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Cited by 107Personality Disorders and PsychopathologyBipolar Disorder and TreatmentChild and Adolescent Psychosocial and Emotional Development

The DOI matches its Crossref record; 136 of the 136 references it cites were found in a registry or an index.

Integrating Early Intervention for Borderline Personality Disorder and Mood Disorders

Open access
Chanen, Andrew M., Berk, Michael, Thompson, Katherine·2016·Harvard Review of Psychiatry
DOI 10.1097/hrp.0000000000000105
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Abstract

Borderline personality disorder (BPD) has been demonstrated to be a reliable and valid construct in young people (adolescents and young adults). Both borderline- and mood-related psychopathology become clinically apparent from puberty through to young adulthood, frequently co-occur, can reinforce one another, and can be difficult to differentiate clinically. This Gordian knot of overlapping clinical features, common risk factors, and precursors to both BPD and mood disorders complicates clinical assessment, prevention, and treatment. Regardless of whether an individual crosses an arbitrary diagnostic threshold, a considerable proportion of young people with borderline- and mood-related psychopathology will develop significant and persistent functional, vocational, and interpersonal impairment and disability during this critical risk and developmental period. There is a clear need for early intervention, but spurious diagnostic certainty risks stigma, misapplication of diagnostic labels, inappropriate treatment, and unfavorable outcomes. This article aims to integrate early intervention for BPD and mood disorders in the clinical context of developmental and phenomenological change and evolution. “Clinical staging,” similar to disease staging in general medicine, is presented as a pragmatic, heuristic, and trans-diagnostic framework to guide prevention and intervention. It acknowledges that the early stages of these disorders cannot be disentangled sufficiently to allow for disorder-specific preventive measures and early interventions. Clinical staging defines an individual’s location along the continuum of the evolving temporal course of a disorder. Such staging aids differentiation of early or milder clinical phenomena from those that accompany illness progression and chronicity, and suggests the application of appropriate and proportionate intervention strategies.

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Crossref · 10.1097/hrp.0000000000000105

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136 of 136 references verified0 citation errors · 0 not checkable

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Citations

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  1. 2013, Personality disorders begin in adolescence, J Can Acad Child Adolesc Psychiatry, 22, 195

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Metadata

Authors
Chanen, A. M., Berk, M., & Thompson, K.
Affiliations
Deakin University (AU)
Corresponding author
Chanen, Andrew M.
ORCID
Venue
Harvard Review of Psychiatry
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2016-09
Volume
24
Issue
5
Pages
330-341
ISSN
  • 1067-3229 (ISSN-L)
  • 1465-7309
DOI
10.1097/hrp.0000000000000105
OpenAlex
W2346218050
Cited by
107
References
136
Citations by year
2026: 4 · 2025: 14 · 2024: 11 · 2023: 13 · 2022: 11 · 2021: 18 · 2020: 15 · 2019: 6 · 2018: 9 · 2017: 3 · 2016: 3
FWCI
1.04
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Harvard Review of Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • Figshare (submittedVersion, cc-by)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords
borderline personality disorder, mood disorders, early intervention, clinical staging, adolescents, young adults, comorbidities, diagnostic uncertainty, prevention, functional disability
MeSH terms
Bipolar Disorder, Borderline Personality Disorder, Depressive Disorder, Major, Major Depressive Disorder, Humans, Comorbidity, Early Medical Intervention

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