Oligodendrocytes and Ischemic Brain Injury

Dewar, Deborah; Underhill, Suzanne M.; Goldberg, Mark P.

doi:10.1097/01.wcb.0000053472.41007.f9

Cited by 335Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and TreatmentsNeurological Disorders and Treatments

Oligodendrocytes and Ischemic Brain Injury

Open access

Dewar, Deborah, Underhill, Suzanne M., Goldberg, Mark P.·2003·Journal of Cerebral Blood Flow & Metabolism

DOI 10.1097/01.wcb.0000053472.41007.f9

Open this paper in CoChat — free account Open PDF

Abstract

Oligodendrocytes, myelin-forming glial cells of the central nervous system, are vulnerable to damage in a variety of neurologic diseases. Much is known of primary myelin injury, which occurs in settings of genetic dysmyelination or demyelinating disease. There is growing awareness that oligodendrocytes are also targets of injury in acute ischemia. Recognition of oligodendrocyte damage in animal models of ischemia requires attention to their distinct histologic features or use of specific immunocytochemical markers. Like neurons, oligodendrocytes are highly sensitive to injury by oxidative stress, excitatory amino acids, trophic factor deprivation, and activation of apoptotic pathways. Understanding mechanisms of oligodendrocyte death may suggest new therapeutic strategies to preserve or restore white matter function and structure after ischemic insults.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1097/01.wcb.0000053472.41007.f9

Cites

123 of 123 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Oligodendrocytes express AMPA and kainate type glutamate receptors.
“Moreover, oligodendrocytes express AMPA and kainate type glutamate receptors, and are sensitive to excitotoxic damage from excess glutamate (Dewar et al, 2003;Matute et al, 1997;McDonald et al, 1998).”
From Neurocircuitry of Mood Disorders (2010) · cites this paper as Dewar et al, 2003
Oligodendrocytes are sensitive to excitotoxic damage from excess glutamate.
“Moreover, oligodendrocytes express AMPA and kainate type glutamate receptors, and are sensitive to excitotoxic damage from excess glutamate (Dewar et al, 2003;Matute et al, 1997;McDonald et al, 1998).”
From Neurocircuitry of Mood Disorders (2010) · cites this paper as Dewar et al, 2003
Oligodendrocytes express AMPA and kainate type glutamate receptors, and are sensitive to excitotoxic damage from excess glutamate.
“oligodendrocytes express AMPA and kainate type glutamate receptors, and are sensitive to excitotoxic damage from excess glutamate (Dewar et al. 2003; Matute et al. 1997; McDonald et al. 1998).”
From Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression (2008) · cites this paper as Dewar et al. 2003

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
Mccarthy, K., & de Vellis, J. (1980) · Journal of Cell Biology · doi:10.1083/jcb.85.3.890 · Cited by 3,915 · see citing works
Imaging Neuronal Subsets in Transgenic Mice Expressing Multiple Spectral Variants of GFP
Feng, G., Mellor, R. H., Bernstein, M., Keller-Peck, C., Nguyen, Q. T., Wallace, M., Nerbonne, J. M., Lichtman, J. W., & Sanes, J. R. (2000) · Neuron · doi:10.1016/s0896-6273(00)00084-2 · Cited by 3,042 · see citing works
A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium
RAFF, M. C., Miller, R. H., & Noble, M. (1983) · Nature · doi:10.1038/303390a0 · Cited by 2,030 · see citing works
Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System
Baumann, N., & Pham-Dinh, D. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.871 · Cited by 1,828 · see citing works
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia
Asahi, M., Wang, X., Mori, T., Sumii, T., Jung, J.-C., Moskowitz, M. A., Fini, M. E., & Lo, E. H. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-19-07724.2001 · Cited by 1,004 · see citing works
Neurobiology of Periventricular Leukomalacia in the Premature Infant
Volpe, J. J. (2001) · Pediatric Research · doi:10.1203/00006450-200111000-00003 · Cited by 945 · see citing works
Late Oligodendrocyte Progenitors Coincide with the Developmental Window of Vulnerability for Human Perinatal White Matter Injury
Back, S. A., Luo, N. L., Borenstein, N. S., Levine, J. M., Volpe, J. J., & Kinney, H. C. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-04-01302.2001 · Cited by 936 · see citing works
Inflammatory Mediators and Stroke: New Opportunities for Novel Therapeutics
Barone, F. C., & Feuerstein, G. (1999) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-199908000-00001 · Cited by 924 · see citing works
Glutamate excitotoxicity in a model of multiple sclerosis
Pitt, D., Werner, P., & Raine, C. S. (2000) · Nature Medicine · doi:10.1038/71555 · Cited by 855 · see citing works
Galactocerebroside is a specific cell-surface antigenic marker for oligodendrocytes in culture
RAFF, M. C., Mirsky, R., Fields, K. L., Lisak, R. P., Dorfman, S. H., Silberberg, D. H., Gregson, N. A., Leibowitz, S., & KENNEDY, M. C. (1978) · Nature · doi:10.1038/274813a0 · Cited by 808 · see citing works
Glial cell diversification in the rat optic nerve.
Raff, M. (1989) · Science · doi:10.1126/science.2648568 · Cited by 709 · see citing works
Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury
Goldberg, M. P., & Choi, D. W. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-08-03510.1993 · Cited by 693 · see citing works
Self-citation
Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons
Barres, B. A., & Raff, M. C. (1993) · Nature · doi:10.1038/361258a0 · Cited by 673 · see citing works
The oligodendrocyte precursor cell in health and disease
Levine, J. M., Reynolds, R., & Fawcett, J. W. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01691-x · Cited by 673 · see citing works
Cerebral White Matter Is Highly Vulnerable to Ischemia
Pantoni, L., García, J. H., & Gutierrez, J. A. (1996) · Stroke · doi:10.1161/01.str.27.9.1641 · Cited by 610 · see citing works
Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion
Back, S. A., Gan, X., Li, Y., Rosenberg, P. A., & Volpe, J. J. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-16-06241.1998 · Cited by 586 · see citing works
Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity
McDonald, J. W., Althomsons, S. P., Hyrc, K. L., Choi, D. W., & Goldberg, M. P. (1998) · Nature Medicine · doi:10.1038/nm0398-291 · Cited by 545 · see citing works
Self-citation
The Significance of Cerebral White Matter Abnormalities 100 Years After Binswanger’s Report
Pantoni, L., & García, J. H. (1995) · Stroke · doi:10.1161/01.str.26.7.1293 · Cited by 536 · see citing works
Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention
Oka, A., Belliveau, M. J., Rosenberg, P. A., & Volpe, J. J. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-04-01441.1993 · Cited by 504 · see citing works
Autoimmune encephalomyelitis ameliorated by AMPA antagonists
Smith, T., Groom, A., Zhu, B., & Turski, L. (2000) · Nature Medicine · doi:10.1038/71548 · Cited by 467 · see citing works
Low Glutathione and High Iron Govern the Susceptibility of Oligodendroglial Precursors to Oxidative Stress
Thorburne, S. K., & Juurlink, B. H. J. (1996) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1996.67031014.x · Cited by 390 · see citing works
NBQX Attenuates Excitotoxic Injury in Developing White Matter
Follett, P. L., Rosenberg, P. A., Volpe, J. J., & Jensen, F. E. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-24-09235.2000 · Cited by 389 · see citing works
Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes.
LoPresti, P., Szuchet, S., Papasozomenos, S. C., Zinkowski, R. P., & Binder, L. I. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.22.10369 · Cited by 388 · see citing works
Control of oligodendrocyte number in the developing rat optic nerve
Barres, B. A., & RAFF, M. C. (1994) · Neuron · doi:10.1016/0896-6273(94)90305-0 · Cited by 385 · see citing works
Ion Channels In Vertebrate Glia
Barres, B. A. (1990) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.13.1.441 · Cited by 373 · see citing works
Ion Channels in Vertebrate Glia
Barres, B. A., Chun, L. L. Y., & Corey, D. P. (1990) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.13.030190.002301 · Cited by 355 · see citing works
Glutamate receptor-mediated toxicity in optic nerve oligodendrocytes
Matute, C., Sánchez-Gómez, M. V., Martínez-Millán, L., & Miledi, R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.16.8830 · Cited by 352 · see citing works
VARIATION WITH AGE IN THE VOLUMES OF GREY AND WHITE MATTER IN THE CEREBRAL HEMISPHERES OF MAN: MEASUREMENTS WITH AN IMAGE ANALYSER
MILLER, A. K. H., Alston, R. L., & Corsellis, J. (1980) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1980.tb00283.x · Cited by 351 · see citing works
MAPs, MARKs and microtubule dynamics
Drewes, G., Ebneth, A., & Mandelkow, E. (1998) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(98)01245-6 · Cited by 346 · see citing works
The link between excitotoxic oligodendroglial death and demyelinating diseases
Matute, C., Alberdi, E. M., Domercq, M., Pérez‐Cerdá, F., Pérez‐Samartín, A., & Sánchez‐Gómez, M. V. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01746-x · Cited by 346 · see citing works
Purified astrocytes promote the in vitro division of a bipotential glial progenitor cell.
Noble, M., & Murray, K. (1984) · The EMBO Journal · doi:10.1002/j.1460-2075.1984.tb02122.x · Cited by 334 · see citing works
Rapid Ischemic Cell Death in Immature Oligodendrocytes: A Fatal Glutamate Release Feedback Loop
Fern, R. F., & Möller, T. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-01-00034.2000 · Cited by 321 · see citing works
Hydrated autoclave pretreatment enhances tau immunoreactivity in formalin-fixed normal and Alzheimer's disease brain tissues.
Shin, R., Iwaki, T., Kitamoto, T., & Tateishi, J. (1991) · PubMed · Cited by 318 · see citing works
Glial cells of the oligodendrocyte lineage express both kainate- and AMPA-preferring subtypes of glutamate receptor
Patneau, D. K., Wright, P. W., Winters, C. A., Mayer, M. L., & Gallo, V. (1994) · Neuron · doi:10.1016/0896-6273(94)90277-1 · Cited by 314 · see citing works
Clinical features of subcortical arteriosclerotic encephalopathy (Binswanger disease)
Caplan, L. R., & Schoene, W. C. (1978) · Neurology · doi:10.1212/wnl.28.12.1206 · Cited by 283 · see citing works
Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats
Mabuchi, T., Kitagawa, K., Ohtsuki, T., Kuwabara, K., Yagita, Y., Yanagihara, T., Hori, M., & Matsumoto, M. (2000) · Stroke · doi:10.1161/01.str.31.7.1735 · Cited by 280 · see citing works
BDNF Blocks Caspase-3 Activation in Neonatal Hypoxia–Ischemia
Han, B. H., D'Costa, A. P., Back, S. A., Parsadanian, M., Patel, S., Shah, A. R., Gidday, J. M., Srinivasan, A. N., Deshmukh, M., & Holtzman, D. M. (2000) · Neurobiology of Disease · doi:10.1006/nbdi.1999.0275 · Cited by 267 · see citing works
Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat
Irving, E. A., Barone, F. C., Reith, A. D., Hadingham, S. J., & Parsons, A. A. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00043-7 · Cited by 266 · see citing works
AMPA/Kainate Receptor Activation Mediates Hypoxic Oligodendrocyte Death and Axonal Injury in Cerebral White Matter
Tekkök, S. B., & Goldberg, M. P. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-12-04237.2001 · Cited by 256 · see citing works
Self-citation
Novel Injury Mechanism in Anoxia and Trauma of Spinal Cord White Matter: Glutamate Release via Reverse Na+-dependent Glutamate Transport
Li, S., Mealing, G. A. R., Morley, P., & Stys, P. K. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-14-j0002.1999 · Cited by 252 · see citing works
In situ demonstration of mature oligodendrocytes and their processes: An immunocytochemical study with a new monoclonal antibody, Rip
Friedman, B., Hockfield, S. J., Black, J. A., Woodruff, K., & Waxman, S. G. (1989) · Glia · doi:10.1002/glia.440020510 · Cited by 248 · see citing works
Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX
Wrathall, J., Choiniere, D., & Teng, Y. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-11-06598.1994 · Cited by 235 · see citing works
Role of NMDA and Non-NMDA Ionotropic Glutamate Receptors in Traumatic Spinal Cord Axonal Injury
Agrawal, S. K., & Fehlings, M. G. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-03-01055.1997 · Cited by 226 · see citing works
Selective Glial Vulnerability following Transient Global Ischemia in Rat Brain
Petito, C. K., Olarte, J.-P., Roberts, B., Nowak, T. S., & Pulsinell, W. A. (1998) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199803000-00004 · Cited by 205 · see citing works
Oligodendrocyte lineage and the motor neuron connection
Richardson, W. D., Smith, H., Sun, T., Pringle, N., Hall, A., & Woodruff, R. (2000) · Glia · doi:10.1002/(sici)1098-1136(20000115)29:2 · Cited by 198 · see citing works
Arrested Oligodendrocyte Lineage Progression During Human Cerebral White Matter Development: Dissociation Between the Timing of Progenitor Differentiation and Myelinogenesis
Back, S. A., Luo, N. L., Borenstein, N. S., Volpe, J. J., & Kinney, H. C. (2002) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/61.2.197 · Cited by 196 · see citing works
Light and electron microscopic localization of a cell surface antigen (NG2) in the rat cerebellum: association with smooth protoplasmic astrocytes
Levine, J., & Card, J. P. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-09-02711.1987 · Cited by 191 · see citing works
Demyelination and remyelination after acute spinal cord compression
Gledhill, R. F., Harrison, B. M., & McDonald, W. I. (1973) · Experimental Neurology · doi:10.1016/0014-4886(73)90169-6 · Cited by 181 · see citing works
Ebselen Protects Both Gray and White Matter in a Rodent Model of Focal Cerebral Ischemia
Imai, H., Masayasu, H., Dewar, D., Graham, D. I., & Macrae, I. M. (2001) · Stroke · doi:10.1161/hs0901.095725 · Cited by 177 · see citing works
Self-citation
The NG2 chondroitin sulfate proteoglycan: a multifunctional proteoglycan associated with immature cells.
Levine, J., & Nishiyama, A. (1996) · PubMed · Cited by 171 · see citing works
Amelioration of Functional Deficits from Spinal Cord Trauma with Systemically Administered NBQX, an Antagonist of Non-N-methyl-D-aspartate receptors
Wrathall, J. R., Teng, Y. D., & Choiniere, D. (1996) · Experimental Neurology · doi:10.1006/exnr.1996.0012 · Cited by 153 · see citing works
Increased Expression of IL-1β Converting Enzyme in Hippocampus after Ischemia: Selective Localization in Microglia
Bhat, R. V., DiRocco, R. J., Marcy, V. R., Flood, D. G., Zhu, Y. X., Dobrzański, P., Siman, R., Scott, R., Contreras, P. C., & Miller, M. S. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-13-04146.1996 · Cited by 152 · see citing works
Oligodendrocyte origins.
Miller, R. H. (1996) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)80036-1 · Cited by 152 · see citing works
AMPA and Kainate Receptors Each Mediate Excitotoxicity in Oligodendroglial Cultures
Sánchez‐Gómez, M. V., & Matute, C. (1999) · Neurobiology of Disease · doi:10.1006/nbdi.1999.0264 · Cited by 150 · see citing works
Activation of glutamate receptors and glutamate uptake in identified macroglial cells in rat cerebellar cultures.
Wyllie, D. J. A., Mathie, A. A., Symonds, C. J., & Cull-Candy, S. G. (1991) · The Journal of Physiology · doi:10.1113/jphysiol.1991.sp018383 · Cited by 148 · see citing works
Rat oligodendrocytes express the vitamin D3 receptor and respond to 1,25-dihydroxyvitamin D3
Baas, D., Pr�fer, K., Ittel, M. E., Kuchler‐Bopp, S., Labourdette, G., Sarli�ve, L. L., & Brachet, P. (2000) · Glia · doi:10.1002/(sici)1098-1136(200007)31:1 · Cited by 146 · see citing works
Acquired perinatal leukoencephalopathy
Leviton, A. E., & Gilles, F. H. (1984) · Annals of Neurology · doi:10.1002/ana.410160102 · Cited by 140 · see citing works
Cellular events during partial cerebral ischemia
García, J. H., Kalimo, H., Kamijyo, Y., & Trump, B. F. (1977) · Virchows Archiv B Cell Pathology Including Molecular Pathology · doi:10.1007/bf02889433 · Cited by 135 · see citing works
Oligodendrocytes and Microglia Are Selectively Vulnerable to Combined Hypoxia and Hypoglycemia Injury in Vitro
Lyons, S. A., & Kettenmann, H. (1998) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-199805000-00007 · Cited by 134 · see citing works
α‐Amino‐3‐Hydroxy‐5‐Methyl‐4‐Isoxazolepropionate (AMPA) Receptors Mediate Excitotoxicity in the Oligodendroglial Lineage
Yoshioka, A., Hardy, M., Younkin, D. P., Grinspan, J. B., Stern, J. L., & Pleasure, D. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.64062442.x · Cited by 134 · see citing works
Perinatal Hypoxia-Ischemia Induces Apoptotic and Excitotoxic Death of Periventricular White Matter Oligodendrocyte Progenitors
Ness, J. K., Romanko, M. J., Rothstein, R. P., Wood, T. L., & Levison, S. W. (2001) · Developmental Neuroscience · doi:10.1159/000046144 · Cited by 131 · see citing works
Even in culture, oligodendrocytes myelinate solely axons.
Lubetzki, C., Demerens, C., Anglade, P., Villarroya, H., Frankfurter, A. J., Lee, V. M., & Zalc, B. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.14.6820 · Cited by 129 · see citing works
Oligodendroglial precursor cell susceptibility to hypoxia is related to poor ability to cope with reactive oxygen species
Husain, J., & Juurlink, B. H. J. (1995) · Brain Research · doi:10.1016/0006-8993(95)00832-b · Cited by 127 · see citing works
Expression of microtubule-associated proteins MAP2 and tau in cultured rat brain oligodendrocytes
Müller, R., Heinrich, M., Heck, S., Blohm, D., & Richter-Landsberg, C. (1997) · Cell and Tissue Research · doi:10.1007/s004410050809 · Cited by 127 · see citing works
Demonstration of a specific localization of carbonic anhydrase C in the glial cells of rat CNS by an immunohistochemical method
Roussel, G., Delaunoy, J., Nussbaum, J. L., & Mandel, P. (1979) · Brain Research · doi:10.1016/0006-8993(79)90599-7 · Cited by 126 · see citing works
A Pi Form of Glutathione‐S‐Transferase Is a Myelin‐and Oligodendrocyte‐Associated Enzyme in Mouse Brain
Tansey, F. A., & Cammer, W. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb02104.x · Cited by 120 · see citing works
Perinatal telencephalic leucoencephalopathy.
Gilles, F. H., & Murphy, S. F. (1969) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.32.5.404 · Cited by 120 · see citing works
Important Role of Reverse Na+-Ca2+Exchange in Spinal Cord White Matter Injury at Physiological Temperature
Li, S., Jiang, Q., & Stys, P. K. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.84.2.1116 · Cited by 120 · see citing works
Ischemic damage and subsequent proliferation of oligodendrocytes in focal cerebral ischemia
Mandai, K., Matsumoto, M., Kitagawa, K., Matsushita, K., Ohtsuki, T., Mabuchi, T., Colman, D., Kamada, T., & Yanagihara, T. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00517-9 · Cited by 118 · see citing works
Tau Dephosphorylation at Tau-1 Site Correlates with its Association to Cell Membrane
Arrasate, M., Pérez, M., & Ávila, J. (2000) · Neurochemical Research · doi:10.1023/a:1007583214722 · Cited by 116 · see citing works
The Behavioral Neurology of White Matter
Filley, C. M. (2012) · Oxford University Press eBooks · doi:10.1093/med/9780199743261.003.020 · Cited by 113 · see citing works
Effects of the Sodium Channel Blocker Tetrodotoxin on Acute White Matter Pathology After Experimental Contusive Spinal Cord Injury
Rosenberg, L., Teng, Y. D., & Wrathall, J. R. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-14-06122.1999 · Cited by 112 · see citing works
Mechanisms of damage to myelin and oligodendrocytes and their relevance to disease
Merrill, & Scolding, N. J. (1999) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.1999.00200.x · Cited by 111 · see citing works
Light and electron microscope localization of the microtubule- associated tau protein in rat brain
Migheli, A., Butler, M., Brown, K., & Shelanski, M. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-06-01846.1988 · Cited by 109 · see citing works
Delayed Antagonism of AMPA/Kainate Receptors Reduces Long-Term Functional Deficits Resulting from Spinal Cord Trauma
Wrathall, J. R., Teng, Y. D., & Marriott, R. (1997) · Experimental Neurology · doi:10.1006/exnr.1997.6506 · Cited by 108 · see citing works
Nerve fibres in spinal cord impact injuries
Griffiths, I. R., & McCulloch, M. C. (1983) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(83)90093-x · Cited by 106 · see citing works
Oxygen-Glucose Deprivation Induces Inducible Nitric Oxide Synthase and Nitrotyrosine Expression in Cerebral Endothelial Cells
Xu, J., He, L., Ahmed, S. H., Chen, S.-W., Goldberg, M. P., Beckman, J. S., & Hsu, C. Y. (2000) · Stroke · doi:10.1161/01.str.31.7.1744 · Cited by 106 · see citing works
Self-citation
Glutamate regulates intracellular calcium and gene expression in oligodendrocyte progenitors through the activation of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.
Pende, M., Holtzclaw, L. A., Curtis, J. L., Russell, J. T., & Gallo, V. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.8.3215 · Cited by 104 · see citing works
Excitatory amino acid receptors in glia: Different subtypes for distinct functions?
Gallo, V., & Russell, J. T. (1995) · Journal of Neuroscience Research · doi:10.1002/jnr.490420102 · Cited by 104 · see citing works
Rapid Alteration of Tau in Oligodendrocytes After Focal Ischemic Injury in the Rat: Involvement of Free Radicals
Irving, E. A., Yatsushiro, K., McCulloch, J., & Dewar, D. (1997) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-199706000-00003 · Cited by 103 · see citing works
Self-citation
Oligodendroglial cell death induced by oxygen radicals and its protection by catalase
Kim, Y. S., & Kim, S. U. (1991) · Journal of Neuroscience Research · doi:10.1002/jnr.490290111 · Cited by 99 · see citing works
Focal cerebral ischemia induces increased myelin basic protein and growth-associated protein-43 gene transcription in peri-infarct areas in the rat brain
Gregersen, R., Christensen, T., Lehrmann, E., Diemer, N. H., & Finsen, B. R. (2001) · Experimental Brain Research · doi:10.1007/s002210100715 · Cited by 97 · see citing works
The Behavioral Neurology Of White Matter
Filley, C. M. (2001) · doi:10.1093/oso/9780195135619.001.0001 · Cited by 97 · see citing works
Glutamate receptor agonists stimulate diverse calcium responses in different types of cultured rat cortical glial cells
Holzwarth, J., Gibbons, S. J., Brorson, J., Philipson, L. H., & Miller, R. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-04-01879.1994 · Cited by 96 · see citing works
Ampa/kainate receptor activation in murine oligodendrocyte precursor cells leads to activation of a cation conductance, calcium influx and blockade of delayed rectifying K+ channels
Borges, K., Ohlemeyer, C., Trotter, J., & Kettenmann, H. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90012-4 · Cited by 96 · see citing works
Caspases determine the vulnerability of oligodendrocytes in the ischemic brain
Shibata, M., Hisahara, S., Hara, H., Yamawaki, T., Fukuuchi, Y., Yuan, J., Okano, H., & Miura, M. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10203 · Cited by 95 · see citing works
White Matter Injury in Spinal Cord Ischemia
Kanellopoulos, G. K., Xu, X., Hsu, C. Y., Lu, X., Sundt, T. M., & Kouchoukos, N. T. (2000) · Stroke · doi:10.1161/01.str.31.8.1945 · Cited by 93 · see citing works
Insulin-like Growth Factor I, but Not Neurotrophin-3, Sustains Akt Activation and Provides Long-Term Protection of Immature Oligodendrocytes from Glutamate-Mediated Apoptosis
Ness, J. P. (2002) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2002.1149 · Cited by 91 · see citing works
Oligodendroglial lineage cells express neuroligand receptors
Kastritsis, C. H., & McCarthy, K. D. (1993) · Glia · doi:10.1002/glia.440080206 · Cited by 88 · see citing works
Tau protein is altered by focal cerebral ischaemia in the rat: an immunohistochemical and immunoblotting study
Dewar, D., & Dawson, D. A. (1995) · Brain Research · doi:10.1016/0006-8993(95)00417-o · Cited by 88 · see citing works
Self-citation
Cell death and plasticity after experimental spinal cord injury
Beattie, M. S., Li, Q., & Bresnahan, J. C. (2000) · Progress in brain research · doi:10.1016/s0079-6123(00)28003-5 · Cited by 84 · see citing works
AMPA receptor‐mediated toxicity in oligodendrocyte progenitors involves free radical generation and activation of JNK, calpain and caspase 3
Liu, H., Giasson, B. I., Mushynski, W. E., & Almazán, G. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.00981.x · Cited by 82 · see citing works
Activation of NG2-positive oligodendrocyte progenitor cells during post-ischemic reperfusion in the rat brain
Tanaka, K., Nogawa, S., Ito, D., Suzuki, S., Dembo, T., Kosakai, A., & Fukuuchi, Y. (2001) · Neuroreport · doi:10.1097/00001756-200107200-00025 · Cited by 80 · see citing works
Immunoreactivity of Cyclin D1/cdk4 in Neurons and Oligodendrocytes After Focal Cerebral Ischemia in Rat
Li, Y., Chopp, M., Powers, C., & Jiang, N. (1997) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-199708000-00003 · Cited by 75 · see citing works
Assessment of white matter injury following prolonged focal cerebral ischaemia in the rat
Irving, E. A., Bentley, D., & Parsons, A. A. (2001) · Acta Neuropathologica · doi:10.1007/s004010100416 · Cited by 75 · see citing works
Lineage, migration, and fate determination of postnatal subventricular zone cells in the mammalian CNS
Goldman, J. E. (1995) · Journal of Neuro-Oncology · doi:10.1007/bf01052660 · Cited by 74 · see citing works
Oligodendroglial development in human fetal cerebrum
Rivkin, M. J., Flax, J. D., Mozell, R. L., Osathanondh, R., Volpe, J. J., & Villa‐Komaroff, L. (1995) · Annals of Neurology · doi:10.1002/ana.410380116 · Cited by 69 · see citing works
Increased tau immunoreactivity in oligodendrocytes following human stroke and head injury
Irving, E. A., Nicoll, J. A. R., Graham, D. I., & Dewar, D. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(96)12856-1 · Cited by 68 · see citing works
Self-citation
Characterization and sleep deprivation-induced expression modulation of dendrin, a novel dendritic protein in rat brain neurons
Neuner‐Jehle, M., Denizot, J., Borb�ly, A. A., & Mallet, J. J. (1996) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19961015)46:2 · Cited by 68 · see citing works
Glutamate Induces c‐fos Proto‐oncogene Expression and Inhibits Proliferation in Oligodendrocyte Progenitors: Receptor Characterization
Liu, H., & Almazán, G. (1995) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1995.tb01032.x · Cited by 66 · see citing works
Microglia/Macrophages Proliferate in Striatum and Neocortex but Not in Hippocampus after Brief Global Ischemia That Produces Ischemic Tolerance in Gerbil Brain
Liu, J., Bartels, M. N., Lu, A., & Sharp, F. R. (2001) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200104000-00005 · Cited by 63 · see citing works
Mouse resident microglia: Isolation and characterization of immunoregulatory properties with naïve CD4+and CD8+T‐cells
Havenith, C. E. G., Askew, D., & Walker, W. S. G. (1998) · Glia · doi:10.1002/(sici)1098-1136(199804)22:4 · Cited by 62 · see citing works
Quantitative Assessment of Ischemic Pathology in Axons, Oligodendrocytes, and Neurons: Attenuation of Damage after Transient Ischemia
Valeriani, V., Dewar, D., & McCulloch, J. (2000) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200005000-00002 · Cited by 60 · see citing works
Self-citation
Grey Matter and White Matter Ischemic Damage is Reduced by the Competitive AMPA Receptor Antagonist, SPD 502
McCracken, E., Fowler, J. H., Dewar, D., Morrison, S., & McCulloch, J. (2002) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200209000-00006 · Cited by 57 · see citing works
Self-citation
Cyanide intoxication in Macaca mulatta
Brierley, J. B., Prior, P. F., Calverley, J., & Brown, A. W. (1977) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(77)90011-9 · Cited by 57 · see citing works
Non-N-methyl-d-aspartate glutamate receptors mediate oxygen–glucose deprivation-induced oligodendroglial injury
Yoshioka, A., Yamaya, Y., Saiki, S., Kanemoto, M., Hirose, G., Beesley, J., & Pleasure, D. (2000) · Brain Research · doi:10.1016/s0006-8993(99)02359-8 · Cited by 55 · see citing works
Transformation of Postischemic Perineuronal Glial Cells. I. Electron Microscopic Studies
Petito, C. K. (1986) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1986.109 · Cited by 52 · see citing works
Early and Late Neuropathological Changes in Perinatal White Matter Damage
Dambska, M., Laure‐Kamionowska, M., & Schmidt-Sidor, B. (1989) · Journal of Child Neurology · doi:10.1177/088307388900400408 · Cited by 52 · see citing works
SPD 502: A Water-Soluble and In Vivo Long-Lasting Ampa Antagonist with Neuroprotective Activity
Nielsen, E. Ø., Varming, T., Mathiesen, C., Jensen, L. H., Møller, A., Gouliaev, A. H., Wätjen, F., & Drejer, J. (1999) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38297-7 · Cited by 52 · see citing works
GAL4/UAS-WGA system as a powerful tool for tracingDrosophila transsynaptic neural pathways
Tabuchi, K., Sawamoto, K., Suzuki, E., Ozaki, K., Sone, M., Hama, C., Morimoto-Tanifuji, T., Yuasa, Y., Yoshihara, Y., Nose, A., et al. (2000) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(20000101)59:1 · Cited by 51 · see citing works
Analysis of Fractal Dimension of O2A Glial Cells Differentiating in Vitro
Behar, T. N. (2001) · Methods · doi:10.1006/meth.2001.1203 · Cited by 49 · see citing works
THE FUNCTION OF PERINEURONAL SATELLITE OLIGODENDROCYTES: AN IMMUNOHISTOCHEMICAL STUDY
Ludwin, S. K. (1984) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1984.tb00345.x · Cited by 47 · see citing works
Temporal Profiles of the Subcellular Localization of Bim, a BH3-Only Protein, during Middle Cerebral Artery Occlusion in Mice
Shibata, M., Hattori, H., Sasaki, T., Gotoh, J., Hamada, J., & Fukuuchi, Y. (2002) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200207000-00006 · Cited by 36 · see citing works
Group I metabotropic glutamate receptors limit AMPA receptor-mediated oligodendrocyte progenitor cell death
Kelland, E. E., & Toms, N. J. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01157-8 · Cited by 35 · see citing works
Retinoic acid potentiated the protective effect of NGF against staurosporine-induced apoptosis in cultured chick neurons by increasing the trkA protein expression
Ahlemeyer, B., H�hne, R., & Krieglstein, J. (2000) · Journal of Neuroscience Research · doi:10.1002/1097-4547(20000615)60:6 · Cited by 34 · see citing works
Expression and regulation of kainate and AMPA receptors in uncommitted and committed neural progenitors
Gallo, V., Pende, M., Scherer, S., Molné, M., & Wright, P. K. (1995) · Neurochemical Research · doi:10.1007/bf01694536 · Cited by 33 · see citing works
Intracortical perfusion of glutamate in vivo induces alterations of tau and microtubule-associated protein 2 immunoreactivity in the rat
Irving, E. A., McCulloch, J., & Dewar, D. (1996) · Acta Neuropathologica · doi:10.1007/s004010050507 · Cited by 31 · see citing works
Self-citation
Phosphorylation of Cyclic Adenosine Monophosphate Response Element Binding Protein in Oligodendrocytes in the Corpus Callosum after Focal Cerebral Ischemia in the Rat
Tanaka, K., Nogawa, S., Ito, D., Suzuki, S., Dembo, T., Kosakai, A., & Fukuuchi, Y. (2001) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200110000-00006 · Cited by 25 · see citing works
Appearance of tau-2 immunoreactivity in glial cells in human brain with cerebral infarction
Uchihara, T., Tsuchiya, K., Nakamura, A., & Ikeda, K. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01103-4 · Cited by 24 · see citing works
Hydrogen peroxide induces transient dephosphorylation of tau protein in cultured rat oligodendrocytes
LoPresti, P., & Konat, G. W. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)02137-1 · Cited by 19 · see citing works
Morphologic correlates of age at death of infants with perinatal telencephalic leukoencephalopathy.
Leviton, A. E., & Gilles, F. H. (1971) · PubMed · Cited by 17 · see citing works
Cellular mechanisms of white matter ischemia: what can we learn from culture models?
Underhill, S. M., Tekkök, S. B., Hasbani, M. J., & Goldberg, M. P. (2002) · Cambridge University Press eBooks · doi:10.1017/cbo9780511544910.010 · Cited by 2 · see citing works
Self-citation
Untitled work
Webster (1996) · doi:10.1002/(sici)1097-4547(19961001)46:1

Flagged first, then by citations

Research works printed but not linked: 1

[105]105. Szuchet S (1995) The morphology and ultrastructure of oligodendro- cytes and their functional implications. In: Neuroglia (Kettnemann H, Ransom BR, eds), New York, NY: Oxford University Press, 23-43

Sorted by citations

Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression
Drevets, W. C., Price, J. L., & Furey, M. L. (2008) · Brain Structure and Function · doi:10.1007/s00429-008-0189-x · Cited by 2,209 · see citing works
“Moreover, oligodendrocytes express AMPA and kainate type glutamate receptors, and are sensitive to excitotoxic damage from excess glutamate (Dewar et al. 2003; Matute et al. 1997; McDonald et al. 1998).”
Background
Ischaemic stroke
Campbell, B. C. V., Silva, D. A. D., Macleod, M. R., Coutts, S. B., Schwamm, L. H., Davis, S. M., & Donnan, G. A. (2019) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0118-8 · Cited by 1,858 · see citing works
Neurocircuitry of Mood Disorders
Price, J. L., & Drevets, W. C. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.104 · Cited by 1,606 · see citing works
Differential aging of the brain: Patterns, cognitive correlates and modifiers
Raz, N., & Rodrigue, K. M. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2006.07.001 · Cited by 1,195 · see citing works
Neuroprotection for ischemic stroke: Past, present and future
Ginsberg, M. D. (2008) · Neuropharmacology · doi:10.1016/j.neuropharm.2007.12.007 · Cited by 779 · see citing works
NMDA receptors are expressed in oligodendrocytes and activated in ischaemia
Káradóttir, R. T., Cavelier, P., Bergersen, L. H., & Attwell, D. (2005) · Nature · doi:10.1038/nature04302 · Cited by 773 · see citing works
The biphasic function of microglia in ischemic stroke
Ma, Y., Wang, J., Wang, Y., & Yang, G. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.01.005 · Cited by 724 · see citing works
Pathophysiology of Cerebral Ischemia and Brain Trauma: Similarities and Differences
Bramlett, H., & Dietrich, W. (2004) · Journal of Cerebral Blood Flow and Metabolism · doi:10.1097/01.wcb.0000111614.19196.04 · Cited by 622 · see citing works
NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury
Salter, M. G., & Fern, R. F. (2005) · Nature · doi:10.1038/nature04301 · Cited by 556 · see citing works
The life, death, and replacement of oligodendrocytes in the adult CNS
McTigue, D. M., & Tripathi, R. B. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05570.x · Cited by 455 · see citing works
Cellular and molecular neuropathology of the cuprizone mouse model: Clinical relevance for multiple sclerosis
Praet, J., Guglielmetti, C., Berneman, Z., Van der Linden, A., & Ponsaerts, P. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.10.004 · Cited by 435 · see citing works
Autophagy in ischemic stroke
Wang, P., Shao, B., Deng, Z., Chen, S., Yue, Z., & Miao, C. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.01.001 · Cited by 396 · see citing works
Glial reduction in amygdala in major depressive disorder is due to oligodendrocytes
Hamidi, M., Drevets, W. C., & Price, J. L. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.11.006 · Cited by 369 · see citing works
RETRACTED ARTICLE: Pericyte degeneration causes white matter dysfunction in the mouse central nervous system
Montagne, A., Nikolakopoulou, A. M., Zhao, Z., Sagare, A. P., Si, G., Lazic, D., Barnes, S. R., Daianu, M., Ramanathan, A., Go, A., et al. (2018) · Nature Medicine · doi:10.1038/nm.4482 · Cited by 344 · see citing works
Retracted
Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury
Starkov, A. A., Chinopoulos, C., & Fiskum, G. M. (2004) · Cell Calcium · doi:10.1016/j.ceca.2004.02.012 · Cited by 339 · see citing works
Glutamate‐mediated glial injury: Mechanisms and clinical importance
Matute, C., Domercq, M., & Sánchez‐Gómez, M. V. (2005) · Glia · doi:10.1002/glia.20275 · Cited by 330 · see citing works
General mechanisms of axonal damage and its prevention
Stys, P. K. (2005) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2005.03.031 · Cited by 314 · see citing works
Functional differences between microglia and monocytes after ischemic stroke
Ritzel, R. M., Patel, A. R., Grenier, J. M., Crapser, J., Verma, R., Jellison, E. R., & McCullough, L. D. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0329-1 · Cited by 295 · see citing works
The neurobiology of depression in later-life: Clinical, neuropsychological, neuroimaging and pathophysiological features
Naismith, S. L., Norrie, L. M., Mowszowski, L., & Hickie, I. B. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.05.009 · Cited by 269 · see citing works
Excitotoxic damage to white matter
Matute, C., Alberdi, E. M., Domercq, M., Sánchez‐Gómez, M. V., Pérez‐Samartín, A., Antigüedad, A. R., & Pérez‐Cerdá, F. (2007) · Journal of Anatomy · doi:10.1111/j.1469-7580.2007.00733.x · Cited by 259 · see citing works
Neurotransmitter receptors in the life and death of oligodendrocytes
Káradóttir, R. T., & Attwell, D. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.070 · Cited by 252 · see citing works
The phenotypic spectrum of organic acidurias and urea cycle disorders. Part 2: the evolving clinical phenotype
Kölker, S., Valayannopoulos, V., Burlina, A., Sykut‐Cegielska, J., Wijburg, F. A., Teles, E. L., Zeman, J., Dionisi‐Vici, C., Barić, I., Karall, D., et al. (2015) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-015-9840-x · Cited by 235 · see citing works
Roles of zinc and metallothionein-3 in oxidative stress-induced lysosomal dysfunction, cell death, and autophagy in neurons and astrocytes
Lee, S.-J., & Koh, J. (2010) · Molecular Brain · doi:10.1186/1756-6606-3-30 · Cited by 217 · see citing works
Neuroprotective Role of Haptoglobin after Intracerebral Hemorrhage
Zhao, X., Shen, S., Sun, G., Strong, R., Zhang, J., Grotta, J. C., & Aronowski, J. A. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3776-09.2009 · Cited by 170 · see citing works
Molecular regulation of neuroinflammation in glaucoma: Current knowledge and the ongoing search for new treatment targets
Tezel, G. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2021.100998 · Cited by 172 · see citing works
Oxidative Stress Interferes With White Matter Renewal After Prolonged Cerebral Hypoperfusion in Mice
Miyamoto, N., Maki, T., Pham, L. D., Hayakawa, K., Seo, J. H., Mandeville, E. T., Mandeville, J. B., Kim, K., Lo, E. H., & Arai, K. (2013) · Stroke · doi:10.1161/strokeaha.113.002813 · Cited by 157 · see citing works
Rosiglitazone Promotes White Matter Integrity and Long-Term Functional Recovery After Focal Cerebral Ischemia
Han, L., Cai, W., Mao, L., Liu, J., Li, P., Leak, R. K., Xu, Y., Hu, X., & Chen, J. (2015) · Stroke · doi:10.1161/strokeaha.115.010091 · Cited by 155 · see citing works
The interleukin-4/PPARγ signaling axis promotes oligodendrocyte differentiation and remyelination after brain injury
Zhang, Q., Zhu, W., Xu, F., Dai, X., Shi, L., Cai, W., Mu, H., Hitchens, T. K., Foley, L. M., Liu, X., et al. (2019) · PLOS Biology · doi:10.1371/journal.pbio.3000330 · Cited by 160 · see citing works
Cilostazol Protects Against Brain White Matter Damage and Cognitive Impairment in a Rat Model of Chronic Cerebral Hypoperfusion
Watanabe, T., Zhang, N., Liu, M., Tanaka, R., Mizuno, Y., & Urabe, T. (2006) · Stroke · doi:10.1161/01.str.0000221783.08037.a9 · Cited by 149 · see citing works
Oligodendrogenesis after cerebral ischemia
Zhang, R., Chopp, M., & Zhang, Z. G. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00201 · Cited by 149 · see citing works
Accelerated infarct development, cytogenesis and apoptosis following transient cerebral ischemia in aged rats
Popa‐Wagner, A., Badan, I., Walker, L. C., Groppa, S., Pătrană, N., & Kessler, C. (2006) · Acta Neuropathologica · doi:10.1007/s00401-006-0164-7 · Cited by 136 · see citing works
Oligodendroglial abnormalities in schizophrenia, mood disorders and substance abuse. Comorbidity, shared traits, or molecular phenocopies?
Sokolov, B. P. (2007) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145706007322 · Cited by 124 · see citing works
Hypoxia-Induced Neuroinflammatory White-Matter Injury Reduced by Minocycline in SHR/SP
Jalal, F. Y., Yang, Y. R., Thompson, J. F., Roitbak, T., & Rosenberg, G. A. (2015) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2015.21 · Cited by 121 · see citing works
Single-cell and spatial atlases of spinal cord injury in the Tabulae Paralytica
Skinnider, M. A., Gautier, M., Teo, A. Y. Y., Kathe, C., Hutson, T. H., Laskaratos, A., de Coucy, A., Regazzi, N., Aureli, V., James, N. D., et al. (2024) · Nature · doi:10.1038/s41586-024-07504-y · Cited by 131 · see citing works
Brain vulnerability and viability after ischaemia
Daniele, S. G., Trummer, G., Hossmann, K. A., Vrselja, Z., Benk, C., Gobeske, K. T., Damjanović, D., Andrijević, D., Pooth, J., Dellal, D., et al. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00488-y · Cited by 118 · see citing works
The immunomodulatory oligodendrocyte
Zeis, T., Enz, L., & Schaeren-Wiemers, N. (2016) · Brain Research · doi:10.1016/j.brainres.2015.09.021 · Cited by 120 · see citing works
Oxidative injury triggers autophagy in astrocytes: The role of endogenous zinc
Lee, S., Cho, K. S., & Koh, J. (2009) · Glia · doi:10.1002/glia.20854 · Cited by 115 · see citing works
From demyelination to remyelination: The road toward therapies for spinal cord injury
Papastefanaki, F., & Matsas, R. (2015) · Glia · doi:10.1002/glia.22809 · Cited by 113 · see citing works
Upregulation of oligodendrocyte progenitor cells associated with restoration of mature oligodendrocytes and myelination in peri-infarct area in the rat brain
Tanaka, K., Nogawa, S., Suzuki, S., Dembo, T., & Kosakai, A. (2003) · Brain Research · doi:10.1016/s0006-8993(03)03317-1 · Cited by 113 · see citing works
Valproic acid increases white matter repair and neurogenesis after stroke
Liu, X., Chopp, M., Kassis, H., Jia, L., Hozeska‐Solgot, A., Zhang, R. L., Chen, C., Cui, Y. S., & Zhang, Z. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.06.012 · Cited by 111 · see citing works
Oligodendrocyte Dysfunction after Induction of Experimental Anterior Optic Nerve Ischemia
Goldenberg‐Cohen, N., Guo, Y., Margolis, F. L., Cohen, Y., Miller, N. R., & Bernstein, S. L. (2005) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.04-0547 · Cited by 107 · see citing works
The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke
Bonfanti, E., Gelosa, P., Fumagalli, M., Dimou, L., Viganò, F., Tremoli, E., Cimino, M., Sironi, L., & Abbracchio, M. P. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.256 · Cited by 106 · see citing works
Erythropoietin Amplifies Stroke-Induced Oligodendrogenesis in the Rat
Zhang, L., Chopp, M., Zhang, R. L., Wang, L., Zhang, J., Wang, Y., Toh, Y., Santra, M., Lü, M., & Zhang, Z. G. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011016 · Cited by 103 · see citing works
Movement and structure of mitochondria in oligodendrocytes and their myelin sheaths
Rinholm, J. E., Vervaeke, K., Tadross, M. R., Tkachuk, A. N., Kopek, B. G., Brown, T. A., Bergersen, L. H., & Clayton, D. A. (2016) · Glia · doi:10.1002/glia.22965 · Cited by 102 · see citing works
Regeneration of the central nervous system using endogenous repair mechanisms
Okano, H., Sakaguchi, M., Ohki, K., Suzuki, N., & Sawamoto, K. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04674.x · Cited by 103 · see citing works
Synapses on NG2‐expressing progenitors in the brain: multiple functions?
Gallo, V., Mangin, J., Kukley, M., & Dietrich, D. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.158436 · Cited by 97 · see citing works
Glial Cells as Therapeutic Approaches in Brain Ischemia-Reperfusion Injury
Hernández, I. H., Villa-González, M., Martín-López, G., Soto, M. S., & Pérez-Álvarez, M. J. (2021) · Cells · doi:10.3390/cells10071639 · Cited by 94 · see citing works
Insulin‐like growth factor‐1 abrogates microglial oxidative stress and TNF ‐α responses to spreading depression
Grinberg, Y. Y., Dibbern, M. E., Levasseur, V. A., & Kraig, R. P. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12267 · Cited by 94 · see citing works
Effect of Blast Exposure on the Brain Structure and Cognition in Macaca fascicularis
Lu, J., Ng, K. C., Ling, G. S. F., Wu, J., Poon, D. J. F., Kan, E. M., Tan, M. H., Wu, Y., Li, P., Moochhala, S., et al. (2011) · Journal of Neurotrauma · doi:10.1089/neu.2010.1591 · Cited by 93 · see citing works
Blood-Brain Barrier Alterations Provide Evidence of Subacute Diaschisis in an Ischemic Stroke Rat Model
Garbuzova-Davis, S. N., Rodrigues, M. C. O., Hernandez‐Ontiveros, D. G., Tajiri, N., Frisina-Deyo, A. J., Boffeli, S. M., Abraham, J. V., Pabon, M. M., Wagner, A. L., Ishikawa, H., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063553 · Cited by 93 · see citing works
Oligodendrocyte Birth and Death following Traumatic Brain Injury in Adult Mice
Dent, K. A., Christie, K. J., Bye, N., Basrai, H. S., Turbić, A., Habgood, M. D., Cate, H. S., & Turnley, A. M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0121541 · Cited by 93 · see citing works
Ascl1 lineage cells contribute to ischemia-induced neurogenesis and oligodendrogenesis
Zhang, R. L., Chopp, M., Roberts, C., Jia, L., Wei, M., Lu, M., Wang, X., Pourabdollah, S., & Zhang, Z. G. (2011) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2010.134 · Cited by 91 · see citing works
The Endocannabinoid System and Oligodendrocytes in Health and Disease
Ilyasov, A. A., Milligan, C. E., Pharr, E., & Howlett, A. C. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00733 · Cited by 91 · see citing works
Selective adenosine A2a receptor antagonism reduces JNK activation in oligodendrocytes after cerebral ischaemia
Melani, A., Cipriani, S., Vannucchi, M. G., Nosi, D., Donati, C., Bruni, P., Giovannini, M. G., & Pedata, F. (2009) · Brain · doi:10.1093/brain/awp076 · Cited by 91 · see citing works
Pushing Forward: Remyelination as the New Frontier in CNS Diseases
Kremer, D., Göttle, P., Hartung, H., & Küry, P. (2016) · Trends in Neurosciences · doi:10.1016/j.tins.2016.02.004 · Cited by 89 · see citing works
Mitochondrial Behavior in Axon Degeneration and Regeneration
Wang, B., Huang, M., Shang, D., Yan, X., Zhao, B., & Zhang, X. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.650038 · Cited by 90 · see citing works
Physical Exercise Improves Cognitive Function Together with Microglia Phenotype Modulation and Remyelination in Chronic Cerebral Hypoperfusion
Jiang, T., Zhang, L., Pan, X., Zheng, H., Chen, X., Li, L., Luo, J., & Hu, X. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00404 · Cited by 90 · see citing works
Thymosin β4 improves functional neurological outcome in a rat model of embolic stroke
Morris, D. C., Chopp, M., Zhang, L., Lü, M., & Zhang, Z. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.05.017 · Cited by 90 · see citing works
Microenvironmental regulation of oligodendrocyte replacement and remyelination in spinal cord injury
Alizadeh, A., & Karimi‐Abdolrezaee, S. (2016) · The Journal of Physiology · doi:10.1113/jp270895 · Cited by 89 · see citing works
Neuroinflammation in Glaucoma and Optic Nerve Damage
Nair, C. E. M., & Nickells, R. W. (2015) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2015.06.010 · Cited by 86 · see citing works
Models That Matter: White Matter Stroke Models
Sözmen, E. G., Hinman, J. D., & Carmichael, S. T. (2012) · Neurotherapeutics · doi:10.1007/s13311-012-0106-0 · Cited by 84 · see citing works
Oligodendrocyte Progenitor Cell Susceptibility to Injury in Multiple Sclerosis
Cui, Q., Kuhlmann, T., Miron, V. E., Leong, S. Y., Fang, J. Q., Gris, P., Kennedy, T. E., Almazán, G., & Antel, J. P. (2013) · American Journal Of Pathology · doi:10.1016/j.ajpath.2013.04.016 · Cited by 85 · see citing works
White Matter Injury After Subarachnoid Hemorrhage
Egashira, Y., Zhao, H., Hua, Y., Keep, R. F., & Xi, G. (2015) · Stroke · doi:10.1161/strokeaha.115.010351 · Cited by 85 · see citing works
L-Carnitine Enhances Axonal Plasticity and Improves White-Matter Lesions after Chronic Hypoperfusion in Rat Brain
Ueno, Y., Koike, M., Shimada, Y., Shimura, H., Hira, K., Tanaka, R., Uchiyama, Y., Hattori, N., & Urabe, T. (2014) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2014.210 · Cited by 84 · see citing works
NMDA Receptors in Glial Cells: Pending Questions
Džamba, D., Honsa, P., & Anděrová, M. (2013) · Current Neuropharmacology · doi:10.2174/1570159x11311030002 · Cited by 81 · see citing works
CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17
Fumagalli, M., Lecca, D., & Abbracchio, M. P. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.10.005 · Cited by 81 · see citing works
Testing NMDA receptor block as a therapeutic strategy for reducing ischaemic damage to CNS white matter
Bakiri, Y., Hamilton, N. B., Káradóttir, R. T., & Attwell, D. (2007) · Glia · doi:10.1002/glia.20608 · Cited by 81 · see citing works
An abnormal periventricular magnetization transfer ratio gradient occurs early in multiple sclerosis
Brown, J. W. L., Pardini, M., Brownlee, W. J., Fernando, K., Samson, R. S., Prados, F., Sebastien Ourselin, A., Wheeler‐Kingshott, C. A. M. G., Miller, D. H., & Chard, D. (2016) · Brain · doi:10.1093/brain/aww296 · Cited by 81 · see citing works
Promoting brain remodeling to aid in stroke recovery
Zhang, Z. G., & Chopp, M. (2015) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2015.07.005 · Cited by 78 · see citing works
Revealing Spatial and Temporal Patterns of Cell Death, Glial Proliferation, and Blood-Brain Barrier Dysfunction Around Implanted Intracortical Neural Interfaces
Wellman, S. M., Li, L., Yaxiaer, Y., McNamara, I., & Kozai, T. D. Y. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00493 · Cited by 76 · see citing works
Oxidative stress and executive function in children receiving chemotherapy for acute lymphoblastic leukemia
Caron, J. E., Krull, K. R., Hockenberry, M. J., Jain, N., Kaemingk, K. L., & Moore, I. M. (2009) · Pediatric Blood & Cancer · doi:10.1002/pbc.22128 · Cited by 77 · see citing works
OLIGODENDROCYTE VULNERABILITY FOLLOWING TRAUMATIC BRAIN INJURY IN RATS
Lotocki, G., Vaccari, J. P. D. R., Alonso, O., Molano, J. S., Nixon, R., Safavi, P., Dietrich, W., & Bramlett, H. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.05.056 · Cited by 79 · see citing works
Surface-in pathology in multiple sclerosis: a new view on pathogenesis?
Pardini, M., Brown, J. W. L., Magliozzi, R., Reynolds, R., & Chard, D. (2021) · Brain · doi:10.1093/brain/awab025 · Cited by 76 · see citing works
Glial function (and dysfunction) in the normal & ischemic brain
Magaki, S., Williams, C. K., & Vinters, H. V. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.11.009 · Cited by 74 · see citing works
Effect of Polyphenols on Oxidative Stress and Mitochondrial Dysfunction in Neuronal Death and Brain Edema in Cerebral Ischemia
Panickar, K. S., & Anderson, R. A. (2011) · International Journal of Molecular Sciences · doi:10.3390/ijms12118181 · Cited by 73 · see citing works
Neuroplasticity in mood disorders
Drevets, W. C. (2004) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2004.6.2/wdrevets · Cited by 73 · see citing works
Oligovascular Signaling in White Matter Stroke
Arai, K., & Lo, E. H. (2009) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.32.1639 · Cited by 70 · see citing works
Sildenafil Enhances Neurogenesis and Oligodendrogenesis in Ischemic Brain of Middle-Aged Mouse
Zhang, R. L., Chopp, M., Roberts, C. J., Wei, M., Wang, X., Liu, X., Lü, M., & Zhang, Z. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048141 · Cited by 71 · see citing works
Mechanisms of Neurovascular Dysfunction in Acute Ischemic Brain
Terasaki, Y., Liu, Y., Hayakawa, K., Pham, L. D., Lo, E. H., Ji, X., & Arai, K. (2014) · Current Medicinal Chemistry · doi:10.2174/0929867321666131228223400 · Cited by 70 · see citing works
Polynucleotide kinase–phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability
Shimada, M., Dumitrache, L. C., Russell, H. R., & McKinnon, P. J. (2015) · The EMBO Journal · doi:10.15252/embj.201591363 · Cited by 65 · see citing works
Human Traumatic Brain Injury Results in Oligodendrocyte Death and Increases the Number of Oligodendrocyte Progenitor Cells
Flygt, J., Gumucio, A., Ingelsson, M., Skoglund, K., Holm, J., Alafuzoff, I. I., & Marklund, N. (2016) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlw025 · Cited by 67 · see citing works
Effects of long-term treatment on brain volume in patients with obstructive sleep apnea syndrome
Kim, H., Joo, E.-Y., Suh, S. A., Kim, J., Kim, S. T., & Hong, S. B. (2015) · Human Brain Mapping · doi:10.1002/hbm.23038 · Cited by 68 · see citing works
Spatiotemporal evolution of blood brain barrier damage and tissue infarction within the first 3h after ischemia onset
Jin, X., Liu, J., Yang, Y. R., Liu, K. J., Yang, Y., & Liu, W. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.07.007 · Cited by 65 · see citing works
Chronic demyelination-induced seizures
Lapato, A. S., Szu, J. I., Hasselmann, J., Khalaj, A. J., Binder, D. K., & Tiwari-Woodruff, S. K. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.01.035 · Cited by 67 · see citing works
Inhibition of oligodendrocyte precursor cell differentiation by myelin-associated proteins
Syed, Y. A., Baer, A. S., Lübec, G., Hoeger, H., Widhalm, G., & Kotter, M. (2008) · Neurosurgical FOCUS · doi:10.3171/foc/2008/24/3-4/e4 · Cited by 65 · see citing works
Ex Vivo Diffusion Tensor Imaging and Neuropathological Correlation in a Murine Model of Hypoxia–Ischemia-Induced Thrombotic Stroke
Shereen, A. D., Nemkul, N., Yang, D., Adhami, F., Dunn, R. S., Hazen, M. L., Nakafuku, M., Ning, G., Lindquist, D. M., & Kuan, C.-Y. (2010) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2010.212 · Cited by 63 · see citing works
HIV-1 infection alters energy metabolism in the brain: Contributions to HIV-associated neurocognitive disorders
Cotto, B., Natarajanseenivasan, K., & Langford, D. (2019) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2019.101616 · Cited by 63 · see citing works
Treadmill exercise promotes neurogenesis and myelin repair via upregulating Wnt/β‑catenin signaling pathways in the juvenile brain following focal cerebral ischemia/reperfusion
Cheng, J., Shen, W., Jin, L., Pan, J., Zhou, Y., Pan, G., Xie, Q., Hu, Q., Wu, S., Zhang, H., et al. (2020) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2020.4515 · Cited by 63 · see citing works
Tissue inhibitor of metalloproteinases-3 mediates the death of immature oligodendrocytes via TNF-α/TACE in focal cerebral ischemia in mice
Yang, Y. R., Jalal, F. Y., Thompson, J. F., Walker, E. J., Candelario‐Jalil, E., Li, L., Reichard, R. R., Ben, C., Sang, Q. A., Cunningham, L. A., et al. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-108 · Cited by 62 · see citing works
Current concepts in organic acidurias: understanding intra‐ and extracerebral disease manifestation
Kölker, S., Burgard, P., Sauer, S. W., & Okun, J. G. (2013) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-013-9600-8 · Cited by 62 · see citing works
Cellular Mechanisms Participating in Brain Repair of Adult Zebrafish and Mammals after Injury
Ghaddar, B., Lübke, L., Couret, D., Rastegar, S., & Diotel, N. (2021) · Cells · doi:10.3390/cells10020391 · Cited by 60 · see citing works
Regulation of CNS precursor function by neuronal chemokines
Watson, A. E. S., Goodkey, K., Footz, T. K., & Voronova, A. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134533 · Cited by 57 · see citing works
Aberrant oligodendroglial LDL receptor orchestrates demyelination in chronic cerebral ischemia
Xie, Y., Zhang, X., Xu, P., Zhao, N., Zhao, Y., Li, Y., Hong, Y., Peng, M., Yuan, K., Wan, T., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci128114 · Cited by 57 · see citing works
Cofilin as a Promising Therapeutic Target for Ischemic and Hemorrhagic Stroke
Alhadidi, Q., Sayeed, M. S. B., & Shah, Z. A. (2015) · Translational Stroke Research · doi:10.1007/s12975-015-0438-2 · Cited by 57 · see citing works
Oligodendrocytes in intracerebral hemorrhage
Kang, M., & Yao, Y. (2019) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13193 · Cited by 57 · see citing works
Hot Spots for the Use of Intranasal Insulin: Cerebral Ischemia, Brain Injury, Diabetes Mellitus, Endocrine Disorders and Postoperative Delirium
Shpakov, A. O., Zorina, I. I., & Derkach, K. V. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043278 · Cited by 57 · see citing works
Neurovascular-glymphatic dysfunction and white matter lesions
Sabayan, B., & Westendorp, R. G. J. (2021) · GeroScience · doi:10.1007/s11357-021-00361-x · Cited by 54 · see citing works
Netrin-1 Overexpression Promotes White Matter Repairing and Remodeling after Focal Cerebral Ischemia in Mice
He, X., Li, Y., Lu, H., Zhang, Z., Wang, Y., & Yang, G. (2013) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2013.150 · Cited by 54 · see citing works
Quantitative assessment of demyelination in ischemic stroke in vivo using macromolecular proton fraction mapping
Khodanovich, M. Y., Kisel, A. A., Евгеньевич, А. А., Atochin, D. N., Kudabaeva, M., Glazacheva, V., Светлик, М. В., Medvednikova, Y. A., Mustafina, L. R., & Yarnykh, V. L. (2018) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x18755203 · Cited by 54 · see citing works
The Tryptophan-Kynurenine Metabolic System Is Suppressed in Cuprizone-Induced Model of Demyelination Simulating Progressive Multiple Sclerosis
Polyák, H., Galla, Z., Nánási, N., Cseh, E. K., Rajda, C., Veres, G., Spekker, E., Szabó, Á., Klivènyi, P., Tanaka, M., et al. (2023) · Biomedicines · doi:10.3390/biomedicines11030945 · Cited by 53 · see citing works

Oligodendrocyte Pathophysiology and Treatment Strategies in Cerebral Ischemia
Mifsud, G., Zammit, C., Muscat, R., Giovanni, G. D., & Valentino, M. (2014) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12263 · Cited by 118 · see citing works
New insights into the roles of oligodendrocytes regulation in ischemic stroke recovery
Huang, S., Ren, C., Luo, Y., Ding, Y., Ji, X., & Li, S. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106200 · Cited by 52 · see citing works
Oligodendrocyte and Schwann Cell Injury
Ness, J. K., & Goldberg, M. P. (2004) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195152227.003.0034 · Cited by 1 · see citing works
Self-citation
Oligodendrocyte degeneration and recovery after focal cerebral ischemia
McIver, S. R., Muccigrosso, M. M., Gonzales, E. R., Lee, J., Roberts, M. S., Sands, M. S., & Goldberg, M. P. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.04.070 · Cited by 73 · see citing works
Self-citation
Advances in Oligoprotection
Liao, H., & Mani, D. S. (2011) · Neuroscience &amp Medicine · doi:10.4236/nm.2011.22014

Authors: Dewar, D., Underhill, S. M., & Goldberg, M. P.
Affiliations: University of Glasgow (GB)
Washington University in St. Louis (US)
ORCID: Dewar, Deborah
Underhill, Suzanne M.
Goldberg, Mark P.
Venue: Journal of Cerebral Blood Flow & Metabolism
Publisher: SAGE Publications
Published: 2003-03
Volume: 23
Issue: 3
Pages: 263-274
ISSN: 0271-678X (ISSN-L)
1559-7016
DOI: 10.1097/01.wcb.0000053472.41007.f9
OpenAlex: W2077440654
Cited by: 335
References: 123
Citations by year: 2026: 11 · 2025: 11 · 2024: 17 · 2023: 17 · 2022: 14 · 2021: 18 · 2020: 19 · 2019: 20 · 2018: 12 · 2017: 9 · 2016: 24 · 2015: 25 · 2014: 10 · 2013: 23 · 2012: 15
FWCI: 6.35
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: Journal of Cerebral Blood Flow & Metabolism (publishedVersion)
PubMed (publishedVersion)
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
Funders: National Institutes of Health (5r01ns032626-04)
Medical Research Council
National Institute of Neurological Disorders and Stroke (NS 32626, NS36265, R01NS036265)
Topics: Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
Life Sciences › Neuroscience › Neurology › Neurological Disorders and Treatments
Keywords: oligodendrocytes, ischemic brain injury, myelin damage, demyelinating disease, acute cerebral ischemia, oxidative stress, excitatory amino acids, trophic factor deprivation, apoptosis, white matter preservation, immunocytochemical markers
MeSH terms: Animals, Brain Ischemia, Humans, Necrosis, Neurotoxins, Oligodendroglia, Apoptosis, Oxidative Stress, Neuroprotective Agents

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Oligodendrocytes and Ischemic Brain Injury

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks