A randomized, controlled trial of inSPOT and patient-delivered partner therapy for gonorrhea and chlamydial infection among men who have sex with men.
Abstract
BACKGROUND: The efficacy of patient-delivered partner therapy (PDPT) and inSPOT, a web-based partner notification service, in increasing partner treatment and/or notification among men who have sex with men (MSM) has not been evaluated. METHODS: We enrolled MSM with chlamydia and/or gonorrhea in a randomized, controlled trial with the following 4 arms: inSPOT, PDPT, combined inSPOT and PDPT (inSPOT/PDPT), and standard partner management. Men were offered enrollment when contacted for partner services. Participants completed baseline and follow-up interviews approximately 2 weeks apart. RESULTS: We offered enrollment to 393 eligible MSM, of whom 75 (19%) enrolled and 318 (81%) declined enrollment. The study was halted early due to low enrollment. Among the 75 enrollees, 53 (71%) completed baseline and follow-up interviews. Of these 53 men, 13, 10, 17, and 13 were assigned to the PDPT, inSPOT, inSPOT/PDPT, and standard arms, respectively; participants provided information about 186 partners. The number of partners treated per original patient was 2.33 in the PDPT arm and 1.52 in the non-PDPT arms. PDPT assignment increased the mean number of partners treated per original patient by 54% (ratio of means = 1.54, 95% confidence interval: 1.01-2.34), after adjustment for inSPOT assignment. Among 27 men assigned to inSPOT or inSPOT/PDPT, 1 (4%) used inSPOT to notify ≥ 1 partner. inSPOT did not affect partner notification, but decreased partner human immunodeficiency virus testing (ratio of means: 0.42, 95% confidence interval: 0.18-0.99). CONCLUSIONS: PDPT may increase partner treatment among MSM. Few MSM appear to be willing to use inSPOT to notify their sex partners. Traditional randomized trials of partner notification strategies may not be feasible among MSM.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Data are limited regarding use of EPT for gonococcal or chlamydial infections among MSM, compared with heterosexuals.
“Data are limited regarding use of EPT for gonococcal or chlamydial infections among MSM, compared with heterosexuals (131,132).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [132]
Cites
Golden, M. R., Whittington, W. L. H., Handsfield, H. H., Hughes, J. P., Stamm, W. E., Hogben, M., Clark, A., Malinski, C., Helmers, J. R. L., Thomas, K. K., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa041681 · Cited by 470 · see citing works
Self-citationSCHILLINGER, J. A., KISSINGER, P., CALVET, H., WHITTINGTON, W. L. H., RANSOM, R. L., STERNBERG, M. R., BERMAN, S. M., KENT, C. K., MARTIN, D. H., OH, M. K., et al. (2003) · Sexually Transmitted Diseases · doi:10.1097/00007435-200301000-00011 · Cited by 251 · see citing works
Results of a Randomized Trial of Partner Notification in Cases of HIV Infection in North Carolina
Landis, S. E., Schoenbach, V. J., Weber, D. J., Mittal, M., Krishan, B., Lewis, K., & Koch, G. G. (1992) · New England Journal of Medicine · doi:10.1056/nejm199201093260205 · Cited by 200 · see citing works
Patient-delivered partner treatment for male urethritis: a randomized, controlled trial.
Kissinger, P., Mohammed, H., Richardson-Alston, G., Leichliter, J. S., Taylor, S. N., Martin, D. H., & Farley, T. A. (2005) · Clinical Infectious Diseases · doi:10.1086/432476 · Cited by 174 · see citing works
inSPOT: The First Online STD Partner Notification System Using Electronic Postcards
Levine, D., Woodruff, A. J., Mocello, A. R., Lebrija, J., & Klausner, J. D. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050213 · Cited by 75 · see citing works
Peer referral for HIV case-finding among men who have sex with men
Golden, M. R., Gift, T. L., Brewer, D. D., Fleming, M., Hogben, M., Lawrence, J. S. S., Thiede, H., & Handsfield, H. H. (2006) · AIDS · doi:10.1097/01.aids.0000247118.74208.6a · Cited by 59 · see citing works
Self-citationPartner Management for Gonococcal and Chlamydial Infection
Golden, M. R., Whittington, W. L. H., Handsfield, H. H., Malinski, C., CLARK, A. M., Hughes, J. P., Gorbach, P. M., & Holmes, K. K. (2001) · Sexually Transmitted Diseases · doi:10.1097/00007435-200111000-00009 · Cited by 54 · see citing works
Self-citationMimiaga, M. J., Fair, A. D., Tetu, A. M., Novak, D. S., VanDerwarker, R., Bertrand, T. E., Adelson, S., & Mayer, K. H. (2007) · American Journal of Public Health · doi:10.2105/ajph.2006.098467 · Cited by 53 · see citing works
Stekler, J., Bachmann, L., Brotman, R. M., Erbelding, E. J., Lloyd, L. V., Rietmeijer, C. A., Handsfield, H. H., Holmes, K. K., & Golden, M. R. (2005) · Clinical Infectious Diseases · doi:10.1086/428043 · Cited by 51 · see citing works
HIV and STD Status Among MSM and Attitudes About Internet Partner Notification for STD Exposure
Mimiaga, M. J., Tetu, A. M., Gortmaker, S. L., Koenen, K. C., Fair, A. D., Novak, D. S., VanDerwarker, R., Bertrand, T. E., Adelson, S., & Mayer, K. H. (2008) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e3181573d84 · Cited by 47 · see citing works
Mimiaga, M. J., Reisner, S. L., Tetu, A. M., et al. (2009) · Public Health Reports · doi:10.1177/003335490912400114 · Cited by 44 · see citing works
Evaluation of an Online Partner Notification Program
RIETMEIJER, C. A. M., Westergaard, B. C., Mickiewicz, T., et al. (2011) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e31820ef796 · Cited by 44 · see citing works
Expedited Partner Therapy: A Robust Intervention
Shiely, F., Hayes, K., Thomas, K. K., Kerani, R. P., Hughes, J. P., Whittington, W. L. H., Holmes, K. K., Handsfield, H. H., Hogben, M., & Golden, M. R. (2010) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e3181e1a296 · Cited by 43 · see citing works
Self-citationDogs Are Talking: San Francisco's Social Marketing Campaign to Increase Syphilis Screening
Stephens, S. C., Bernstein, K. T., McCright, J., et al. (2010) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e3181bf5a80 · Cited by 36 · see citing works
Patient-Delivered Therapy for Chlamydia: Putting Research Into Practice
Klausner, J. D., & Chaw, J. K. (2003) · Sexually Transmitted Diseases · doi:10.1097/00007435-200306000-00007 · Cited by 33 · see citing works
Stephens, S. C., Bernstein, K. T., Katz, M. H., Philip, S. S., & Klausner, J. D. (2010) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e3181d8920f · Cited by 26 · see citing works
Patient-delivered partner medication in the UK: an unlawful but popular choice
Coyne, K. M., Cohen, C. E., Smith, N. A., Mandalia, S., & Barton, S. E. (2007) · International Journal of STD & AIDS · doi:10.1258/095646207782716956 · Cited by 17 · see citing works
Menza, T. W., Lore, J. S. D., Fleming, M., et al. (2008) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e31814fb125 · Cited by 15 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Sexually Transmitted Infections Treatment Guidelines, 2021
Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., & Bolan, G. A. (2021) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr7004a1 · Cited by 2,759 · see citing works
Althaus, C. L., Turner, K. M., Mercer, C. H., Auguste, P., Roberts, T. E., Bell, G., Herzog, S. A., Cassell, J. A., Edmunds, W. J., White, P. J., et al. (2014) · Health Technology Assessment · doi:10.3310/hta18020 · Cited by 101 · see citing works
- Authors
- Kerani, R. P., Fleming, M., DeYoung, B., & Golden, M. R.
- Affiliations
- Public Health – Seattle & King County (US)
- Corresponding author
- Kerani, Roxanne Pieper
- Fleming, Mark
- DeYoung, Bill
- Golden, Matthew Robert
- Venue
- Sexually Transmitted Diseases
- Published
- 2011-10
- Volume
- 38
- Issue
- 10
- Pages
- 941-946
- ISSN
- 0148-5717 (ISSN-L)
- OpenAlex
- W2022863747
- Cited by
- 41
- References
- 18
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 3 · 2019: 4 · 2017: 3 · 2016: 4 · 2015: 2 · 2014: 3 · 2013: 6 · 2012: 8
- FWCI
- 5.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Sexually Transmitted Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Keywords
- patient-delivered partner therapy, partner notification, gonorrhea, chlamydia, men who have sex with men, partner treatment, HIV testing, sexually transmitted infections
- MeSH terms
- Adult, Anti-Bacterial Agents, Chlamydia Infections, Follow-Up Studies, Gonorrhea, Humans, Male, Sexual Behavior, Sexual Partners, Washington, Contact Tracing, Homosexuality, Male, Internet, Young Adult, Coinfection
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review