Cited by 26Reproductive tract infections researchHIV/AIDS Research and InterventionsCervical Cancer and HPV Research

The effectiveness of patient-delivered partner therapy and chlamydial and gonococcal reinfection in San Francisco.

Stephens, Sally C., Bernstein, Kyle T., Katz, Mitchell H., Philip, Susan S., Klausner, Jeffrey D.·2010·Sexually Transmitted Diseases

Abstract

BACKGROUND: Patient-delivered partner therapy (PDPT) has been evaluated in randomized trials. No analysis has examined the impact of PDPT once implemented programmatically. METHODS: We examined the association between receiving PDPT and Chlamydia trachomatis and Neisseria gonorrhoeae reinfection within 1 year in patients diagnosed at San Francisco City Clinic between October 31, 2005 and March 31, 2008. Propensity score modeling was used to control for the difference between persons who did and did not receive PDPT. RESULTS: There was no significant difference between patients who received PDPT and those that did not in the crude cumulative risk for repeat infection with C. trachomatis or N. gonorrhoeae. Using propensity score analysis, the adjusted relative risk was 0.99 (0.86-1.14) for chlamydial reinfection and 0.90 (0.72-1.11) for gonococcal reinfection. Further analysis looking at men who have sex with men, men who have sex with women, and females showed no significant reductions in relative risk of reinfection for C. trachomatis or N. gonorrhoeae in these sub populations. CONCLUSIONS: Continued evaluation of PDPT on reinfection rates in real world settings as well as cost-effectiveness analyses of PDPT are needed to assess this alternative method of partner treatment.

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Crossref · 10.1097/olq.0b013e3181d8920f

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  • Data are limited regarding use of EPT for gonococcal or chlamydial infections among MSM, compared with heterosexuals.

    “Data are limited regarding use of EPT for gonococcal or chlamydial infections among MSM, compared with heterosexuals (131,132).”

    From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [131]

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Authors
Stephens, S. C., Bernstein, K. T., Katz, M. H., Philip, S. S., & Klausner, J. D.
Affiliations
  • Council of State and Territorial Epidemiologists (US)
  • San Francisco Department of Public Health (US)
Corresponding author
  • Stephens, Sally C.
  • Bernstein, Kyle T.
  • Katz, Mitchell H.
  • Philip, Susan S.
  • Klausner, Jeffrey D.
Venue
Sexually Transmitted Diseases
Published
2010-08
Volume
37
Issue
8
Pages
525-529
ISSN
0148-5717 (ISSN-L)
OpenAlex
W2062345994
Cited by
26
References
14
Citations by year
2022: 1 · 2021: 1 · 2019: 2 · 2017: 3 · 2016: 1 · 2015: 4 · 2014: 1 · 2013: 2 · 2012: 2
FWCI
3.82
Type
journal article
Language
en
Open access
closed
Locations
  • Sexually Transmitted Diseases (publishedVersion)
  • PubMed (publishedVersion)
Funders
Centers for Disease Control and Prevention (1h25ps001354-01)
Topics
  • Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
  • Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
  • Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
Keywords
patient-delivered partner therapy, Chlamydia trachomatis, Neisseria gonorrhoeae, sexually transmitted infections, partner notification, men who have sex with men, men who have sex with women
MeSH terms
Adult, Anti-Bacterial Agents, Chlamydia, Chlamydia Infections, Chlamydia trachomatis, Female, Gonorrhea, Humans, Male, Middle Aged, Neisseria gonorrhoeae, San Francisco, Sexual Partners, Treatment Outcome, Secondary Prevention, Young Adult

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