Cited by 572Musculoskeletal pain and rehabilitationFibromyalgia and Chronic Fatigue Syndrome ResearchPsychosomatic Disorders and Their Treatments

The DOI matches its Crossref record; 74 of the 75 references it cites were found in a registry or an index.

Association of Depression and Anxiety Alone and in Combination With Chronic Musculoskeletal Pain in Primary Care Patients

Open access

Bair, Matthew J., Wu, Jingwei, Damush, Teresa M., Sutherland, Jason M., Kroenke, Kurt·2008·Psychosomatic Medicine

DOI 10.1097/psy.0b013e318185c510PMC PMC2902727

Open this paper in CoChat — free account

Abstract

Objective: To assess the relationship between depression and anxiety comorbidity on pain intensity, pain-related disability, and health-related quality of life (HRQL). Methods: Analysis of baseline data from the Stepped Care for Affective Disorders and Musculoskeletal Pain (SCAMP) study. All patients (n = 500) had chronic pain (≥3-month duration) of the low back, hip, or knee. Patients with depression were oversampled for the clinical trial component of SCAMP and thus represented 50% of the study population. Patients were categorized according to pain comorbid with depression, anxiety, or both. We used analysis of variance and multivariate analysis of variance models to assess the relationships between independent and dependent variables. Results: Participants had a mean age of 59 years; they were 55% women, 56% White, and 40% Black. Fifty-four percent (n = 271) reported pain only, 20% (n = 98) had pain and depression, 3% (n = 15) had pain and anxiety, and 23% (n = 116) had pain, depression, and anxiety. Patients with pain and both depression and anxiety experienced the greatest pain severity (p < .0001) and pain-related disability (p < .0001). Psychiatric comorbidity was strongly associated with disability days in the past 3 months (p < .0001), with 18.1 days reported by patients with pain only, 32.2 days by those with pain and anxiety, 38.0 days by those with pain and depression, and 42.6 days in those with all three conditions. We found a similar pattern of poorer HRQL (p < .0001) in those with pain, depression, and anxiety. Conclusions: The added morbidity of depression and anxiety with chronic pain is strongly associated with more severe pain, greater disability, and poorer HRQL. ANOVA = analysis of variance; BPI = Brief Pain Inventory; GAD-7 = Generalized Anxiety Disorder 7-item scale; HRQL = health-related quality of life; ICD-9 = International Statistical Classification of Diseases and Related Health Problems, 9th Edition; IU = Indiana University; MANOVA = multivariate analysis of variance; MRI = magnetic resonance imaging; PA = pain and anxiety; PD = pain and depression; PDA = pain, depression, and anxiety; PHQ-9 = Patient Health Questionnaire-9; PO = pain only; SCAMP = stepped care for affective disorders and musculoskeletal pain; SCL-20 = Hopkins Symptom Checklist-20; SF-36 = Medical Outcomes Study Short Form-36; VA = Veterans Affairs.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1097/psy.0b013e318185c510

Cites

74 of 74 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910
Self-citation
A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7
Spitzer, R. L., Kroenke, K., Williams, J. B. W., & Löwe, B. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.10.1092 · Cited by 31,765
Self-citation
The structure of negative emotional states: comparison of the depression anxiety stress scales (DASS) with the beck depression and anxiety inventories.
Lovibond, P. F., & Lovibond, S. H. (1995) · Behaviour Research and Therapy · doi:10.1016/0005-7967(94)00075-u · Cited by 14,523
Validation and Utility of a Self-report Version of PRIME-MD<SUBTITLE>The PHQ Primary Care Study</SUBTITLE>
Spitzer, R. L. (1999) · JAMA · doi:10.1001/jama.282.18.1737 · Cited by 9,802
The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and Clinical Tests of Validity in Measuring Physical and Mental Health Constructs
MCHORNEY, C. A., JOHNE, W., & ANASTASIAE, R. (1993) · Medical Care · doi:10.1097/00005650-199303000-00006 · Cited by 6,681
Pain assessment: global use of the Brief Pain Inventory.
Cs, C., & Km, R. (1994) · PubMed · Cited by 5,178
Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection
Kroenke, K., Spitzer, R. L., Williams, J. B. W., Monahan, P. O., & Löwe, B. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-146-5-200703060-00004 · Cited by 4,741
Self-citation
Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
Murray, C. J., & Lopez, A. D. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07495-8 · Cited by 4,492 · cited 1×
“Major depression is the fourth leading cause of disease burden worldwide and projected to move into second place by 2020 (13).”
Background
An Ultra-Brief Screening Scale for Anxiety and Depression: The PHQ–4
Kroenke, K., Spitzer, R. L., Williams, J. B. W., & Löwe, B. (2009) · Psychosomatics · doi:10.1016/s0033-3182(09)70864-3 · Cited by 4,261
Self-citation
Untitled work
(1994) · Medical Entomology and Zoology · Cited by 4,156

Show all 75 references

Sorted by citations

The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review
Kroenke, K., Spitzer, R. L., Williams, J. B. W., & Löwe, B. (2010) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2010.03.006 · Cited by 4,057
Self-citation
RELIEVING PAIN IN AMERICA: A BLUEPRINT FOR TRANSFORMING PREVENTION, CARE, EDUCATION, AND RESEARCH
Simon, L. S. (2012) · Journal of Pain & Palliative Care Pharmacotherapy · doi:10.3109/15360288.2012.678473 · Cited by 2,200
Descending pain modulation and chronification of pain
Ossipov, M. H., Morimura, K., & Porreca, F. (2014) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0000000000000055 · Cited by 875
Neuroinflammation and comorbidity of pain and depression
Walker, A. K., Kavelaars, A., Heijnen, C. J., & Dantzer, R. (2014) · Pharmacological Reviews · doi:10.1124/pr.113.008144 · Cited by 460
Longitudinal associations between depression, anxiety, pain, and pain-related disability in chronic pain patients
Lerman, S. F., Rudich, Z., Brill, S., Shalev, H., & Shahar, G. (2015) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000158 · Cited by 408
Epigenetic mechanisms of chronic pain
Descalzi, G., Ikegami, D., Ushijima, T., Nestler, E. J., Zachariou, V., & Narita, M. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2015.02.001 · Cited by 402
Neurobiology of depression, fibromyalgia and neuropathic pain
Maletic, V. (2009) · Frontiers in bioscience · doi:10.2741/3598 · Cited by 384
Coexistence of Two Forms of LTP in ACC Provides a Synaptic Mechanism for the Interactions between Anxiety and Chronic Pain
Koga, K., Descalzi, G., Chen, T., Ko, H., Lu, J., Li, S., Son, J., Kim, T., Kwak, C., Huganir, R. L., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.12.021 · Cited by 363
Unpacking the burden: Understanding the relationships between chronic pain and comorbidity in the general population
Dominick, C. H., Blyth, F., & Nicholas, M. K. (2011) · Pain · doi:10.1016/j.pain.2011.09.018 · Cited by 262
Performance-related musculoskeletal pain, depression and music performance anxiety in professional orchestral musicians: A population study
Kenny, D. T., & Ackermann, B. J. (2013) · Psychology of Music · doi:10.1177/0305735613493953 · Cited by 237
The Mesolimbic Dopamine System in Chronic Pain and Associated Affective Comorbidities
Serafini, R. A., Pryce, K. D., & Zachariou, V. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.10.018 · Cited by 252
Association between anxiety, health-related quality of life and functional impairment in primary care patients with chronic pain
Kroenke, K., Outcalt, S., Krebs, E., Bair, M. J., Wu, J., Chumbler, N., & Yu, Z. (2013) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2013.03.020 · Cited by 212
Self-citation
Individual Expectation: An Overlooked, but Pertinent, Factor in the Treatment of Individuals Experiencing Musculoskeletal Pain
Bialosky, J. E., Bishop, M. D., & Cleland, J. A. (2010) · Physical Therapy · doi:10.2522/ptj.20090306 · Cited by 219
Depression after spinal cord injury: comorbidities, mental health service use, and adequacy of treatment
Fann, J. R., Bombardier, C. H., Richards, J. S., Tate, D. G., Wilson, C. S., & Temkin, N. (2011) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2010.05.016 · Cited by 205
Relationships of Fear, Anxiety, and Depression With Physical Function in Patients With Knee Osteoarthritis
Scopaz, K. A., Piva, S. R., Wisniewski, S. R., & Fitzgerald, G. K. (2009) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2009.06.012 · Cited by 206
Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression
Descalzi, G., Mitsi, V., Purushothaman, I., Gaspari, S., Avrampou, K., Loh, Y.-H. E., Shen, L., & Zachariou, V. (2017) · Science Signaling · doi:10.1126/scisignal.aaj1549 · Cited by 188
Operating Characteristics of PROMIS Four-Item Depression and Anxiety Scales in Primary Care Patients with Chronic Pain
Kroenke, K., Yu, Z., Wu, J., Kean, J., & Monahan, P. O. (2014) · Pain Medicine · doi:10.1111/pme.12537 · Cited by 187
Self-citation
Longitudinal association between pain, and depression and anxiety over four years
Gerrits, M. M. J. G., van Marwijk, H. W. J., van Oppen, P., van der Horst, H., & Penninx, B. W. J. H. (2015) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2014.10.011 · Cited by 172
Persistent pain and comorbidity among Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn veterans
Higgins, D. M., Kerns, R. D., Brandt, C. A., Haskell, S. G., Bathulapalli, H., Gilliam, W., & Goulet, J. L. (2014) · Pain Medicine · doi:10.1111/pme.12388 · Cited by 168
Self-compassion in patients with persistent musculoskeletal pain: relationship of self-compassion to adjustment to persistent pain
Wren, A. A., Somers, T. J., Wright, M. A., Goetz, M. C., Leary, M. R., Fras, A. M., Huh, B. K., Rogers, L. L., & Keefe, F. J. (2012) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2011.04.014 · Cited by 173
Musculoskeletal pain and exercise—Challenging existing paradigms and introducing new
Smith, B. E., Hendrick, P., Bateman, M., Holden, S., Littlewood, C., Smith, T. O., & Logan, P. (2019) · British Journal of Sports Medicine · doi:10.1136/bjsports-2017-098983 · Cited by 166
Chronic Pain in the Japanese Community—Prevalence, Characteristics and Impact on Quality of Life
Inoue, S., Kobayashi, F., Nishihara, M., Arai, Y.-C. P., Ikemoto, T., Kawai, T., Inoue, M., Hasegawa, T., & Ushida, T. (2015) · PLoS ONE · doi:10.1371/journal.pone.0129262 · Cited by 159
Resounding Meaning: A PERMA Wellbeing Profile of Classical Musicians
Ascenso, S., Perkins, R., & Williamon, A. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.01895 · Cited by 169
Elevated burnout predicts the onset of musculoskeletal pain among apparently healthy employees.
Armon, G., Melamed, S., Shirom, A., & Shapira, I. (2010) · Journal of Occupational Health Psychology · doi:10.1037/a0020726 · Cited by 143
Allodynia in Migraine: Association With Comorbid Pain Conditions
Tietjen, G. E., Brandes, J. L., Peterlin, B. L., Eloff, A., Dafer, R. M., Stein, M. R., Drexler, E. D., Martin, V. T., Hutchinson, S. L., Aurora, S. K., et al. (2009) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2009.01521.x · Cited by 137
Are depression, anxiety and poor mental health risk factors for knee pain? A systematic review
Phyomaung, P. P., Dubowitz, J., Cicuttini, F. M., Fernando, S., Wluka, A. E., Raaijmaakers, P., Wang, Y., & Urquhart, D. M. (2014) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-15-10 · Cited by 135
Symptoms of anxiety and depression among Norwegian musicians compared to the general workforce
Vaag, J. R., Bjø‌rngaard, J. H., & Bjerkeset, O. A. (2015) · Psychology of Music · doi:10.1177/0305735614564910 · Cited by 164
Psychiatric Comorbidity Is Associated Prospectively with Diminished Opioid Analgesia and Increased Opioid Misuse in Patients with Chronic Low Back Pain
Wasan, A. D., Michna, E., Edwards, R. R., Katz, J. N., Nedeljković, S. S., Dolman, A. J., Janfaza, D. R., Isaac, Z., & Jamison, R. N. (2015) · Anesthesiology · doi:10.1097/aln.0000000000000768 · Cited by 134
Self‐reported pain interference and symptoms of anxiety and depression in community‐dwelling older adults: Can a temporal relationship be determined?
Arola, H., Nicholls, E. E., Mallen, C. D., & Thomas, E. (2010) · European Journal of Pain · doi:10.1016/j.ejpain.2010.02.012 · Cited by 132
Advancing a National Agenda to Eliminate Disparities in Pain Care: Directions for Health Policy, Education, Practice, and Research
Meghani, S. H., Polomano, R. C., Tait, R. C., Vallerand, A. H., Anderson, K. O., & Gallagher, R. M. (2012) · Pain Medicine · doi:10.1111/j.1526-4637.2011.01289.x · Cited by 124
Chronic low back pain and the risk of depression or anxiety symptoms: insights from a longitudinal twin study
Fernandez, M., Colodro-Conde, L., Hartvigsen, J., Ferreira, M. L., Refshauge, K. M., Pinheiro, M. B., Ordoñana, J. R., & Ferreira, P. H. (2017) · The Spine Journal · doi:10.1016/j.spinee.2017.02.009 · Cited by 115
The Utility of the Short Version of the Depression Anxiety Stress Scales (DASS-21) in Elderly Patients with Persistent Pain: Does Age Make a Difference?
Wood, B. M., Nicholas, M. K., Blyth, F., Asghari, A., & Gibson, S. J. (2010) · Pain Medicine · doi:10.1111/j.1526-4637.2010.01005.x · Cited by 108
Evaluation of wet-cupping therapy for persistent non-specific low back pain: a randomised, waiting-list controlled, open-label, parallel-group pilot trial
Kim, J., Kim, T., Lee, M. S., Kang, J. W., Kim, K. H., Choi, J., Kang, K., Kim, A., Shin, M., Jung, S., et al. (2011) · Trials · doi:10.1186/1745-6215-12-146 · Cited by 109
Efficacy and Safety of Duloxetine on Osteoarthritis Knee Pain: A Meta-Analysis of Randomized Controlled Trials
Wang, Z. Y., Shi, S. Y., Li, S. J., Chen, F., Huang, C., Lin, H., & Lin, J. (2015) · Pain Medicine · doi:10.1111/pme.12800 · Cited by 104
Anxiety and Depression Are Associated With Migraine and Pain in General: An Investigation of the Interrelationships
Ligthart, L., Gerrits, M. M. J. G., Boomsma, D. I., & Penninx, B. W. J. H. (2013) · Journal of Pain · doi:10.1016/j.jpain.2012.12.006 · Cited by 107
Psychiatric Disorders Among Patients Seeking Treatment for Co-Occurring Chronic Pain and Opioid Use Disorder
Barry, D. T., Cutter, C. J., Beitel, M., Kerns, R. D., Liong, C., & Schottenfeld, R. S. (2016) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15m09963 · Cited by 104
Pain Among Cancer Survivors
Gallaway, M. S., Townsend, J. S., Shelby, D., & Puckett, M. (2020) · Preventing Chronic Disease · doi:10.5888/pcd17.190367 · Cited by 102
Positive emotions and brain reward circuits in chronic pain
Navratilova, E., Morimura, K., Xie, J. Y., Atcherley, C. W., Ossipov, M. H., & Porreca, F. (2016) · The Journal of Comparative Neurology · doi:10.1002/cne.23968 · Cited by 100
Depression as a prognostic factor of lumbar spinal stenosis: a systematic review.
McKillop, A., Carroll, L., & Battié, M. (2014) · The spine journal · doi:10.1016/j.spinee.2013.09.052 · Cited by 97
Beneficial Effects of Improvement in Depression, Pain Catastrophizing, and Anxiety on Pain Outcomes: A 12-Month Longitudinal Analysis
Scott, E. L., Kroenke, K., Wu, J., & Yu, Z. (2016) · The Journal of Pain · doi:10.1016/j.jpain.2015.10.011 · Cited by 98
Self-citation
Central sensitization and the biopsychosocial approach to understanding pain
Adams, L. M., & Turk, D. C. (2018) · Journal of Applied Biobehavioral Research · doi:10.1111/jabr.12125 · Cited by 99
Comorbidity Between Depression and Anxiety in Patients with Temporomandibular Disorders According to the Research Diagnostic Criteria for Temporomandibular Disorders
Reiter, S., Emodi‐Perlman, A., Goldsmith, C., Friedman-Rubin, P., & Winocur, E. (2015) · Journal of Oral & Facial Pain and Headache · doi:10.11607/ofph.1297 · Cited by 95
Pain/Depression Dyad: A Key to a Better Understanding and Treatment of Functional Somatic Syndromes
Goldenberg, D. L. (2010) · The American Journal of Medicine · doi:10.1016/j.amjmed.2010.01.014 · Cited by 94
The Impact of Anxiety and Depression on the Outcomes of Chronic Low Back Pain Multidisciplinary Pain Management—A Multicenter Prospective Cohort Study in Pain Clinics with One-Year Follow-up
Oliveira, D. S., Mendonça, L., Sampaio, R., Castro‐Lopes, J. M., & Azevedo, L. F. (2018) · Pain Medicine · doi:10.1093/pm/pny128 · Cited by 93
The Use of Wet Cupping for Persistent Nonspecific Low Back Pain: Randomized Controlled Clinical Trial
Al-Bedah, A. M., Khalil, M., El-Olemy, A. T., Hussein, A. A., Alqaed, M. S., Almudaiheem, A., Abutalib, R. A., Bazaid, F. M., Bafail, A. S., Essa, A., et al. (2015) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2015.0065 · Cited by 97
Obstetric pain correlates with postpartum depression symptoms: a pilot prospective observational study
Lim, G., LaSorda, K. R., Farrell, L. M., McCarthy, A. M., Facco, F., & Wasan, A. D. (2020) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-020-02943-7 · Cited by 89
Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain
Zhang, M., Liu, S., Chen, T., Koga, K., Zhang, T., Li, Y.-Q., & Zhuo, M. (2014) · Molecular Brain · doi:10.1186/1756-6606-7-47 · Cited by 94
nNOS-expressing neurons in the vmPFC transform pPVT-derived chronic pain signals into anxiety behaviors
Liang, H., Chen, Z., Xiao, H., Lin, Y., Hu, Y.-Y., Chang, L., Wu, H., Wang, P., Lu, W., Zhu, D., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16198-5 · Cited by 91
Environmental discomfort and musculoskeletal disorders
Magnavita, N., Elovainio, M. J., Nardis, I. D., Heponiemi, T., & Bergamaschi, A. (2011) · Occupational Medicine · doi:10.1093/occmed/kqr024 · Cited by 91
The association between pain catastrophising and kinesiophobia with pain and function in people with plantar heel pain
Cotchett, M., Lennecke, A., Medica, V. G., Whittaker, G. A., & Bonanno, D. R. (2017) · The Foot · doi:10.1016/j.foot.2017.03.003 · Cited by 86
Are sleep problems and non-specific health complaints risk factors for chronic pain? A prospective population-based study with 17 year follow-up
Nitter, A. K., Pripp, A. H., & Forseth, K. Ø. (2012) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2012.04.001 · Cited by 81
Biopsychosocial factors associated with chronic low back pain disability in rural Nigeria: a population-based cross-sectional study
Igwesi-Chidobe, C. N., Coker, B., Onwasigwe, C. N., Sorinola, I. O., & Godfrey, E. L. (2017) · BMJ Global Health · doi:10.1136/bmjgh-2017-000284 · Cited by 86
Depression and anxiety among chronic pain patients receiving prescription opioids and medical marijuana
Feingold, D., Brill, S., Goor‐Aryeh, I., Delayahu, Y., & Lev‐Ran, S. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.04.026 · Cited by 88
Changes in Anxiety and Depression Are Mediated by Changes in Pain Severity in Patients Undergoing Lower-Extremity Total Joint Arthroplasty
Hassett, A. L., Marshall, E., Bailey, A. M., Moser, S. E., Clauw, D. J., Hooten, W. M., Urquhart, A. G., & Brummett, C. M. (2017) · Regional Anesthesia & Pain Medicine · doi:10.1097/aap.0000000000000682 · Cited by 80
Examining the role of positive and negative affect in recovery from spine surgery
Seebach, C. L., Kirkhart, M., Lating, J. M., Wegener, S. T., Song, Y., Riley, L. H., & Archer, K. R. (2012) · Pain · doi:10.1016/j.pain.2011.10.012 · Cited by 77
Assessment of proximal outcomes of self-management programs: translation and psychometric evaluation of a German version of the Health Education Impact Questionnaire (heiQ™)
Schuler, M., Musekamp, G., Faller, H., Ehlebracht-König, I., Gutenbrunner, C., Kirchhof, R., Bengel, J., Nolte, S., Osborne, R. H., & Schwarze, M. (2013) · Quality of Life Research · doi:10.1007/s11136-012-0268-6 · Cited by 77
An Update on Repetitive Transcranial Magnetic Stimulation for the Treatment of Co-morbid Pain and Depressive Symptoms
Hsu, J. H., Daskalakis, Z. J., & Blumberger, D. M. (2018) · Current Pain and Headache Reports · doi:10.1007/s11916-018-0703-7 · Cited by 78
Relieving Pain in America
Loeser, J. D. (2012) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e318230f6c1 · Cited by 80
Determinants of Pain in Patients with Carpal Tunnel Syndrome
Nuñez, F. A., Vranceanu, A., & Ring, D. (2010) · Clinical Orthopaedics and Related Research · doi:10.1007/s11999-010-1551-x · Cited by 76
Responsiveness of the Michigan Hand Outcomes Questionnaire and the Disabilities of the Arm, Shoulder, and Hand Questionnaire in Patients With Hand Injury
Horng, Y.-S., Lin, M.-C., Feng, C.-T., Huang, C.-H., Wu, H.-C., & Wang, J. (2010) · The Journal Of Hand Surgery · doi:10.1016/j.jhsa.2009.11.016 · Cited by 76
How a Better Understanding of Spontaneous Mental Imagery Linked to Pain Could Enhance Imagery-Based Therapy in Chronic Pain
Berna, C., Tracey, I., & Holmes, E. A. (2012) · Journal of Experimental Psychopathology · doi:10.5127/jep.017911 · Cited by 77
The importance of fear, beliefs, catastrophizing and kinesiophobia in chronic low back pain rehabilitation
Thomas, E., Pers, Y., Mercier, G., Cambiere, J.-P., Frasson, N. C., Ster, F., Hérisson, C., & Blotman, F. (2009) · Annals of Physical and Rehabilitation Medicine · doi:10.1016/j.rehab.2009.11.002 · Cited by 75
Pain and mortality: mechanisms for a relationship
Smith, D. L., Wilkie, R., Croft, P. R., Parmar, S., & McBeth, J. (2018) · Pain · doi:10.1097/j.pain.0000000000001193 · Cited by 77
Preparation, Confidence, and Attitudes About Chronic Noncancer Pain in Graduate Medical Education
Yanni, L., Ketchum, J. M., Harrington, S. B., Huynh, C., Amin, B. S., Matsuyama, R. K., Coyne, P. J., Johnson, B. A., Fagan, M. J., & Garufi-Clark, L. (2010) · Journal of Graduate Medical Education · doi:10.4300/jgme-d-10-00006.1 · Cited by 73
Rasch analysis supports the use of the Depression, Anxiety, and Stress Scales to measure mood in groups but not in individuals with chronic low back pain
Parkitny, L., McAuley, J. H., Walton, D. M., Costa, L. O. P., Refshauge, K. M., Wand, B. M., Pietro, F. D., & Moseley, G. L. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.05.010 · Cited by 84
Anxiety and Fear-Avoidance in Musculoskeletal Pain
Lucchetti, G., Oliveira, A. B., Mercante, J. P. P., & Peres, M. F. P. (2012) · Current Pain and Headache Reports · doi:10.1007/s11916-012-0286-7 · Cited by 74
The association between severity of depression and prescription opioid misuse among chronic pain patients with and without anxiety: A cross-sectional study
Feingold, D., Brill, S., Goor-Aryeh, I., Delayahu, Y., & Lev-Ran, S. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.04.058 · Cited by 69
Implications of Preoperative Depression for Lumbar Spine Surgery Outcomes
Javeed, S., Benedict, B. C., Yakdan, S. M., Saleem, S., Zhang, J. K., Botterbush, K. S., Frumkin, M. R., Hardi, A., Neuman, B. J., Kelly, M. P., et al. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.48565 · Cited by 76
Prevalence of chronic musculoskeletal disorders in elderly Brazilians: a systematic review of the literature
Miranda, V. S., deCarvalho, V. B., Machado, L. A. C., & Dias, J. M. D. (2012) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-13-82 · Cited by 74
The influence of psychological factors on pre-operative levels of pain intensity, disability and health-related quality of life in lumbar spinal fusion surgery patients
Abbott, A. D., Tyni‐Lenné, R., & Hedlund, R. (2010) · Physiotherapy · doi:10.1016/j.physio.2009.11.013 · Cited by 70
Medical and Scientific Bases of Wet Cupping Therapy (Al-hijamah): in Light of Modern Medicine and Prophetic Medicine
HS, E. S. S. M. (2013) · Alternative & Integrative Medicine · doi:10.4172/2327-5162.1000122 · Cited by 69
Understanding pain and depression in back pain: the role of catastrophizing, help-/hopelessness, and thought suppression as potential mediators
Hülsebusch, J., Hasenbring, M. I., & Rusu, A. C. (2016) · International Journal of Behavioral Medicine · doi:10.1007/s12529-015-9522-y · Cited by 68
Depression, Anxiety, and Stress in People With and Without Plantar Heel Pain
Cotchett, M., Munteanu, S. E., & Landorf, K. B. (2016) · Foot & Ankle International · doi:10.1177/1071100716646630 · Cited by 68
Medically Unexplained and Explained Physical Symptoms in the General Population: Association with Prevalent and Incident Mental Disorders
van der Sluijs, J. V. E., ten Have, M., Rijnders, C. A. T., van Marwijk, H., de Graaf, R., & Feltz-Cornelis, C. M. V. D. (2015) · PLoS ONE · doi:10.1371/journal.pone.0123274 · Cited by 66
Psychosocial stress and anxiety in musculoskeletal pain patients with and without depression
Poleshuck, E. L., Bair, M. J., Kroenke, K., Damush, T. M., Tu, W., Wu, J., Krebs, E. E., & Giles, D. E. (2008) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2008.10.003 · Cited by 67
Self-citation
Effects of Monoamine Reuptake Inhibitors in Assays of Acute Pain-Stimulated and Pain-Depressed Behavior in Rats
Rosenberg, M., Carroll, F. I., & Negus, S. S. (2013) · Journal of Pain · doi:10.1016/j.jpain.2012.11.006 · Cited by 65
Cognitive behavioural therapy in pain and psychological disorders: Towards a hybrid future
Tang, N. K. Y. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.02.023 · Cited by 68
Stepped Care to Optimize Pain Care Effectiveness (SCOPE) trial: study design and sample characteristics
Kroenke, K., Krebs, E., Wu, J., Bair, M. J., Damush, T., Chumbler, N., York, T., Weitlauf, S., McCalley, S., Evans, E., et al. (2013) · Contemporary Clinical Trials · doi:10.1016/j.cct.2012.11.008 · Cited by 63
Self-citation
NIH-DoD-VA Pain Management Collaboratory
Kerns, R. D., Brandt, C., & Peduzzi, P. N. (2019) · Pain Medicine · doi:10.1093/pm/pnz186 · Cited by 63
Quality of life, physical functioning, and psychosocial function among patients with achondroplasia : a targeted literature review
Constantinides, C. A., Landis, S., Jarrett, J., Quinn, J., & Ireland, P. J. (2021) · Disability and Rehabilitation · doi:10.1080/09638288.2021.1963853 · Cited by 63
Psychiatric problems in fibromyalgia: clinical and neurobiological links between mood disorders and fibromyalgia
Alciati, A., Sgiarovello, P., Atzeni, F., & Sarzi‐Puttini, P. (2012) · Reumatismo · doi:10.4081/reumatismo.2012.268 · Cited by 63
Anxiety but Not Social Stressors Predict 12-Month Depression and Pain Severity
Bair, M. J., Poleshuck, E. L., Wu, J., Krebs, E. E., Damush, T. M., Tu, W., & Kroenke, K. (2012) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e3182652ee9 · Cited by 71
Self-citation
Pain in chemotherapy-induced neuropathy – More than neuropathic?
Geber, C., Breimhorst, M., Burbach, B., Egenolf, C., Baier, B., Fechir, M., Koerber, J., Treede, R., VOGT, T. M., & Birklein, F. (2013) · Pain · doi:10.1016/j.pain.2013.08.028 · Cited by 63
The Role of Perceived Stress and Life Stressors in the Development of Chronic Musculoskeletal Pain Disorders: A Systematic Review
Buscemi, V., Chang, W., Liston, M. B., McAuley, J. H., & Schabrun, S. M. (2019) · Journal of Pain · doi:10.1016/j.jpain.2019.02.008 · Cited by 72
Comorbidade de sintomas ansiosos e depressivos em pacientes com dor crônica e o impacto sobre a qualidade de vida
Castro, M. M. C., Quarantini, L. C., Daltro, C., Caldas, M. P., Koenen, K. C., Kraychete, D. C., & de Oliveira, I. R. (2011) · Archives of Clinical Psychiatry (São Paulo) · doi:10.1590/s0101-60832011000400002 · Cited by 59
Association of Anxiety and Depression With Pain and Quality of Life in Patients With Chronic Foot and Ankle Diseases
Nakagawa, R., Yamaguchi, S., Kimura, S., Sadamasu, A., Yamamoto, Y., Sato, Y., Akagi, R., Sasho, T., & Ohtori, S. (2017) · Foot & Ankle International · doi:10.1177/1071100717723133 · Cited by 59
Pain interference and incident mood, anxiety, and substance-use disorders: Findings from a representative sample of men and women in the general population
Barry, D. T., Pilver, C. E., Hoff, R. A., & Potenza, M. N. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.08.004 · Cited by 59
Psychological variables associated with foot function and foot pain in patients with plantar heel pain
Cotchett, M. P., Whittaker, G., & Erbas, B. (2015) · Clinical Rheumatology · doi:10.1007/s10067-014-2565-7 · Cited by 52
The efficacy of percutaneous vertebroplasty for vertebral metastases associated with solid malignancies
Lee, B., Franklin, I., Lewis, J. S., Coombes, R. C., Leonard, R. C., Gishen, P., & Stebbing, J. (2009) · European Journal of Cancer · doi:10.1016/j.ejca.2009.01.021 · Cited by 59
Iatrogenic opioid use disorder, chronic pain and psychiatric comorbidity: A systematic review
van Rijswijk, S. M., Beek, M. H. C. T. V., Schoof, G. M., Schene, A. H., Steegers, M. A. H., & Schellekens, A. (2019) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2019.04.008 · Cited by 63
Unilateral facial injection of Botulinum neurotoxin A attenuates bilateral trigeminal neuropathic pain and anxiety-like behaviors through inhibition of TLR2-mediated neuroinflammation in mice
Chen, W., Niu, J.-Q., Chen, Y., Deng, W.-J., Xu, Y., Liu, J., Luo, W., & Liu, T. (2021) · The Journal of Headache and Pain · doi:10.1186/s10194-021-01254-2 · Cited by 60
New Concepts in Pain Research and Pain Management of the Rheumatic Diseases
Goldenberg, D. L., Clauw, D. J., & Fitzcharles, M. (2011) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2011.04.005 · Cited by 58
Depression and pain impair daily functioning and quality of life in patients with major depressive disorder
Lin, C.-H., Yen, Y.-C., Chen, M.-C., & Chen, C.-C. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.03.039 · Cited by 57
Substituting Cannabidiol for Opioids and Pain Medications Among Individuals With Fibromyalgia: A Large Online Survey
Boehnke, K. F., Gagnier, J. J., Matallana, L. K., & Williams, D. A. (2021) · Journal of Pain · doi:10.1016/j.jpain.2021.04.011 · Cited by 56
The importance of psychological assessment in chronic pain
Williams, D. A. (2013) · Current Opinion in Urology · doi:10.1097/mou.0b013e3283652af1 · Cited by 65
Clinical Uses of Intrathecal Therapy and Its Placement in the Pain Care Algorithm
Pope, J. E., Deer, T. R., Bruel, B. M., & Falowski, S. M. (2016) · Pain Practice · doi:10.1111/papr.12438 · Cited by 56
The relationship between psychosocial factors and reported disability: the role of pain self-efficacy
Varela, A. J., & van Asselt, K. W. (2022) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-021-04955-6 · Cited by 63
Chronic Tension‐Type Headache With Vitamin D Deficiency: Casual or Causal Association?
Prakash, S., & Shah, N. D. (2009) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2009.01483.x · Cited by 55
Low- and high-anxious hypermobile Ehlers–Danlos syndrome patients: comparison of psychosocial and health variables
Baeza-Velasco, C., Bourdon, C., Montalescot, L., de Cazotte, C., Pailhez, G., Bulbena, A., & Hamonet, C. (2018) · Rheumatology International · doi:10.1007/s00296-018-4003-7 · Cited by 54
Pain Scores among Emergency Department (ED) Patients: Comparison by ED Diagnosis
Marco, C. A., Kanitz, W., & Jolly, M. (2012) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2012.05.002 · Cited by 53

Authors: Bair, M. J., Wu, J., Damush, T. M., Sutherland, J. M., & Kroenke, K.
Affiliations: Richard L. Roudebush VA Medical Center (US)
Dartmouth College (US)
Corresponding author: Bair, Matthew J.
ORCID: Bair, Matthew J.
Wu, Jingwei
Damush, Teresa M.
Sutherland, Jason M.
Kroenke, Kurt
Venue: Psychosomatic Medicine
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2008-10
Volume: 70
Issue: 8
Pages: 890-897
ISSN: 0033-3174 (ISSN-L)
DOI: 10.1097/psy.0b013e318185c510
PMC: PMC2902727
OpenAlex: W2049101564
Cited by: 572
References: 75
Citations by year: 2026: 25 · 2025: 25 · 2024: 36 · 2023: 26 · 2022: 33 · 2021: 48 · 2020: 42 · 2019: 42 · 2018: 37 · 2017: 32 · 2016: 28 · 2015: 43 · 2014: 35 · 2013: 29 · 2012: 22
FWCI: 15.94
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Psychosomatic Medicine (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
IUScholarWorks (Indiana University) (submittedVersion)
Funders: National Institute of Mental Health (MH 071268, R01MH071268)
Topics: Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords: depression, anxiety, psychiatric comorbidity, pain intensity, pain-related disability, health-related quality of life, low back pain, hip pain, knee pain, primary care
MeSH terms: Absenteeism, Adult, Aged, Antidepressive Agents, Anxiety Disorders, Behavior Therapy, Chronic Disease, Combined Modality Therapy, Cross-Sectional Studies, Depressive Disorder, Disability Evaluation, Female, Humans, Male, Middle Aged, Pain, Pain Measurement, Primary Health Care, Prospective Studies, Quality of Life, Self Care, Sick Role, Social Behavior, Cohort Studies, Comorbidity, Self Efficacy, Pain Management

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Association of Depression and Anxiety Alone and in Combination With Chronic Musculoskeletal Pain in Primary Care Patients

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks