Cited by 261Blood Pressure and Hypertension StudiesCardiovascular Health and Disease PreventionCardiovascular Function and Risk Factors

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Home versus ambulatory and office blood pressure in predicting target organ damage in hypertension: a systematic review and meta-analysis

Bliziotis, Ioannis A., Destounis, Antonis, Stergiou, George S.·2012·Journal of Hypertension

DOI 10.1097/hjh.0b013e3283531eaf

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Abstract

OBJECTIVE: Studies have shown that ambulatory blood pressure (BP) is more closely related to preclinical target organ damage than office measurements. A review and meta-analysis of studies investigating the association of home BP measurements with target organ damage was performed. METHODS: A PubMed and Cochrane Library search (1950-2011) revealed 23 studies reporting comparative data of home BP versus ambulatory and/or office measurements in terms of their association with several indices of target organ damage. Correlation coefficients were pooled by random-effects model meta-analysis. RESULTS: Fourteen studies (n = 2485) assessing echocardiographic left ventricular mass index (LVMI) showed similar correlations with home (coefficients r = 0.46/0.28, systolic/diastolic) as with ambulatory BP (0.37/0.26, P = NS for difference versus home BP), and superior to office measurements (r = 0.23/0.19, P < 0.001/0.009 for difference versus home BP). Four methodologically heterogeneous studies assessing the glomerular filtration rate (n = 609) could not be pooled or lead to a concrete result. Four studies assessing carotid intima-media thickness (n = 1222), three assessing pulse wave velocity (n = 720) and two assessing urinary protein excretion (n = 156) showed no difference in pooled correlation coefficients with home versus office BP measurements. With all the measurement methods SBP was more closely associated with target organ damage than DBP. CONCLUSION: These data suggest that home BP is as good as ambulatory monitoring and superior to office measurements in regard to their association with preclinical organ damage assessed by echocardiographic LVMI. More research is required to evaluate the relationship of home BP with other indices of target organ damage.

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Authors: Bliziotis, I. A., Destounis, A., & Stergiou, G. S.
Affiliations: Sotiria General Hospital (GR)
Corresponding author: Stergiou, George S.
ORCID: Stergiou, George S.
Venue: Journal of Hypertension
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2012-07
Volume: 30
Issue: 7
Pages: 1289-1299
ISSN: 0263-6352 (ISSN-L)
DOI: 10.1097/hjh.0b013e3283531eaf
OpenAlex: W2000311463
Cited by: 261
References: 43
Citations by year: 2026: 7 · 2025: 8 · 2024: 11 · 2023: 14 · 2022: 26 · 2021: 22 · 2020: 21 · 2019: 22 · 2018: 25 · 2017: 24 · 2016: 21 · 2015: 22 · 2014: 20 · 2013: 15 · 2012: 3
FWCI: 3.15
Type: journal article
Language: en
Open access: closed
Locations: Journal of Hypertension (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
Keywords: home blood pressure, ambulatory blood pressure, office blood pressure, target organ damage, hypertension, left ventricular mass index, glomerular filtration rate, carotid intima-media thickness, pulse wave velocity, urinary protein excretion, ambulatory blood pressure monitoring
MeSH terms: Blood Pressure, Echocardiography, Glomerular Filtration Rate, Heart Ventricles, Humans, Hypertension, Proteinuria, Self Care, Blood Pressure Monitoring, Ambulatory

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Home versus ambulatory and office blood pressure in predicting target organ damage in hypertension: a systematic review and meta-analysis

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