Environmental exposure to metals, neurodevelopment, and psychosis

Metals, Toxicity and Oxidative Stress

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Implications of Normal Brain Development for the Pathogenesis of Schizophrenia

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Glutamate Receptor Ion Channels: Structure, Regulation, and Function

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Advances in metal-induced oxidative stress and human disease

Jomová, K., & Valko, M. (2011) · Toxicology · doi:10.1016/j.tox.2011.03.001 · Cited by 3,226 · see citing works

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

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Developmental neurotoxicity of industrial chemicals

Grandjean, P., & Landrigan, P. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69665-7 · Cited by 1,984 · see citing works

Neurobehavioural effects of developmental toxicity

Grandjean, P., & Landrigan, P. J. (2014) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70278-3 · Cited by 1,886 · see citing works

Deficits in Psychologic and Classroom Performance of Children with Elevated Dentine Lead Levels

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Serologic Evidence of Prenatal Influenza in the Etiology of Schizophrenia

Brown, A. S., Begg, M. D., Gravenstein, S., Schaefer, C. A., Wyatt, R. J., Bresnahan, M. A., Babulas, V. P., & Susser, E. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.8.774 · Cited by 1,048 · see citing works

Trace elements in human physiology and pathology. Copper

Tapiero, H., Townsend, D. M., & Tew, K. D. (2003) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(03)00012-x · Cited by 1,030 · see citing works

The Role of Inflammation and Infection in Preterm Birth

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Association of Serum Interleukin 6 and C-Reactive Protein in Childhood With Depression and Psychosis in Young Adult Life: A Population-Based Longitudinal Study

Khandaker, G. M., Pearson, R. M., Zammit, S., Lewis, G., & Jones, P. B. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.1332 · Cited by 846 · see citing works

Zinc in the physiology and pathology of the CNS

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The environment and susceptibility to schizophrenia

Brown, A. S. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.09.003 · Cited by 664 · see citing works

Zinc potentiates agonist-lnduced currents at certain splice variants of the NMDA receptor

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Water Arsenic Exposure and Children’s Intellectual Function in Araihazar, Bangladesh

Wasserman, G. A., Liu, X., Parvez, F., Ahsan, H., Factor-Litvak, P. R., van Geen, A., Slavkovich, V. N., Lolacono, N. J., Cheng, Z., Hussain, I., et al. (2004) · Environmental Health Perspectives · doi:10.1289/ehp.6964 · Cited by 611 · see citing works

Schizophrenia: Diverse Approaches to a Complex Disease

Sawa, A., & Snyder, S. H. (2002) · Science · doi:10.1126/science.1070532 · Cited by 599 · see citing works

Neuropsychological impairments in schizophrenia: Integration of performance-based and brain imaging findings.

Reichenberg, A., & Harvey, P. D. (2007) · Psychological Bulletin · doi:10.1037/0033-2909.133.5.833 · Cited by 536 · see citing works

Maternal Infections and Subsequent Psychosis Among Offspring

Buka, S. L. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.11.1032 · Cited by 512 · see citing works

Maternal Exposure to Toxoplasmosis and Risk of Schizophrenia in Adult Offspring

Brown, A. S., Schaefer, C. A., Quesenberry, C. P., Liu, L., Babulas, V. P., & Susser, E. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.4.767 · Cited by 490 · see citing works

Decreased Brain Volume in Adults with Childhood Lead Exposure

Cecil, K. M., Brubaker, C. J., Adler, C. M., Dietrich, K. N., Altaye, M., Egelhoff, J. C., Wessel, S., Elangovan, I., Hornung, R., Jarvis, K., et al. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050112 · Cited by 458 · see citing works

Glutamate in Schizophrenia: A Focused Review and Meta-Analysis of 1H-MRS Studies

Marsman, A., van den Heuvel, M. P., Klomp, D. W. J., Kahn, R. S., Luijten, P. R., & Hulshoff Pol, H. E. (2013) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr069 · Cited by 457 · see citing works

Water Arsenic Exposure and Intellectual Function in 6-Year-Old Children in Araihazar, Bangladesh

Wasserman, G. A., Liu, X., Parvez, F., Ahsan, H., Factor-Litvak, P. R., Kline, J. K., van Geen, A., Slavkovich, V. N., LoIacono, N. J., Levy, D., et al. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.9501 · Cited by 407 · see citing works

Gestational Diabetes Induces Placental Genes for Chronic Stress and Inflammatory Pathways

Radaelli, T., Varastehpour, A., Catalano, P., & Hauguel-de Mouzon, S. (2003) · Diabetes · doi:10.2337/diabetes.52.12.2951 · Cited by 390 · see citing works

Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site

Wright, R. O., Amarasiriwardena, C. J., Woolf, A. D., Jim, R., & Bellinger, D. C. (2005) · NeuroToxicology · doi:10.1016/j.neuro.2005.10.001 · Cited by 387 · see citing works

Arsenic neurotoxicity — A review

Vahidnia, A., van der Voet, G. B., & de Wolff, F. A. (2007) · Human & Experimental Toxicology · doi:10.1177/0960327107084539 · Cited by 385 · see citing works

Association of arsenic, cadmium and manganese exposure with neurodevelopment and behavioural disorders in children: A systematic review and meta-analysis

Rodríguez‐Barranco, M., Lacasaña, M., Aguilar-Garduño, C., Alguacil, J., Gil, F., González-Alzaga, B., & Rojas‐García, A. (2013) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2013.03.047 · Cited by 369 · see citing works

バングラデッシュ国,アライハザールにおける,飲料水ヒ素曝露と児童知的機能

Wasserman, G. A., Liu, X., Parvez, F., Ahsan, H., Factor-Litvak, P., van Geen, A., Slavkovich, Lolacono, N. J., & Hussain, I. (2004) · Environmental Health Perspectives · Cited by 337 · see citing works

Cadmium neurotoxicity

Méndez‐Armenta, M., & Rı́os, C. (2006) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2006.11.009 · Cited by 313 · see citing works

Maternal Exposure to Respiratory Infections and Adult Schizophrenia Spectrum Disorders: A Prospective Birth Cohort Study

Brown, A. S., Schaefer, C. A., Wyatt, R. J., Goetz, R. R., Begg, M. D., Gorman, J. M., & Susser, E. (2000) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a033453 · Cited by 273 · see citing works

Arsenic and manganese exposure and children's intellectual function

Wasserman, G. A., Liu, X., Parvez, F., Factor-Litvak, P. R., Ahsan, H., Levy, D., Kline, J. K., van Geen, A., Mey, J. L., Slavkovich, V. N., et al. (2011) · NeuroToxicology · doi:10.1016/j.neuro.2011.03.009 · Cited by 261 · see citing works

Zinc takes the center stage: its paradoxical role in Alzheimer’s disease

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Maternal smoking in pregnancy alters neonatal cytokine responses

Noakes, P. S., Holt, P. G., & Prescott, S. L. (2003) · Allergy · doi:10.1034/j.1398-9995.2003.00290.x · Cited by 228 · see citing works

Molecular Neurobiology of Lead (Pb2+): Effects on Synaptic Function

Neal, A. P., & Guilarte, T. R. (2010) · Molecular Neurobiology · doi:10.1007/s12035-010-8146-0 · Cited by 203 · see citing works

Maternal smoking is associated with impaired neonatal toll-like-receptor-mediated immune responses

Noakes, P. S., Hale, J., Thomas, R., Lane, C., Devadason, S. G., & Prescott, S. L. (2006) · European Respiratory Journal · doi:10.1183/09031936.06.00050206 · Cited by 191 · see citing works

Selective blockade of NMDA‐activated channel currents may be implicated in learning deficits caused by lead

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Manganese neurotoxicity: new perspectives from behavioral, neuroimaging, and neuropathological studies in humans and non-human primates

Guilarte, T. R. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2013.00023 · Cited by 190 · see citing works

Cadmium Neurotoxicity

Rı́os, C., & Méndez‐Armenta, M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-409548-9.11571-4 · Cited by 178 · see citing works

Attentional Correlates of Dentin and Bone Lead Levels in Adolescents

Bellinger, D. C., Hu, H., Titlebaum, L., & Needleman, H. L. (1994) · Archives of Environmental Health An International Journal · doi:10.1080/00039896.1994.9937461 · Cited by 177 · see citing works

Mitochondrial Electron Transport Chain in Heavy Metal-Induced Neurotoxicity: Effects of Cadmium, Mercury, and Copper

Belyaeva, E. A., Соколова, Т. В., Emelyanova, L. V., & Zakharova, I. O. (2012) · The Scientific World JOURNAL · doi:10.1100/2012/136063 · Cited by 173 · see citing works

Current needs for increased accuracy and precision in measurements of low levels of lead in blood

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Preweaning manganese exposure causes hyperactivity, disinhibition, and spatial learning and memory deficits associated with altered dopamine receptor and transporter levels

Kern, C. H., Stanwood, G. D., & Smith, D. R. (2009) · Synapse · doi:10.1002/syn.20736 · Cited by 134 · see citing works

Altered myelination and axonal integrity in adults with childhood lead exposure: A diffusion tensor imaging study

Brubaker, C. J., Schmithorst, V. J., Haynes, E. N., Dietrich, K. N., Egelhoff, J. C., Lindquist, D. M., Lanphear, B. P., & Cecil, K. M. (2009) · NeuroToxicology · doi:10.1016/j.neuro.2009.07.007 · Cited by 132 · see citing works

Manganese levels during pregnancy and at birth: relation to environmental factors and smoking in a Southwest Quebec population

Takser, L., Lafond, J., Bouchard, M. F., St-Amour, G., & Mergler, D. (2004) · Environmental Research · doi:10.1016/j.envres.2003.11.002 · Cited by 127 · see citing works

Cadmium exposure and neuropsychological development in school children in southwestern Spain

Rodríguez‐Barranco, M., Lacasaña, M., Gil, F., Marín, J. A. L., Alguacil, J., Rohlman, D. S., González-Alzaga, B., Molina-Villalba, I., Berjano, R. M., & Aguilar-Garduño, C. (2014) · Environmental Research · doi:10.1016/j.envres.2014.06.026 · Cited by 125 · see citing works

Low-level cadmium exposure of lactating rats causes alterations in brain serotonin levels in the offspring

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Cadmium toxicity in synaptic neurotransmission in the brain

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Effects of Lead–Arsenic Combined Exposure on Central Monoaminergic Systems

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Teeth as a biomarker of past chemical exposure

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Neonatal lines in the enamel of primary teeth—A morphological and scanning electron microscopic investigation

Sabel, N., Johansson, C., Kühnisch, J., Robertson, A., Steiniger, F., Norén, J. G., Klingberg, G., & Nietzsche, S. (2008) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2008.05.003 · Cited by 112 · see citing works

Prenatal lead exposure, delta-aminolevulinic acid, and schizophrenia.

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Prenatal Exposure to Lead, δ-Aminolevulinic Acid, and Schizophrenia: Further Evidence

Opler, M. G. A., Buka, S. L., Groeger, J. L., McKeague, I. W., Wei, C., Factor-Litvak, P. R., Bresnahan, M. A., Graziano, J. H., Goldstein, J. M., Seidman, L. J., et al. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10464 · Cited by 104 · see citing works

Spatial distribution of manganese in enamel and coronal dentine of human primary teeth

Arora, M., Hare, D. J., Austin, C. E., Smith, D. R., & Doble, P. (2011) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2010.12.018 · Cited by 101 · see citing works

Spatial distribution of lead in human primary teeth as a biomarker of pre- and neonatal lead exposure

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Determining Fetal Manganese Exposure from Mantle Dentine of Deciduous Teeth

Arora, M., Bradman, A., Austin, C., Vedar, M., Holland, N., Eskenazi, B., & Smith, D. R. (2012) · Environmental Science & Technology · doi:10.1021/es203569f · Cited by 99 · see citing works

Evaluating Placental Transfer and Tissue Concentrations of Manganese in the Pregnant Rat and Fetuses after Inhalation Exposures with a PBPK Model

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A Longitudinal Study of Chronic Lead Exposure and Physical Growth in Boston Children

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Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses

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Determining Prenatal, Early Childhood and Cumulative Long-Term Lead Exposure Using Micro-Spatial Deciduous Dentine Levels

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Zinc, Manganese, Calcium, Copper, and Cadmium Level in Scalp Hair Samples of Schizophrenic Patients

Rahman, M. A., Azad, M. A. K., Hossain, M. I., Qusar, M. S., Bari, W., Begum, F., Huq, S. M. I., & Hasnat, A. (2008) · Biological Trace Element Research · doi:10.1007/s12011-008-8230-8 · Cited by 93 · see citing works

Is cognitive function linked to serum free copper levels? A cohort study in a normal population

Salustri, C., Barbati, G., Ghidoni, R., Quintiliani, L., Ciappina, S., Binetti, G. G., & Squitti, R. (2010) · Clinical Neurophysiology · doi:10.1016/j.clinph.2009.11.090 · Cited by 90 · see citing works

History of Lead Exposure in Children Revealed from Isotopic Analyses of Teeth

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Low-Level Lead Exposure Selectively Enhances Dopamine Overflow in Nucleus Accumbens: AnIn VivoElectrochemistry Time Course Assessment

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Regional alterations in the levels of brain biogenic amines, glutamate, GABA, and GAD activity due to chronic consumption of inorganic arsenic in developing and adult rats

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Manganese inhibits NMDA receptor channel function: Implications to psychiatric and cognitive effects

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Zinc-Induced Arsenite Tolerance in Mice

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Neuropsychological Impairment in Wilson's Disease

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The dose-dependent toxicological effects and potential perturbation on the neurotransmitter secretion in brain following intranasal instillation of copper nanoparticles

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Developmental lead (Pb) exposure reduces the ability of the NMDA antagonist MK-801 to suppress long-term potentiation (LTP) in the rat dentate gyrus, in vivo

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Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia

Stansfield, K. H., Ruby, K., Soares, B. D., McGlothan, J., Liu, X., & Guilarte, T. R. (2015) · Translational Psychiatry · doi:10.1038/tp.2014.147 · Cited by 61 · see citing works

Cognitive profile in Wilson's disease: A case series of 31 patients

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Marginal Zinc Deficiency Exacerbates Bone Lead Accumulation and High Dietary Zinc Attenuates Lead Accumulation at the Expense of Bone Density in Growing Rats

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Increase of striatal dopamine release by cadmium in nursing rats and its prevention by dexamethasone-induced metallothionein

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Comparative Study on Serum Levels of 10 Trace Elements in Schizophrenia

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Performance alterations associated with occupational exposure to manganese—A meta-analysis

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Effects of combined lead and cadmium exposure: Changes in schedule-controlled responding and in dopamine, serotonin, and their metabolites.

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Effects of combined lead and cadmium exposure: Changes in schedule-controlled responding and in dopamine, serotonin, and their metabolites.

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Effect of subacute manganese feeding on serotonin metabolism in the rat

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Zinc regulates the dopamine transporter in a membrane potential and chloride dependent manner

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Essential trace metals and heavy metals in newly diagnosed schizophrenic patients and those on anti-psychotic medication.

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Psychosis in an Adolescent Patient With Wilson's Disease

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Manganese and acute paranoid psychosis: a case report

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Relationship between blood metals and inflammation in taxi drivers

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Zinc modulation of serotonin uptake in the adult rat corpus callosum

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Prenatal tobacco smoke exposure, risk of schizophrenia, and severity of positive/negative symptoms

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Effect of iron and zinc deficiency on short term memory in children

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Mismanagement of Wilson′s disease as psychotic disorder

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Effects of Marginal Zinc Deficiency on Subclinical Lead Toxicity in the Rat Neonate

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Manganese Neurotoxicity Presenting with Depression, Psychosis and Catatonia

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Dietary zinc attenuates renal lead deposition but metallothionein is not directly involved

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Psychosis following arsenic (possibly thallium) poisoning. A clinical-neuropathological report.

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