Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak
Open accessAbstract
Background: Recent surge of olfactory dysfunction in patients who were referred to ENT clinics and concurrent COVID-19epidemic in Iran motivated us to evaluate anosmic/hyposmic patients to find any relation between these two events. Methods: This is a cross-sectional study with an online checklist on voluntary cases in all provinces of Iran between the 12th and 17th March, 2020. Cases was defined as self-reported anosmia/hyposmia in responders fewer than 4 weeks later (from start the of COVID-19 epidemic in Iran). Variables consist of clinical presentations, related past medical history, family history of recent respiratory tract infection and hospitalization. Results: In this study 10069 participants aged 32.5±8.6 (7-78) years, 71.13% female and 81.68% non-smoker completed online checklist. They reported 10.55% a history of a trip out of home town and 1.1% hospitalization due to respiratory problems recently. From family members 12.17% had a history of severe respiratory disease in recent days and 48.23% had anosmia/hyposmia. Correlation between the number of olfactory disorder and reported COVID-19 patients in all 31 provinces till 16th March 2020 was highly significant (Spearman correlation coefficient=0.87, p-Value<0.001). The onset of anosmia was sudden in 76.24% and till the time of filling the questionnaire in 60.90% of patients decreased sense of smell was constant. Also 83.38 of this patients had decreased taste sensation in association with anosmia. Conclusions: It seems that we have a surge in outbreak of olfactory dysfunction happened in Iran during the COVID-19 epidemic. The exact mechanism of anosmia/hyposmia in COVID-19 patients’ needs further investigations.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Clinical reports indicate that SARS-CoV-2 infection is associated with high rates of disturbances in smell and taste perception, including anosmia.
“Clinical reports suggest that infection with CoV-2 is associated with high rates of disturbances in smell and taste perception, including anosmia (8-13).”
From Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia (2020) · cites this paper as [8]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak
Rothan, H. A., & Byrareddy, S. N. (2020) · Journal of Autoimmunity · doi:10.1016/j.jaut.2020.102433 · Cited by 5,840 · see citing works
Lechien, J. R., Chiesa-Estomba, C. M., De Siati, D. R., Horoi, M., Le Bon, S. D., Rodriguez, A., Dequanter, D., Blecic, S., El Afia, F., Distinguin, L., et al. (2020) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-020-05965-1 · Cited by 2,668 · see citing works
Baig, A. M., Khaleeq, A., Ali, U., & Syeda, H. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00122 · Cited by 2,207 · see citing works
Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
Li, G., & Clercq, E. D. (2020) · Nature Reviews Drug Discovery · doi:10.1038/d41573-020-00016-0 · Cited by 1,739 · see citing works
Mao, L., Wang, M., Chen, S., He, Q., Chang, J., Hong, C., Zhou, Y., Wang, D., Miao, X., Hu, Y., et al. (2020) · medRxiv · doi:10.1101/2020.02.22.20026500 · Cited by 882 · see citing works
Position paper on olfactory dysfunction
Hummel, T. R., Whitcroft, K. L., Andrews, P. J., Altundağ, A., Cinghi, C., Costanzo, R. M., Damm, M., Frasnelli, J., Gudziol, H., Gupta, N., et al. (2017) · Rhinology Journal · doi:10.4193/rhino16.248 · Cited by 846 · see citing works
Yan, C. H., Faraji, F., Prajapati, D. P., Boone, C. E., & DeConde, A. S. (2020) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22579 · Cited by 754 · see citing works
Chan, K. W., Wong, V. T., & Tang, S. C. W. (2020) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x20500378 · Cited by 396 · see citing works
Identification of Viruses in Patients With Postviral Olfactory Dysfunction
Suzuki, M., Saito, K., Min, W., Vladau, C., Toida, K., Itoh, H., & Murakami, S. (2007) · The Laryngoscope · doi:10.1097/01.mlg.0000249922.37381.1e · Cited by 383 · see citing works
Seiden, A. M. (2004) · Otolaryngologic Clinics of North America · doi:10.1016/j.otc.2004.06.007 · Cited by 225 · see citing works
Complaints of olfactory disorders: epidemiology, assessment and clinical implications
Nordin, S., & Brämerson, A. (2008) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e3282f3f473 · Cited by 173 · see citing works
Biopsies of Human Olfactory Epithelium
Jafek, B. W. (2002) · Chemical Senses · doi:10.1093/chemse/27.7.623 · Cited by 161 · see citing works
Effect of olfactory bulb ablation on spread of a neurotropic coronavirus into the mouse brain.
Perlman, S. M., Evans, G., & Afifi, A. K. (1990) · The Journal of Experimental Medicine · doi:10.1084/jem.172.4.1127 · Cited by 129 · see citing works
GMS current topics in otorhinolaryngology, head and neck surgery
Hals-Nasen-Ohrenheilkunde, K. U. H. D. G. F. (2004) · Cited by 122 · see citing works
Mohammed, A. K., Magnusson, O., Mæhlen, J., Fonnum, F., Norrby, E., Schultzberg, M., & Kristensson, K. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90089-m · Cited by 55 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Brann, D. H., Tsukahara, T., Weinreb, C., Lipovsek, M., Van den Berge, K., Gong, B., Chance, R., Macaulay, I. C., Chou, H.-J., Fletcher, R. B., et al. (2020) · Science Advances · doi:10.1126/sciadv.abc5801 · Cited by 1,198 · see citing works
International consensus statement on allergy and rhinology: rhinosinusitis 2021
Orlandi, R. R., Kingdom, T. T., Smith, T. L., Bleier, B. S., DeConde, A. S., Luong, A., Poetker, D. M., Soler, Z. M., Welch, K. C., Wise, S. K., et al. (2020) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22741 · Cited by 1,051 · see citing works
Smell dysfunction: a biomarker for COVID‐19
Moein, S. T., Hashemian, S. M. R., Mansourafshar, B., Khorram‐Tousi, A., Tabarsi, P., & Doty, R. L. (2020) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22587 · Cited by 793 · see citing works
Yan, C. H., Faraji, F., Prajapati, D. P., Boone, C. E., & DeConde, A. S. (2020) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22579 · Cited by 754 · see citing works
Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services
Søreide, K., Hallet, J. I., Matthews, J. B., Schnitzbauer, A. A., Line, P., Lai, P. B. S., Otero, J., Callegaro, D., Warner, S. G., Baxter, N. N., et al. (2020) · British journal of surgery · doi:10.1002/bjs.11670 · Cited by 697 · see citing works
Tong, J. Y., Wong, A., Zhu, D., Fastenberg, J. H., & Tham, T. (2020) · Otolaryngology · doi:10.1177/0194599820926473 · Cited by 614 · see citing works
Neurological manifestations and complications of COVID-19: A literature review
Ahmad, I., & Rathore, F. A. (2020) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2020.05.017 · Cited by 548 · see citing works
More Than Smell—COVID-19 Is Associated With Severe Impairment of Smell, Taste, and Chemesthesis
Parma, V., Ohla, K., Veldhuizen, M. G., Niv, M. Y., Kelly, C. E., Bakke, A. J., Cooper, K. W., Bouysset, C., Pirastu, N., Dibattista, M., et al. (2020) · Chemical Senses · doi:10.1093/chemse/bjaa041 · Cited by 503 · see citing works
Self-citationCOVID-19 and anosmia: A review based on up-to-date knowledge
Meng, X., Deng, Y., Dai, Z., & Meng, Z. (2020) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2020.102581 · Cited by 407 · see citing works
COVID‐19 Anosmia Reporting Tool: Initial Findings
Kaye, R. J., Chang, C. W. D., Kazahaya, K., Brereton, J. M., & Denneny, J. C. (2020) · Otolaryngology · doi:10.1177/0194599820922992 · Cited by 389 · see citing works
Beltrán‐Corbellini, Á., Chico‐García, J. L., Martínez‐Poles, J., Rodríguez‐Jorge, F., Natera‐Villalba, E., Gómez-Corral, J., López, A. G., Monreal, E., Parra‐Díaz, P., Cortes-Cuevas, J. L., et al. (2020) · European Journal of Neurology · doi:10.1111/ene.14273 · Cited by 362 · see citing works
von Bartheld, C. S., Hagen, M. M., & Butowt, R. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00460 · Cited by 283 · see citing works
ACE2, TMPRSS2 distribution and extrapulmonary organ injury in patients with COVID-19
Dong, M., Zhang, J., Ma, X., Tan, J., Chen, L., Liu, S., Xin, Y., & Zhuang, L. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110678 · Cited by 259 · see citing works
Neurological and Neuropsychiatric Impacts of COVID-19 Pandemic
Roy, D., Ghosh, R., Dubey, S., Dubey, M. J., Benito‐León, J., & Ray, B. K. (2020) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/cjn.2020.173 · Cited by 228 · see citing works
Neurological manifestations of COVID-19: a systematic review and meta-analysis of proportions
Favas, T. T., Dev, P., Chaurasia, R. N., Chakravarty, K., Mishra, R., Joshi, D., Mishra, V. N., Kumar, A., Singh, V. K., Pandey, M., et al. (2020) · Neurological Sciences · doi:10.1007/s10072-020-04801-y · Cited by 211 · see citing works
Hannum, M. E., Ramirez, V. A., Lipson, S. J., Herriman, R. D., Toskala, A. K., Lin, C., Joseph, P. V., & Reed, D. R. (2020) · Chemical Senses · doi:10.1093/chemse/bjaa064 · Cited by 204 · see citing works
Risk factors prediction, clinical outcomes, and mortality in COVID‐19 patients
Alizadehsani, R., Sani, Z. A., Behjati, M., Roshanzamir, Z., Hussain, S., Abedini, N., Hasanzadeh, F., Khosravi, A., Shoeibi, A., Roshanzamir, M., et al. (2020) · Journal of Medical Virology · doi:10.1002/jmv.26699 · Cited by 168 · see citing works
Is loss of sense of smell a diagnostic marker in COVID‐19: A systematic review and meta‐analysis
Rocke, J., Hopkins, C. L., Philpott, C. M., & Kumar, B. N. (2020) · Clinical Otolaryngology · doi:10.1111/coa.13620 · Cited by 156 · see citing works
COVID-19, SARS and MERS: A neurological perspective
Kwong, K. C. N. K., Mehta, P. R., Shukla, G., & Mehta, A. R. (2020) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2020.04.124 · Cited by 154 · see citing works
Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report
Karimi‐Galougahi, M., Ghorbani, J., Karam, M. B., Naeini, A. S., & Haseli, S. (2020) · Academic Radiology · doi:10.1016/j.acra.2020.04.002 · Cited by 155 · see citing works
Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak in Iran
Bagheri, S. H., Asghari, A., Farhadi, M. R., Shamshiri, A. R., Kabir, A., Kamrava, S. K., Jalessi, M., Mohebbi, A., Alizadeh, R., Honarmand, A. A., et al. (2020) · Medical Journal of the Islamic Republic of Iran · doi:10.47176/mjiri.34.62 · Cited by 154 · see citing works
Self-citationA primer on viral‐associated olfactory loss in the era of COVID‐19
Soler, Z. M., Patel, Z. M., Turner, J. H., & Holbrook, E. H. (2020) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22578 · Cited by 146 · see citing works
Jha, N. K., Ojha, S. K., Jha, S. K., Dureja, H., Singh, S. K., Shukla, S. D., Chellappan, D. K., Gupta, G., Bhardwaj, S., Kumar, N., et al. (2021) · Journal of Molecular Neuroscience · doi:10.1007/s12031-020-01767-6 · Cited by 151 · see citing works
Borsetto, D., Hopkins, C., Philips, V., Obholzer, R., Tirelli, G., Polesel, J., Calvanese, L., & Boscolo-Rizzo, P. (2020) · Rhinology · doi:10.4193/rhin20.185 · Cited by 138 · see citing works
Anosmia as a Prominent Symptom of COVID-19 Infection
Heidari, F., Karimi, E., Firouzifar, M., Khamushian, P., Ansari, R., Ardehali, M. M., & Heidari, F. (2020) · Rhinology Journal · doi:10.4193/rhin20.140 · Cited by 134 · see citing works
CNS implications of COVID-19: a comprehensive review
Nagu, P., Parashar, A., Behl, T., & Mehta, V. (2020) · Reviews in the Neurosciences · doi:10.1515/revneuro-2020-0070 · Cited by 131 · see citing works
Olfactory Dysfunction: A Highly Prevalent Symptom of COVID‐19 With Public Health Significance
Sedaghat, A. R., Gengler, I. M., & Speth, M. M. (2020) · Otolaryngology · doi:10.1177/0194599820926464 · Cited by 123 · see citing works
A Review of Neurological Complications of COVID-19
Sheraton, M., Deo, N., Kashyap, R., & Surani, S. (2020) · Cureus · doi:10.7759/cureus.8192 · Cited by 115 · see citing works
Romoli, M., Jelčić, I., Bernard‐Valnet, R., Azorín, D. G., Mancinelli, L., Akhvlediani, T., Monaco, S., Taba, P., & Sellner, J. (2020) · European Journal of Neurology · doi:10.1111/ene.14382 · Cited by 111 · see citing works
COVID-19: Review of a 21st Century Pandemic from Etiology to Neuro-psychiatric Implications
Yamamoto, V., Bolanos, J. F., Fiallos, J., Strand, S. E., Morris, K., Shahrokhinia, S., Cushing, T. R., Hopp, L., Tiwari, A., Hariri, R., et al. (2020) · Journal of Alzheimer's Disease · doi:10.3233/jad-200831 · Cited by 100 · see citing works
18FDG PET/CT Scan Reveals Hypoactive Orbitofrontal Cortex in Anosmia of COVID-19
Karimi‐Galougahi, M., Yousefi-Koma, A., Karam, M. B., Raad, N., & Haseli, S. (2020) · Academic Radiology · doi:10.1016/j.acra.2020.04.030 · Cited by 95 · see citing works
Olfactory Dysfunction in the COVID-19 Outbreak
Izquierdo-Domínguez, A., Rojas‐Lechuga, M. J., Mullol, J., & Alobid, I. (2020) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0567 · Cited by 95 · see citing works
Kanjanaumporn, J., Aeumjaturapat, S., Snidvongs, K., Seresirikachorn, K., & Chusakul, S. (2020) · Asian Pacific Journal of Allergy and Immunology · doi:10.12932/ap-030520-0826 · Cited by 91 · see citing works
The Neurologic Manifestations of Coronavirus Disease 2019 Pandemic: A Systemic Review
Tsai, S.-T., Lu, M., San, S., & Tsai, C. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00498 · Cited by 87 · see citing works
Coronaviruses and the Chemical Senses: Past, Present, and Future
Pellegrino, R., Cooper, K. W., Pizio, A. D., Joseph, P. V., Bhutani, S., & Parma, V. (2020) · Chemical Senses · doi:10.1093/chemse/bjaa031 · Cited by 86 · see citing works
Neto, D. B., Fornazieri, M. A., Dib, C., Francesco, R. C. D., Doty, R. L., Voegels, R. L., & Pinna, F. D. R. (2020) · Otolaryngology · doi:10.1177/0194599820954825 · Cited by 86 · see citing works
Cytokine storm induced by SARS-CoV-2 infection: The spectrum of its neurological manifestations
Thepmankorn, P., Bach, J. R., Lasfar, A., Zhao, X., Souayah, S., Chong, Z. Z., & Souayah, N. (2020) · Cytokine · doi:10.1016/j.cyto.2020.155404 · Cited by 86 · see citing works
The role of self-reported smell and taste disorders in suspected COVID‑19
Printza, A., & Constantinidis, J. (2020) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-020-06069-6 · Cited by 85 · see citing works
Hassanzadeh, K., Pérez‐Peña, H., Dragotto, J., Buccarello, L., Iorio, F., Pieraccini, S., Sancini, G., & Feligioni, M. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00373 · Cited by 84 · see citing works
SARS-CoV-2 Dissemination Through Peripheral Nerves Explains Multiple Organ Injury
Fenrich, M., Mrdenovic, S., Balog, M., Tomic, S., Zjalic, M., Roncevic, A., Mandic, D., Debeljak, Z., & Heffer, M. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00229 · Cited by 95 · see citing works
Ear nose throat-related symptoms with a focus on loss of smell and/or taste in COVID-19 patients
Sakallı, E., Temirbekov, D., Bayri, E., Alış, E. E., Erdurak, S. C., & Bayraktaroğlu, M. (2020) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2020.102622 · Cited by 82 · see citing works
Johansson, A., Mohamed, M. S., Moulin, T. C., & Schiöth, H. B. (2021) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2021.577658 · Cited by 78 · see citing works
Predicting novel drugs for SARS-CoV-2 using machine learning from a >10 million chemical space
Kowalewski, J., & Ray, A. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e04639 · Cited by 76 · see citing works
Olfactory and gustatory abnormalities in COVID-19 cases
Altın, F., Cingi, C., Uzun, T., & Bal, C. (2020) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-020-06155-9 · Cited by 75 · see citing works
Samaranayake, L. P., Fakhruddin, K. S., & Panduwawala, C. (2020) · Acta Odontologica Scandinavica · doi:10.1080/00016357.2020.1787505 · Cited by 74 · see citing works
Oliver, N., Barber, X., Roomp, K., & Roomp, K. (2020) · Journal of Medical Internet Research · doi:10.2196/21319 · Cited by 73 · see citing works
Effects of Environmental Factors on Severity and Mortality of COVID-19
Kifer, D., Bugada, D., Villar-García, J., Gudelj, I., Menni, C., Sudre, C. H., Vučković, F., Ugrina, I., Lorini, F. L., Posso, M., et al. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2020.607786 · Cited by 67 · see citing works
SARS-CoV2 entry and spread in the lymphatic drainage system of the brain
Bostancıklıoğlu, M. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.04.080 · Cited by 69 · see citing works
Role of a habitat's air humidity in Covid-19 mortality
Biktasheva, I. V. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.138763 · Cited by 66 · see citing works
The close relationship between sudden loss of smell and COVID-19
Joffily, L., Ungierowicz, A., David, A. G., Melo, B., Brito, C. L. T., Mello, L. F., dos Santos, P. D. S. C., & Pezato, R. (2020) · Brazilian Journal of Otorhinolaryngology · doi:10.1016/j.bjorl.2020.05.002 · Cited by 59 · see citing works
Li, W., Li, M., & Ou, G. (2020) · FEBS Journal · doi:10.1111/febs.15491 · Cited by 56 · see citing works
Anosmia: a missing link in the neuroimmunology of coronavirus disease 2019 (COVID-19)
Yazdanpanah, N., Saghazadeh, A., & Rezaei, N. (2020) · Reviews in the Neurosciences · doi:10.1515/revneuro-2020-0039 · Cited by 57 · see citing works
Olfactory Bulb Signal Abnormality in Patients with COVID-19 Who Present with Neurologic Symptoms
Strauß, S., Lantos, J. E., Heier, L., Shatzkes, D. R., & Phillips, C. D. (2020) · American Journal of Neuroradiology · doi:10.3174/ajnr.a6751 · Cited by 53 · see citing works
Hypogeusia as the initial presenting symptom of COVID-19
Melley, L. E., Bress, E., & Polan, E. (2020) · BMJ Case Reports · doi:10.1136/bcr-2020-236080 · Cited by 49 · see citing works
Bellocchio, L., Bordea, I. R., Ballini, A., Lorusso, F., Hazballa, D., Isacco, C. G., Malcangi, G., Inchingolo, A. D., Dipalma, G., Inchingolo, F., et al. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17218049 · Cited by 50 · see citing works
Dolatshahi, M., Sabahi, M., & Aarabi, M. H. (2021) · Molecular Neurobiology · doi:10.1007/s12035-020-02236-2 · Cited by 49 · see citing works
Quantitative Assessment of Olfactory Dysfunction Accurately Detects Asymptomatic COVID-19 Carriers
Bhattacharjee, A. S., Joshi, S. V., Naik, S., Sangle, S. A., & Abraham, N. M. (2020) · EClinicalMedicine · doi:10.1016/j.eclinm.2020.100575 · Cited by 47 · see citing works
Is SARS‐CoV‐2 (COVID‐19) postviral olfactory dysfunction (PVOD) different from other PVOD?
Imam, S. A., Lao, W. P., Reddy, P. D., Nguyen, S. A., & Schlosser, R. J. (2020) · World Journal of Otorhinolaryngology - Head and Neck Surgery · doi:10.1016/j.wjorl.2020.05.004 · Cited by 46 · see citing works
Anosmia and ageusia associated with coronavirus infection (COVID‑19) - what is known?
Tanasa, I., Manciuc, C. D., Cărăuleanu, A., Navolan, D. B., Bohîlțea, R. E., & Nemescu, D. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.8808 · Cited by 39 · see citing works
Olfactory and taste disorders in healthcare workers with COVID-19 infection
Villarreal, I. M., Morato, M., Martínez-Ruiz-Coello, M. D. M., Navarro, A., García-Chillerón, R., Ruiz, Á., de Almeida, I. V., Mazón, L., & Plaza, G. (2020) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-020-06237-8 · Cited by 39 · see citing works
COVID-19: Post-recovery long-term symptoms among patients in Saudi Arabia
Khodeir, M. M., Shabana, H. A., Rasheed, Z., Alkhamiss, A. S., Khodeir, M., Alkhowailed, M. S., Alharbi, S., Alsoghair, M., Alsagaby, S. A., & Abdulmonem, W. A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0260259 · Cited by 36 · see citing works
Rising evidence for neurological involvement in COVID-19 pandemic
Calcagno, N., Colombo, E., Maranzano, A., Pasquini, J., Sarmiento, I. J. K., Trogu, F., & Silani, V. (2020) · Neurological Sciences · doi:10.1007/s10072-020-04447-w · Cited by 33 · see citing works
Neurological Consequences of 2019-nCoV Infection: A Comprehensive Literature Review
Azim, D., Nasim, S., Kumar, S., Hussain, A., & Patel, S. (2020) · Cureus · doi:10.7759/cureus.8790 · Cited by 32 · see citing works
Diegritz, C., Manhart, J., Bücher, K., Grabein, B., Schuierer, G., Kühnisch, J., Kunzelmann, K., Hickel, R., & Fotiadou, C. (2020) · Clinical Oral Investigations · doi:10.1007/s00784-020-03440-z · Cited by 32 · see citing works
Characteristics of COVID-19 smell and taste dysfunction in hospitalized patients
Husain, Q. M., Kokinakos, K., Kuo, Y., Zaidi, F., Houston, S., & Shargorodsky, J. (2021) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2021.103068 · Cited by 31 · see citing works
Manifestaciones clínicas de la COVID-19
Benítez, T. P., Rojas, A. L., Báez, L. M., Orozco, A. C. M., Avendaño, A. R. D., Corona-Villalobos, C. A., Guzmán-Valderrábano, C., Rangel, L. G. G., Lechuga-Trejo, I., Ramírez, B. A. A., et al. (2020) · Revista Latinoamericana de Infectología Pediátrica · doi:10.35366/96668 · Cited by 31 · see citing works
Coelho, D. H., Kons, Z. A., Costanzo, R. M., & Reiter, E. R. (2020) · Otolaryngology · doi:10.1177/0194599820929957 · Cited by 30 · see citing works
The unfolding palette of COVID-19 multisystemic syndrome and its neurological manifestations
Barrantes, F. J. (2021) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2021.100251 · Cited by 28 · see citing works
Overview of COVID-19 and neurological complications
Hosseini, N., Nadjafi, S., & Ashtari, B. (2021) · Reviews in the Neurosciences · doi:10.1515/revneuro-2020-0116 · Cited by 27 · see citing works
Single-cell atlas of a non-human primate reveals new pathogenic mechanisms of COVID-19Preprint
Han, L., Wei, X., Liu, C., Volpe, G., Wang, Z., Pan, T., Yuan, Y., Lei, Y., Lai, Y., Ward, C., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.10.022103 · Cited by 28 · see citing works
Karni, N., Klein, H., Asseo, K., Benjamini, Y., Israel, S., Nammary, M., Olshtain‐Pops, K., Nir‐Paz, R., Hershko, A. Y., Muszkat, M., et al. (2020) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofaa589 · Cited by 27 · see citing works
The Association of Smell and Taste Dysfunction with COVID19, And Their Functional Impacts
Alshakhs, A. M., Almomen, A. A., Yaeesh, I. A., AlOmairin, A., AlMutairi, A. A., Alammar, Z. A., Almomen, H., & AlMomen, Z. I. (2021) · Indian Journal of Otolaryngology and Head & Neck Surgery · doi:10.1007/s12070-020-02330-w · Cited by 26 · see citing works
Neuropathies and neurological dysfunction induced by coronaviruses
Gholami, M., Safari, S., Ulloa, L., & Motaghinejad, M. (2021) · Journal of NeuroVirology · doi:10.1007/s13365-021-00977-x · Cited by 25 · see citing works
Giorli, A., Ferretti, F., Biagini, C., Salerni, L., Bindi, I., Dasgupta, S., Pozza, A., Gualtieri, G., Gusinu, R., Coluccia, A., et al. (2020) · Current Treatment Options in Neurology · doi:10.1007/s11940-020-00641-5 · Cited by 24 · see citing works
Tracking COVID-19 using taste and smell loss Google searches is not a reliable strategy
Asseo, K., Fierro, F., Slavutsky, Y., Frasnelli, J., & Niv, M. Y. (2020) · Scientific Reports · doi:10.1038/s41598-020-77316-3 · Cited by 24 · see citing works
A Microbiome-Driven Approach to Combating Depression During the COVID-19 Pandemic
Ghannoum, M. A., Ford, M., Bonomo, R. A., Gamal, A., & McCormick, T. S. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.672390 · Cited by 24 · see citing works
Anosmia and the Need for COVID‐19 Screening during the Pandemic
Karimi‐Galougahi, M., Raad, N., & Mikaniki, N. (2020) · Otolaryngology · doi:10.1177/0194599820925056 · Cited by 23 · see citing works
Zhao, Y., Liu, Y., Yi, F., Zhang, J., Xu, Z., Liu, Y., & Tao, Y. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.107406 · Cited by 26 · see citing works
Olfactory Dysfunction in Patients With Coronavirus Disease 2019: A Review
Wei, G., Gu, J., Gu, Z., Du, C., Huang, X., Xing, H., Li, L., Zhang, A., Hu, X., & Huo, J.-G. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2021.783249 · Cited by 21 · see citing works
Gastrointestinal Manifestations in COVID-19 Infection and Its Practical Applications
Mandal, A., Konala, V. M., Adapa, S., Naramala, S., & Gayam, V. B. R. (2020) · Cureus · doi:10.7759/cureus.8750 · Cited by 21 · see citing works
Neurological manifestations and complications in patients with covid-19
Ternovykh, I. К., Topuzova, M. P., Chaykovskaya, A. D., Isabekova, P. S., & Alekseeva, T. M. (2020) · Translational Medicine · doi:10.18705/2311-4495-2020-7-3-21-29 · Cited by 20 · see citing works
Bagnasco, D., Passalacqua, G., Braido, F., Tagliabue, E., Cosini, F. F., Filauro, M., Ioppi, A., Carobbio, A. L. C., Mocellin, D., Riccio, A., et al. (2021) · World Allergy Organization Journal · doi:10.1016/j.waojou.2020.100497 · Cited by 19 · see citing works
The Prevalence and Pathophysiology of Chemical Sense Disorder Caused by the Novel Coronavirus
Narayanan, S. N., Shivappa, P., Padiyath, S., Bhaskar, A., Li, Y. W., & Merghani, T. H. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.839182 · Cited by 16 · see citing works
Alshammary, A. F., Alsughayyir, J., Alharbi, K. K., Alsulaiman, A. M., Alshammary, H. F., & Alshammary, H. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.852749 · Cited by 16 · see citing works
Olfactory Dysfunction in Frontline Health Care Professionals During COVID-19 Pandemic in Brazil
Sbrana, M. F., Fornazieri, M. A., Bruni‐Cardoso, A., Avelino‐Silva, V. I., Schechtman, D., Voegels, R. L., Malnic, B., Glezer, I., & Pinna, F. D. R. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.622987 · Cited by 15 · see citing works
Neurological Manifestation of COVID-19: A Literature Review
Azhideh, A., Oskouie, I. M., & Yousefiasl, M. (2020) · International Clinical Neuroscience Journal · doi:10.34172/icnj.2020.20 · Cited by 14 · see citing works
Trachootham, D., Thongyen, S., Lam‐ubol, A., Chotechuang, N., Pongpirul, W. A., & Prasithsirikul, W. (2021) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2021.03.083 · Cited by 13 · see citing works
Neurological complications in patient with COVID-19
Мищенко, Т. С., & Mishchenko, V. M. (2021) · Psychiatry Neurology and Medical Psychology · doi:10.26565/2312-5675-2021-16-03 · Cited by 12 · see citing works
Olfactory dysfunction during COVID-19 pandemic
Izquierdo-Domínguez, A., Rojas‐Lechuga, M. J., Mullol, J., & Alobid, I. (2020) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2020.06.023 · Cited by 12 · see citing works
Olfactory Dysfunction is Associated with More Severe Clinical Course in COVID-19
Tabari, A., Golpayegani, G., Tabari, A., Saedi, B., Mahdkhah, A., Amali, A., Jazinizadeh, S., Sahebi, L., Saffarzadeh, N., & Sadrehosseini, S. M. (2021) · Indian Journal of Otolaryngology and Head & Neck Surgery · doi:10.1007/s12070-021-02507-x · Cited by 10 · see citing works
Ho, B. E., Ho, A. P., Ho, M. A., & Ho, E. C. (2020) · IDCases · doi:10.1016/j.idcr.2020.e00975 · Cited by 12 · see citing works
Swain, S. K. (2020) · International Journal of Otorhinolaryngology and Head and Neck Surgery · doi:10.18203/issn.2454-5929.ijohns20205650 · Cited by 11 · see citing works
Koul, D., Begh, R. A., & Kalsotra, P. (2021) · Indian Journal of Otolaryngology and Head & Neck Surgery · doi:10.1007/s12070-021-02397-z · Cited by 11 · see citing works
Pérdida del sentido del olfato durante la pandemia COVID-19
Izquierdo-Domínguez, A., Rojas‐Lechuga, M. J., Mullol, J., & Alobid, I. (2020) · Medicina Clínica · doi:10.1016/j.medcli.2020.06.006 · Cited by 11 · see citing works
Proposed mechanism for anosmia during COVID-19: The role of local zinc distribution
Equils, O., Lekaj, K., Fattani, S., Wu, A., & Liu, G. C. (2021) · Journal of Translational Science · doi:10.15761/jts.1000397 · Cited by 11 · see citing works
Definitive pathognomonic signs and symptoms of paediatric neurological COVID‐19 are still emerging
Verrottı, A., Mazzocchetti, C., & Iannetti, P. (2021) · Acta Paediatrica · doi:10.1111/apa.15827 · Cited by 11 · see citing works
Olfactory dysfunction incidence and resolution amongst 608 patients with COVID-19 infection
Wu, S. S., Cabrera, C. I., Quereshy, H. A., Kocharyan, A. H., D’Anza, B., & Otteson, T. D. (2023) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2023.103962 · Cited by 11 · see citing works
Acute necrotic hemorrhagic leukoencephalitis related to COVID-19: a report of 2 cases
Alqahtani, A. A., Alaklabi, A., Kristjansson, S., Alharthi, H. A., Aldhilan, S., & Alam, H. (2021) · Radiology Case Reports · doi:10.1016/j.radcr.2021.05.072 · Cited by 10 · see citing works
Anosmia y enfermedad por Coronavirus 2019 (COVID-19): ¿Qué debemos saber?
Sepúlveda, V., Sofía Waissbluth, A., & Claudia González, G. (2020) · Revista de otorrinolaringología y cirugía de cabeza y cuello · doi:10.4067/s0718-48162020000200247 · Cited by 9 · see citing works
Clinical manifestation, laboratory and radiology finding, treatment and outcomes of COVID-19
Nayeri, N. D., Nadali, J., Divani, A., Basirinezhad, M. H., & Meidani, M. (2021) · Journal of Research in Medical Sciences · doi:10.4103/jrms.jrms_900_20 · Cited by 9 · see citing works
- Authors
- Bagheri, S. H., Asghari, A., Farhadi, M., Shamshiri, A. R., Kabir, A., Kamrava, S. K., Jalessi, M., Mohebbi, A., Alizadeh, R., Honarmand, A. A., Ghalehbaghi, B., & Salimi, A.
- Affiliations
- Iran University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
- Iran Medical Council (IR)
- Shahid Beheshti University of Medical Sciences (IR)
- Corresponding author
- Ghalehbaghi, Babak
- ORCID
- Venue
- medRxiv
- Publisher
- openRxiv
- Published
- 2020-03-27
- OpenAlex
- W3013558447
- Cited by
- 179
- References
- 13
- Citations by year
- 2023: 7 · 2022: 11 · 2021: 47 · 2020: 114
- Type
- posted content
- Language
- en
- Open access
- green
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- medRxiv (acceptedVersion, cc-by-nc-nd)
- Topics
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Dermatology › Dermatological and COVID-19 studies
- Keywords
- COVID-19 pandemic, olfactory dysfunction, anosmia, hyposmia, ageusia, SARS-CoV-2, Iran, self-reported symptoms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
