Weight loss after bariatric surgery improves aortic elastic properties and left ventricular function in individuals with morbid obesity: a 3-year follow-up study
Abstract
OBJECTIVE: To investigate whether weight loss after bariatric surgery (gastric bypass) is associated with changes in aortic function (an important determinant of left ventricular function) and in left ventricular function, in morbidly obese individuals 3 and 36 months after surgery. METHODS: We used echocardiography to evaluate 60 obese individuals [body mass index (BMI) > 40 kg/m2] who underwent surgery and 20 obese individuals who neither underwent surgery nor lost weight, at baseline and at 3 and 36 months of follow-up, and 40 lean individuals (BMI < 25 kg/m2) of similar age, sex and risk factors, at baseline. We measured aortic strain, distensibility, stiffness index, pressure-strain modulus and Doppler indices of left ventricular diastolic dysfunction (ratio of peak early to peak atrial flow velocities, isovolumic relaxation time and deceleration time). RESULTS: Baseline aortic function and Doppler diastolic indices were impaired in obese individuals compared with those who were lean (P < 0.05). During 3 and 36 months of follow-up, BMI and left ventricular diastolic diameter, volume, mass and wall thickness were reduced, and indices of aortic function and left ventricular diastolic function were normalized, in obese individuals after surgery [aortic distensibility (cm2 x dyn(-1) x 10(-6)): 1.9 before surgery, 3.4 at 3 months after surgery and 4.3 at 3 years after surgery, compared with 3.36 in lean controls; P < 0.01], but not in those who did not lose weight. The reduction in BMI after surgery was related to the concomitant improvement in indices of aortic function (P < 0.01) and isovolumic relaxation time (P < 0.05) after adjustment for age, sex and concomitant reduction in blood pressure, lipids and glucose concentrations. CONCLUSION: Weight reduction after bariatric surgery normalizes aortic function, reduces left ventricular hypertrophy and, thus, improves left ventricular diastolic function in morbidly obese individuals over a 3-year period of follow-up.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A total of 8 articles were used across more than 1 component.
“A total of 8 articles were used across more than 1 component.141,142,144,148,156,159,168,169”
From 2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults (2014) · cites this paper as [148]
A total of 10 studies (12 articles) met the inclusion criteria, were rated as good or fair quality, and are included in the summary table.
“A total of 10 studies (12 articles) met the inclusion criteria, were rated as good or fair quality, and are included in the summary table.141,142,144,148,151,155,156,159,161,168,169,172”
From 2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults (2014) · cites this paper as [148]
Cites
Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans
Considine, R. V., Sinha, M. K., Heiman, M. L., Kriauciunas, A., Stephens, T. W., Nyce, M. R., Ohannesian, J. P., Marco, C. C., McKee, L. J., Bauer, T. L., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199602013340503 · Cited by 6,326 · see citing works
Prevalence and trends in obesity among US adults, 1999–2000
Flegal, K. M. (2002) · JAMA · doi:10.1001/jama.288.14.1723 · Cited by 6,190 · see citing works
Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method.
Devereux, R. B., & Reichek, N. (1977) · Circulation · doi:10.1161/01.cir.55.4.613 · Cited by 4,499 · see citing works
Laurent, S., Boutouyrie, P., Asmar, R., Gautier, I., Laloux, B., Guize, L., Ducimetiere, P., & Benetos, A. (2001) · Hypertension · doi:10.1161/01.hyp.37.5.1236 · Cited by 3,856 · see citing works
Obesity and insulin resistance
Kahn, B. B., & Flier, J. S. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10842 · Cited by 3,283 · see citing works
Elevated C-reactive protein levels in overweight and obese adults
Visser, M. (1999) · JAMA · doi:10.1001/jama.282.22.2131 · Cited by 2,494 · see citing works
Impact of Aortic Stiffness on Survival in End-Stage Renal Disease
Blacher, J., Guerin, A. P., Pannier, B., Marchais, S. J., Safar, M. E., & London, G. M. (1999) · Circulation · doi:10.1161/01.cir.99.18.2434 · Cited by 2,138 · see citing works
Angiotensin II receptors and angiotensin II receptor antagonists.
Timmermans, P. B. M. W. M., Wong, P. C., Chiu, A. T., Herblin, W. F., Benfield, P. A., Carini, D. J., Lee, R. J., Wexler, R. R., Saye, J. A., & Smith, R. D. (1993) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)00446-6 · Cited by 1,854 · see citing works
Ziccardi, P., Nappo, F., Giugliano, G., Esposito, K., Marfella, R., Cioffi, M., D’Andrea, F., Molinari, A. M., & Giugliano, D. (2002) · Circulation · doi:10.1161/hc0702.104279 · Cited by 994 · see citing works
Overweight, Obesity, and Health Risk
National Task Force on the Prevention and Treatment of Obesity (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.7.898 · Cited by 963 · see citing works
Nitric oxide release accounts for insulin's vascular effects in humans.
Scherrer, U., Randin, D., Vollenweider, P., Vollenweider, L., & NICOD, P. H. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117621 · Cited by 751 · see citing works
Biliopancreatic Diversion with Duodenal Switch
Marceau, P., Hould, F.-S., Simard, S., Lebel, S., Bourque, R. A., Potvin, M., & Biron, S. (1998) · World Journal of Surgery · doi:10.1007/s002689900498 · Cited by 649 · see citing works
Bénétos, A., Adamopoulos, C., Bureau, J.-M., Temmar, M., Labat, C., Bean, K., Thomas, F., Pannier, B., Asmar, R. G., Zureik, M., et al. (2002) · Circulation · doi:10.1161/hc1002.105135 · Cited by 590 · see citing works
Nitric Oxide Regulates Local Arterial Distensibility In Vivo
Wilkinson, I. B., Qasem, A., McEniery, C. M., Webb, D. J., Avolio, A. P., & Cockcroft, J. R. (2002) · Circulation · doi:10.1161/hc0202.101970 · Cited by 502 · see citing works
Behrendt, D., & Ganz, P. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)02963-6 · Cited by 499 · see citing works
Measures of Obesity Are Associated With Vascular Stiffness in Young and Older Adults
Wildman, R. P., Mackey, R. H., Bostom, A., Thompson, T., & Sutton-Tyrrell, K. (2003) · Hypertension · doi:10.1161/01.hyp.0000090360.78539.cd · Cited by 441 · see citing works
Insulin Causes Endothelial Dysfunction in Humans: Sites and Mechanisms
Arcaro, G., Cretti, A., Balzano, S., Lechi, A., Muggeo, M., Bonora, E., & Bonadonna, R. C. (2002) · Circulation · doi:10.1161/hc0502.103333 · Cited by 407 · see citing works
Hundley, W. G., Kitzman, D. W., Morgan, T. M., Hamilton, C. A., Darty, S. N., Stewart, K. P., Herrington, D. M., Link, K. M., & Little, W. C. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01447-4 · Cited by 386 · see citing works
Ward, M. R., Pasterkamp, G., Yeung, A. C., & Borst, C. (2000) · Circulation · doi:10.1161/01.cir.102.10.1186 · Cited by 378 · see citing works
Influence of Excess Fat on Cardiac Morphology and Function: Study in Uncomplicated Obesity
Iacobellis, G., Ribaudo, M. C., Leto, G., Zappaterreno, A., Vecci, E., Di Mario, U., & Leonetti, F. (2002) · Obesity Research · doi:10.1038/oby.2002.104 · Cited by 257 · see citing works
Stefanadis, C. (2000) · European Heart Journal · doi:10.1053/euhj.1999.1756 · Cited by 217 · see citing works
Eren, M., Gorgulu, S., Uslu, N., Celik, S., Dagdeviren, B., & Tezel, T. (2003) · Heart · doi:10.1136/heart.90.1.37 · Cited by 216 · see citing works
Weight Change Is Associated With Change in Arterial Stiffness Among Healthy Young Adults
Wildman, R. P., Farhat, G. N., Patel, A. S., Mackey, R. H., Brockwell, S. E., Thompson, T., & Sutton-Tyrrell, K. (2005) · Hypertension · doi:10.1161/01.hyp.0000152200.10578.5d · Cited by 176 · see citing works
Nigam, A., Mitchell, G. F., Lambert, J., & Tardif, J. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(03)00656-8 · Cited by 155 · see citing works
Zureik, M., Temmar, M., Adamopoulos, C., Bureau, J.-M., Courbon, D., Thomas, F., Bean, K., Touboul, P., Ducimetière, P., & Bénétos, A. (2002) · Journal of Hypertension · doi:10.1097/00004872-200201000-00013 · Cited by 154 · see citing works
Aortic stiffness in young patients with heterozygous familial hypercholesterolemia
Pitsavos, C. E., Toutouzas, K. P., Dernellis, J. M., Skoumas, J., Skoumbourdis, E., Stefanadis, C., & TOUTOUZAS, P. K. (1998) · American Heart Journal · doi:10.1016/s0002-8703(98)70274-1 · Cited by 134 · see citing works
Review: Arterial stiffness and the renin-angiotensin-aldosterone system
Mahmud, A., & Feely, J. (2004) · Journal of the Renin-Angiotensin-Aldosterone System · doi:10.3317/jraas.2004.025 · Cited by 117 · see citing works
Alpert, M., Lambert, C. R., Terry, B. E., Cohen, M. V., Mukerji, V., Massey, C. V., Hashimi, M. W., & Panayiotou, H. (1995) · American Heart Journal · doi:10.1016/0002-8703(95)90210-4 · Cited by 97 · see citing works
The influence of obesity on left ventricular filling and systolic function
Stoddard, M. F., Tseuda, K., Thomas, M., Dillon, S., & Kupersmith, J. (1992) · American Heart Journal · doi:10.1016/0002-8703(92)90280-9 · Cited by 96 · see citing works
Danias, P. G., Tritos, N. A., Stuber, M., Botnar, R. M., Kissinger, K. V., & Manning, W. J. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)03109-0 · Cited by 95 · see citing works
Arterial Stiffness Increases During Obstructive Sleep Apneas
Jelić, S., Bartels, M. N., Mateika, J. H., Ngai, P., DeMeersman, R. E., & Basner, R. C. (2002) · SLEEP · doi:10.1093/sleep/25.8.15 · Cited by 94 · see citing works
Role of Adipose Tissue for Cardiovascular-Renal Regulation in Health and Disease
Engeli, S., & Sharma, A. M. (2000) · Hormone and Metabolic Research · doi:10.1055/s-2007-978675 · Cited by 89 · see citing works
Ikonomidis, I., Lekakis, J. P., Stamatelopoulos, K. S., Markomihelakis, N., Kaklamanis, P. G., & Mavrikakis, M. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.10.042 · Cited by 89 · see citing works
Self-citationter Maaten, J. C., Bakker, S. J. L., Serné, E. H., ter Wee, P. M., Donker, A. J. M., & Gans, R. O. B. (1999) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/14.10.2357 · Cited by 60 · see citing works
Prospective evaluation of biliopancreatic diversion with Roux-en-Y gastric bypass in the super obese
Kalfarentzos, F. E., Papadoulas, S., Skroubis, G., Kehagias, I., Loukidi, A., & Mead, N. (2004) · Journal of Gastrointestinal Surgery · doi:10.1016/j.gassur.2003.11.022 · Cited by 32 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults
Jensen, M. D., Ryan, D. H., Apovian, C. M., Ard, J. D., Comuzzie, A. G., Donato, K. A., Hu, F. B., Hubbard, V. S., Jakicic, J. M., Kushner, R. F., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.11.004 · Cited by 4,058 · see citing works
2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults
Jensen, M. D., Ryan, D. H., Apovian, C. M., Ard, J. D., Comuzzie, A. G., Donato, K. A., Hu, F. B., Hubbard, V. S., Jakicic, J. M., Kushner, R. F., et al. (2014) · Circulation · doi:10.1161/01.cir.0000437739.71477.ee · Cited by 2,735 · see citing works
“A total of 8 articles were used across more than 1 component.(141,142,144,148,156,159,168,169)”
BackgroundIkonomidis, I., Aboyans, V., Blacher, J., Brodmann, M., Brutsaert, D. L., Chirinos, J. A., Carlo, M. D., Delgado, V., Lancellotti, P., Lekakis, J. P., et al. (2019) · European Journal of Heart Failure · doi:10.1002/ejhf.1436 · Cited by 396 · see citing works
Self-citationObesity cardiomyopathy: evidence, mechanisms, and therapeutic implications
Ren, J. T., Wu, N. N., Wang, S., Sowers, J. R., & Zhang, Y. (2021) · Physiological Reviews · doi:10.1152/physrev.00030.2020 · Cited by 377 · see citing works
Bariatric surgery and cardiovascular outcomes: a systematic review
Vest, A. R., Heneghan, H. M., Agarwal, S., Schauer, P. R., & Young, J. B. (2012) · Heart · doi:10.1136/heartjnl-2012-301778 · Cited by 336 · see citing works
Executive summary: Guidelines (2013) for the management of overweight and obesity in adults
Members, E. P., Jensen, M. D., Ryan, D. H., Donato, K. A., Apovian, C. M., Ard, J. D., Comuzzie, A. G., Hu, F. B., Hubbard, V. S., Jakicic, J. M., et al. (2014) · Obesity · doi:10.1002/oby.20821 · Cited by 337 · see citing works
Hammer, S., Snel, M., Lamb, H. J., Jazet, I. M., van der Meer, R. W., Pijl, H., Meinders, E. A., Romijn, J. A., Roos, A., & Smit, J. W. A. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.04.068 · Cited by 264 · see citing works
Expert panel report: Guidelines (2013) for the management of overweight and obesity in adults
(2014) · Obesity · doi:10.1002/oby.20660 · Cited by 257 · see citing works
Impact of Obesity and Weight Loss on Cardiac Performance and Morphology in Adults
Alpert, M., Omran, J., Mehra, A., & Ardhanari, S. (2013) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2013.09.003 · Cited by 243 · see citing works
Effects of Bariatric Surgery on Cardiovascular Function
Ashrafian, H., le Roux, C. W., Darzi, A. W., & Athanasiou, T. (2008) · Circulation · doi:10.1161/circulationaha.107.721027 · Cited by 228 · see citing works
Murine Models of Heart Failure With Preserved Ejection Fraction
Valero‐Muñoz, M., Backman, W., & Sam, F. (2017) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2017.07.013 · Cited by 207 · see citing works
Reversibility of Cardiac Abnormalities in Morbidly Obese Adolescents
Ippisch, H. M., Inge, T. H., Daniels, S. R., Wang, B., Khoury, P. R., Witt, S. A., Glascock, B. J., Garcia, V. F., & Kimball, T. R. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.12.029 · Cited by 191 · see citing works
Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential
Martin, T. G., Juarros, M. A., & Leinwand, L. A. (2023) · Nature Reviews Cardiology · doi:10.1038/s41569-022-00806-6 · Cited by 180 · see citing works
Aggarwal, R., Harling, L., Efthimiou, E., Darzi, A. W., Athanasiou, T., & Ashrafian, H. (2015) · Obesity Surgery · doi:10.1007/s11695-015-1866-5 · Cited by 159 · see citing works
Ricci, C., Gaeta, M., Rausa, E., Asti, E., Bandera, F., & Bonavina, L. (2014) · Obesity Surgery · doi:10.1007/s11695-014-1442-4 · Cited by 139 · see citing works
Obesity and hypertension: mechanisms, cardio-renal consequences, and therapeutic approaches.
Reisin, E., & Jack, A. (2009) · The Medical clinics of North America · doi:10.1016/j.mcna.2009.02.010 · Cited by 114 · see citing works
Cuspidi, C., Rescaldani, M., Tadić, M., Sala, C., & Grassi, G. (2013) · American Journal of Hypertension · doi:10.1093/ajh/hpt215 · Cited by 117 · see citing works
Mahajan, R., Stokes, M. B., Elliott, A. D., Munawar, D. A., Khokhar, K. B., Thiyagarajah, A., Hendriks, J., Linz, D., Gallagher, C., Kaye, D. M., et al. (2019) · Heart · doi:10.1136/heartjnl-2019-314770 · Cited by 120 · see citing works
Diastolic Dysfunction and Hypertension
Nadruz, W., Shah, A. M., & Solomon, S. D. (2016) · Medical Clinics of North America · doi:10.1016/j.mcna.2016.08.013 · Cited by 114 · see citing works
Garza, C. A., Pellikka, P. A., Somers, V. K., Sarr, M. G., Collazo–Clavell, M. L., Korenfeld, Y., & López-Jiménez, F. A. (2010) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.09.057 · Cited by 108 · see citing works
Arterial stiffness and coronary artery disease
Ikonomidis, I., Makavos, G., & Lekakis, J. P. (2015) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000179 · Cited by 99 · see citing works
Self-citationIkonomidis, I., Lekakis, J. P., Papadopoulos, C. H., Triantafyllidi, H., PARASKEVAIDIS, I. A., Georgoula, G., Tzortzis, S., Revela, I., & Kremastinos, D. (2008) · American Journal of Hypertension · doi:10.1038/ajh.2008.172 · Cited by 96 · see citing works
Self-citationKokkinos, A., Alexiadou, K., Liaskos, C., Argyrakopoulou, G., Balla, I., Tentolouris, N., Moyssakis, I., Katsilambros, N., Vafiadis, I., Alexandrou, A., et al. (2013) · Obesity Surgery · doi:10.1007/s11695-012-0743-8 · Cited by 90 · see citing works
Urbina, E. M., Dolan, L. M., McCoy, C. E., Khoury, P. R., Daniels, S. R., & Kimball, T. R. (2011) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2010.12.020 · Cited by 86 · see citing works
Cooper, J. N., Buchanich, J. M., Youk, A. O., Brooks, M. M., Barinas‐Mitchell, E., Conroy, M. B., & Sutton-Tyrrell, K. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.05.022 · Cited by 81 · see citing works
Subclinical Myocardial Impairment in Metabolic Diseases
Kosmala, W., Sanders, P., & Marwick, T. H. (2017) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2017.04.001 · Cited by 69 · see citing works
Surgical Management of Obesity and the Relationship to Cardiovascular Disease
Vest, A. R., Heneghan, H., Schauer, P. R., & Young, J. B. (2013) · Circulation · doi:10.1161/circulationaha.112.103275 · Cited by 66 · see citing works
Kindel, T. L., & Strande, J. L. (2017) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2017.09.534 · Cited by 64 · see citing works
Reductions in cardiovascular risk after bariatric surgery
Benraouane, F., & Litwin, S. E. (2011) · Current Opinion in Cardiology · doi:10.1097/hco.0b013e32834b7fc4 · Cited by 63 · see citing works
The Effect of Surgical Weight Reduction on Left Ventricular Structure and Function in Severe Obesity
Hsuan, C., Huang, C., Lin, J., Lin, L., Lee, T., Tai, C., Yin, W., Tseng, W., Hsu, K., & Wu, C. (2010) · Obesity · doi:10.1038/oby.2010.42 · Cited by 61 · see citing works
Kosmala, W., O'Moore‐Sullivan, T. M., Płaksej, R., Przewlocka-Kosmala, M., & Marwick, T. H. (2009) · Diabetologia · doi:10.1007/s00125-009-1507-4 · Cited by 54 · see citing works
The effects of bariatric surgery on cardiac function: a systematic review and meta-analysis
Sargsyan, N., Chen, J. Y., Aggarwal, R., Fadel, M. G., Fehervari, M., & Ashrafian, H. (2023) · International Journal of Obesity · doi:10.1038/s41366-023-01412-3 · Cited by 53 · see citing works
Pouwels, S., Topal, B., Knook, M. T. T., Çelik, A., Sundbom, M., Ribeiro, R. J. D. S., Parmar, C. D., & Ugale, S. M. (2019) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2019.1581064 · Cited by 54 · see citing works
Pontiroli, A. E., Laneri, M., Veronelli, A., Frigè, F., Micheletto, G., Folli, F. B., Adami, G. F., & Scopinaro, N. (2009) · Cardiovascular Diabetology · doi:10.1186/1475-2840-8-37 · Cited by 52 · see citing works
Martin, J., Bergeron, S., Pîbarot, P., Bastien, M., Biertho, L. D., Lescelleur, O., Bertrand, F., Simard, S., & Poirier, P. (2013) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2012.11.010 · Cited by 50 · see citing works
Ikonomidis, I., Tzortzis, S., Papaioannou, T. G., Protogerou, A. D., Stamatelopoulos, K., Papamichael, C. M., Zakopoulos, N. A., & Lekakis, J. (2008) · Journal of Human Hypertension · doi:10.1038/jhh.2008.39 · Cited by 48 · see citing works
Self-citationTriantafyllidi, H., Tzortzis, S., Lekakis, J., Ikonomidis, I., Arvaniti, C., Trivilou, P., Kontsas, K., Siafakas, N., Zerva, L., Stamboulis, E., et al. (2010) · American Journal of Hypertension · doi:10.1038/ajh.2010.156 · Cited by 48 · see citing works
Self-citationKoshino, Y., Villarraga, H. R., Somers, V. K., Miranda, W. R., Garza, C. A., Hsiao, J., Yu, Y., Saleh, H. K., & López-Jiménez, F. A. (2013) · Obesity · doi:10.1002/oby.20168 · Cited by 47 · see citing works
Kaier, T. E., Morgan, D. R., Grapsa, J., Demir, O. M., Paschou, S. Α., Sundar, S., Hakky, S., Purkayastha, S., Connolly, S. L., Fox, K. F., et al. (2014) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeu116 · Cited by 47 · see citing works
From comorbidities to heart failure with preserved ejection fraction: a story of oxidative stress
Franssen, C., Chen, H. S., Hamdani, N., & Paulus, W. J. (2015) · Heart · doi:10.1136/heartjnl-2015-307787 · Cited by 45 · see citing works
The effect of bariatric surgery on echocardiographic indices: a review of the literature
Grapsa, J., Tan, T. C., Paschou, S. Α., Kalogeropoulos, A. S., Shimony, A., Kaier, T. E., Demir, O. M., Mikhail, S., Hakky, S., Purkayastha, S., et al. (2013) · European Journal of Clinical Investigation · doi:10.1111/eci.12162 · Cited by 38 · see citing works
Bariatric surgery to unload the stressed heart: a metabolic hypothesis
Algahim, M. F., Sen, S., & Taegtmeyer, H. (2012) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00626.2011 · Cited by 36 · see citing works
Management of Heart Failure With Preserved Ejection Fraction: A Review
Nanayakkara, S., & Kaye, D. M. (2015) · Clinical Therapeutics · doi:10.1016/j.clinthera.2015.08.005 · Cited by 34 · see citing works
Henry, J. A., Abdesselam, I., Deal, O., Lewis, A., Rayner, J. J., Bernard, M., Dutour, A., Gaborit, B., Kober, F., Soghomonian, A., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1092777 · Cited by 35 · see citing works
Gastrointestinal Surgery for Obesity and Diabetes: Weight Loss and Control of Hyperglycemia
Heneghan, H., Nissen, S. E., & Schauer, P. R. (2012) · Current Atherosclerosis Reports · doi:10.1007/s11883-012-0285-5 · Cited by 34 · see citing works
Pulsatile Hemodynamics and Coronary Artery Disease
Kim, H., & Weber, T. (2021) · Korean Circulation Journal · doi:10.4070/kcj.2021.0227 · Cited by 32 · see citing works
Samaras, K., Viardot, A., Lee, P. N., Jenkins, A. J., Botelho, N. K., Bakopanos, A., Lord, R. V., & Hayward, C. (2012) · Diabetes and Vascular Disease Research · doi:10.1177/1479164112443375 · Cited by 31 · see citing works
Ikonomidis, I., Lambadiari, V., Pavlidis, G., Koukoulis, C., Kousathana, F., Varoudi, M., Spanoudi, F., Maratou, E., Parissis, J., Triantafyllidi, H., et al. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.06.006 · Cited by 30 · see citing works
Self-citationPetersen, K. S., Clifton, P. M., Lister, N. B., & Keogh, J. B. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.01.042 · Cited by 30 · see citing works
Cardiac structure and function before and after bariatric surgery: a clinical overview
Lascaris, B., Pouwels, S., Houthuizen, P., Dekker, L., Nienhuijs, S. W., Bouwman, R. A., & Buise, M. P. (2018) · Clinical Obesity · doi:10.1111/cob.12278 · Cited by 29 · see citing works
Ruiz‐Hurtado, G., García‐Prieto, C. F., Pulido-Olmo, H., Velasco-Martin, J. P., Villa, P., Fernández-Valle, M. E., Boscá, L., Fernández‐Velasco, M., Regadera, J., Somoza, B., et al. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00042 · Cited by 28 · see citing works
Bariatric Surgery and Hypertension
Climent, E., Oliveras, A., Pedro‐Botet, J., Goday, A., & Benaiges, D. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10184049 · Cited by 28 · see citing works
Esparham, A., Shoar, S., Kheradmand, H. R., Ahmadyar, S., Dalili, A., Rezapanah, A., Zandbaf, T., & Khorgami, Z. (2022) · Obesity Surgery · doi:10.1007/s11695-022-06396-z · Cited by 23 · see citing works
Heart failure and cardiac hypertrophy
Rame, J. E., & Dries, D. L. (2007) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-007-0024-3 · Cited by 22 · see citing works
Adams, S. T., Salhab, M., Hussain, Z., Miller, G. V., & Leveson, S. H. (2012) · Blood Pressure · doi:10.3109/08037051.2012.749570 · Cited by 21 · see citing works
Effect of Bariatric Surgery on Cardiovascular Function and Heart Failure Outcomes
Mottel, B. H., Lindsay, D. A., & Frishman, W. H. (2020) · Cardiology in Review · doi:10.1097/crd.0000000000000338 · Cited by 21 · see citing works
Samaras, K., Viardot, A., Botelho, N. K., Jenkins, A. J., & Lord, R. V. (2013) · Diabetologia · doi:10.1007/s00125-013-3033-7 · Cited by 20 · see citing works
Pouwels, S., Lascaris, B., Nienhuijs, S. W., Bouwman, R. A., & Buise, M. P. (2017) · Obesity Surgery · doi:10.1007/s11695-017-2564-2 · Cited by 19 · see citing works
Ebadinejad, A., Barzin, M., Abiri, B., Mahdavi, M., Khalaj, A., Ebrahimi, D., Hosseinpanah, F., & Valizadeh, M. (2022) · BMC Surgery · doi:10.1186/s12893-022-01740-7 · Cited by 18 · see citing works
Yu, H., Chen, J., Lu, J., Bao, Y., Tu, Y., Zhang, L., Zhang, P., & Jia, W. (2015) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2015.09.003 · Cited by 18 · see citing works
Strong, A. T., Sharma, G., Tu, C., Aminian, A., Young, J. B., Rodriguez, J. H., & Kroh, M. (2018) · Obesity Surgery · doi:10.1007/s11695-018-3174-3 · Cited by 17 · see citing works
Pressure Pulse Contour-derived Stroke Volume and Cardiac Output in the Morbidly Obese Patient
Bernstein, D. P. (2008) · Obesity Surgery · doi:10.1007/s11695-007-9378-6 · Cited by 16 · see citing works
Short- and Long-Term Effects of Bariatric Surgery on Vascular Phenotype
Streese, L., Königstein, K., Goricki, L., Infanger, D., Wölnerhanssen, B. K., Peters, T. T. A., Schmidt‐Trucksäss, A., & Hanssen, H. (2019) · Obesity Surgery · doi:10.1007/s11695-018-03679-2 · Cited by 15 · see citing works
Sanches, E. E., Timmermans, M., Topal, B., Çelik, A., Sundbom, M., Ribeiro, R. J. D. S., Parmar, C. D., Ugale, S. M., Proczko, M., Stepaniak, P. S., et al. (2019) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2019.1690991 · Cited by 15 · see citing works
van der Waaij, K. M., Heusinkveld, M. H. G., Delhaas, T., Kroon, A. A., & Reesink, K. D. (2018) · Journal of Hypertension · doi:10.1097/hjh.0000000000001918 · Cited by 14 · see citing works
Stoll, S., Sowah, S. A., Fink, M. A., Nonnenmacher, T., Graf, M. E., Johnson, T., Schlett, C. L., von Stackelberg, O., Kirsten, R., Bamberg, F., et al. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.976949 · Cited by 13 · see citing works
Anesthesia for Bariatric Surgery
Sinha, A. C., & Eckmann, D. M. (2010) · Elsevier eBooks · doi:10.1016/b978-0-443-06959-8.00064-9 · Cited by 12 · see citing works
den Bergh, A. V., Vangheluwe, P., Vanderper, A., Carmeliet, P., Wuytack, F., Janssens, S. P., Flameng, W. J., Holvoet, P., & Herijgers, P. (2009) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfp156 · Cited by 12 · see citing works
Lau, R. G., Kumar, S., Hall, C. E., Palaia, T. A., Rideout, D. A., Hall, K. N., BRATHWAITE, C. E. M., & Ragolia, L. (2015) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2014.12.005 · Cited by 10 · see citing works
Ghanem, S. M., Mostafa, M., & Ayad, S. W. (2010) · Journal of the Saudi Heart Association · doi:10.1016/j.jsha.2010.03.003 · Cited by 10 · see citing works
Sarmiento-Cobos, M. F., Rivera, C. E., Okida, L. F., Cogollo, V. J., Montorfano, L. M., Blanco, D. G., Menzo, E. L., Szomstein, S., & Rosenthal, R. J. (2021) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2021.01.040 · Cited by 10 · see citing works
Bariatric Surgery: Effects on the Metabolic Complications of Obesity
Clifton, P. M. (2012) · Current Atherosclerosis Reports · doi:10.1007/s11883-012-0231-6 · Cited by 10 · see citing works
Improvement of Arterial Stiffness One Month after Bariatric Surgery and Potential Mechanisms
Oliveras, A., Galcerán, I., Goday, A., González, S. V., Sans, L., Riera, M., Benaiges, D., & Pascual, J. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10040691 · Cited by 9 · see citing works
Should We Target Obesity in Advanced Heart Failure?
Vest, A. R., & Young, J. B. (2014) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-013-0284-z · Cited by 8 · see citing works
Bariatric Weight Loss Surgery Improves Systolic Function in Obese Patients With Heart Failure
Balakumaran, K., Jabri, A., Haddadin, F. I., Hamade, H., Lao, N. M., Gaznabi, S., Haddadin, S., Garcia, R. A., Schwab, T. S., Shumiloff, J., et al. (2022) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2022.101231 · Cited by 8 · see citing works
van Heerebeek, L. (2014) · SOJ Pharmacy & Pharmaceutical Sciences · doi:10.15226/2374-6866/1/2/00112 · Cited by 8 · see citing works
Presión arterial central en la obesidad mórbida y tras la cirugía bariátrica
Outón, S., Galcerán, I., Pascual, J., & Oliveras, A. (2019) · Nefrología · doi:10.1016/j.nefro.2019.09.004 · Cited by 8 · see citing works
Rajalakshmi, R., Vageesh, V. Y., & Nataraj, S. M. (2013) · PubMed · Cited by 7 · see citing works
Brathwaite, B. M., Howell, R. S., Petrone, P., & BRATHWAITE, C. E. M. (2021) · The American Surgeon · doi:10.1177/0003134821991975 · Cited by 7 · see citing works
A woman who lost weight at the cost of her heartbeat
Shah, R., Bansal, N., & Manocha, D. (2014) · BMJ Case Reports · doi:10.1136/bcr-2014-205359 · Cited by 5 · see citing works
Central blood pressure in morbid obesity and after bariatric surgery
Outón, S., Galcerán, I., Pascual, J., & Oliveras, A. (2020) · Nefrología (English Edition) · doi:10.1016/j.nefroe.2019.09.003 · Cited by 5 · see citing works
Song, K., Liang, D., Xiao, D., Kang, A., & Ren, Y. (2024) · Molecular Medicine Reports · doi:10.3892/mmr.2024.13323 · Cited by 5 · see citing works
Heart Failure Society of America (2010) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2010.05.015 · Cited by 5 · see citing works
Alencar, A. K. N., Wang, H., de Oliveira, G. M. M., Sun, X., Zapata‐Sudo, G., & Groban, L. (2021) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20200855 · Cited by 5 · see citing works
Vest, A. R. (2018) · Current Heart Failure Reports · doi:10.1007/s11897-018-0390-z · Cited by 4 · see citing works
The Obesity Epidemic and Women’s Health
Mackey, R. H., McTigue, K. M., & Kuller, L. H. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-384978-6.00056-x · Cited by 3 · see citing works
Wadden, T. A., Wolfe, B. M., Millen, B. E., Nonas, C., Pi‐Sunyer, F. X., Stevens, J., Stevens, V. J., Donato, K. A., Hu, F. B., Hubbard, S. M., et al. (2013) · Cited by 3 · see citing works
Vlachopoulos, C. V., & Xaplanteris, P. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801387-8.00026-0 · Cited by 2 · see citing works
Olatunji, L. A., Usman, T., Williams, F., Akintoye, O. O., & Olatunji, V. (2014) · Nigerian Journal of Experimental and Clinical Biosciences · doi:10.4103/2348-0149.144849 · Cited by 2 · see citing works
Boutcher, Y. N. (2016) · InTech eBooks · doi:10.5772/64981 · Cited by 1 · see citing works
Bariatric surgeries and cardiac structure and function: Systematic review and network meta‐analysis
Zhang, X., Chen, K., Zhang, Z., Zhang, N., Zheng, F., Zhou, B., Meng, H., Zhang, Z., & Niu, W. (2024) · Obesity Reviews · doi:10.1111/obr.13843 · Cited by 1 · see citing works
Patoulias, D., Karagiannidis, E., Maragkoudakis, S., Alexanian, I. P., Papadopoulos, C., & Fragakis, N. (2026) · Hellenic Journal of Cardiology · doi:10.1016/j.hjc.2026.08.007 · Cited by 1 · see citing works
Self-citationMartin, J., Bergeron, S., Pîbarot, P., Bastien, M., Biertho, L. D., Lescelleur, O., Bertrand, F., Simard, S., & Poirier, P. (2013) · Cited by 1 · see citing works
49 Cardiovascular Disease in the Bariatric Surgery Patient
Vest, A. R., & Young, J. B. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1637-5_49 · Cited by 1 · see citing works
Bariatric Surgery: Can It Perform Benefits or Risks?
Mostafa, T. A.-H., Abdel-Hameed, A. M., & Ahmed, S. A.-K. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1006090 · Cited by 1 · see citing works
Pouwels, S., Sanches, E. E., Topal, B., & Çelik, A. (2020) · Springer eBooks · doi:10.1007/978-3-030-47336-5_18 · Cited by 1 · see citing works
Modeling heart failure with preserved ejection fraction in rodents: Where do we stand?
Chou, C., & Chin, M. T. (2022) · Frontiers in Drug Discovery · doi:10.3389/fddsv.2022.948407 · Cited by 1 · see citing works
Bagg, W., WHALLEY, G. A., & Doughty, R. N. (2007) · Journal of Hypertension · doi:10.1097/hjh.0b013e328013c5aa · Cited by 1 · see citing works
Obesity and the Obesity Paradox in Heart Failure
Oktay, A. A., Lavie, C. J., & Ventura, H. O. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809657-4.10899-3 · Cited by 1 · see citing works
Baumann, T., & Kotter, E. (2012) · Springer eBooks · doi:10.1007/978-3-642-02411-5_25
- Authors
- Ikonomidis, I., Mazarakis, A., Papadopoulos, C., Patsouras, N., Kalfarentzos, F., Lekakis, J., Kremastinos, D. T., & Alexopoulos, D.
- Affiliations
- National and Kapodistrian University of Athens (GR)
- General University Hospital of Patras (GR)
- Corresponding author
- Ikonomidis, Ignatios
- Venue
- Journal of Hypertension
- Published
- 2007-02
- Volume
- 25
- Issue
- 2
- Pages
- 439-447
- ISSN
- 0263-6352 (ISSN-L)
- OpenAlex
- W1966266926
- Cited by
- 118
- References
- 35
- Citations by year
- 2026: 2 · 2024: 5 · 2023: 3 · 2022: 5 · 2021: 7 · 2020: 3 · 2019: 6 · 2018: 4 · 2017: 8 · 2016: 5 · 2015: 9 · 2014: 10 · 2013: 14 · 2012: 11
- FWCI
- 7.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Keywords
- bariatric surgery, gastric bypass, morbid obesity, weight loss, aortic function, aortic distensibility, aortic stiffness, left ventricular diastolic function, left ventricular hypertrophy, isovolumic relaxation time, long-term follow-up
- MeSH terms
- Adult, Aorta, Aortic Diseases, Cardiovascular Diseases, Echocardiography, Female, Follow-Up Studies, Humans, Male, Middle Aged, Obesity, Morbid, Time, Weight Loss, Ventricular Function, Left, Hypertrophy, Left Ventricular, Bariatric Surgery
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review