The impact of sprint interval training versus moderate intensity continuous training on blood pressure and cardiorespiratory health in adults: a systematic review and meta-analysis
Open accessAbstract
Background Although aerobic exercise is the primary modality recommended for the treatment of hypertension, it remains unclear whether high-intensity all-out sprint interval training (SIT) can result in greater reductions of blood pressure (BP) and cardiorespiratory health. This systematic review aims to compare the impact of SITversusModerate-intensity continuous training (MICT) on improvements in resting systolic blood pressure (SBP), diastolic blood pressure (DBP) and maximal oxygen uptake (VO2max) among adults. Methods We conducted a systematic search of three online databases (PubMed, Embase, and Web of Science) from January 2000 to July 2023 to identify randomized controlled trials that compared the chronic effects of SITversusMICT on BP in participants with high or normal blood pressure. We extracted information on participant characteristics, exercise protocols, BP outcomes, and intervention settings. Furthermore, the changes in VO2max between the two groups were analyzed using a meta-analysis. The pooled results were presented as weighted means with 95% confidence intervals (CI). Results Out of the 1,874 studies initially were found, eight were included in this review, totaling 169 participants. A significant decrease in SBP (MD = −2.82 mmHg, 95% CI [−4.53 to −1.10],p = 0.08,I2=45%) was observed in the SIT group compared to before the training, but no significant decrease in DBP (MD = −0.75 mmHg, 95% CI [−1.92 to 0.42],p = 0.16,I2= 33%) was observed. In contrast, both SBP (MD = −3.00 mmHg, 95% CI [−5.31 to −0.69],p = 0.68,I2= 0%) and DBP (MD = −2.11 mmHg, 95% CI [−3.63 to −0.60],p = 0.72,I2= 0%) significantly decreased in the MICT group with low heterogeneity. No significant difference was found in resting SBP and DBP between SIT and MICT after the intervention. Both SIT and MICT significantly increased VO2peak, with SIT resulting in a mean difference (MD) of 1.75 mL/kg/min (95% CI [0.39–3.10],p = 0.02,I2= 61%), and MICT resulting in a mean difference of 3.10 mL/kg/min (95% CI [1.03–5.18],p = 0.007,I2= 69%). MICT was more effective in improving VO2peak (MD = −1.36 mL/kg/min, 95% CI [−2.31 to 0.40],p = 0.56,I2= 0%). Subgroup analysis of duration and single sprint time showed that SIT was more effective in reducing SBP when the duration was ≥8 weeks or when the sprint time was <30 s. Conclusion Our meta-analysis showed that SIT is an effective intervention in reducing BP and improving cardiorespiratory fitness among adults. Consequently, SIT can be used in combination with traditional MICT to increase the variety, utility, and time efficiency of exercise prescriptions for different populations.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139 · see citing works
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552 · see citing works
(2014) · Medical Entomology and Zoology · Cited by 9,400 · see citing works
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000065 · Cited by 7,391 · see citing works
Guthold, R., Stevens, G. A., Riley, L. M., & Bull, F. C. (2018) · The Lancet Global Health · doi:10.1016/s2214-109x(18)30357-7 · Cited by 4,819 · see citing works
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000066 · Cited by 4,347 · see citing works
Mills, K. T., Bundy, J. D., Kelly, T. N., Reed, J. E., Kearney, P. M., Reynolds, K., Chen, J., & He, J. (2016) · Circulation · doi:10.1161/circulationaha.115.018912 · Cited by 3,531 · see citing works
Kodama, S. (2009) · JAMA · doi:10.1001/jama.2009.681 · Cited by 3,035 · see citing works
Ross, R., Blair, S. N., Arena, R., Church, T. S., Després, J.-P., Franklin, B. A., Haskell, W. L., Kaminsky, L. A., Levine, B. D., Lavie, C. J., et al. (2016) · Circulation · doi:10.1161/cir.0000000000000461 · Cited by 2,486 · see citing works
Physiological adaptations to low-volume, high-intensity interval training in health and disease
Gibala, M. J., Little, J. P., MacDonald, M. J., & Hawley, J. A. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2011.224725 · Cited by 1,744 · see citing works
Exercise Training for Blood Pressure: A Systematic Review and Meta‐analysis
Cornelissen, V. A., & Smart, N. A. (2013) · Journal of the American Heart Association · doi:10.1161/jaha.112.004473 · Cited by 1,683 · see citing works
Rapsomaniki, E., Timmis, A., George, J., Pujades-Rodriguez, M., Shah, A. D., Denaxas, S., White, I. R., Caulfield, M. J., Deanfield, J. E., Smeeth, L., et al. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60685-1 · Cited by 1,643 · see citing works
Buchheit, M., & Laursen, P. B. (2013) · Sports Medicine · doi:10.1007/s40279-013-0029-x · Cited by 1,490 · see citing works
Tjønna, A. E., Lee, S. J., Rognmo, Ø., Stølen, T. O., Bye, A., Haram, P. M., Loennechen, J. P., Al-Share, Q. Y., Skogvoll, E., Slørdahl, S. A., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.772822 · Cited by 1,145 · see citing works
Physiological adaptations to interval training and the role of exercise intensity
MacInnis, M. J., & Gibala, M. J. (2017) · The Journal of Physiology · doi:10.1113/jp273196 · Cited by 1,124 · see citing works
Gibala, M. J., Little, J. P., Van Essen, M., Wilkin, G. P., Burgomaster, K. A., Safdar, A., Raha, S., & Tarnopolsky, M. A. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.112094 · Cited by 1,082 · see citing works
Progress in physical activity over the Olympic quadrennium
Sallis, J. F., Bull, F., Guthold, R., Heath, G. W., Inoue, S., Kelly, P., Oyeyemi, A. L., Perez, L. G., Richards, J., & Hallal, P. C. (2016) · The Lancet · doi:10.1016/s0140-6736(16)30581-5 · Cited by 935 · see citing works
Burgomaster, K. A., Hughes, S. C., Heigenhauser, G. J. F., Bradwel, S. N., & Gibala, M. J. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01095.2004 · Cited by 856 · see citing works
Jelleyman, C., Yates, T., O'Donovan, G., Gray, L. J., King, J. A., Khunti, K., & Davies, M. J. (2015) · Obesity Reviews · doi:10.1111/obr.12317 · Cited by 588 · see citing works
Rabi, D. M., McBrien, K. A., Sapir-Pichhadze, R., Nakhla, M., Ahmed, S. B., Dumanski, S. M., Butalia, S., Leung, A. A., Harris, K. C., Cloutier, L., et al. (2020) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2020.02.086 · Cited by 583 · see citing works
Lee, D.-C., Sui, X., Artero, E. G., Lee, I.-M., Church, T. S., McAuley, P. A., Stanford, F. C., Kohl, H. W., & Blair, S. N. (2011) · Circulation · doi:10.1161/circulationaha.111.038422 · Cited by 572 · see citing works
The Potential for High-Intensity Interval Training to Reduce Cardiometabolic Disease Risk
Kessler, H. S., Sisson, S. B., & Short, K. R. (2012) · Sports Medicine · doi:10.2165/11630910-000000000-00000 · Cited by 461 · see citing works
Weston, M., Taylor, K. L., Batterham, A. M., & Hopkins, W. G. (2014) · Sports Medicine · doi:10.1007/s40279-014-0180-z · Cited by 407 · see citing works
Keating, S. E., Johnson, N. A., Mielke, G. I., & Coombes, J. S. (2017) · Obesity Reviews · doi:10.1111/obr.12536 · Cited by 344 · see citing works
Rakobowchuk, M., Tanguay, S., Burgomaster, K. A., Howarth, K. R., Gibala, M. J., & MacDonald, M. J. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00069.2008 · Cited by 335 · see citing works
Sprint Interval Training Effects on Aerobic Capacity: A Systematic Review and Meta-Analysis
Gist, N. H., Fedewa, M. V., Dishman, R. K., & Cureton, K. J. (2013) · Sports Medicine · doi:10.1007/s40279-013-0115-0 · Cited by 332 · see citing works
Piper, M., Evans, C. V., Burda, B., Margolis, K., O'Connor, E. A., & Whitlock, E. (2015) · Annals of Internal Medicine · doi:10.7326/m14-1539 · Cited by 330 · see citing works
Moholdt, T. T., Amundsen, B. H., Rustad, L. A., Wahba, A., Lovo, K. T., Gullikstad, L. R., Bye, A., Skogvoll, E., Wisløff, U., & Slørdahl, S. A. (2009) · American Heart Journal · doi:10.1016/j.ahj.2009.10.003 · Cited by 307 · see citing works
The affective beneficence of vigorous exercise revisited
Hall, E. E., Panteleimon Ekkekakis, A., & Petruzzello, S. J. (2002) · British Journal of Health Psychology · doi:10.1348/135910702169358 · Cited by 264 · see citing works
Bliziotis, I. A., Destounis, A., & Stergiou, G. S. (2012) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283531eaf · Cited by 261 · see citing works
Ciolac, E. G., Bocchi, E. A., Bortolotto, L. A., Carvalho, V. O., Greve, J. M. D., & Guimarães, G. V. (2010) · Hypertension Research · doi:10.1038/hr.2010.72 · Cited by 242 · see citing works
Cocks, M., Shaw, C. S., Shepherd, S. O., Fisher, J. P., Ranasinghe, A. M., Barker, T. A., Tipton, K. D., & Wagenmakers, A. J. M. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2012.239566 · Cited by 226 · see citing works
Zhang, H., Tong, T. K., Qiu, W., Zhang, X., Zhou, S., Liu, Y., & He, Y. (2017) · Journal of Diabetes Research · doi:10.1155/2017/5071740 · Cited by 201 · see citing works
ACSM's metabolic Calculations Handbook
GLASS, S. C., & Dwyer, G. (2006) · Cited by 163 · see citing works
Scribbans, T. D., Vecsey, S. P., Hankinson, P. B., Foster, W. S., & Gurd, B. J. (2016) · International journal of exercise science · doi:10.70252/hhbr9374 · Cited by 139 · see citing works
Cochran, A. J. R., Percival, M. E., Tricarico, S., Little, J. P., Cermak, N. M., Gillen, J. B., Tarnopolsky, M. A., & Gibala, M. J. (2014) · Experimental Physiology · doi:10.1113/expphysiol.2013.077453 · Cited by 122 · see citing works
Way, K. L., Sultana, R. N., Sabag, A., Baker, M. K., & Johnson, N. A. (2018) · Journal of science and medicine in sport · doi:10.1016/j.jsams.2018.09.228 · Cited by 122 · see citing works
Pan, H., Hibino, M., Kobeissi, E., & Aune, D. (2019) · European Journal of Epidemiology · doi:10.1007/s10654-019-00593-4 · Cited by 121 · see citing works
Cocks, M., Shaw, C. S., Shepherd, S. O., Fisher, J. P., Ranasinghe, A., Barker, T. A., & Wagenmakers, A. J. M. (2016) · The Journal of Physiology · doi:10.1113/jphysiol.2014.285254 · Cited by 117 · see citing works
Effect of Number of Sprints in an SIT Session on Change in V˙O2max
Vollaard, N. B. J., Metcalfe, R. S., & Williams, S. (2017) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001204 · Cited by 110 · see citing works
Cao, L., Li, X., Yan, P., Wang, X., Li, M., Li, R., Shi, X., Liu, X., & Yang, K. (2019) · Journal of Clinical Hypertension · doi:10.1111/jch.13583 · Cited by 103 · see citing works
Boer, P., Meeus, M., Terblanche, E., Rombaut, L., Wandele, I. D., Hermans, L., Gysel, T., Ruige, J. B., & Calders, P. (2013) · Clinical Rehabilitation · doi:10.1177/0269215513498609 · Cited by 97 · see citing works
Incidence of nonresponse and individual patterns of response following sprint interval training
Gurd, B. J., Giles, M. D., Bonafiglia, J. T., Raleigh, J. P., Boyd, J. C., Ma, J. K., Zelt, J. G. E., & Scribbans, T. D. (2016) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2015-0449 · Cited by 92 · see citing works
Skleryk, J. R., Karagounis, L. G., Hawley, J. A., Sharman, M. J., Laursen, P. B., & Watson, G. (2013) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12150 · Cited by 63 · see citing works
Cuddy, T. F., Ramos, J. S., & Dalleck, L. C. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16030483 · Cited by 57 · see citing works
Igarashi, Y., Akazawa, N., & Maeda, S. (2017) · Clinical and Experimental Hypertension · doi:10.1080/10641963.2017.1384483 · Cited by 56 · see citing works
Lora-Pozo, I., Lucena-Antón, D., Salazar, A., Galán-Mercant, A., & Moral-Muñoz, J. A. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16224524 · Cited by 55 · see citing works
Shenouda, N., Gillen, J. B., Gibala, M. J., & MacDonald, M. J. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00058.2017 · Cited by 53 · see citing works
Naves, J. P. A., Viana, R. B., Rebelo, A. C. S., de Lira, C. A. B., Pimentel, G. D., Lobo, P. C. B., de Oliveira, J. C., Ramírez‐Campillo, R., & Gentil, P. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01738 · Cited by 52 · see citing works
De Smet, S., Van Thienen, R., Deldicque, L., James, R., Sale, C., Bishop, D. J., & Hespel, P. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00233 · Cited by 39 · see citing works
Petrick, H. L., King, T. J., Pignanelli, C., VANDERLINDE, T. E., Cohen, J. N., Holloway, G. P., & Burr, J. F. (2020) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002582 · Cited by 31 · see citing works
Eskelinen, J., HEINONEN, I. H. A., Löyttyniemi, E., Hakala, J. O., Heiskanen, M. A., Motiani, K. K., Virtanen, K. A., Pärkkä, J. P., Knuuti, J. M., Hannukainen, J. C., et al. (2016) · The Journal of Physiology · doi:10.1113/jp273089 · Cited by 29 · see citing works
Fardman, A., Banschick, G. D., Rabia, R., Percik, R., Segev, S., Klempfner, R., Grossman, E., & Maor, E. (2020) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2020.05.017 · Cited by 28 · see citing works
Schneider, R. H., Salerno, J. W., & Brook, R. D. (2020) · Journal of Hypertension · doi:10.1097/hjh.0000000000002625 · Cited by 27 · see citing works
Hazell, T. J., Olver, T. D., MacPherson, R. E. K., Hamilton, C. D., & Lemon, P. W. R. (2014) · PubMed · Cited by 17 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Zheng, W., Yin, M., Guo, Y., Liu, H., Sun, J., Zhu, A., Zhong, Y., Xu, K., Li, H., & Piao, S.-Z. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1625516 · Cited by 13 · see citing works
Wang, Q., Wu, D., & Huang, Y. T. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1682814 · Cited by 10 · see citing works
Hu, M., Chen, X., Nie, J., Shi, Q., & Kong, Z. (2025) · Journal of Exercise Science & Fitness · doi:10.1016/j.jesf.2025.06.006 · Cited by 5 · see citing works
Huang, G., Chen, Y., Lee, B.-C., Qiu, Y., Mao, A., Liang, M., & Liu, M. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1555019 · Cited by 6 · see citing works
Li, Q., Liu, Q., Zhong, L., Lin, W., Huang, F., & Zhu, P. (2024) · Open Life Sciences · doi:10.1515/biol-2022-0959 · Cited by 3 · see citing works
Li, A., Li, H., & Chen, J. (2025) · Journal of Exercise Science & Fitness · doi:10.1016/j.jesf.2025.04.004 · Cited by 2 · see citing works
Liang, W., Zhu, H., Zhao, L., Yan, X., Lyu, Z., Liu, C., & Huang, W. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2025.1708893 · Cited by 2 · see citing works
Self-citationFeng, Y., Li, D., Liu, Y., & Tang, D. (2025) · Journal of Human Kinetics · doi:10.5114/jhk/205427 · Cited by 3 · see citing works
“Our meta ‐ analysis found that MICT had a greater effect on peak oxygen uptake than HIIT, which is consistent with a recent review of related studies (Guo et al., 2022; Liang et al., 2024).”
Liang, W., Wang, Y., Yu, T., Hou, Y., Xu, S., Lyu, Z., Zhang, Y., & Huang, W. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2025.1703829 · Cited by 1 · see citing works
Self-citationLin, H.-W., Chang, Y.-C., Hsu, T.-H., & Lin, Y.-N. (2026) · Frontiers in Neurology · doi:10.3389/fneur.2026.1727980 · Cited by 1 · see citing works
Liang, W., Liu, C., Xu, S., Ma, S., Zong, Y., & Yan, X. (2025) · European Journal of Applied Physiology · doi:10.1007/s00421-025-05975-z
Self-citationA HOLISTIC APPROACH TO LOWERING BLOOD PRESSURE
Gawron, J., Grajcarek, Ł., Hamerla, A., Szydłowski, R., Bodera, M., Porwolik, H., Porwolik, A., Czarnecki, B., Kaźmierska, A., & Tadeusiak, B. (2026) · International Journal of Innovative Technologies in Social Science · doi:10.31435/ijitss.1(49).2026.4682
- Authors
- Liang, W., Liu, C., Yan, X., Hou, Y., Yang, G., Dai, J., & Wang, S.
- Affiliations
- South China Normal University (CN)
- Kunsan National University (KR)
- South China University of Technology (CN)
- Kyungnam University (KR)
- Corresponding author
- Wang, Songtao
- Venue
- PeerJ
- Publisher
- PeerJ
- Published
- 2024-03-14
- Volume
- 12
- Pages
- e17064
- ISSN
- 2167-8359 (ISSN-L)
- PMC
- PMC10944631
- OpenAlex
- W4392811671
- Cited by
- 12
- References
- 55
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 1
- FWCI
- 1.24
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PeerJ (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Keywords
- sprint interval training, moderate-intensity continuous training, blood pressure, hypertension, systolic blood pressure, diastolic blood pressure, cardiorespiratory fitness, VO2max, peak oxygen uptake, high-intensity interval training, aerobic exercise, exercise training comparison, adults, blood pressure reduction, exercise frequency
- MeSH terms
- High-Intensity Interval Training, Adult, Blood Pressure, Exercise Therapy, Humans, Hypertension, Hypotension, Exercise
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review