article reviews the comorbidity of IBS in psychiatric patients and discusses implications for treatment.

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There is a high prevalence of co-morbidity between psychiatric and gastrointestinal symptoms, with 40-60% of patients with functional gastrointestinal disorders experiencing psychiatric symptoms and up to 50% of psychiatric patients diagnosed with irritable bowel syndrome.
“There is a high prevalence of co-morbidity between psychiatric and gastrointestinal symptoms, e.g., 40–60% of patients with functional gastrointestinal disorders experience psychiatric symptoms [35] and up to 50% of psychiatric patients are diagnosed with irritable bowel syndrome [36], which clearly suggests broader implications of this axis on gastrointestinal and brain functions.”
From Are the gut bacteria telling us to eat or not to eat? reviewing the role of gut microbiota in the etiology, disease progression and treatment of eating disorders (2017) · cites this paper as [36]

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Authors: Garakani, A., Win, T., Virk, S., Gupta, S., Kaplan, D., & Masand, P. S.
Affiliations: Icahn School of Medicine at Mount Sinai (US)
Olean General Hospital (US)
Corresponding author: Masand, Prakash S.
ORCID: Garakani, Amir
Virk, Subhdeep
Masand, Prakash S.
Venue: American Journal of Therapeutics
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2003-01
Volume: 10
Issue: 1
Pages: 61-67
ISSN: 1075-2765 (ISSN-L)
DOI: 10.1097/00045391-200301000-00014
OpenAlex: W2041184383
Cited by: 149
References: 49
Citations by year: 2026: 1 · 2025: 2 · 2024: 6 · 2023: 3 · 2022: 1 · 2021: 4 · 2020: 7 · 2019: 4 · 2018: 7 · 2017: 12 · 2016: 14 · 2015: 12 · 2014: 8 · 2013: 3 · 2012: 8
FWCI: 0.96
Type: journal article
Language: en
Open access: closed
Locations: American Journal of Therapeutics (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Health Sciences › Health Professions › Pharmacy › Infant Health and Development
Keywords: irritable bowel syndrome, psychiatric comorbidity, mood disorders, anxiety disorders, schizophrenia, major depressive disorder, panic disorder, functional gastrointestinal disorders, prevalence, therapeutic implications
MeSH terms: Colonic Diseases, Functional, Depressive Disorder, Humans, Schizophrenia, United States, Comorbidity, Prevalence

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Comorbidity of irritable bowel syndrome in psychiatric patients: A review

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