The DOI matches its Crossref record; 138 of the 138 references it cites were found in a registry or an index.
Advances in multicellular spheroids formation
Open accessAbstract
Three-dimensional multicellular spheroids (MCSs) have a complex architectural structure, dynamic cell–cell/cell–matrix interactions and bio-mimicking in vivo microenvironment. As a fundamental building block for tissue reconstruction, MCSs have emerged as a powerful tool to narrow down the gap between the in vitro and in vivo model. In this review paper, we discussed the structure and biology of MCSs and detailed fabricating methods. Among these methods, the approach in microfluidics with hydrogel support for MCS formation is promising because it allows essential cell–cell/cell–matrix interactions in a confined space.
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Cites
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Cited by
Nunes, A. S., Barros, A. S., Costa, E. C., Moreira, A. F., & Correia, I. J. (2019) · Biotechnology and Bioengineering · doi:10.1002/bit.26845 · Cited by 721
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Metadata
- Authors
- Cui, X., Hartanto, Y., & Zhang, H.
- Venue
- Journal of The Royal Society Interface
- Publisher
- The Royal Society
- Published
- 2017-02
- Volume
- 14
- Issue
- 127
- Pages
- 20160877
- ISSN
- 1742-5662 (ISSN-L)
- 1742-5689
- OpenAlex
- W2588271989
- Cited by
- 508
- References
- 138
- FWCI
- 17.11
- Type
- journal article
- Language
- en
- Open access
- green
- Licence
- royalsociety.org/journals/ethics-policies/data-sharing-mining/ (tdm)
- Funders
- Medical Advances Without Animals Trust
- Australian Research Council (DP160104632)
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
