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Effectiveness of a 3-week Multimodal Inpatient Pain Treatment for Adolescents Suffering From Chronic Pain: Statistical and Clinical Significance
Abstract
OBJECTIVE: The present study aimed to investigate the effectiveness of a 3-week multimodal inpatient pain program for children and adolescents with chronic pain. METHODS: Effectiveness was investigated for pain-related variables (pain intensity, pain-related disability) and emotional distress in 3 ways: (1) in terms of statistically significant changes; (2) in terms of the clinical significance of these changes by creating post-hoc outcome groups for pain-related variables and emotional distress; and (3) in terms of the clinically significant overall amelioration generalizing the outcome over 3 variables (ie, pain intensity, pain-related disability, and school absence). One hundred sixty-seven adolescents (aged between 11 and 18 y) with various pain disorders (50% with headache) who met inpatient criteria were evaluated at baseline and 3 months posttreatment. RESULTS: Patients demonstrated statistically significant changes in all variables with large to medium effect sizes. Seventy-two percent and 45% of the patients demonstrated clinically significant changes in pain intensity and pain-related disability, respectively. The percentages of patients demonstrating clinically significant change in emotional distress ranged from 13% to 26%. Seventy-seven adolescents demonstrated overall amelioration. DISCUSSION: Results of the study are promising in at least 2 ways: (1) a multimodal inpatient program might stop the negative effects of chronic pain, disability, and emotional distress in children and adolescents, and (2) the exploration of clinical significance testing has demonstrated utility and can be applied to future effectiveness studies in pediatric pain.
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“Most current psychological and physiotherapeutic treatments for adolescents with chronic pain involve promoting pain coping strategies via psychological interventions, with separate physical therapy prescribed [9].”
Citations
Cites
Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,603
Jacobson, N. S., & Truax, P. (1991) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.59.1.12 · Cited by 7,770
Farrar, J. T., Young, J. P., LaMoreaux, L., Werth, J. L., & Poole, M. R. (2001) · Pain · doi:10.1016/s0304-3959(01)00349-9 · Cited by 5,808
Benjamin, S. (1994) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(94)90012-4 · Cited by 2,001
Pain in children and adolescents: a common experience
Perquin, C. W., Hazebroek-Kampschreur, A. A. J. M., Hunfeld, J. A. M., Bohnen, A. M., van Suijlekom-Smit, L. W. A., Passchier, J., & van der Wouden, J. C. (2000) · Pain · doi:10.1016/s0304-3959(00)00269-4 · Cited by 1,114
Psychotherapie im Wandel: von der Konfession zur Profession
Grawe, K., Donati, R., & Bernauer, F. (2001) · Cited by 772
von Baeyer, C. L., & Spagrud, L. J. (2006) · Pain · doi:10.1016/j.pain.2006.08.014 · Cited by 695
Perepletchikova, F., Treat, T. A., & Kazdin, A. E. (2007) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.75.6.829 · Cited by 533
PALERMO, T. M. (2000) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200002000-00011 · Cited by 494
Normative comparisons for the evaluation of clinical significance.
Kendall, P. C., Marrs, A. L., Nath, S. R., & Sheldrick, R. C. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.67.3.285 · Cited by 468
Eccleston, C., Crombez, G., Scotford, A., Clinch, J., & Connell, H. (2004) · Pain · doi:10.1016/j.pain.2003.11.008 · Cited by 418
Wise, E. A. (2004) · Journal of Personality Assessment · doi:10.1207/s15327752jpa8201_10 · Cited by 399
Parent and family factors in pediatric chronic pain and disability: An integrative approach
Palermo, T. M., & Chambers, C. T. (2005) · Pain · doi:10.1016/j.pain.2005.10.027 · Cited by 384
Normative comparisons for the evaluation of clinical significance.
Kendall, P. C., Marrs-Garcia, A., Nath, S. R., et al. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.67.3.285 · Cited by 350
Sherry, D. D., Wallace, C. A., Kelley, C. A., Kidder, M., & Sapp, L. R. (1999) · Clinical Journal of Pain · doi:10.1097/00002508-199909000-00009 · Cited by 345
Hotopf, M. H., Carr, S., Mayou, R., Wadsworth, M. E. J., & Wessely, S. C. (1998) · BMJ · doi:10.1136/bmj.316.7139.1196 · Cited by 307
Eccleston, C., Morley, S., Williams, A. C. D. C., Yorke, L., & Mastroyannopoulou, K. (2002) · Pain · doi:10.1016/s0304-3959(02)00072-6 · Cited by 295
McCracken, L. M., Gauntlett-Gilbert, J., & Vowles, K. E. (2007) · Pain · doi:10.1016/j.pain.2006.12.013 · Cited by 290
Eccleston, C. (2003) · Archives of Disease in Childhood · doi:10.1136/adc.88.10.881 · Cited by 276
Clinical Significance Methods: A Comparison of Statistical Techniques
Bauer, S., Lambert, M. J., & Nielsen, S. L. (2004) · Journal of Personality Assessment · doi:10.1207/s15327752jpa8201_11 · Cited by 258
Neglected topics in chronic pain treatment outcome studies: determination of success
Turk, D., Rudy, T., & Sorkin, B. A. (1993) · Pain · doi:10.1016/0304-3959(93)90049-u · Cited by 245
Sleed, M., Eccleston, C., Beecham, J., Knapp, M., & Jordan, A. (2005) · Pain · doi:10.1016/j.pain.2005.09.028 · Cited by 244
Haldorsen, E. M. H., Grasdal, A. L., Skouen, J. S., Risa, A. E., Kronholm, K., & Ursin, H. (2002) · Pain · doi:10.1016/s0304-3959(01)00374-8 · Cited by 243
Headache in German Children and Adolescents: A Population-Based Epidemiological Study
Kröner‐Herwig, B., Heinrich, M., & Morris, L. (2007) · Cephalalgia · doi:10.1111/j.1468-2982.2007.01319.x · Cited by 223
Reports of pain among German children and adolescents: an epidemiological study
Roth-Isigkeit, A., Thyen, U., Raspe, H. H., Stöven, H., & Schmucker, P. (2004) · Acta Paediatrica · doi:10.1111/j.1651-2227.2004.tb00717.x · Cited by 218
Assessing Clinical Significance: Proposed Extensions to Method
Tingey, R., Lambert, M. J., Burlingame, G. M., & Hansen, N. B. (1996) · Psychotherapy Research · doi:10.1080/10503309612331331638 · Cited by 198
Interdisciplinary treatment for fibromyalgia syndrome: clinical and statistical significance.
Turk, D. C., Okifuji, A., Sinclair, J., & Starz, T. (1998) · Arthritis care and research : the official journal of the Arthritis Health Professions Association · doi:10.1002/art.1790110306 · Cited by 196
Psychological Treatment of Recurrent Headache in Children and Adolescents - A Meta-Analysis
Trautmann, E., Lackschewitz, H., & Kröner‐Herwig, B. (2006) · Cephalalgia · doi:10.1111/j.1468-2982.2006.01226.x · Cited by 187
Imagination als heilsame Kraft
Reddemann, L. (2003) · Technische Universität Dortmund Eldorado (Technische Universität Dortmund) · doi:10.17877/de290r-2424 · Cited by 170
Matthey, S. (2004) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00313-0 · Cited by 168
McCracken, L. M., MacKichan, F., & Eccleston, C. (2007) · European Journal of Pain · doi:10.1016/j.ejpain.2006.05.004 · Cited by 167 · cited 1×
“0 15%-50% school absence 57 (34) 25 (18)”
Investigation and Treatment of Missing Item Scores in Test and Questionnaire Data
Sijtsma, K., & van der Ark, L. A. (2003) · Multivariate Behavioral Research · doi:10.1207/s15327906mbr3804_4 · Cited by 154
Headache Prevalence Among Adolescents — The German DMKG Headache Study
Fendrich, K., Vennemann, M., Pfaffenrath, V., Evers, S., May, A., Berger, K., & Hoffmann, W. U. (2007) · Cephalalgia · doi:10.1111/j.1468-2982.2007.01289.x · Cited by 153
Managing chronic pain in children and adolescents
Eccleston, C., & Malleson, P. N. (2003) · BMJ · doi:10.1136/bmj.326.7404.1408 · Cited by 148
Perquin, C. W., Hunfeld, J. A. M., Hazebroek-Kampschreur, A. A. J. M., van Suijlekom‐Smit, L. W. A., Passchier, J., Koes, B. W., & van der Wouden, J. C. (2003) · European Journal of Pain · doi:10.1016/s1090-3801(03)00060-0 · Cited by 119
Clinical Assessment and Management of Chronic Pain and Pain-Associated Disability Syndrome
Bursch, B., Walco, G. A., & Zeltzer, L. K. (1998) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-199802000-00008 · Cited by 114
Härkäpää, K., Järvikoski, A., Mellin, G. P., & Hurri, H. (1989) · Journal of Rehabilitation Medicine · doi:10.2340/1650197719898189 · Cited by 111
Rose, J., Loftus, M., Flint, B., & Carey, L. (2005) · British Journal of Clinical Psychology · doi:10.1348/014466505x29972 · Cited by 107
Jacobson, N. S., & Gortner, E. T. (2000) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(99)00029-7 · Cited by 100
Newnham, E. A., Harwood, K. E., & Page, A. C. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.07.001 · Cited by 97
Härkäpää, K., Mellin, G. P., Järvikoski, A., & Hurri, H. (2020) · Journal of Rehabilitation Medicine · doi:10.2340/165019779022181188 · Cited by 93
Statistical Significance Versus Clinical Importance
van Tulder, M. W., Malmivaara, A. O. V., Hayden, J. A., & Koes, B. W. (2007) · Spine · doi:10.1097/brs.0b013e3180b9ef49 · Cited by 83
Children with chronic pain: Impact of sex and age on long-term outcomes
Martin, A. L., McGrath, P. A., Brown, S. C., & Katz, J. (2007) · Pain · doi:10.1016/j.pain.2006.08.027 · Cited by 82
A controlled study of alexithymia in adolescent patients with persistent somatoform pain disorder
Burba, B., Oswald, R., Grigaliunien, V., Neverauskiene, S., Jankuviene, O., & Chue, P. (2006) · The Canadian Journal of Psychiatry · doi:10.1177/070674370605100709 · Cited by 78
Gil, K. M., Wilson, J. J., & Edens, J. L. (1997) · Clinical Journal of Pain · doi:10.1097/00002508-199706000-00005 · Cited by 64
Dobe, M., Damschen, U., Reiffer-Wiesel, B., Sauer, C., & Zernikow, B. (2006) · Der Schmerz · doi:10.1007/s00482-005-0457-0 · Cited by 63
Lutz, W., Martinovich, Z., Howard, K. I., & Leon, S. C. (2002) · Journal of Clinical Psychology · doi:10.1002/jclp.10070 · Cited by 47
Tsao, J. C. I., Lü, Q., Kim, S. C., & Zeltzer, L. K. (2006) · Cognitive Behaviour Therapy · doi:10.1080/16506070600898272 · Cited by 47
Openshaw, C., Waller, G., & Sperlinger, D. J. (2004) · International Journal of Eating Disorders · doi:10.1002/eat.20042 · Cited by 41
Treatment of children with unexplained chronic pain
Kashikar‐Zuck, S. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68118-x · Cited by 40
Treatment of Functional Impairment in Severe Somatoform Pain Disorder: A Case Example
Palermo, T. M. (2001) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/26.7.429 · Cited by 35
Schauenburg, H., & Strack, M. (1998) · PubMed · Cited by 33
Hsu, L. (1996) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/bf02229141 · Cited by 32
Chronic pain in children and adolescents
Eccleston, C., Bruce, E., & Carter, B. (2006) · Nursing Children and Young People · doi:10.7748/paed.18.10.30.s21 · Cited by 30
"Statistical significance and clinical significance are not synonyms!".
Turk, D. (2000) · The Clinical Journal of Pain · doi:10.1097/00002508-200009000-00001 · Cited by 30
Åsenlöf, P., Denison, E., & Lindberg, P. (2006) · Behaviour Research and Therapy · doi:10.1016/j.brat.2005.07.005 · Cited by 26
[Assessment and measurement of pain].
Denecke, H., & Hünseler, C. (2000) · PubMed · doi:10.1007/s004820000022 · Cited by 25
Personality disorders in a Dutch forensic psychiatric sample: changes with treatment
Greeven, P. G. J., & de Ruiter, C. (2004) · Criminal Behaviour and Mental Health · doi:10.1002/cbm.594 · Cited by 24
Risikofaktoren für Rückenschmerzen bei Kindern und Jugendlichen in Industrienationen
Roth-Isigkeit, A., Schwarzenberger, J. C., Baumeier, W., Meier, T., Lindig, M., & Schmucker, P. (2004) · Der Schmerz · doi:10.1007/s00482-004-0379-2 · Cited by 23
Messen und Erfassen von Schmerz
Hechler, T., Denecke, H., Hünseler, C., Schroeder, S., & Zernikow, B. (2009) · Springer eBooks · doi:10.1007/978-3-540-74065-0_5 · Cited by 23
Introduction to the Special Issue on Pain: From Pain to Pain-Associated Disability Syndrome
Zeltzer, L. K., Tsao, J. C. I., Bursch, B., & Myers, C. D. (2005) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsj053 · Cited by 22
Messen und Erfassen von Schmerz
Denecke, H., & Hünseler, C. (2000) · Der Schmerz · doi:10.1007/s004820070016 · Cited by 22
Statistical significance versus clinical importance.
Prasad, K. (1994) · Stroke · doi:10.1161/str.25.7.1527b · Cited by 19
Rosqvist, J., Thomas, J. C., & Egan, D. (2002) · Behavior Modification · doi:10.1177/0145445502026002005 · Cited by 16
The Effectiveness of Hospitalization in the Treatment of Paediatric Idiopathic Headache Patients
Lanzi, G., D’Arrigo, S., Termine, C., Rossi, M., Ginevra, O. F., Mongelli, A., Millul, A., & Beghi, E. (2006) · Psychopathology · doi:10.1159/000096383 · Cited by 15
Pediatric Headache: An Examination of Process Variables in Treatment
Cvengros, J. A., Harper, D. C., & Shevell, M. I. (2007) · Journal of Child Neurology · doi:10.1177/0883073807305786 · Cited by 12
Bringing pain relief to children: a guide to practical management
Newman, C. J. (2007) · PubMed Central · doi:10.1136/adc.2006.103168 · Cited by 4
What's in a Face: Can parents “read pain” in their children's faces?
Zeltzer, L. K., & Tsao, J. C. I. (2006) · Pain · doi:10.1016/j.pain.2006.07.007 · Cited by 2
Research works printed but not linked: 1
- Hagenah, 2005, Somatisierungsstörungen bei Kindern und Jugendlichen, Deutsches Ärzteblatt, 8, 361
Cited by
Sorted by citations
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Hechler, T., Kanstrup, M., Holley, A. L., Simons, L. E., Wicksell, R., Hirschfeld, G., & Zernikow, B. (2015) · Pediatrics · doi:10.1542/peds.2014-3319 · Cited by 230
Zernikow, B., Wager, J., Hechler, T., Hasan, C., Rohr, U., Dobe, M., Meyer, A., Hübner-Möhler, B., Wamsler, C., & Blankenburg, M. (2012) · BMC Pediatrics · doi:10.1186/1471-2431-12-54 · Cited by 214
Self-citationHechler, T., Ruhe, A., Schmidt, P., Hirsch, J., Wager, J., Dobe, M., Krummenauer, F., & Zernikow, B. (2013) · Pain · doi:10.1016/j.pain.2013.09.015 · Cited by 175
Logan, D. E., Carpino, E. A., Chiang, G., Condon, M., Firn, E., Gaughan, V. J., Hogan, M., Leslie, D. S., Olson, K., Sager, S., et al. (2012) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e3182457619 · Cited by 152
Managing Chronic Pain in Children and Adolescents: A Clinical Review
Landry, B. W., Fischer, P. R., Driscoll, S. W., Koch, K. M., Harbeck‐Weber, C., Mack, K. J., Wilder, R. T., Bauer, B. A., & Brandenburg, J. E. (2015) · PM&R · doi:10.1016/j.pmrj.2015.09.006 · Cited by 128
Metadata
- Authors
- Hechler, T., Dobe, M., Kosfelder, J., Damschen, U., Hübner, B., Blankenburg, M., Sauer, C., & Zernikow, B.
- Affiliations
- Vodafone Foundation (GB)
- Hochschule Düsseldorf University of Applied Sciences (DE)
- Corresponding author
- Hechler, Tanja
- Dobe, Michael
- Damschen, Uta
- Hübner, Bettina
- Blankenburg, Markus
- Zernikow, Boris
- Venue
- The Clinical Journal of Pain
- Published
- 2009-02
- Volume
- 25
- Issue
- 2
- Pages
- 156-166
- ISSN
- 0749-8047 (ISSN-L)
- OpenAlex
- W2019118209
- Cited by
- 130
- References
- 71
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 4 · 2022: 2 · 2021: 6 · 2020: 8 · 2019: 10 · 2018: 5 · 2017: 8 · 2016: 14 · 2015: 7 · 2014: 7 · 2013: 19 · 2012: 16
- FWCI
- 9.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Journal of Pain (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- chronic pain, adolescents, multimodal pain management, pain intensity, pain-related disability, emotional distress, headache, school absenteeism, pediatric pain
- MeSH terms
- Adolescent, Child, Chronic Disease, Combined Modality Therapy, Emotions, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Pain, Severity of Illness Index, Reproducibility of Results, Treatment Outcome, Young Adult, Pain Management
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