Nocturnal Gastroesophageal Reflux Disease (GERD) and Sleep: An Important Relationship That Is Commonly Overlooked
Abstract
Gastroesophageal reflux disease (GERD) is a prevalent, chronic medical condition that affects 13% of the adult population globally at least once a week. Sleep disturbances are frequently encountered in up to 25% of the GERD patients, likely due to nocturnal gastroesophageal reflux (GER). With advance in diagnostic techniques allowing for an improved understanding of involved physiological mechanisms of nocturnal reflux, there is growing evidence of a bidirectional relationship between GERD and sleep disturbances. Furthermore, nocturnal GER is associated with more complicated GERD. Obstructive sleep apnea (OSA) and GERD also have been linked, but to what degree remains controversial. Treatment of nocturnal GER has been shown to improve both subjective and objective sleep measures. The therapeutic approach includes lifestyle modifications and medication individualization and optimization with proton-pump inhibitors serving as the mainstay of treatment. Antireflux surgery and newer endoscopic procedures have been demonstrated to control nocturnal GER.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Higher carbohydrate intake in teenage females is correlated with decreased total sleep.
“Recent correlations between higher carbohydrate intake in teenage females and decreased total sleep, suggest prioritizing fats or proteins pre-sleep may be more beneficial to sleep duration [263].”
From International society of sports nutrition position stand: nutritional concerns of the female athlete (2023) · cites this paper as [263]
Cites
Vakil, N. B., van Zanten, S. V., Kahrilas, P. J., Dent, J., Jones, R. H., & the Global Consensus Group (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00630.x · Cited by 3,938 · see citing works
Ohayon, M. M., Carskadon, M. A., Guilleminault, C., & Vitiello, M. V. (2004) · Sleep · doi:10.1093/sleep/27.7.1255 · Cited by 3,349 · see citing works
Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma
Lagergren, J., Bergström, R., Lindgren, A., & Nyrén, O. (1999) · New England Journal of Medicine · doi:10.1056/nejm199903183401101 · Cited by 3,012 · see citing works
Chronic Obstructive Pulmonary Disease
Flavin, K., Morkane, C. M., & Marsh, S. (2018) · Cambridge University Press eBooks · doi:10.1017/9781108233712.025 · Cited by 2,694 · see citing works
Locke, G. R., Talley, N. J., Fett, S. L., ZINSMEISTER, A. R., & Melton, L. J. (1997) · Gastroenterology · doi:10.1016/s0016-5085(97)70025-8 · Cited by 2,090 · see citing works
Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review
El‐Serag, H. B., Sweet, S., Winchester, C., & Dent, J. (2013) · Gut · doi:10.1136/gutjnl-2012-304269 · Cited by 1,934 · see citing works
Peery, A. F., Crockett, S. D., Murphy, C. C., Lund, J. L., Dellon, E. S., Williams, J. L., Jensen, E. T., Shaheen, N. J., Barritt, A. S., Lieber, S. R., et al. (2019) · Gastroenterology · doi:10.1053/j.gastro.2018.08.063 · Cited by 1,619 · see citing works
AASM Scoring Manual Updates for 2017 (Version 2.4)
Berry, R. B., Brooks, R., Gamaldo, C. E., Harding, S. M., Lloyd, R. M., Quan, S. F., Troester, M. M., & Vaughn, B. V. (2017) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.6576 · Cited by 1,605 · see citing works
Risk Factors for Obstructive Sleep Apnea in Adults
Young, T. (2004) · JAMA · doi:10.1001/jama.291.16.2013 · Cited by 1,216 · see citing works
St-Onge, M.-P., Grandner, M. A., Brown, D., Conroy, M. B., Jean-Louis, G., Coons, M., & Bhatt, D. L. (2016) · Circulation · doi:10.1161/cir.0000000000000444 · Cited by 1,044 · see citing works
Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects.
Dent, J., Dodds, W. J., Friedman, R. H., et al. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109667 · Cited by 934 · see citing works
Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis
Eusebi, L. H., Ratnakumaran, R., Yuan, Y., Solaymani–Dodaran, M., Bazzoli, F., & Ford, A. C. (2017) · Gut · doi:10.1136/gutjnl-2016-313589 · Cited by 799 · see citing works
Patterns of Gastroesophageal Reflux in Health and Disease
DeMeester, T. R., Johnson, L. F., JOSEPH, G. J., et al. (1976) · Annals of Surgery · doi:10.1097/00000658-197610000-00009 · Cited by 726 · see citing works
Time Trends of Gastroesophageal Reflux Disease: A Systematic Review
El‐Serag, H. B. (2006) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2006.09.016 · Cited by 432 · see citing works
Shaker, R., Castell, D. O., Schoenfeld, P., & Spechler, S. J. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07531.x · Cited by 418 · see citing works
Non‐erosive reflux disease (NERD) — acid reflux and symptom patterns
Martinez, S. D., Malagon, I. B., Garewal, H. S., Cui, H., & Fass, R. (2003) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01423.x · Cited by 396 · see citing works
Self-citationCamilleri, M., Dubois, D., Coulie, B. J., Jones, M., Kahrilas, P. J., Rentz, A. M., Sonnenberg, A., Stanghellini, V., Stewart, W. F., Tack, J. F., et al. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(05)00153-9 · Cited by 382 · see citing works
Circadian variation in gastric emptying of meals in humans
Goo, R. H., Moore, J. G., Greenberg, E., & Alazraki, N. P. (1987) · Gastroenterology · doi:10.1016/0016-5085(87)90913-9 · Cited by 345 · see citing works
Management of Gastroesophageal Reflux Disease
Gyawali, C. P., & Fass, R. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.07.049 · Cited by 345 · see citing works
Self-citationLong-term effect of H2RA therapy on nocturnal gastric acid breakthrough
Fackler, W. K., Ours, T. M., Vaezi, M. F., & Richter, J. E. (2002) · Gastroenterology · doi:10.1053/gast.2002.31876 · Cited by 330 · see citing works
Farup, C. E., Kleinman, L., Sloan, S., et al. (2001) · Archives of Internal Medicine · doi:10.1001/archinte.161.1.45 · Cited by 329 · see citing works
Epidemiology and clinical characteristics of GERD in the Japanese population
Fujiwara, Y., & Arakawa, T. (2009) · Journal of Gastroenterology · doi:10.1007/s00535-009-0047-5 · Cited by 326 · see citing works
Pathogenesis of Chronic Persistent Cough Associated with Gastroesophageal Reflux
Ing, A., Ngu, M. C., & Breslin, A. B. X. (1994) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.149.1.8111576 · Cited by 319 · see citing works
Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015
Iwakiri, K., Kinoshita, Y., Habu, Y., Oshima, T., Manabe, N., Fujiwara, Y., Nagahara, A., Kawamura, O., Iwakiri, R., Ozawa, S., et al. (2016) · Journal of Gastroenterology · doi:10.1007/s00535-016-1227-8 · Cited by 284 · see citing works
Rossor, M. N. (1982) · The Lancet · doi:10.1016/s0140-6736(82)91212-0 · Cited by 283 · see citing works
The Effect of Nonvisible Sleep Fragmentation on Daytime Function
Martin, S. E., WRAITH, P. K., Deary, I. J., & Douglas, N. J. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.155.5.9154863 · Cited by 274 · see citing works
Obstructive sleep apnea and gastroesophageal reflux
Ing, A., Ngu, M., & Breslin, A. B. X. (2000) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00350-2 · Cited by 272 · see citing works
Epidemiology of Gastroesophageal Reflux Disease in Asia: A Systematic Review
Jung, H. (2011) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2011.17.1.14 · Cited by 257 · see citing works
Sleep Deprivation Is Hyperalgesic in Patients With Gastroesophageal Reflux Disease
Schey, R., Dickman, R. M., Parthasarathy, S., Quan, S. F., Wendel, C. S., Merchant, J., Powers, J., Han, B., Handel, D. V., & Fass, R. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.09.039 · Cited by 224 · see citing works
Self-citationShirai, N., Furuta, T., Moriyama, Y., et al. (2001) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2001.01108.x · Cited by 220 · see citing works
Sleep duration and all-cause mortality: a critical review of measurement and associations
Kurina, L. M., McClintock, M. K., Chen, J.-H., Waite, L. J., Thisted, R. A., & Lauderdale, D. S. (2013) · Annals of Epidemiology · doi:10.1016/j.annepidem.2013.03.015 · Cited by 218 · see citing works
Rate of Flow of Human Parotid, Sublingual, and Submaxillary Secretions During Sleep
Schneyer, L. H., Pigman, W., Hanahan, L., et al. (1956) · Journal of Dental Research · doi:10.1177/00220345560350010301 · Cited by 212 · see citing works
Johnson, D. A., Orr, W. C., Crawley, J. A., Traxler, B. M., McCullough, J. P., Brown, K. A., & Roth, T. G. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.00285.x · Cited by 209 · see citing works
Ganz, R. A., Edmundowicz, S. A., Taiganides, P. A., et al. (2015) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2015.05.028 · Cited by 200 · see citing works
Alginate therapy is effective treatment for GERD symptoms: a systematic review and meta-analysis
Leiman, D. A., Riff, B. P., Morgan, S., et al. (2017) · Diseases of the Esophagus · doi:10.1093/dote/dow020 · Cited by 183 · see citing works
Sontag, S. J., O'Connell, S. M., Khandelwal, S., Greenlee, H. B., Schnell, T. G., Nemchausky, B. A., Chejfec, G., Miller, T. Q., Seidel, J., & Sonnenberg, A. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07503.x · Cited by 182 · see citing works
Predictors of Heartburn During Sleep in a Large Prospective Cohort Study
Fass, R., Quan, S. F., O’Connor, G. T., Ervin, A., & Iber, C. (2005) · CHEST Journal · doi:10.1378/chest.127.5.1658 · Cited by 182 · see citing works
Self-citationAcid clearance during sleep in the pathogenesis of reflux esophagitis
Orr, W. C., ROBINSON, M. G., & Johnson, L. F. (1981) · Digestive Diseases and Sciences · doi:10.1007/bf01313584 · Cited by 166 · see citing works
Parasomnias: An Updated Review
Howell, M. J. (2012) · Neurotherapeutics · doi:10.1007/s13311-012-0143-8 · Cited by 165 · see citing works
Johnson, L. F., & DeMeester, T. R. (1981) · Digestive Diseases and Sciences · doi:10.1007/bf01316854 · Cited by 161 · see citing works
Bubenik, G. A. (2001) · Neurosignals · doi:10.1159/000046903 · Cited by 161 · see citing works
Dental Erosion and Acid Reflux Disease
Schroeder, P. L., Filler, S. J., Ramirez, B., et al. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-122-11-199506010-00001 · Cited by 158 · see citing works
Correlation of oesophageal acid exposure with Barrett's oesophagus length
Fass, R., Hell, R. W., Garewal, H. S., et al. (2001) · Gut · doi:10.1136/gut.48.3.310 · Cited by 150 · see citing works
Self-citationAssociation Between Dinner-to-Bed Time and Gastro-Esophageal Reflux Disease
Fujiwara, Y., Machida, A., Watanabe, Y., et al. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.00354.x · Cited by 150 · see citing works
Tack, J. F., Becher, A., Mulligan, C., et al. (2012) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2012.05086.x · Cited by 150 · see citing works
The significance of saliva during sleep and the relevance of oromotor movements
Thie, N. M. R., Kato, T., Bader, G. G., Montplaisir, J. Y., & Lavigne, G. J. (2002) · Sleep Medicine Reviews · doi:10.1053/smrv.2001.0183 · Cited by 148 · see citing works
Sleeping on a wedge diminishes exposure of the esophagus to refluxed acid
Hamilton, J., Boisen, R. J., Yamamoto, D. T., et al. (1988) · Digestive Diseases and Sciences · doi:10.1007/bf01798350 · Cited by 144 · see citing works
Khoury, R., Camacho-Lobato, L., Katz, P. O., et al. (1999) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.01279.x · Cited by 135 · see citing works
Impaired Swallowing Reflex in Patients With Obstructive Sleep Apnea Syndrome
Teramoto, S., Sudo, E., Matsuse, T., Ohga, E., Ishii, T., Ouchi, Y., & Fukuchi, Y. (1999) · CHEST Journal · doi:10.1378/chest.116.1.17 · Cited by 134 · see citing works
Sleep and chronic obstructive pulmonary disease
Weitzenblum, E., & Chaouat, A. (2004) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2004.03.006 · Cited by 131 · see citing works
Nocturnal Reflux Episodes Following the Administration of a Standardized Meal. Does Timing Matter?
Piesman, M., Hwang, I., Maydonovitch, C. L., & Wong, R. K. H. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01348.x · Cited by 129 · see citing works
Patterns of acid reflux in complicated oesophagitis.
Robertson, D. A., Aldersley, M. A., Shepherd, H. A., et al. (1987) · Gut · doi:10.1136/gut.28.11.1484 · Cited by 126 · see citing works
Arousal in patients with gastro-oesophageal reflux and sleep apnoea
Penzel, T., Becker, H. F., Brandenburg, U., Labunski, T., Pankow, W., & Peter, J. H. (1999) · European Respiratory Journal · doi:10.1183/09031936.99.14612669 · Cited by 125 · see citing works
Harvey, R. F., Hadley, N., Gill, T., et al. (1987) · The Lancet · doi:10.1016/s0140-6736(87)91332-8 · Cited by 116 · see citing works
Symptomatic Gastroesophageal Reflux in Subjects With a Breathing Sleep Disorder
Valipour, A., Makker, H. K., Hardy, R., Emegbo, S., Toma, T., & Spiro, S. G. (2002) · CHEST Journal · doi:10.1378/chest.121.6.1748 · Cited by 113 · see citing works
Dickman, R. M., Green, C., Fass, S. S., Quan, S. F., Dekel, R., Risner-Adler, S., & Fass, R. (2007) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.26915 · Cited by 113 · see citing works
Self-citationThe relationship between gastroesophageal reflux disease and obstructive sleep apnea
Demeter, P., & Pap, Á. (2004) · Journal of Gastroenterology · doi:10.1007/s00535-004-1416-8 · Cited by 112 · see citing works
Effects of Gastroesophageal Reflux Disease on Sleep and Outcomes
Mody, R., Bolge, S. C., Kannan, H., & Fass, R. (2009) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2009.04.005 · Cited by 110 · see citing works
Self-citationTawk, M. M., Goodrich, S., Kinasewitz, G. T., & Orr, W. C. (2006) · CHEST Journal · doi:10.1378/chest.130.4.1003 · Cited by 107 · see citing works
Gerson, L. B., & Fass, R. (2008) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2008.11.021 · Cited by 106 · see citing works
Self-citationEffects of Posture on Gastro-Oesophageal Reflux
Stanciu, C., & Bennett, J. R., Jr. (2009) · Digestion · doi:10.1159/000197991 · Cited by 104 · see citing works
Role of GERD in chronic resistant sinusitis: a prospective, open label, pilot trial
DiBaise, J. K. (2002) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(02)03954-0 · Cited by 101 · see citing works
Risk factors for gastroesophageal reflux disease – the role of diet
Jarosz, M. J., & Taraszewska, A. (2014) · Gastroenterology Review · doi:10.5114/pg.2014.46166 · Cited by 101 · see citing works
Jansson, C., Nordenstedt, H., Wallander, M.-A. A., et al. (2009) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2009.03.007 · Cited by 100 · see citing works
Role of GERD in chronic resistant sinusitis: a prospective, open label, pilot trial
DiBaise, J. K., Olusola, B. F., Huerter, J. V., et al. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05598.x · Cited by 100 · see citing works
Aiolfi, A., Asti, E., Bernardi, D. T., et al. (2018) · International Journal of Surgery · doi:10.1016/j.ijsu.2018.02.041 · Cited by 96 · see citing works
Long-term Results of Surgical Treatment for Gastroesophageal Reflux in Asthmatic Patients
Perrin-Fayolle, M., Gormand, F., Braillon, G. G., Lombard-Platet, R., Vignal, J., Azzar, D., Forichon, J., & Adeleine, P. (1989) · CHEST Journal · doi:10.1378/chest.96.1.40 · Cited by 95 · see citing works
Is there a relationship between obstructive sleep apnea and gastroesophageal reflux disease?
Morse, C. A., Quan, S. F., Mays, M. Z., Green, C., Stephen, G., & Fass, R. (2004) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(04)00347-7 · Cited by 95 · see citing works
Self-citationFass, R., Johnson, D. A., Orr, W. C., et al. (2011) · The American Journal of Gastroenterology · doi:10.1038/ajg.2010.458 · Cited by 95 · see citing works
Self-citationMelatonin and serotonin effects on gastrointestinal motility.
Pj, T., Królczyk, G., Gil, K., Zurowski, D., & Nowak, Ł. (2007) · PubMed · Cited by 94 · see citing works
Katz, P. O., Koch, F. K., BALLARD, E. D., et al. (2007) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.03191.x · Cited by 93 · see citing works
Fass, R., Chey, W. D., Zakko, S. F., Andhivarothai, N., Palmer, R. N., Pérez, M. C., & Atkinson, S. N. (2009) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2009.04013.x · Cited by 93 · see citing works
Self-citationWc, O., Allen, M. L., & ROBINSON, M. G. (1994) · PubMed · Cited by 93 · see citing works
Khan, B. A., Sodhi, J. S., Zargar, S. A., et al. (2011) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2011.06968.x · Cited by 92 · see citing works
Gastroesophageal Reflux and Obstructive Sleep Apnea
Senior, B. A., Khan, M. J., Schwimmer, C., Rosenthal, L. D., & Benninger, M. (2001) · The Laryngoscope · doi:10.1097/00005537-200112000-00012 · Cited by 92 · see citing works
Effect of Different Recumbent Positions on Postprandial Gastroesophageal Reflux in Normal Subjects
van Herwaarden, M., Katzka, D. A., Smout, A. J. P. M., Samsom, M., Gideon, M., & Castell, D. O. (2000) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(00)01973-0 · Cited by 90 · see citing works
Use of a positional therapy device significantly improves nocturnal gastroesophageal reflux symptoms
Allampati, S., López, R., Thota, P., et al. (2016) · Diseases of the Esophagus · doi:10.1111/dote.12495 · Cited by 89 · see citing works
Wu, Z., Yang, X., Niu, X., Xiao, X.-Y., & Chen, X. (2018) · Sleep And Breathing · doi:10.1007/s11325-018-1691-x · Cited by 89 · see citing works
Kim, J., Oh, S.-W., Myung, S.-K., Kwon, H., Lee, C., Yun, J. M., Lee, H. K., & The Korean Meta-analysis (KORMA) Study Group (2014) · Diseases of the Esophagus · doi:10.1111/dote.12099 · Cited by 88 · see citing works
McCallum, R. W., Kline, M. M., Curry, N., et al. (1975) · Gastroenterology · doi:10.1016/s0016-5085(75)80223-x · Cited by 84 · see citing works
Ellis, F. H. (1992) · The Annals of Thoracic Surgery · doi:10.1016/0003-4975(92)90112-h · Cited by 80 · see citing works
Atkinson, M., & Gelder, A. (1977) · Digestive Diseases and Sciences · doi:10.1007/bf01072195 · Cited by 78 · see citing works
Human Adult Deglutition during Sleep
Sato, K., & Nakashima, T. (2006) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348940611500503 · Cited by 78 · see citing works
Gastroesophageal reflux in patients with sleep apnea syndrome.
Ki, G., Karaus, M., Heinemann, S., Körber, S., Dorow, P., & Hampel, K. E. (1995) · PubMed · Cited by 77 · see citing works
Meta‐analysis: the efficacy of over‐the‐counter gastro‐oesophageal reflux disease therapies
Tran, T. N., LOWRY, A. M., & EL‐SERAG, H. B. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.03135.x · Cited by 75 · see citing works
The effect of acid suppression on sleep patterns and sleep‐related gastro‐oesophageal reflux
Orr, W. C., Goodrich, S., & Robert, J. J. T. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02310.x · Cited by 74 · see citing works
Mainie, I., Tutuian, R. I., & Castell, D. O. (2008) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e31814a4e5c · Cited by 72 · see citing works
Helm, J. F. (1986) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-198606001-00003 · Cited by 70 · see citing works
Castell, D. O., Bagin, R. G., Goldlust, B., Major, J., & Hepburn, B. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02513.x · Cited by 70 · see citing works
Symptomatic Effect of a Low-Dose Antacid Regimen in Reflux Oesophagitis
Weberg, R., & Berstad, A. (1989) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365528909093066 · Cited by 69 · see citing works
Sahara, S., Sugimoto, M., Uotani, T., et al. (2013) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12492 · Cited by 69 · see citing works
Prevalence and Predictors of Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy
Althuwaini, S., Bamehriz, F. Y., Aldohayan, A., Alshammari, W., Alhaidar, S., Alotaibi, M. B., Alanazi, A., Alsahabi, H., & Almadi, M. A. (2017) · Obesity Surgery · doi:10.1007/s11695-017-2971-4 · Cited by 69 · see citing works
Clinical consequences of silent gastroesophageal reflux disease
Fass, R., & Dickman, R. M. (2006) · Current Gastroenterology Reports · doi:10.1007/s11894-006-0075-8 · Cited by 68 · see citing works
Self-citationBaşoğlu, Ö. K., Vardar, R., Taşbakan, M. S., Uçar, Z. Z., Ayık, S., Köse, T., & Bor, S. (2014) · Sleep And Breathing · doi:10.1007/s11325-014-1051-4 · Cited by 66 · see citing works
A review of medical therapy for proton pump inhibitor nonresponsive gastroesophageal reflux disease
Hillman, L., Yadlapati, R. H., Thuluvath, A. J., et al. (2017) · Diseases of the Esophagus · doi:10.1093/dote/dox055 · Cited by 64 · see citing works
Effect of Zolpidem on the Sleep Arousal Response to Nocturnal Esophageal Acid Exposure
Gagliardi, G. S., Shah, A. P., Goldstein, M., et al. (2009) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2009.04.026 · Cited by 62 · see citing works
Scholten, T., Gatz, G., & Hole, U. (2003) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01745.x · Cited by 62 · see citing works
Hyun, M. K., Baek, Y., & Lee, S. (2019) · BMC Gastroenterology · doi:10.1186/s12876-019-0945-9 · Cited by 62 · see citing works
Sleep Symptoms and Gastroesophageal Reflux
Chen, C., Robert, J. J. T., & Orr, W. C. (2008) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e31802fc1bc · Cited by 61 · see citing works
Review article: sleep‐related gastro‐oesophageal reflux as a distinct clinical entity
Orr, W. C. (2009) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2009.04124.x · Cited by 61 · see citing works
Age- and gender-related differences in 24-hour esophageal pH monitoring of normal subjects
Fass, R., Sampliner, R. E., Mackel, C., McGee, D., & Rappaport, W. (1993) · Digestive Diseases and Sciences · doi:10.1007/bf01296120 · Cited by 56 · see citing works
Self-citationThe Effect of Esophageal Acid Volume on Arousals from Sleep and Acid Clearance
Orr, W. C., ROBINSON, M. G., & Johnson, L. F. (1991) · CHEST Journal · doi:10.1378/chest.99.2.351 · Cited by 56 · see citing works
Bajaj, J. S., Bajaj, S., Dua, K. S., Jaradeh, S. S., Rittmann, T., Hofmann, C. L., & Shaker, R. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.10.003 · Cited by 56 · see citing works
Risk Factors for Gastroesophageal Reflux Disease in Saudi Arabia
Alkhathami, A. M., Alzahrani, A. A., Alzhrani, M. A., et al. (2017) · Gastroenterology Research · doi:10.14740/gr906w · Cited by 56 · see citing works
Orr, W. C., Goodrich, S., Wright, S., Shepherd, K., & Mellow, M. (2012) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2012.01900.x · Cited by 55 · see citing works
Sinusitis and Gastroesophageal Reflux Disease
DiBaise, J. K., Huerter, J. V., & Quigley, E. M. M. (1998) · Annals of Internal Medicine · doi:10.7326/0003-4819-129-12-199812150-00029 · Cited by 53 · see citing works
The effect of gastro‐oesophageal reflux and omeprazole on key sleep parameters
DiMarino, A. J., Banwait, K. S., ESCHINGER, E., Greenberg, A. S., Dimarino, M., Doghramji, K., & Cohen, S. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02573.x · Cited by 49 · see citing works
Responses to Different Levels of Esophageal Acidification During Waking and Sleep
Orr, W. C., & Johnson, L. F. (1998) · Digestive Diseases and Sciences · doi:10.1023/a:1018877516130 · Cited by 48 · see citing works
Wilson, J. F. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-10-200505170-00026 · Cited by 48 · see citing works
Effect of Different Recumbent Positions on Postprandial Gastroesophageal Reflux in Normal Subjects
van Herwaarden, M. A., Katzka, D. A., Smout, A. J. P. M., et al. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.03180.x · Cited by 48 · see citing works
Dickman, R. M., Parthasarathy, S., Malagon, I. B., Jones, P., HAN, B., Powers, J., & Fass, R. (2007) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2007.03347.x · Cited by 47 · see citing works
Self-citationNighttime Reflux Is Primarily an Early Event
Hila, A., & Castell, D. O. (2005) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000170762.52072.a9 · Cited by 47 · see citing works
Patterns of diet‐related practices and prevalence of gastro‐esophageal reflux disease
Esmaillzadeh, A., Keshteli, A. H., Feizi, A., et al. (2013) · Neurogastroenterology & Motility · doi:10.1111/nmo.12192 · Cited by 47 · see citing works
Chand, N., Johnson, D. A., Tabangin, M. E., & Ware, J. C. (2004) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2004.02213.x · Cited by 47 · see citing works
Measuring Serum Melatonin in Epidemiologic Studies
Hsing, A. W., Meyer, T. E., Niwa, S., Quraishi, S. M., & Chu, L. W. (2010) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-10-0004 · Cited by 47 · see citing works
A Novel Sleep Positioning Device Reduces Gastroesophageal Reflux
Person, E., Rife, C., Freeman, J., et al. (2015) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000000359 · Cited by 46 · see citing works
Additional bedtime H2-receptor antagonist for the control of nocturnal gastric acid breakthrough
Wang, Y., Pan, T., Wang, Q., & Guo, Z. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004275.pub3 · Cited by 45 · see citing works
Modulation of upper and lower esophageal sphincter tone during sleep
Eastwood, P. R., Katagiri, S., Shepherd, K., & Hillman, D. R. (2007) · Sleep Medicine · doi:10.1016/j.sleep.2006.08.016 · Cited by 43 · see citing works
Brzozowska, I. M., Strzałka, M., Drozdowicz, D., Konturek, S. J., & Brzozowski, T. (2014) · Current Pharmaceutical Design · doi:10.2174/1381612819666131119110258 · Cited by 43 · see citing works
Lei, W., Chang, W., Wong, M., et al. (2018) · Digestion · doi:10.1159/000490941 · Cited by 41 · see citing works
Quality of life and antireflux medication use following laparoscopic Nissen fundoplication.
Bloomston, M., Zervos, E. E., Gonzalez, R., et al. (1998) · PubMed · Cited by 39 · see citing works
The relationship between gastroesophageal reflux disease and sleep
Fass, R. (2009) · Current Gastroenterology Reports · doi:10.1007/s11894-009-0032-4 · Cited by 37 · see citing works
Self-citationFujiwara, Y., Kohata, Y., Kaji, M., Nebiki, H., Yamasaki, T., Sasaki, E., Hayákawa, T., Machida, H., Tanigawa, T., Watanabe, K., et al. (2010) · Digestion · doi:10.1159/000253849 · Cited by 37 · see citing works
Self-citationPoh, C. H., Allen, L. M., Gąsiorowska, A., Navarro-Rodríguez, T., Quan, S. F., Malagon, I. B., Powers, J., Willis, M. R., Ashpole, N. E., & Fass, R. (2010) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2010.05.022 · Cited by 36 · see citing works
Self-citationJaniak, P., Thumshirn, M. B., Menne, D., et al. (2007) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2007.03469.x · Cited by 35 · see citing works
Ip, S., Tatsioni, A., Conant, A., Karagozian, R., Fu, L. Y., Chew, P. W., Raman, G., Lau, J. T. F., & Bonis, P. A. (2009) · The American Journal of Gastroenterology · doi:10.1038/ajg.2008.123 · Cited by 35 · see citing works
Zadeh, J. R., Andreoni, A. R., Treitl, D., et al. (2018) · Medical Devices Evidence and Research · doi:10.2147/mder.s113679 · Cited by 35 · see citing works
Yamasaki, T., Quan, S. F., & Fass, R. (2019) · Neurogastroenterology & Motility · doi:10.1111/nmo.13705 · Cited by 33 · see citing works
Self-citationReview article: impact of night‐time reflux on lifestyle − unrecognized issues in reflux disease
Shaker, R., Brunton, S., Elfant, A., et al. (2004) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2004.02237.x · Cited by 32 · see citing works
Pehlivanov, N., Sarosiek, I., Whitman, R. A., et al. (2002) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2002.01225.x · Cited by 32 · see citing works
Nocturnal secretion of melatonin in patients with upper digestive tract disorders.
Klupińska, G., Wiśniewska‐Jarosińska, M., Harasiuk, A., Chojnacki, C. J., Stec‐Michalska, K., Błasiak, J., Reiter, R. J., & Chojnacki, J. (2006) · PubMed · Cited by 32 · see citing works
Surgical trial investigating nocturnal gastroesophageal reflux and sleep (STINGERS)
Cohen, J. A., Arain, A. M., Harris, P. A., et al. (2002) · Surgical Endoscopy · doi:10.1007/s00464-002-8912-9 · Cited by 31 · see citing works
Occurrence of Nighttime Gastroesophageal Reflux in Disturbed and Normal Sleepers
Orr, W. C., Goodrich, S., Fernström, P., et al. (2008) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2008.06.016 · Cited by 31 · see citing works
Disruption of Normal Gastric Myoelectric Functioning by Sleep
Elsenbruch, S., Orr, W. C., HARNISH, M., et al. (1999) · SLEEP · doi:10.1093/sleep/22.4.453 · Cited by 31 · see citing works
Majka, J., Wierdak, M., Brzozowska, I., Magierowski, M., Szlachcic, A., Wojcik, D., Kwiecien, S., Magierowska, K., Zagajewski, J., & Brzozowski, T. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19072033 · Cited by 31 · see citing works
Dickman, R. M., Shapiro, M. J., Malagon, I. B., et al. (2007) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2007.00929.x · Cited by 30 · see citing works
Kim, Y., Lee, Y. J., Park, J. S., Cho, Y.-J., Yoon, H. I., Lee, J. H., Lee, C.-T., & Kim, S. J. (2018) · Sleep and Breathing · doi:10.1007/s11325-017-1533-2 · Cited by 30 · see citing works
Haase, A., Fallet, S., Otto, M., et al. (2015) · Clinical and Experimental Gastroenterology · doi:10.2147/ceg.s91964 · Cited by 29 · see citing works
Caparroz, F. A., Campanholo, M. D. A. T., Regina, C. G., Park, S. W., Haddad, L., Gregório, L. C., & Haddad, F. L. M. (2019) · Brazilian Journal of Otorhinolaryngology · doi:10.1016/j.bjorl.2018.03.007 · Cited by 27 · see citing works
Goh, K., Choi, M., Hsu, W. P. I., et al. (2014) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.12655 · Cited by 26 · see citing works
Recurrence of gastroesophageal reflux disease correlated with a short dinner‐to‐bedtime interval
Yang, J. H., Kang, H. S., Lee, S., et al. (2013) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.12455 · Cited by 26 · see citing works
Naps Are Associated More Commonly With Gastroesophageal Reflux, Compared With Nocturnal Sleep
Nasrollah, L., Maradey–Romero, C., Jha, L. K., Gadam, R., Quan, S. F., & Fass, R. (2014) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2014.05.017 · Cited by 26 · see citing works
Self-citationDhiman, R. K., Saraswat, V. A., Mishra, A., et al. (1996) · Digestive Diseases and Sciences · doi:10.1007/bf02213133 · Cited by 26 · see citing works
Jha, L. K., Fass, R., Gadam, R., et al. (2015) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000000322 · Cited by 25 · see citing works
Self-citationAllen, L. M., Poh, C. H., Gąsiorowska, A., et al. (2010) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04403.x · Cited by 25 · see citing works
Sleep disorders and gastrointestinal symptoms: chicken, egg or vicious cycle?
Maneerattanaporn, M., & Chey, W. D. (2009) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01254.x · Cited by 22 · see citing works
Lang, G. D., & Dougall, A. (1989) · PubMed · Cited by 21 · see citing works
Nocturnal Gastroesophageal Reflux Revisited by Impedance-pH Monitoring
Fornari, F., Blondeau, K., Mertens, V., et al. (2011) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2011.17.2.148 · Cited by 21 · see citing works
Predicting Obstructive Sleep Apnea Status With the Reflux Symptom Index in a Sleep Study Population
Teklu, M., Gouveia, C. J., Yalamanchili, A., Ghadersohi, S., Price, C. P. E., Bove, M. J., Attarian, H. P., & Tan, B. K. (2020) · The Laryngoscope · doi:10.1002/lary.28592 · Cited by 21 · see citing works
Nocturnal Gastroesophageal Reflux
Teramoto, S., Kume, H., & Ouchi, Y. (2002) · CHEST Journal · doi:10.1378/chest.122.6.2266 · Cited by 20 · see citing works
Riser’s reflux - an eye-opening experience
Poh, C. H., Allen, L. M., Malagon, I. B., et al. (2010) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2009.01446.x · Cited by 20 · see citing works
Malfertheiner, S. F., Seelbach-Göbel, B., Costa, S., Ernst, W., Reuschel, E., Zeman, F., Malfertheiner, P., & Malfertheiner, M. V. (2017) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000000905 · Cited by 20 · see citing works
Konturek, P. C., Brzozowska, I. M., Targosz, A., Pawlik, M., Kania, J., Hess, T., Kwiecień, S., Konturek, S. J., Reiter, R. J., & Brzozowski, T. (2013) · Journal of Pineal Research · doi:10.1111/jpi.12048 · Cited by 19 · see citing works
Deglutition and respiratory patterns during sleep in the aged
Sato, K., Sato, K., Chitose, S., et al. (2016) · Acta Oto-Laryngologica · doi:10.1080/00016489.2016.1203991 · Cited by 19 · see citing works
Ahmed, R., Mahavadi, S., Al-Shboul, O. A., et al. (2013) · Regulatory Peptides · doi:10.1016/j.regpep.2013.03.028 · Cited by 18 · see citing works
Dean, B. B., Aguilar, D., Johnson, L. F., et al. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-009-0885-2 · Cited by 18 · see citing works
Independent association of obstructive sleep apnea with Barrett's esophagus
Hadi, Y. B., Khan, A. A., Naqvi, S. F., et al. (2019) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14779 · Cited by 18 · see citing works
Fujiwara, Y., Habu, Y., Ashida, K., et al. (2013) · Digestion · doi:10.1159/000354071 · Cited by 15 · see citing works
Budhiraja, R., Quan, S. F., Punjabi, N. M., et al. (2010) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e3181a92a57 · Cited by 14 · see citing works
Aimi, M., Komazawa, Y., Hamamoto, N., Yamane, Y., Furuta, K., Uchida, Y., Yano, S., Morita, M., Oguro, H., Miyake, T., et al. (2014) · Clinical and Translational Gastroenterology · doi:10.1038/ctg.2014.8 · Cited by 14 · see citing works
Risk Factors for Nocturnal Reflux in a Large GERD Cohort
Gaddam, S., Maddur, H., Wani, S. B., et al. (2011) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e318205e164 · Cited by 14 · see citing works
Nocturnal gastroesophageal reflux increases the risk of daytime sleepiness in women
Hägg, S. A., Emilsson, Ö. I., Franklin, K. A., et al. (2018) · Sleep Medicine · doi:10.1016/j.sleep.2018.08.036 · Cited by 14 · see citing works
Johnson, D. A., Moigne, A. L., Hugo, V., et al. (2014) · Current Medical Research and Opinion · doi:10.1185/03007995.2014.991818 · Cited by 13 · see citing works
How can we deal with the GERD treatment gap?
Triadafilopoulos, G., & Azagury, D. E. (2016) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13104 · Cited by 12 · see citing works
Cisapride and metoclopramide in the treatment of gastroesophageal reflux disease.
Jt, A., Leitão, O. R., Fassler, S., et al. (1988) · PubMed · Cited by 11 · see citing works
Kawai, T., Hirayama, Y., Oguchi, A., et al. (2017) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.16-77 · Cited by 11 · see citing works
Fornari, F., Madalosso, C. A. S., Callegari-Jacques, S. M., et al. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01170.x · Cited by 10 · see citing works
Sleep Apnea and Gastroesophageal Reflux Disease
Wolf, S. M., & Furman, Y. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-136-6-200203190-00020 · Cited by 10 · see citing works
Yi, C., Lei, W., Hung, J., et al. (2016) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.13428 · Cited by 10 · see citing works
Johnson, D. A., Moigne, A. L., Li, J., et al. (2016) · Clinical Drug Investigation · doi:10.1007/s40261-016-0398-7 · Cited by 7 · see citing works
Medical management of esophageal reflux.
Hirschowitz, B. I. (1996) · PubMed · Cited by 6 · see citing works
Chen, J., Wen, S., Hsu, C., et al. (2016) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2016.01.016 · Cited by 5 · see citing works
Seo, S. I., Bang, C. S., Kang, H. S., et al. (2017) · Diseases of the Esophagus · doi:10.1093/dote/dox034 · Cited by 4 · see citing works
Zhang, C.-C., Wang, Z., Wu, J.-M., Ji, F., Gao, X., & Hu, Z. (2012) · Indian Journal of Surgery · doi:10.1007/s12262-012-0660-z · Cited by 3 · see citing works
[Nocturnal gastroesophageal reflux. About a pH metric series].
Elleuch, N., Hefaiedh, R., Karoui, S., et al. (2015) · PubMed · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
International society of sports nutrition position stand: nutritional concerns of the female athlete
Sims, S. T., Kerksick, C. M., Smith-Ryan, A. E., Janse de Jonge, X. A. K., Hirsch, K. R., Arent, S. M., Hewlings, S. J., Kleiner, S. M., Bustillo, E., Tartar, J. L., et al. (2023) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2023.2204066 · Cited by 91 · see citing works
“higher in fat, however, may also induce heart burn [264] which may be detrimental to”
Background
- Authors
- Shibli, F., Skeans, J., Yamasaki, T., & Fass, R.
- Affiliations
- MetroHealth (US)
- Corresponding author
- Fass, Ronnie
- Venue
- Journal of Clinical Gastroenterology
- Published
- 2020-07-10
- Volume
- 54
- Issue
- 8
- Pages
- 663-674
- ISSN
- 0192-0790 (ISSN-L)
- OpenAlex
- W3042339346
- Cited by
- 43
- References
- 175
- Citations by year
- 2026: 10 · 2025: 6 · 2024: 2 · 2023: 12 · 2022: 8 · 2021: 5
- FWCI
- 5.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Surgery › Helicobacter pylori-related gastroenterology studies
- Keywords
- gastroesophageal reflux disease, nocturnal reflux, sleep disorders, obstructive sleep apnea, proton pump inhibitors, antireflux surgery, lifestyle modification
- MeSH terms
- Adult, Gastroesophageal Reflux, Humans, Sleep, Sleep Wake Disorders, Polysomnography, Sleep Apnea, Obstructive
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
