The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Hyperbaric Oxygen: Its Mechanisms and Efficacy
Open accessAbstract
BACKGROUND: This article outlines therapeutic mechanisms of hyperbaric oxygen therapy and reviews data on its efficacy for clinical problems seen by plastic and reconstructive surgeons. METHODS: The information in this review was obtained from the peer-reviewed medical literature. RESULTS: Principal mechanisms of hyperbaric oxygen are based on intracellular generation of reactive species of oxygen and nitrogen. Reactive species are recognized to play a central role in cell signal transduction cascades, and the discussion will focus on these pathways. Systematic reviews and randomized clinical trials support clinical use of hyperbaric oxygen for refractory diabetic wound-healing and radiation injuries; treatment of compromised flaps and grafts and ischemia-reperfusion disorders is supported by animal studies and a small number of clinical trials, but further studies are warranted. CONCLUSIONS: Clinical and mechanistic data support use of hyperbaric oxygen for a variety of disorders. Further work is needed to clarify clinical utility for some disorders and to hone patient selection criteria to improve cost efficacy.
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Du, X. L., Edelstein, D., Dimmeler, S., Ju, Q., Sui, C., & Brownlee, M. (2001) · Journal of Clinical Investigation · doi:10.1172/jci11235 · Cited by 907
Brennan, M.-L., Wu, W., Fu, X., Shen, Z., Song, W., Frost, H., Vadseth, C., Narine, L., Lenkiewicz, E., Borchers, M. T., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m112400200 · Cited by 486
Hyperbaric oxygen therapy facilitates healing of chronic foot ulcers in patients with diabetes.
Löndahl, M., Katzman, P., Nilsson, A., & Hammarlund, C. (2010) · Diabetes Care · doi:10.2337/dc09-1754 · Cited by 441 · cited 1×
“(42,43) The results continue to demonstrate that HBO2 improves outcome.”
Molecular Pathogenesis of Chronic Wounds
Stojadinovic, O., Brem, H., Vouthounis, C., Lee, B., Fallon, J., Stallcup, M., Merchant, A., Galiano, R. D., & Tomic-Canic, M. (2005) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)62953-7 · Cited by 365
Annane, D., Depondt, J., Aubert, P., Villart, M., Géhanno, P., Gajdos, P., & Chevret, S. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.09.006 · Cited by 357
Hypoxic but not anoxic stabilization of HIF-1α requires mitochondrial reactive oxygen species
Schroedl, C., McClintock, D. S., Budinger, G. R. S., & Chandel, N. S. (2002) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00014.2002 · Cited by 266
Cited by
Cheng, Y., Cheng, H., Jiang, C., Qiu, X., Wang, K., Huan, W., Yuan, A., Wu, J., & Hu, Y. (2015) · Nature Communications · doi:10.1038/ncomms9785 · Cited by 941
Correlation between intraluminal oxygen gradient and radial partitioning of intestinal microbiota
Albenberg, L., Esipova, T. V., Judge, C. P., Bittinger, K., Chen, J., Laughlin, A., Grunberg, S., Baldassano, R. N., Lewis, J. D., Li, H., et al. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.07.020 · Cited by 886
Self-citationNasole, E., Nicoletti, C., Yang, Z.-J., Girelli, A., Rubini, A., Giuffreda, F., Di Tano, A., Camporesi, E., & Bosco, G. (2014) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.3109/14756366.2012.759951 · Cited by 39
Metadata
- Authors
- Thom, S. R.
- Venue
- Plastic and Reconstructive Surgery
- Published
- 2011-01
- Volume
- 127
- Pages
- 131S-141S
- ISSN
- 0032-1052 (ISSN-L)
- OpenAlex
- W2160571310
- Cited by
- 588
- References
- 6
- FWCI
- 18.12
- Type
- journal article
- Language
- en
- Open access
- green
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