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Nutritional Therapy in Pediatric Crohn Disease: The Specific Carbohydrate Diet
Abstract
OBJECTIVES: Crohn disease is characterized by chronic intestinal inflammation in the absence of a recognized etiology. Nutritional therapy in the form of exclusive enteral nutrition (EEN) has an established role within pediatric Crohn disease. Following exclusive enteral nutrition's success, many dietary therapies focusing on the elimination of specific complex carbohydrates have been anecdotally reported to be successful. METHODS: Many of these therapies have not been evaluated scientifically; therefore, we reviewed the medical records of our patients with Crohn disease on the specific carbohydrate diet (SCD). RESULTS: Seven children with Crohn disease receiving the SCD and no immunosuppressive medications were retrospectively evaluated. Duration of the dietary therapy ranged from 5 to 30 months, with an average of 14.6±10.8 months. Although the exact time of symptom resolution could not be determined through chart review, all symptoms were notably resolved at a routine clinic visit 3 months after initiating the diet. Each patient's laboratory indices, including serum albumin, C-reactive protein, hematocrit, and stool calprotectin, either normalized or significantly, improved during follow-up clinic visits. CONCLUSIONS: This chart review suggests that the SCD and other low complex carbohydrate diets may be possible therapeutic options for pediatric Crohn disease. Further prospective studies are required to fully assess the safety and efficacy of the SCD, or any other low complex SCDs in pediatric patients with Crohn disease.
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The specific carbohydrate diet was developed in the 1930s for patients with celiac disease but is also employed to treat Crohn's disease, ulcerative colitis, diverticulitis, and chronic diarrhea.
“The SCD was developed in the 1930s as a dietary protocol intended for patients with celiac disease [111] but it is also employed to treat Crohn’s disease, ulcerative colitis, diverticulitis and chronic diarrhea [112,113,114].”
From Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions (2019) · cites this paper as [113]
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“However, further research is needed to investigate the use of the SCD with larger and more diverse samples, to assess its safety and efficacy, and to understand the mechanisms underlying its effects (Cohen et al., 2014; Obih et al., 2016; Suskind et al., 2014).”
Background
Metadata
- Authors
- Suskind, D. L., Wahbeh, G., Gregory, N., Vendettuoli, H., & Christie, D.
- Affiliations
- Seattle Children's Hospital (US)
- Corresponding author
- Suskind, David L.
- Venue
- Journal of Pediatric Gastroenterology and Nutrition
- Publisher
- Wiley
- Published
- 2014-01
- Volume
- 58
- Issue
- 1
- Pages
- 87-91
- ISSN
- 0277-2116 (ISSN-L)
- 1536-4801
- OpenAlex
- W2325030700
- Cited by
- 158
- References
- 15
- Citations by year
- 2026: 7 · 2025: 11 · 2024: 10 · 2023: 12 · 2022: 16 · 2021: 15 · 2020: 9 · 2019: 18 · 2018: 11 · 2017: 19 · 2016: 11 · 2015: 13 · 2014: 6
- FWCI
- 6.64
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Pediatric Gastroenterology and Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- pediatric Crohn's disease, nutritional therapy, exclusive enteral nutrition, specific carbohydrate diet, dietary therapy, intestinal inflammation, calprotectin, C-reactive protein, serum albumin
- MeSH terms
- Adolescent, C-Reactive Protein, Edible Grain, Child, Crohn Disease, Dietary Carbohydrates, Enteral Nutrition, Female, Hematocrit, Humans, Male, Retrospective Studies, Serum Albumin, Leukocyte L1 Antigen Complex
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