Improvement in cardiovascular indices after Roux-en-Y gastric bypass or sleeve gastrectomy for morbid obesity
Abstract
Background Morbidly obese patients display cardiac abnormalities which are partially reversed after weight loss. The aim of the present study was to assess the potential difference in cardiovascular disease indices between patients who underwent either gastric bypass surgery or sleeve gastrectomy.Methods Thirty-seven morbidly obese patients who underwent either Roux-en-Y gastric bypass (RYGB) (n = 14) or SG (n = 23) were examined before, 3 and 6 months after surgery. Indices of cardiac autonomic nervous system activity were evaluated, namely baroreflex sensitivity (BRS) and heart rate variability (HRV). A complete echocardiographic study was performed in a subgroup of 17 patients (RYGB 8, SG 9) preoperatively and 6 months after surgery, evaluating epicardial fat thickness, aortic distensibility, left ventricular (LV) Tei index, left atrium diameter, ejection fraction, and LV mass.Results All subjects experienced significant (p < 0.001) and similar weight loss independently of the type of operation. BRS and HRV indices improved significantly and to the same degree after surgery in both groups. In the echocardiographic study, all parameters improved significantly at 6 months in comparison with the baseline values. In addition, the RYGB group displayed significantly greater reduction in epicardial fat thickness (p = 0.007) and also tended to have a better LV performance as expressed by the lower values of the Tei index (p = 0.06) compared to the SG group 6 months after surgery.Conclusions Both RYGB and SG exert comparable effects on weight loss and improvement of cardiovascular parameters. RYGB displays a more beneficial influence on epicardial fat thickness and left ventricular performance than SG.
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Roux-en-Y procedure produces greater reduction in EAT than sleeve gastroplasty, despite similar weight loss or reduction in waist circumference.
“Kokkinos et al. report a greater reduction in EAT with Roux-en-Y procedure than sleeve gastroplasty, despite similar weight loss or reduction in waist circumference [144].”
From Dysregulated epicardial adipose tissue as a risk factor and potential therapeutic target of heart failure with preserved ejection fraction in diabetes (2022) · cites this paper as [144]
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- Authors
- Kokkinos, A., Alexiadou, K., Liaskos, C., Argyrakopoulou, G., Balla, I., Tentolouris, N., Moyssakis, I., Katsilambros, N., Vafiadis, I., Alexandrou, A., & Diamantis, T.
- Affiliations
- Laiko General Hospital of Athens (GR)
- Venue
- Obesity Surgery
- Published
- 2012-08-25
- Volume
- 23
- Issue
- 1
- Pages
- 31-38
- ISSN
- 0960-8923 (ISSN-L)
- 1708-0428
- OpenAlex
- W2066498088
- Cited by
- 90
- References
- 59
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 10 · 2023: 7 · 2022: 10 · 2021: 7 · 2020: 8 · 2019: 9 · 2018: 8 · 2017: 8 · 2016: 5 · 2015: 8 · 2014: 4 · 2013: 3
- FWCI
- 4.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Obesity Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Keywords
- Roux-en-Y gastric bypass, sleeve gastrectomy
- MeSH terms
- Adult, Cardiovascular Diseases, Female, Follow-Up Studies, Humans, Male, Obesity, Morbid, Laparoscopy, Prospective Studies, Stroke Volume, Gastric Bypass, Gastroplasty, Weight Loss, Body Mass Index, Ventricular Function, Left, Treatment Outcome, Baroreflex, Intra-Abdominal Fat
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