Sleep duration and all-cause mortality: a critical review of measurement and associations
Open accessAbstract
Purpose Variation in sleep duration has been linked with mortality risk. The purpose of this review is to provide an updated evaluation of the literature on sleep duration and mortality, including a critical examination of sleep duration measurement and an examination of correlates of self-reported sleep duration.Methods We conducted a systematic search of studies reporting associations between sleep duration and all-cause mortality and extracted the sleep duration measure and the measure(s) of association.Results We identified 42 prospective studies of sleep duration and mortality drawing on 35 distinct study populations worldwide. Unlike previous reviews, we find that the published literature does not support a consistent finding of an association between self-reported sleep duration and mortality. Most studies have employed survey measures of sleep duration, which are not highly correlated with estimates based on physiologic measures.Conclusions Despite a large body of literature, it is premature to conclude, as previous reviews have, that a robust, U-shaped association between sleep duration and mortality risk exists across populations. Careful attention must be paid to measurement, response bias, confounding, and reverse causation in the interpretation of associations between sleep duration and mortality.
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The precision of measurement of sleep in mortality studies is often poor.
“For example, the precision of measurement of sleep in these studies is often poor.17,27,35”
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Physiologic sleep is likely substantially less than self-reported sleep.
“It is likely that physiologic sleep is substantially less than that which is self-reported.27”
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- Authors
- Kurina, L. M., McClintock, M. K., Chen, J.-H., Waite, L. J., Thisted, R. A., & Lauderdale, D. S.
- Affiliations
- University of Chicago (US)
- Corresponding author
- Kurina, Lianne M.
- Venue
- Annals of Epidemiology
- Publisher
- Elsevier BV
- Published
- 2013-06
- Volume
- 23
- Issue
- 6
- Pages
- 361-370
- ISSN
- 1047-2797 (ISSN-L)
- PMC
- PMC3660511
- OpenAlex
- W1972070448
- Cited by
- 218
- References
- 121
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 7 · 2023: 13 · 2022: 13 · 2021: 21 · 2020: 18 · 2019: 20 · 2018: 13 · 2017: 29 · 2016: 14 · 2015: 21 · 2014: 28 · 2013: 5
- FWCI
- 3.75
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Annals of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute on Aging (R01AG042164, R01AG033903, R37AG030481)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Keywords
- sleep duration, all-cause mortality, self-reported sleep duration, U-shaped relationship, response bias, reverse causality, confounding
- MeSH terms
- Adult, Aged, Aged, 80 and over, Cause of Death, Female, Humans, Male, Middle Aged, Sleep, Time Factors, Risk Assessment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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