Are stress responses to geomagnetic storms mediated by the cryptochrome compass system?
Open accessAbstract
A controversial body of literature demonstrates associations of geomagnetic storms (GMS) with numerous cardiovascular, psychiatric and behavioural outcomes. Various melatonin hypotheses of GMS have suggested that temporal variation in the geomagnetic field (GMF) may be acting as an additional zeitgeber (a temporal synchronizer) for circadian rhythms, with GMS somehow interfering with the hypothesized system. The cryptochrome genes are known primarily as key components of the circadian pacemaker, ultimately involved in controlling the expression of the hormone melatonin. Cryptochrome is identified as a clear candidate for mediating the effect of GMS on humans, demonstrating the prior existence of several crucial pieces of evidence. A distinct scientific literature demonstrates the widespread use of geomagnetic information for navigation across a range of taxa. One mechanism of magnetoreception is thought to involve a light-dependent retinal molecular system mediated by cryptochrome, acting in a distinct functionality to its established role as a circadian oscillator. There is evidence suggesting that such a magnetosense—or at least the vestiges of it—may exist in humans. This paper argues that cryptochrome is not acting as secondary geomagnetic zeitgeber to influence melatonin synthesis. Instead, it is hypothesized that the cryptochrome compass system is mediating stress responses more broadly across the hypothalamic–pituitary–adrenal (HPA) axis (including alterations to circadian behaviour) in response to changes in the GMF. Two conceptual models are outlined for the existence of such responses—the first as a generalized migrational/dispersal strategy, the second as a stress response to unexpected signals to the magnetosense. It is therefore proposed that GMS lead to disorientation of hormonal systems in animals and humans, thus explaining the effects of GMS on human health and behaviour.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Graphene quantum dots have been shown to prevent and even undo the protein clumping of neurons in the brain that leads to Parkinson's disease.
“Even more recently, graphene quantum dots have been shown to prevent and even undo the protein clumping of neurons in the brain that leads to Parkinson's disease 211 .”
From Quantum effects in the brain: A review (2020) · cites this paper as [211]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
1 retracted
Correlation between heart attacks and magnetic activity—a retraction
Malin, S. R. C., & Srivastava, B. J. (1980) · Nature · doi:10.1038/283111c0 · Cited by 12 · see citing works
RetractedStress and disorders of the stress system
Chrousos, G. P. (2009) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2009.106 · Cited by 3,215 · see citing works
A Model for Photoreceptor-Based Magnetoreception in Birds
Ritz, T., Adem, S., & Schulten, K. (2000) · Biophysical Journal · doi:10.1016/s0006-3495(00)76629-x · Cited by 1,176 · see citing works
Structure and function of the vertebrate magnetic sense
Walker, M. M., Diebel, C. E., Haugh, C. V., Pankhurst, P. M., Montgomery, J. C., & Green, C. R. (1997) · Nature · doi:10.1038/37057 · Cited by 444 · see citing works
A Biomagnetic Sensory Mechanism Based on Magnetic Field Modulated Coherent Electron Spin Motion
Schulten, K., Swenberg, C. E., & Weller, A. (1978) · Zeitschrift für Physikalische Chemie · doi:10.1524/zpch.1978.111.1.001 · Cited by 430 · see citing works
Melanopsin: an exciting photopigment
Hankins, M. W., Peirson, S. N., & Foster, R. G. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2007.11.002 · Cited by 426 · see citing works
Cryptochrome mediates light-dependent magnetosensitivity in Drosophila
Gegear, R. J., Casselman, A., Waddell, S., & Reppert, S. M. (2008) · Nature · doi:10.1038/nature07183 · Cited by 421 · see citing works
Reiter, R. J. (2003) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/s1521-690x(03)00016-2 · Cited by 338 · see citing works
The origins of sedentism and farming communities in the Levant
Bar-Yosef, O., & Belfer-Cohen, A. (1989) · Journal of World Prehistory · doi:10.1007/bf00975111 · Cited by 338 · see citing works
Mouritsen, H., Janssen‐Bienhold, U., Liedvogel, M., Feenders, G., Stalleicken, J., Dirks, P., & Weiler, R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405968101 · Cited by 304 · see citing works
Welker, H. A., Semm, P., Willig, R. P., Commentz, J. C., Wiltschko, W., & Vollrath, L. (1983) · Experimental Brain Research · doi:10.1007/bf00239209 · Cited by 284 · see citing works
Melatonin in Psychiatric Disorders: A Review on the Melatonin Involvement in Psychiatry
Pacchierotti, C., Iapichino, S., Bossini, L., Pieraccini, F., & Castrogiovanni, P. (2001) · Frontiers in Neuroendocrinology · doi:10.1006/frne.2000.0202 · Cited by 235 · see citing works
Melatonin and circadian biology in human cardiovascular disease
Domínguez‐Rodríguez, A., Abreu-González, P., Sanchez-Sanchez, J. J., Kaski, J. C., & Reiter, R. J. (2010) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2010.00773.x · Cited by 232 · see citing works
Cryptochrome Mediates Light-Dependent Magnetosensitivity of Drosophila's Circadian Clock
Yoshii, T., Ahmad, M., & Helfrich-Förster, C. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000086 · Cited by 232 · see citing works
Cryptochromes—a potential magnetoreceptor: what do we know and what do we want to know?
Liedvogel, M., & Mouritsen, H. (2010) · Journal of The Royal Society Interface · doi:10.1098/rsif.2009.0411.focus · Cited by 231 · see citing works
Human cryptochrome exhibits light-dependent magnetosensitivity
Foley, L. E., Gegear, R. J., & Reppert, S. M. (2011) · Nature Communications · doi:10.1038/ncomms1364 · Cited by 214 · see citing works
Temperature Synchronization of the Drosophila Circadian Clock
Glaser, F. T., & Stanewsky, R. (2005) · Current Biology · doi:10.1016/j.cub.2005.06.056 · Cited by 211 · see citing works
Palmer, S. J., RYCROFT, M. J., & Cermack, M. (2006) · Surveys in Geophysics · doi:10.1007/s10712-006-9010-7 · Cited by 208 · see citing works
Schumann Resonances, a plausible biophysical mechanism for the human health effects of Solar
Cherry, N. J. (2002) · Natural Hazards · doi:10.1023/a:1015637127504 · Cited by 194 · see citing works
Non-photic solar associations of heart rate variability and myocardial infarction
Cornélissen, G., Franz Halberg, A., Breus, T. K., Syutkina, E. V., Baevsky, R. M., Weydahl, A., Watanabe, Y., Otsuka, K., Siègelovà, J., Fišer, B., et al. (2002) · Journal of Atmospheric and Solar-Terrestrial Physics · doi:10.1016/s1364-6826(02)00032-9 · Cited by 194 · see citing works
Normal fluctuations in the earth's magnetic field influence pigeon orientation
Keeton, W. T., Larkin, T. S., & Windsor, D. M. (1974) · Journal of Comparative Physiology A · doi:10.1007/bf00610108 · Cited by 186 · see citing works
Reiter, R. J. (1993) · Journal of Cellular Biochemistry · doi:10.1002/jcb.2400510403 · Cited by 159 · see citing works
CRY2 Is Associated with Depression
Lavebratt, C., Sjöholm, L. K., Soronen, P., Paunio, T., Vawter, M. P., Bunney, W. E., Adolfsson, R., Forsell, Y., Wu, J. C., Kelsoe, J. R., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009407 · Cited by 155 · see citing works
Semm, P., Nohr, D., Demaine, C., & Wiltschko, W. (1984) · Journal of Comparative Physiology A · doi:10.1007/bf00610581 · Cited by 142 · see citing works
Beneficial effects of melatonin in cardiovascular disease
Reiter, R. J., Tan, D., Paredes, S. D., & Fuentes‐Broto, L. (2010) · Annals of Medicine · doi:10.3109/07853890903485748 · Cited by 142 · see citing works
Burch, J. B., Reif, J. S., & Yost, M. G. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(99)00308-0 · Cited by 138 · see citing works
The adrenal peripheral clock: Glucocorticoid and the circadian timing system
Son, G. H., Chung, S., & Kim, K. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2011.07.003 · Cited by 136 · see citing works
Physiological, behavioral, and ecological aspects of migration in reptiles
Southwood, A. L., & Avens, L. (2009) · Journal of Comparative Physiology B · doi:10.1007/s00360-009-0415-8 · Cited by 123 · see citing works
Olcese, J., Reuss, S., & Vollrath, L. (1985) · Brain Research · doi:10.1016/0006-8993(85)91598-7 · Cited by 121 · see citing works
Extremely low-frequency electromagnetic fields disrupt magnetic alignment of ruminants
Burda, H., Begall, S., Červený, J., Neef, J., & Němec, P. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811194106 · Cited by 114 · see citing works
Geomagnetic Storms: Association with Incidence of Depression as Measured by Hospital Admission
Kay, R. W. (1994) · British Journal of Psychiatry · doi:10.1192/bjp.164.3.403 · Cited by 108 · see citing works
Extraocular magnetic compass in newts
Deutschlander, M. E., Borland, S., & Phillips, J. B. (1999) · Nature · doi:10.1038/22450 · Cited by 103 · see citing works
Circadian rhythms and clock genes in psychotic disorders.
Lamont, E. W., Coutu, D. L., Cermakian, N., & Boivin, D. B. (2010) · PubMed · Cited by 102 · see citing works
Reduced Excretion of a Melatonin Metabolite in Workers Exposed to 60 Hz Magnetic Fields
Burch, J. B., Reif, J. S., Yost, M. G., Keefe, T. J., & Pitrat, C. A. (1999) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009914 · Cited by 97 · see citing works
Medial vestibular connections with the hypocretin (orexin) system
Horowitz, S. S., Blanchard, J. H., & Morin, L. P. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20521 · Cited by 97 · see citing works
Phillips, J. B., Muheim, R., & Jorge, P. E. (2010) · Journal of Experimental Biology · doi:10.1242/jeb.020792 · Cited by 94 · see citing works
When brain clocks lose track of time: cause or consequence of neuropsychiatric disorders
Menet, J. S., & Rosbash, M. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.06.008 · Cited by 91 · see citing works
Olcese, J., & Reuss, S. (1986) · Brain Research · doi:10.1016/0006-8993(86)90552-4 · Cited by 90 · see citing works
Sudo, M., Sasahara, K., Moriya, T., Akiyama, M., Hamada, T., & Shibata, S. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00457-3 · Cited by 88 · see citing works
Geomagnetic activity influences the melatonin secretion at latitude 70° N
Weydahl, A., Sothern, R. B., Cornélissen, G., & Wetterberg, L. (2000) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(01)90006-x · Cited by 86 · see citing works
Influence of local geomagnetic storms on arterial blood pressure
Dimitrova, S., Stoilova, I., & Cholakov, I. (2004) · Bioelectromagnetics · doi:10.1002/bem.20009 · Cited by 83 · see citing works
Reiter, R. J. (1994) · Reviews on Environmental Health · doi:10.1515/reveh.1994.10.3-4.171 · Cited by 80 · see citing works
Bartsch, H., Bartsch, C., Mecke, D., & Lippert, T. H. (1994) · Chronobiology International · doi:10.3109/07420529409057227 · Cited by 78 · see citing works
Magnetic field effects on the rat pineal gland: Role of retinal activation by light
Reuss, S., & Olcese, J. (1986) · Neuroscience Letters · doi:10.1016/0304-3940(86)90670-1 · Cited by 78 · see citing works
Magnetic bones in human sinuses
Baker, R. R., Mather, J. G., & Kennaugh, J. H. (1983) · Nature · doi:10.1038/301078a0 · Cited by 74 · see citing works
Evidence of a nonlinear human magnetic sense
Carrubba, S., Frilot, C. F., II, Chesson, A. L., & Marino, A. A. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.068 · Cited by 72 · see citing works
Melatonin Metabolite Levels in Workers Exposed to 60-Hz Magnetic Fields:
Burch, J. B., Reif, J. S., Noonan, C. W., & Yost, M. G. (2000) · Journal of Occupational and Environmental Medicine · doi:10.1097/00043764-200002000-00006 · Cited by 72 · see citing works
The effect of geomagnetic activity on cardiovascular parameters
Stoupel, E. G. (2002) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(02)00299-8 · Cited by 71 · see citing works
Sheikh, M. S., Shao, Z., Chen, J., Hussain, A., Jetten, A. M., & Fontana, J. A. (1993) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240530417 · Cited by 67 · see citing works
Solar cycles and their relationship to human disease and adaptability
Davis, G. E., & Lowell, W. E. (2006) · Medical Hypotheses · doi:10.1016/j.mehy.2006.03.011 · Cited by 64 · see citing works
Persinger, M. A., & Psych, C. (1995) · International Journal of Biometeorology · doi:10.1007/bf01245386 · Cited by 61 · see citing works
Запорожан, В. М., & Ponomarenko, A. (2010) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph7030938 · Cited by 61 · see citing works
Expression of the Blue-Light Receptor Cryptochrome in the Human Retina
Thompson, C. L., Rickman, C. B., Shaw, S. J., Ebright, J. N., Kelly, U., Sancar, A., & Rickman, D. W. (2003) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.03-0303 · Cited by 60 · see citing works
Geomagnetic field effect on cardiovascular regulation
Gmitrov, J., & Gmitrova, A. (2004) · Bioelectromagnetics · doi:10.1002/bem.10173 · Cited by 58 · see citing works
Search for correlation between geomagnetic disturbances and mortality
Lipa, B., Sturrock, P. A., & Rogot, E. (1976) · Nature · doi:10.1038/259302a0 · Cited by 56 · see citing works
ELF magnetic fields: Animal studies, mechanisms of action
Lagroye, I., Percherancier, Y., Juutilainen, J., de Gannes, F. P., & Veyret, B. (2011) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2011.09.003 · Cited by 54 · see citing works
ELF-Effects on Human Circadian Rhythms
Wever, R. (1974) · Springer eBooks · doi:10.1007/978-1-4684-9004-6_5 · Cited by 53 · see citing works
Pineal sensitivity to pulsed static magnetic fields changes during the photoperiod
Yaga, K., Reiter, R. J., Manchester, L. C., Nieves, H., Jih-Hsing, S., & Li-Dun, C. (1993) · Brain Research Bulletin · doi:10.1016/0361-9230(93)90052-d · Cited by 53 · see citing works
Geomagnetic activity and human melatonin metabolite excretion
Burch, J. B., Reif, J. S., & Yost, M. G. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.04.031 · Cited by 52 · see citing works
Markia, B., Kovács, Z. I., & Palkovits, M. (2008) · Brain Structure and Function · doi:10.1007/s00429-008-0172-6 · Cited by 50 · see citing works
Stehle, J., Reuss, S., Schröder, H. C., Henschel, M., & Vollrath, L. (1988) · Physiology & Behavior · doi:10.1016/0031-9384(88)90350-2 · Cited by 49 · see citing works
Food availability but not melatonin affects nocturnal restlessness in a wild migrating passerine
Fusani, L., Cardinale, M., Schwabl, I., & Goymann, W. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.11.013 · Cited by 49 · see citing works
Heart attacks and geomagnetic activity
Knox, E. G., Armstrong, E., Lancashire, R. J., Wall, M., & Haynes, R. M. (1979) · Nature · doi:10.1038/281564a0 · Cited by 49 · see citing works
Booth, J. N., Koren, S. A., & Persinger, M. A. (2005) · International Journal of Neuroscience · doi:10.1080/00207450590901521 · Cited by 48 · see citing works
[Effect of geomagnetic activity on the functional status of the body].
Oraevskii, V. N., Breus, T. K., Баевский, Р. М., Рапопорт, С. И., Petrov, V. M., Barsukova, Z. V., Гурфинкель, Ю. И., & Rogoza, A. T. (1998) · PubMed · Cited by 47 · see citing works
Pc1 geomagnetic pulsations as a potential hazard of the myocardial infarction
Клейменова, Н. Г., Kozyreva, O. V., Breus, T. K., & Рапопорт, С. И. (2007) · Journal of Atmospheric and Solar-Terrestrial Physics · doi:10.1016/j.jastp.2006.10.018 · Cited by 45 · see citing works
Are solar activity and sperm whale Physeter macrocephalus strandings around the North Sea related?
Vanselow, K., & Ricklefs, K. (2005) · Journal of Sea Research · doi:10.1016/j.seares.2004.07.006 · Cited by 44 · see citing works
Burger, T., Lucová, M., Moritz, R. E., Oelschläger, H., Druga, R., Burda, H., Wiltschko, W., Wiltschko, R., & Němec, P. (2010) · Journal of The Royal Society Interface · doi:10.1098/rsif.2009.0551 · Cited by 44 · see citing works
Henshel, D. S. (1998) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5620170111 · Cited by 41 · see citing works
O'Connor, R. P., & Persinger, M. A. (1997) · Perceptual and Motor Skills · doi:10.2466/pms.1997.84.2.395 · Cited by 40 · see citing works
Entrainment of Circadian Activity Rhythms in Mice by Electrostatic Fields
Dowse, H. B., & Palmer, J. D. (1969) · Nature · doi:10.1038/222564a0 · Cited by 40 · see citing works
Oinuma, S., Kubo, Y., Otsuka, K., Yamanaka, T., Murakami, S., Matsuoka, O., Ohkawa, S.-I., Cornélissen, G., Weydahl, A., Holmeslet, B., et al. (2002) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(02)00303-7 · Cited by 38 · see citing works
Human navigation and magnetoreception: the Manchester experiments do replicate
Baker, R. R. (1987) · Animal Behaviour · doi:10.1016/s0003-3472(87)80105-7 · Cited by 32 · see citing works
Playing the Field: Geomagnetic Storms and the Stock MarketPreprint
Robotti, C., & Krivelyova, A. (2003) · SSRN Electronic Journal · doi:10.2139/ssrn.375702 · Cited by 32 · see citing works
Gould, J. L. (2010) · Current Biology · doi:10.1016/j.cub.2010.03.045 · Cited by 31 · see citing works
Magnetic storm effect on the circulation of rabbits
Chibisov, S. M., Cornélissen, G., & Halberg, F. (2004) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(04)80003-9 · Cited by 30 · see citing works
Effect of geomagnetic activity on cardiovascular parameters
Stoupel, E. G. (1999) · Journal für Kardiologie (Krause & Pachernegg GmbH) · Cited by 30 · see citing works
Kumlin, T., Heikkinen, P., Laitinen, J. T., & Juutilainen, J. (2005) · Journal of Radiation Research · doi:10.1269/jrr.46.313 · Cited by 28 · see citing works
Józsa, R., Franz Halberg, A., Cornélissen, G., Zeman, M., Kazsaki, J., CSERNUS, V. J., Katinas, G., Wendt, H., Othild Schwartzkopff, A., Stebelová, K., et al. (2005) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(05)80006-x · Cited by 28 · see citing works
[Magnetic storms as a stress factor].
Рапопорт, С. И., Td, B., Nk, M., Vn, O., Meshcheriakova, S. A., Tk, B., & Am, S. (1998) · PubMed · Cited by 28 · see citing works
Sienkiewicz, Z. J., Bartram, R., Haylock, R., & Saunders, R. D. (2000) · Bioelectromagnetics · doi:10.1002/1521-186x(200101)22:1 · Cited by 26 · see citing works
Stoupel, Ε., Petrauskienė, J., Abramson, E., Kalèdiené, R., & Sulkes, J. (2002) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(02)00306-2 · Cited by 26 · see citing works
Sunspot Dynamics Are Reflected in Human Physiology and Pathophysiology
Hrushesky, W. J. M., Sothern, R. B., Du‐Quiton, J., Quiton, D. F. T., Rietveld, W. J., & Boon, M. E. (2011) · Astrobiology · doi:10.1089/ast.2010.0574 · Cited by 25 · see citing works
Boström, J. E., Fransson, T., Henshaw, I., Jakobsson, S., Kullberg, C., & Åkesson, S. (2010) · Behavioral Ecology and Sociobiology · doi:10.1007/s00265-010-0985-1 · Cited by 24 · see citing works
Occupational magnetic field exposure and melatonin: Interaction with light‐at‐night
Juutilainen, J., & Kumlin, T. (2006) · Bioelectromagnetics · doi:10.1002/bem.20231 · Cited by 23 · see citing works
[Medico-biological effect of natural electromagnetic variations].
Oraevskii, V. N., Kuleshova, V. P., Gurfinkel, I. F., Guseva, A. V., & Рапопорт, С. И. (1998) · PubMed · Cited by 23 · see citing works
Magnetic Orientation in Migratory Songbirds
Deutschlander, M. E., & Muheim, R. (2010) · Elsevier eBooks · doi:10.1016/b978-0-08-045337-8.00363-6 · Cited by 23 · see citing works
The geomagnetic field influences the sensitivity of our eyes
Thoss, F., & Bartsch, B. (2007) · Vision Research · doi:10.1016/j.visres.2007.01.022 · Cited by 21 · see citing works
Stoupel, Ε., Monselise, Y., & Lahav, J. (2006) · Journal of Basic and Clinical Physiology and Pharmacology · doi:10.1515/jbcpp.2006.17.4.269 · Cited by 20 · see citing works
Engelmann, W., Hellrung, W., & Johnsson, A. (1996) · Bioelectromagnetics · doi:10.1002/(sici)1521-186x(1996)17:2 · Cited by 19 · see citing works
Henshaw, I., Fransson, T., Jakobsson, S., Jenni‐Eiermann, S., & Kullberg, C. (2009) · Journal of Experimental Biology · doi:10.1242/jeb.033332 · Cited by 19 · see citing works
Esquivel, D. M. S., Wajnberg, E., do Nascimento, F. S., Pinho, M. B., de Barros, H. G. P. L., & Eizemberg, R. (2006) · Die Naturwissenschaften · doi:10.1007/s00114-006-0169-z · Cited by 19 · see citing works
Рапопорт, С. И., Nk, M., Vn, O., Komarov, F. I., Nosovskiĭ, A. M., & Vetterberg, L. (1997) · PubMed · Cited by 17 · see citing works
Michon, A., Koren, S. A., & Persinger, M. A. (1996) · Perceptual and Motor Skills · doi:10.2466/pms.1996.82.2.619 · Cited by 16 · see citing works
O'Connor, R. P., & Persinger, M. A. (1996) · International Journal of Neuroscience · doi:10.3109/00207459609000617 · Cited by 15 · see citing works
Geophysical variables and human health and behavior
Stoilova, I., & Dimitrova, S. (2007) · Journal of Atmospheric and Solar-Terrestrial Physics · doi:10.1016/j.jastp.2007.08.053 · Cited by 15 · see citing works
Does magnetoreception mediate biological effects of power-frequency magnetic fields?
Vanderstraeten, J., & Burda, H. (2011) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2011.08.071 · Cited by 15 · see citing works
Magnetic Orientation in Migratory Songbirds
Deutschlander, M. E., Muheim, R., & Bairlein, F. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809633-8.90099-2 · Cited by 9 · see citing works
Weydahl, A., Sothern, R. B., & Cornélissen, G. (2002) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(02)00305-0 · Cited by 7 · see citing works
Solar activity during gestation does not affect human lifespan: evidence from national data
Helle, S. (2009) · Biogerontology · doi:10.1007/s10522-009-9214-6 · Cited by 5 · see citing works
Рапопорт, С. И., Smirnova, A. V., Nn, N., & Sp, G. (2007) · PubMed · Cited by 3 · see citing works
Glaciation due to continental drift
Reynolds, J. M. (1980) · Nature · doi:10.1038/283111d0 · Cited by 2 · see citing works
[Different methods of myocardial revascularization in non-stable stenocardia].
Захаров, Ks, D., Gazarian, G. A., Galankina, I. E., Д., К. С., Prelovskaia, G. I., Babaian, I. S., & Марсовна, Б. Н. (2007) · PubMed · Cited by 1 · see citing works
[C-reactive protein in SLE males: contribution to thrombotic complications].
Kliukvina, N. G., Aa, B., Aleksandrova, E. N., & Nasonov, E. L. (1997) · PubMed · Cited by 1 · see citing works
Flagged first, then by citations
Research works printed but not linked: 5
- [19]Zhadin M. N. 2001. Review of russian literature on biological action of DC and low-frequency AC magnetic fields. Bioelectromagnetics 22, 27–45 [DOI] [PubMed] [Google Scholar]
- [20]Chizhevsky A. 1936. The terrestrial echo of solar storms. Moscow: Idea [Google Scholar]
- [40]WHO 2007. Extremely low frequency fields. Environmental Health Criteria Monograph no. 238. [cited 18 November 2011] [Google Scholar]
- [42]Phillips J. B., Deutschlander M. 1997. Magnetoreception in terrestrial vertebrates: Implications for possible mechanisms of EMF interaction with biological systems. In The Melatonin hypothesis: electric power and the risk of breast cancer, pp. 111–172 [Google Scholar]
- [80]DeMarch B. G. E., DeWit C. A., Muir D. C. G. 2008. Dispersal–migration. Environ. Toxicol. Chem. 17, 88–98 [Google Scholar]
Cited by
Sorted by citations
Quantum effects in the brain: A review
Adams, B., & Petruccione, F. (2020) · AVS Quantum Science · doi:10.1116/1.5135170 · Cited by 80 · see citing works
Magnetocarcinogenesis: is there a mechanism for carcinogenic effects of weak magnetic fields?
Juutilainen, J., Herrala, M., Luukkonen, J., Naarala, J., & Hore, P. J. (2018) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2018.0590 · Cited by 62 · see citing works
Lunar biological effects and the magnetosphere
Bevington, M. (2015) · Pathophysiology · doi:10.1016/j.pathophys.2015.08.005 · Cited by 50 · see citing works
Biological effects related to geomagnetic activity and possible mechanisms
Крылов, В. В. (2017) · Bioelectromagnetics · doi:10.1002/bem.22062 · Cited by 50 · see citing works
The Possible Effect of Space Weather Factors on Various Physiological Systems of the Human Organism
Zenchenko, T. A., & Breus, T. K. (2021) · Atmosphere · doi:10.3390/atmos12030346 · Cited by 45 · see citing works
Upper bound on the biological effects of 50/60 Hz magnetic fields mediated by radical pairs
Hore, P. J. (2019) · eLife · doi:10.7554/elife.44179 · Cited by 43 · see citing works
Крылов, В. В., Зотов, О. Д., Klain, B. I., Ушакова, Н. В., Канцерова, Н. П., Znobisheva, A. V., Izyumov, Y. G., Кузьмина, В. В., Morozov, A. A., Лысенко, Л. А., et al. (2014) · Journal of Atmospheric and Solar-Terrestrial Physics · doi:10.1016/j.jastp.2014.01.020 · Cited by 41 · see citing works
Why are living things sensitive to weak magnetic fields?
Liboff, A. R. (2013) · Electromagnetic Biology and Medicine · doi:10.3109/15368378.2013.809579 · Cited by 35 · see citing works
Wan, G., Wang, W., Xu, J., Yang, Q., Dai, M.-J., Zhang, F., Sword, G. A., Pan, W., & Chen, F. (2015) · PLoS ONE · doi:10.1371/journal.pone.0132966 · Cited by 33 · see citing works
Consequences of “natural” disasters on aquatic life and habitats
Cooke, S. J., Galassi, D. M. P., Gillanders, B. M., Landsman, S. J., Hammerschlag, N., Gallagher, A. J., Eliason, E. J., Kraft, C. E., Taylor, M. K., Crisafulli, C. M., et al. (2022) · Environmental Reviews · doi:10.1139/er-2022-0050 · Cited by 32 · see citing works
Cifra, M., Apollonio, F., Liberti, M., García-Sánchez, T., & Mir, L. M. (2020) · International Journal of Biometeorology · doi:10.1007/s00484-020-01885-1 · Cited by 26 · see citing works
Sajedi, S. A., & Abdollahi, F. (2012) · BMC Neurology · doi:10.1186/1471-2377-12-100 · Cited by 24 · see citing works
Orientational behavior of animals with the geomagnetic field and mechanisms of magnetoreception
Крылов, В. В., Osipova, E. A., & Izyumov, Y. G. (2015) · Izvestiya Atmospheric and Oceanic Physics · doi:10.1134/s0001433815070051 · Cited by 22 · see citing works
The possible effects of the solar and geomagnetic activity on multiple sclerosis
Papathanasopoulos, P., Preka-Papadema, P., Gkotsinas, A., Dimisianos, N., Hillaris, A., Katsavrias, C., Antonakopoulos, G. A., Moussas, X. D., Andreadou, E., Georgiou, V. L., et al. (2016) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2016.04.023 · Cited by 18 · see citing works
Крылов, В. В., Канцерова, Н. П., Лысенко, Л. А., & Osipova, E. A. (2019) · International Journal of Biometeorology · doi:10.1007/s00484-018-01657-y · Cited by 17 · see citing works
Hagstrum, J. T. (2023) · Journal of Comparative Physiology A · doi:10.1007/s00359-023-01627-9 · Cited by 15 · see citing works
Рожков, В. П., Belisheva, N. K., Александровна, М. А., & Si, S. (2014) · Human Physiology · doi:10.1134/s0362119714040124 · Cited by 15 · see citing works
Williams, B. J. (2022) · Journal of Scientific Exploration · doi:10.31275/20212359 · Cited by 12 · see citing works
Revisiting the connection between Solar eruptions and primary headaches and migraines using Twitter
Milojević, S. (2016) · Scientific Reports · doi:10.1038/srep39769 · Cited by 11 · see citing works
The response of Daphnia magna Straus to long-term exposure to simulated geomagnetic storms
Крылов, В. В., & Osipova, E. A. (2019) · Life Sciences in Space Research · doi:10.1016/j.lssr.2019.04.004 · Cited by 8 · see citing works
A study of correlation between seismicity and mental health: Crete, 2008–2010
Anagnostopoulos, G. C., Basta, M., Stefanakis, Z., Vassiliadis, V. G., Vgontzas, A. N., Rigas, A. G., Koutsomitros, S. T., Balogiannis, S., & Papadopoulos, G. (2013) · Geomatics Natural Hazards and Risk · doi:10.1080/19475705.2013.819385 · Cited by 8 · see citing works
Close, J. P. (2014) · Hypothesis · doi:10.5779/hypothesis.v12i1.359 · Cited by 7 · see citing works
Self-citationA human source for ELF magnetic perturbations
Liboff, A. R. (2016) · Electromagnetic Biology and Medicine · doi:10.3109/15368378.2015.1107841 · Cited by 7 · see citing works
McDonnell, A. (2014) · Journal of Behavioral and Brain Science · doi:10.4236/jbbs.2014.47035 · Cited by 6 · see citing works
Esquivel, D. M. S., Corrêa, A. A. C., Vaillant, O. S., de Melo, V. B., Gouvêa, G. S., Ferreira, C. G., Ferreira, T. A., & Wajnberg, E. (2014) · Die Naturwissenschaften · doi:10.1007/s00114-014-1147-5 · Cited by 6 · see citing works
Henshaw, D. L., & Philips, A. (2024) · International Journal of Radiation Biology · doi:10.1080/09553002.2024.2435329 · Cited by 5 · see citing works
Davis, G. E., & Lowell, W. E. (2013) · Clinical Epigenetics · doi:10.1186/1868-7083-5-5 · Cited by 4 · see citing works
Liboff, A. R. (2013) · Electromagnetic Biology and Medicine · doi:10.3109/15368378.2012.739980 · Cited by 3 · see citing works
Крылов, В. В., Papchenkova, G. A., & Osipova, E. A. (2020) · Bioelectromagnetics · doi:10.1002/bem.22264 · Cited by 3 · see citing works
A possible role of space weather in the events surrounding theTitanicdisaster
Zinkova, M. (2020) · Weather · doi:10.1002/wea.3817 · Cited by 3 · see citing works
Kaspranski, R. R., Binhi, V. N., & Koshel, I. V. (2025) · Life · doi:10.3390/life15111766 · Cited by 2 · see citing works
Influence of geomagnetic disturbances on myocardial infarctions in women and men from Brazil
Rezende, L. F. C., de Paula, E. R., Muella, M. T. A. H., Dutra, S. L. G., Rosa, R. R., Saldiva, P. H. N., & Ometto, J. P. (2025) · Communications Medicine · doi:10.1038/s43856-025-00887-7 · Cited by 2 · see citing works
Expression of CRY2 Gene in the Brain Is Related to Human Navigation
Xu, S., Kong, X., & Jia Liu, B. (2021) · Frontiers in Radiology · doi:10.3389/fradi.2021.731070 · Cited by 2 · see citing works
Temuryants, N. A., Tumanyants, K. N., Хусаинов, Д. Р., Черетаев, И. В., & Tumanyants, E. N. (2017) · Izvestiya Atmospheric and Oceanic Physics · doi:10.1134/s0001433817070088 · Cited by 2 · see citing works
Captura de Langosta en Baja California y su relación con la Actividad Solar
Figueredo, P. S., de la Torre, B. H., Vega‐Velázquez, A., & Vega-Bolaños, A. (2021) · Revista Iberoamericana de Bioeconomía y Cambio Climático · doi:10.5377/ribcc.v7i13.11262 · Cited by 2 · see citing works
JSE 28:4 Winter 2014 Whole Issue PDF
Erickson, K. E. (2014) · Journal of Scientific Exploration · Cited by 1 · see citing works
Impairment in behavioral sedation in rats during periods of elevated global geomagnetic activity
Fournier, N. M. (2019) · International Journal of Biometeorology · doi:10.1007/s00484-019-01741-x · Cited by 1 · see citing works
Current knowledge of lunar synchronized spawning in fish
Fukunaga, K., & Takemura, A. (2025) · Chronobiology International · doi:10.1080/07420528.2025.2591924 · Cited by 1 · see citing works
Geomagnetic activity and human reproduction in the Far North
Borisenkov, M. F., Kozlovskaya, A. V., & Bojko, E. R. (2018) · Biological Rhythm Research · doi:10.1080/09291016.2018.1513631 · Cited by 1 · see citing works
Otsuka, K., Cornélissen, G., & Franz Halberg, A. (2016) · Springer eBooks · doi:10.1007/978-4-431-54631-3_13 · Cited by 1 · see citing works
Sajedi, S. A., & Abdollahi, F. (2016) · arXiv (Cornell University) · doi:10.48550/arxiv.1611.01448 · Cited by 1 · see citing works
Tombarkiewicz, B., Bojarski, B., Olesek, A., Pawlak, K., Kanik, W., Wojnar, T., Marcin Wojciech, L. I. S., & Socha, M. (2018) · Folia Biologica · doi:10.3409/fb_66-4.16
Gurfinkel, Y. I., Pishchalnikov, R. Y., & Tishin, A. M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822532-5.00009-1
Solar and Geomagnetic Activity is Associated with Reduced Renal Function Among Elderly MalesPreprint
Wang, Y., Vieira, C. L. Z., Garshick, E., Schwartz, J. D., Vokonas, P., & Koutrakis, P. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4513156
The radical pair mechanism of biological effects on hypomagnetic fields and one method to verify it
Ouyang, J.-H. (2023) · Journal of Life Sciences Research · doi:10.20448/lifsc.v10i1.4954
Fong-Isariyawongse, J. S. (2025) · doi:10.64628/aai.59adajj9m
Bartsch, H., Seebald, E., Küpper, H., Probst, H., & Bartsch, C. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-33018-6.00008-7
Martel, J. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-33018-6.00005-1
Aurora‐Associated Geomagnetic Activity and Health: A Review With Focus on Neurological Implications
Sethi, Y., Vora, V., Verma, A., Bhatt, R., Chaudhary, M. S., Chopra, H., & Greig, N. H. (2026) · GeoHealth · doi:10.1029/2025gh001710
- Authors
- Close, J.
- Affiliations
- Isis Green, Oxford, UK
- Corresponding author
- Close, James
- Venue
- Proceedings of the Royal Society B: Biological Sciences
- Publisher
- The Royal Society
- Published
- 2012-03-14
- Volume
- 279
- Issue
- 1736
- Pages
- 2081-2090
- ISSN
- 0080-4649 (ISSN-L)
- 0962-8452
- 1471-2954
- PMC
- PMC3321722
- OpenAlex
- W2140070502
- Cited by
- 49
- References
- 104
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 3 · 2020: 4 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 5 · 2015: 3 · 2014: 6 · 2013: 4 · 2012: 1
- FWCI
- 2.05
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the Royal Society B Biological Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Electromagnetic Fields and Biological Effects
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Geomagnetism and Paleomagnetism Studies
- Keywords
- geomagnetic storms, cryptochrome, magnetoreception, stress response, hypothalamic-pituitary-adrenal axis, melatonin, circadian rhythm, zeitgebers, geomagnetic field, human health effects, dispersal strategies, disorientation
- MeSH terms
- Adrenal Glands, Animals, Circadian Rhythm, Humans, Hypothalamus, Light, Melatonin, Pituitary Gland, Stress, Physiological, Animal Migration, Cryptochromes, Magnetic Phenomena
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review