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Comorbidity of Irritable Bowel Syndrome in Psychiatric Patients: A Review
Abstract
Irritable bowel syndrome (IBS), a functional gastrointestinal disorder, is present in 10% to 20% of the U.S. adult population. The syndrome is best defined as chronic abdominal discomfort with changes in stool frequency, consistency, and passage, with associated symptoms such as abdominal bloating or presence of mucus in stools. Several studies have shown that up to 70% to 90% of patients with IBS who seek treatment have psychiatric comorbidity, most notably mood and anxiety disorders. Recent studies have shown a high prevalence of IBS in psychiatric patients who seek treatment, with a prevalence of 19% in schizophrenia, 29% in major depression, and 46% in panic disorder among other disorders. Our article reviews the comorbidity of IBS in psychiatric patients and discusses implications for treatment.
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“There is a high prevalence of co-morbidity between psychiatric and gastrointestinal symptoms, e.g., 40–60% of patients with functional gastrointestinal disorders experience psychiatric symptoms [35] and up to 50% of psychiatric patients are diagnosed with irritable bowel syndrome [36], which clearly suggests broader implications of this axis on gastrointestinal and brain functions.”
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Metadata
- Authors
- Garakani, A., Win, T., Virk, S., Gupta, S., Kaplan, D., & Masand, P. S.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- Olean General Hospital (US)
- Corresponding author
- Masand, Prakash S.
- Venue
- American Journal of Therapeutics
- Published
- 2003-01
- Volume
- 10
- Issue
- 1
- Pages
- 61-67
- ISSN
- 1075-2765 (ISSN-L)
- OpenAlex
- W2041184383
- Cited by
- 149
- References
- 49
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 6 · 2023: 3 · 2022: 1 · 2021: 4 · 2020: 7 · 2019: 4 · 2018: 7 · 2017: 12 · 2016: 14 · 2015: 12 · 2014: 8 · 2013: 3 · 2012: 8
- FWCI
- 0.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Therapeutics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
- Keywords
- irritable bowel syndrome, psychiatric comorbidity, mood disorders, anxiety disorders, schizophrenia, major depressive disorder, panic disorder, functional gastrointestinal disorders, prevalence, therapeutic implications
- MeSH terms
- Colonic Diseases, Functional, Depressive Disorder, Humans, Schizophrenia, United States, Comorbidity, Prevalence
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