Cited by 90Bariatric Surgery and OutcomesCardiovascular Function and Risk FactorsCardiovascular Disease and Adiposity

Improvement in cardiovascular indices after Roux-en-Y gastric bypass or sleeve gastrectomy for morbid obesity

Kokkinos, Alexander, Alexiadou, Kleopatra, Liaskos, Christos, Argyrakopoulou, Georgia, Balla, Ioanna, Tentolouris, Nicholas, Moyssakis, Ioannis, Katsilambros, Nicholas +3 more·2013·Obesity Surgery

Abstract

Background Morbidly obese patients display cardiac abnormalities which are partially reversed after weight loss. The aim of the present study was to assess the potential difference in cardiovascular disease indices between patients who underwent either gastric bypass surgery or sleeve gastrectomy.Methods Thirty-seven morbidly obese patients who underwent either Roux-en-Y gastric bypass (RYGB) (n = 14) or SG (n = 23) were examined before, 3 and 6 months after surgery. Indices of cardiac autonomic nervous system activity were evaluated, namely baroreflex sensitivity (BRS) and heart rate variability (HRV). A complete echocardiographic study was performed in a subgroup of 17 patients (RYGB 8, SG 9) preoperatively and 6 months after surgery, evaluating epicardial fat thickness, aortic distensibility, left ventricular (LV) Tei index, left atrium diameter, ejection fraction, and LV mass.Results All subjects experienced significant (p < 0.001) and similar weight loss independently of the type of operation. BRS and HRV indices improved significantly and to the same degree after surgery in both groups. In the echocardiographic study, all parameters improved significantly at 6 months in comparison with the baseline values. In addition, the RYGB group displayed significantly greater reduction in epicardial fat thickness (p = 0.007) and also tended to have a better LV performance as expressed by the lower values of the Tei index (p = 0.06) compared to the SG group 6 months after surgery.Conclusions Both RYGB and SG exert comparable effects on weight loss and improvement of cardiovascular parameters. RYGB displays a more beneficial influence on epicardial fat thickness and left ventricular performance than SG.

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Crossref · 10.1007/s11695-012-0743-8

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Authors
Kokkinos, A., Alexiadou, K., Liaskos, C., Argyrakopoulou, G., Balla, I., Tentolouris, N., Moyssakis, I., Katsilambros, N., Vafiadis, I., Alexandrou, A., & Diamantis, T.
Affiliations
Laiko General Hospital of Athens (GR)
Venue
Obesity Surgery
Published
2012-08-25
Volume
23
Issue
1
Pages
31-38
ISSN
  • 0960-8923 (ISSN-L)
  • 1708-0428
OpenAlex
W2066498088
Cited by
90
References
59
Citations by year
2026: 2 · 2025: 1 · 2024: 10 · 2023: 7 · 2022: 10 · 2021: 7 · 2020: 8 · 2019: 9 · 2018: 8 · 2017: 8 · 2016: 5 · 2015: 8 · 2014: 4 · 2013: 3
FWCI
4.89
Type
journal article
Language
en
Open access
closed
Locations
  • Obesity Surgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
Keywords
Roux-en-Y gastric bypass, sleeve gastrectomy
MeSH terms
Adult, Cardiovascular Diseases, Female, Follow-Up Studies, Humans, Male, Obesity, Morbid, Laparoscopy, Prospective Studies, Stroke Volume, Gastric Bypass, Gastroplasty, Weight Loss, Body Mass Index, Ventricular Function, Left, Treatment Outcome, Baroreflex, Intra-Abdominal Fat

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