Patient-delivered partner treatment for Trichomonas vaginalis infection: a randomized controlled trial.
Abstract
In Brief Objectives: Infections with Trichomonas vaginalis (TV) are common and recurrence rates are high. Better methods of treating partners of women with trichomoniasis are needed. Goal: To determine if patient-delivered partner treatment (PDPT) is better and more cost-effective than partner referral. Study Design: Women attending a family planning clinic who were culture-positive and treated for TV (N = 463) were randomized to either standard partner referral (PR), booklet-enhanced partner referral (BEPR), or PDPT. At baseline and 1 month, women were interviewed and cultured for TV. Detailed cost information was also collected. Results: Most women had 1 partner, were less than 24 years old, and were black. The percentage of women reporting that their partners were treated was similar for PDPT but significantly lower for BEPR compared to PR. TV follow-up rates were similar. PDPT cost less and was cost saving compared to PR and BEPR. Conclusion: Among women with TV, PDPT did not result in more partners taking the medicine or lower follow-up rates than PR but was less costly. An RCT of partner treatment for women with Trichomonas vaginalis showed that patient-delivered partner treatment was similar to partner referral for partners treated and recurrence rates but was more cost-effective.
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Existing data indicate that EPT might have a role in partner management for trichomoniasis; however, no partner management intervention has been reported to be more effective than any other in reducing trichomoniasis reinfection rates.
“Existing data indicate that EPT also might have a role in partner management for trichomoniasis; however, no partner management intervention has been reported to be more effective than any other in reducing trichomoniasis reinfection rates (129,130).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [129]
Eleven studies compared expedited partner therapy versus simple patient referral among patients with chlamydial infection, trichomoniasis, gonorrhoea or chlamydia, HIV, herpes simplex virus-2, syphilis, or any STI syndrome.
“Eleven studies compared EPT versus simple patient referral among patients with chlamydial infection (99, 113), trichomoniasis (89, 90), gonorrhoea or chlamydia (94, 95, 114-116), HIV, herpes simplex virus-2, syphilis, chlamydial infection, gonorrhoea (pharyngeal and anal) (117), or any STI syndrome (108).”
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- Authors
- Kissinger, P., Schmidt, N., Mohammed, H., Leichliter, J. S., Gift, T. L., Meadors, B., Sanders, C., & Farley, T. A.
- Affiliations
- Tulane University (US)
- Centers for Disease Control and Prevention (US)
- Louisiana State University (US)
- Corresponding author
- Kissinger, Patricia
- Schmidt, Norine
- Mohammed, Hamish
- Sanders, Cheryl
- Farley, Thomas A.
- Venue
- Sexually Transmitted Diseases
- Published
- 2006-07
- Volume
- 33
- Issue
- 7
- Pages
- 445-450
- ISSN
- 0148-5717 (ISSN-L)
- OpenAlex
- W1999105470
- Cited by
- 89
- References
- 31
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 2 · 2021: 5 · 2020: 2 · 2019: 5 · 2018: 4 · 2017: 5 · 2016: 3 · 2015: 8 · 2014: 2 · 2013: 6 · 2012: 2
- FWCI
- 4.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Sexually Transmitted Diseases (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (R30/CCR619146)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Epidemiology › Urinary Tract Infections Management
- Keywords
- Trichomonas vaginalis, trichomoniasis, cost-effectiveness, recurrence, sexually transmitted infections, women's health
- MeSH terms
- Adult, Animals, Antiprotozoal Agents, Cost-Benefit Analysis, Female, Humans, Louisiana, Male, Metronidazole, Preventive Health Services, Referral and Consultation, Sexual Partners, Trichomonas vaginalis, Trichomonas Vaginitis, Treatment Outcome
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