Cited by 61Gambling Behavior and TreatmentsSubstance Abuse Treatment and OutcomesDecision-Making and Behavioral Economics

The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.

Impaired Decision-Making, Higher Impulsivity, and Drug Severity in Substance Dependence and Pathological Gambling

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Krmpotich, Theodore, Mikulich-Gilbertson, Susan, Sakai, Joseph, Thompson, Laetitia, Banich, Marie T., Tanabe, Jody·2015·Journal of Addiction Medicine

Abstract

OBJECTIVES: Substance use disorder is characterized by impaired decision making, impulsivity, and risk taking. Pathological gambling shares many of these characteristics, and having both diagnoses may be associated with greater problems than either diagnosis alone. We investigated whether among substance-dependent individuals, comorbid pathological gambling would be associated with worse decision making, greater impulsivity, risk taking, and drug severity. METHODS: Ninety-six substance-dependent individuals were recruited from a residential treatment program and divided into 1 of the 2 groups depending on whether they met Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria for pathological gambling (SDPG, n = 26) or not (SD, n = 70). Ninety-two controls were recruited from the community. Participants completed a decision-making task (modified Iowa Gambling Task), measures of impulsivity (Barratt Impulsivity Scale and Delay Discounting), and risk taking (Balloon Analog Risk Task). Decision making was analyzed using a computational model. We tested for group differences using analysis of covariance or Kruskal-Wallis and appropriate post-hoc tests. RESULTS: The groups differed in decision-making parameters (P < 0.001) and self-reported impulsivity (P < 0.001). All post-hoc comparisons were significant on these measures, and indicated stepwise changes in controls, followed by SD, followed by SDPG, with SDPG performing worse on decision making and being more impulsive. Compared with SD, SDPG had greater drug severity (P < 0.001). No group differences were observed in delay discounting or risk taking. CONCLUSIONS: Compared with individuals with substance dependence without pathological gambling, those with both disorders demonstrated worse decision making and significantly more drug-related symptoms. When evaluating patients with substance dependence, clinicians should consider diagnostic assessments for gambling, as the co-occurrence of both disorders may impact clinical characteristics.

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Metadata

Authors
Krmpotich, T., Mikulich-Gilbertson, S., Sakai, J., Thompson, L., Banich, M. T., & Tanabe, J.
Affiliations
University of Colorado Boulder (US)
Corresponding author
Tanabe, Jody
Venue
Journal of Addiction Medicine
Published
2015-07
Volume
9
Issue
4
Pages
273-280
ISSN
1932-0620 (ISSN-L)
OpenAlex
W2320363169
Cited by
61
References
43
Citations by year
2026: 2 · 2025: 6 · 2024: 5 · 2023: 5 · 2022: 8 · 2021: 3 · 2020: 7 · 2019: 4 · 2018: 6 · 2017: 5 · 2016: 10
FWCI
8.68
Type
journal article
Language
en
Open access
Locations
  • Journal of Addiction Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • University of Colorado Denver
  • National Institute on Drug Abuse (R21DA024104, DA02774, DA024104, R01DA027748)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
Keywords
substance dependence, gambling addiction, decision-making, impulsivity, risk-taking, comorbidities, Iowa Gambling Task, delay discounting, Balloon Analogue Risk Task, computational modeling of decision making, Barratt Impulsiveness Scale
MeSH terms
Adult, Decision Making, Female, Gambling, Humans, Impulsive Behavior, Male, Risk-Taking, Comorbidity, Substance-Related Disorders

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